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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2cbqTH2Neocarzinostatin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2cbqTH2Neocarzinostatin/1.000
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.454
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.452
2cekN8TAcetylcholinesterase3.1.1.70.446
4bftZVTPantothenate kinase2.7.1.330.443
3sfy3FYUncharacterized protein/0.441
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.440