sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cct | 2E1 | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cct | 2E1 | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.766 | |
| 2yi7 | BZ8 | Heat shock protein HSP 90-alpha | / | 0.736 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.734 | |
| 2ye9 | 2D4 | Heat shock protein HSP 90-alpha | / | 0.722 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.721 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.719 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.716 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.692 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.685 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.671 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.656 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.644 | |
| 3ft5 | MO8 | Heat shock protein HSP 90-alpha | / | 0.633 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.627 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.589 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.576 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.571 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.568 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.566 | |
| 2wi2 | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.555 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.553 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.542 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.527 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.526 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 1qy8 | RDI | Endoplasmin | / | 0.519 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2gqp | PA7 | Endoplasmin | / | 0.515 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.515 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.514 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.514 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.509 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.507 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 2fyp | RDE | Endoplasmin | / | 0.504 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.497 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 1u0z | RDC | Endoplasmin | / | 0.492 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2gfd | RDA | Endoplasmin | / | 0.485 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.484 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 2o1u | ANP | Endoplasmin | / | 0.483 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.478 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.477 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 2exl | GDM | Endoplasmin | / | 0.475 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.473 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.472 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2xjg | XJG | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.470 | |
| 4cf8 | V7H | Integrase | / | 0.470 | |
| 2o1v | ADP | Endoplasmin | / | 0.469 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.469 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.468 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.468 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.467 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.466 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 4l9q | 9TP | Serum albumin | / | 0.466 | |
| 2esa | GDM | Endoplasmin | / | 0.465 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.465 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 3qtq | X35 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1gy3 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.463 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3o3p | GDD | Glycosyl transferase, family 2 | / | 0.463 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.463 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.462 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.461 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.461 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.461 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.460 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.460 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 2r3o | 2SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.459 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.458 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.458 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.457 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.457 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.457 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1u2o | NEC | Endoplasmin | / | 0.456 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3ncz | 3NC | Rho-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.456 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3rjc | 06Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.456 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 4hz5 | 19Y | DNA topoisomerase 4 subunit B | / | 0.456 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.456 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.454 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.454 | |
| 3qzf | X66 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4s32 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.453 | |
| 2hch | N5A | Endoplasmin | / | 0.453 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 2qi1 | MZ4 | Gag-Pol polyprotein | / | 0.453 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.453 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.453 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 4ksh | HTT | DNA gyrase subunit B | / | 0.453 | |
| 4xcz | FON | Qdtf | / | 0.453 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.452 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.452 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.452 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4i5c | C5I | Tyrosine-protein kinase JAK1 | / | 0.452 | |
| 1dq8 | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.451 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.451 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.451 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4l78 | ADP | Phosphoribosylformylglycinamidine synthase | / | 0.451 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.450 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 3b9l | AZZ | Serum albumin | / | 0.450 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.450 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.450 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4s34 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2pz8 | APC | NH(3)-dependent NAD(+) synthetase | / | 0.449 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.449 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.448 | |
| 2p3b | 3TL | V-1 protease | / | 0.448 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.448 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3jvh | HHV | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.448 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.448 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.448 | |
| 4ccb | OFG | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.448 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 4l44 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.448 | |
| 1tcw | IM1 | Gag-Pol polyprotein | / | 0.447 | |
| 1z1f | STL | Resveratrol synthase | / | 0.447 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3a8t | ATP | Adenylate isopentenyltransferase | / | 0.447 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.447 | |
| 4cj3 | E4F | Integrase | / | 0.447 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.447 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1t6z | RBF | Riboflavin biosynthesis protein | / | 0.446 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3c4w | ATP | Rhodopsin kinase | / | 0.446 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.446 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.446 | |
| 3o9a | K14 | Pol polyprotein | / | 0.446 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.446 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.446 | |
| 4nt0 | 3DU | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.446 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.446 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2o12 | FMN | Chorismate synthase | / | 0.445 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.445 | |
| 5l3r | GCP | Cell division protein FtsY homolog, chloroplastic | / | 0.445 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.444 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.444 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.444 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.444 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4kio | G5K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 4ksg | 920 | DNA gyrase subunit B | / | 0.444 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.443 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.443 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.443 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.442 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.442 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3lit | E15 | Protease | / | 0.442 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1ei1 | ANP | DNA gyrase subunit B | / | 0.441 | |
| 1mes | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.441 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.441 | |
| 2pyn | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2uvz | GVJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2x4z | X4Z | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.441 | |
| 3ec0 | GRL | Gag-Pol polyprotein | 3.4.23.47 | 0.441 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.441 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3tiz | 3TI | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.441 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.441 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.441 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.441 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.441 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.441 | |
| 4okx | 198 | Androgen receptor | / | 0.441 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.440 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.440 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4mp2 | PV1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.440 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |