scPDB - Distribution of Binding site Similarity values of 2c6i entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22	1.000
2r3i	SCF	Cyclin-dependent kinase 2	2.7.11.22	0.624
2r3p	3SC	Cyclin-dependent kinase 2	2.7.11.22	0.610
2r3q	5SC	Cyclin-dependent kinase 2	2.7.11.22	0.563
4fks	46K	Cyclin-dependent kinase 2	2.7.11.22	0.560
2r3f	SC8	Cyclin-dependent kinase 2	2.7.11.22	0.549
2c6l	DT4	Cyclin-dependent kinase 2	2.7.11.22	0.547
3rpv	26Z	Cyclin-dependent kinase 2	2.7.11.22	0.546
3r71	X86	Cyclin-dependent kinase 2	2.7.11.22	0.544
3ezv	EZV	Cyclin-dependent kinase 2	2.7.11.22	0.543
1w8c	N69	Cyclin-dependent kinase 2	2.7.11.22	0.539
2fvd	LIA	Cyclin-dependent kinase 2	2.7.11.22	0.539
4ek8	16K	Cyclin-dependent kinase 2	2.7.11.22	0.538
4fkt	48K	Cyclin-dependent kinase 2	2.7.11.22	0.537
3rak	03Z	Cyclin-dependent kinase 2	2.7.11.22	0.536
2r3r	6SC	Cyclin-dependent kinase 2	2.7.11.22	0.533
3r73	X87	Cyclin-dependent kinase 2	2.7.11.22	0.533
2w05	FRT	Cyclin-dependent kinase 2	2.7.11.22	0.530
4fkr	45K	Cyclin-dependent kinase 2	2.7.11.22	0.530
2r3m	SCX	Cyclin-dependent kinase 2	2.7.11.22	0.528
3qtu	X44	Cyclin-dependent kinase 2	2.7.11.22	0.528
3sw7	19K	Cyclin-dependent kinase 2	2.7.11.22	0.528
3r9d	X6B	Cyclin-dependent kinase 2	2.7.11.22	0.523
3s1h	56Z	Cyclin-dependent kinase 2	2.7.11.22	0.523
2r3l	SCW	Cyclin-dependent kinase 2	2.7.11.22	0.522
3qxp	X64	Cyclin-dependent kinase 2	2.7.11.22	0.522
2r3j	SCJ	Cyclin-dependent kinase 2	2.7.11.22	0.518
2r3o	2SC	Cyclin-dependent kinase 2	2.7.11.22	0.518
4acm	7YG	Cyclin-dependent kinase 2	2.7.11.22	0.516
4bgh	3I6	Cyclin-dependent kinase 2	2.7.11.22	0.516
3rmf	20Z	Cyclin-dependent kinase 2	2.7.11.22	0.514
3qtx	X43	Cyclin-dependent kinase 2	2.7.11.22	0.511
1p2a	5BN	Cyclin-dependent kinase 2	2.7.11.22	0.510
2r3k	SCQ	Cyclin-dependent kinase 2	2.7.11.22	0.509
1ykr	628	Cyclin-dependent kinase 2	2.7.11.22	0.507
3ral	04Z	Cyclin-dependent kinase 2	2.7.11.22	0.507
1y8y	CT7	Cyclin-dependent kinase 2	2.7.11.22	0.506
2c6m	DT5	Cyclin-dependent kinase 2	2.7.11.22	0.506
3sw4	18K	Cyclin-dependent kinase 2	2.7.11.22	0.505
1pxm	CK5	Cyclin-dependent kinase 2	2.7.11.22	0.501
2btr	U73	Cyclin-dependent kinase 2	2.7.11.22	0.501
2w17	I19	Cyclin-dependent kinase 2	2.7.11.22	0.500
1oit	HDT	Cyclin-dependent kinase 2	2.7.11.22	0.499
2uzn	C96	Cyclin-dependent kinase 2	2.7.11.22	0.499
