sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 1.000 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.653 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.548 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.539 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.522 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.483 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.479 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.478 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.469 | |
| 1s7n | COA | Acetyl transferase | / | 0.464 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.464 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.463 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.457 | |
| 2zw5 | COA | Bleomycin acetyltransferase | / | 0.457 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.455 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.453 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 1s7l | COA | Acetyl transferase | / | 0.452 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.448 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.446 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.444 | |
| 2zw4 | COA | Bleomycin acetyltransferase | / | 0.444 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.443 |