sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2c42 | TPP | Pyruvate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2c42 | TPP | Pyruvate synthase | / | 1.000 | |
| 2pda | TPP | Pyruvate synthase | / | 0.657 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.644 | |
| 2uza | HTL | Pyruvate synthase | / | 0.625 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.624 | |
| 1kek | HTL | Pyruvate synthase | / | 0.592 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.559 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.507 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.474 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 4y1b | NAP | AntE | / | 0.463 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.461 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.458 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha | / | 0.458 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit beta | / | 0.458 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.452 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.451 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.442 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.442 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 |