4fko	20K	Cyclin-dependent kinase 2	2.7.11.22	0.498
4fkq	42K	Cyclin-dependent kinase 2	2.7.11.22	0.498
3rm7	19Z	Cyclin-dependent kinase 2	2.7.11.22	0.497
3r8v	Z62	Cyclin-dependent kinase 2	2.7.11.22	0.495
4fkw	62K	Cyclin-dependent kinase 2	2.7.11.22	0.495
2c6o	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.492
2vts	LZC	Cyclin-dependent kinase 2	2.7.11.22	0.492
2xmy	CDK	Cyclin-dependent kinase 2	2.7.11.22	0.492
2r3g	SC9	Cyclin-dependent kinase 2	2.7.11.22	0.491
3rah	O1Z	Cyclin-dependent kinase 2	2.7.11.22	0.491
3qxo	X65	Cyclin-dependent kinase 2	2.7.11.22	0.490
2b52	D42	Cyclin-dependent kinase 2	2.7.11.22	0.489
3qts	X46	Cyclin-dependent kinase 2	2.7.11.22	0.489
1y91	CT9	Cyclin-dependent kinase 2	2.7.11.22	0.488
1urw	I1P	Cyclin-dependent kinase 2	2.7.11.22	0.487
4fkv	61K	Cyclin-dependent kinase 2	2.7.11.22	0.486
3r9n	Z68	Cyclin-dependent kinase 2	2.7.11.22	0.485
4fx3	60K	Cyclin-dependent kinase 2	2.7.11.22	0.483
2uzo	C62	Cyclin-dependent kinase 2	2.7.11.22	0.482
2c69	CT8	Cyclin-dependent kinase 2	2.7.11.22	0.481
2vtp	LZ9	Cyclin-dependent kinase 2	2.7.11.22	0.481
1fvv	107	Cyclin-dependent kinase 2	2.7.11.22	0.480
2a0c	CK9	Cyclin-dependent kinase 2	2.7.11.22	0.479
3r8u	Z31	Cyclin-dependent kinase 2	2.7.11.22	0.479
3qqh	X0A	Cyclin-dependent kinase 2	2.7.11.22	0.478
3r1y	X76	Cyclin-dependent kinase 2	2.7.11.22	0.478
3s00	Z60	Cyclin-dependent kinase 2	2.7.11.22	0.478
1ke5	LS1	Cyclin-dependent kinase 2	2.7.11.22	0.476
2wih	P48	Cyclin-dependent kinase 2	2.7.11.22	0.476
3r7y	Z04	Cyclin-dependent kinase 2	2.7.11.22	0.476
3s2p	PMU	Cyclin-dependent kinase 2	2.7.11.22	0.476
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.475
3r1s	X73	Cyclin-dependent kinase 2	2.7.11.22	0.475
1gih	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.474
3qtz	X42	Cyclin-dependent kinase 2	2.7.11.22	0.474
3qu0	X40	Cyclin-dependent kinase 2	2.7.11.22	0.474
3ezr	EZR	Cyclin-dependent kinase 2	2.7.11.22	0.473
3rai	X85	Cyclin-dependent kinase 2	2.7.11.22	0.473
2c6k	DT2	Cyclin-dependent kinase 2	2.7.11.22	0.472
3qtr	X36	Cyclin-dependent kinase 2	2.7.11.22	0.472
3qx2	X63	Cyclin-dependent kinase 2	2.7.11.22	0.471
3rjc	06Z	Cyclin-dependent kinase 2	2.7.11.22	0.469
3rni	21Z	Cyclin-dependent kinase 2	2.7.11.22	0.469
3qzh	X69	Cyclin-dependent kinase 2	2.7.11.22	0.468
3r9h	Z67	Cyclin-dependent kinase 2	2.7.11.22	0.467
2j9m	PY8	Cyclin-dependent kinase 2	2.7.11.22	0.466
