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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2c6c24IGlutamate carboxypeptidase 23.4.17.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2c6c24IGlutamate carboxypeptidase 23.4.17.211.000
2xejOKDGlutamate carboxypeptidase 23.4.17.210.550
2xegCI9Glutamate carboxypeptidase 23.4.17.210.526
2xefAR8Glutamate carboxypeptidase 23.4.17.210.499
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.456