sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cfc | KPC | 2-(R)-hydroxypropyl-CoM dehydrogenase | 1.1.1.268 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cfc | KPC | 2-(R)-hydroxypropyl-CoM dehydrogenase | 1.1.1.268 | 1.000 | |
| 2bxn | IDB | Serum albumin | / | 0.465 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.465 | |
| 2gn9 | UPG | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.464 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.458 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.458 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 2bxi | AZQ | Serum albumin | / | 0.448 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.447 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.445 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 |