scPDB - Distribution of Binding site Similarity values of 2d0k entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2d0k	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	1.000
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.605
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.585
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.581
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.569
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.568
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.565
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.560
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.560
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.557
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.553
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.550
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.547
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.547
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.541
5hi6	MTX	Dihydrofolate reductase	/	0.540
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.525
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.524
4qi9	MTX	Dihydrofolate reductase	/	0.523
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.519
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.518
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.518
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.517
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.516
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.504
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.503
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.498
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.495
3s3v	TOP	Dihydrofolate reductase	1.5.1.3	0.493
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.491
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.489
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.488
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.486
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.485
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.480
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.478
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.478
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.476
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.476
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.474
1bzf	TMQ	Dihydrofolate reductase	1.5.1.3	0.471
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.468
4elb	34S	Dihydrofolate reductase	/	0.468
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.468
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.467
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.460
1dis	BDM	Dihydrofolate reductase	1.5.1.3	0.459
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.459
4x5h	FOL	Dihydrofolate reductase	1.5.1.3	0.458
2qk8	MTX	Dihydrofolate reductase	/	0.457
4kne	1CY	Dihydrofolate reductase	1.5.1.3	0.453
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.452
1u71	MXA	Dihydrofolate reductase	1.5.1.3	0.450
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.446
1rx6	DDF	Dihydrofolate reductase	1.5.1.3	0.442
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.440