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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2c9oADPRuvB-like 13.6.4.12

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2c9oADPRuvB-like 13.6.4.121.000
3pfiADPHolliday junction ATP-dependent DNA helicase RuvB/0.465
3zgz84TLeucine--tRNA ligase/0.452
5ayzNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.450
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.449
3kp0Z98D-ornithine 4,5-aminomutase subunit beta/0.445