3r7v	Z02	Cyclin-dependent kinase 2	2.7.11.22	0.466
3r8l	Z30	Cyclin-dependent kinase 2	2.7.11.22	0.466
1ke6	LS2	Cyclin-dependent kinase 2	2.7.11.22	0.465
3igg	EFQ	Cyclin-dependent kinase 2	2.7.11.22	0.465
3unk	0BY	Cyclin-dependent kinase 2	2.7.11.22	0.465
2vto	LZ8	Cyclin-dependent kinase 2	2.7.11.22	0.464
4btj	ATP	Tau-tubulin kinase 1	2.7.11.1	0.464
4fkp	LS5	Cyclin-dependent kinase 2	2.7.11.22	0.463
2vv9	IM9	Cyclin-dependent kinase 2	2.7.11.22	0.461
3qwj	X6A	Cyclin-dependent kinase 2	2.7.11.22	0.461
3sqq	99Z	Cyclin-dependent kinase 2	2.7.11.22	0.461
1oiq	HDU	Cyclin-dependent kinase 2	2.7.11.22	0.460
2vtj	LZ4	Cyclin-dependent kinase 2	2.7.11.22	0.460
3qzf	X66	Cyclin-dependent kinase 2	2.7.11.22	0.460
1v1k	3FP	Cyclin-dependent kinase 2	2.7.11.22	0.459
3roy	22Z	Cyclin-dependent kinase 2	2.7.11.22	0.458
1oiy	N41	Cyclin-dependent kinase 2	2.7.11.22	0.457
3pj8	404	Cyclin-dependent kinase 2	2.7.11.22	0.457
1h0w	207	Cyclin-dependent kinase 2	2.7.11.22	0.456
2iw8	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.456
3rk9	09Z	Cyclin-dependent kinase 2	2.7.11.22	0.456
2vu3	LZE	Cyclin-dependent kinase 2	2.7.11.22	0.455
1gii	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.454
1g5s	I17	Cyclin-dependent kinase 2	2.7.11.22	0.453
2vtt	LZD	Cyclin-dependent kinase 2	2.7.11.22	0.453
1h0v	UN4	Cyclin-dependent kinase 2	2.7.11.22	0.452
3lfn	A27	Cyclin-dependent kinase 2	2.7.11.22	0.452
1pxp	CK8	Cyclin-dependent kinase 2	2.7.11.22	0.451
2r64	740	Cyclin-dependent kinase 2	2.7.11.22	0.451
4kd1	1QK	Cyclin-dependent kinase 2	2.7.11.22	0.451
2wxv	WXV	Cyclin-dependent kinase 2	2.7.11.22	0.448
3unj	0BX	Cyclin-dependent kinase 2	2.7.11.22	0.448
1pxj	CK2	Cyclin-dependent kinase 2	2.7.11.22	0.447
3qqf	X07	Cyclin-dependent kinase 2	2.7.11.22	0.447
3qql	X03	Cyclin-dependent kinase 2	2.7.11.22	0.447
2b54	D05	Cyclin-dependent kinase 2	2.7.11.22	0.446
3lfq	A28	Cyclin-dependent kinase 2	2.7.11.22	0.446
3qqk	X02	Cyclin-dependent kinase 2	2.7.11.22	0.446
4fkl	CK2	Cyclin-dependent kinase 2	2.7.11.22	0.446
2bts	U32	Cyclin-dependent kinase 2	2.7.11.22	0.445
3r7u	X96	Cyclin-dependent kinase 2	2.7.11.22	0.445
3qru	X19	Cyclin-dependent kinase 2	2.7.11.22	0.443
4qmp	DKI	Serine/threonine-protein kinase 24	2.7.11.1	0.443
1w0x	OLO	Cyclin-dependent kinase 2	2.7.11.22	0.442
3r83	Z14	Cyclin-dependent kinase 2	2.7.11.22	0.442