sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 1.000 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.542 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.506 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.496 | |
| 3sjz | GNP | Translation initiation factor 2 subunit gamma | / | 0.496 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.495 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.493 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.492 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.492 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.490 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.487 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.486 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.486 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.486 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.484 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.484 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.484 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.483 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.482 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.481 | |
| 1tys | DHF | Thymidylate synthase | / | 0.479 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.479 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.478 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.478 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.478 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.477 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.477 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.477 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.477 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.477 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.476 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.476 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.476 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.476 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.476 | |
| 1zdw | FLV | Prenyltransferase | / | 0.475 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.475 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.475 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.475 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.475 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.474 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.474 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.474 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.473 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.473 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.473 | |
| 3qcz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.473 | |
| 3ruv | ANP | Chaperonin | / | 0.473 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.473 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.472 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.472 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.472 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.472 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.470 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.470 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.470 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.469 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.469 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.469 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.469 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.469 | |
| 3unj | 0BX | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.469 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.468 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.468 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.467 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.467 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.467 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.467 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.466 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.465 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.465 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.465 | |
| 2np7 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.465 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.465 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.465 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.465 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.465 | |
| 4i5h | G17 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.465 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.465 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.464 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.464 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.464 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.464 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.464 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.463 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.463 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.463 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.463 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.462 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.462 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.462 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.462 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.462 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.462 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.462 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.462 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.462 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.461 | |
| 3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.461 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.461 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.461 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.461 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.461 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.461 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.461 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.460 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.460 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.460 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.460 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.459 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.459 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.459 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.459 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.459 | |
| 1tf7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.458 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.458 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.458 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.458 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.458 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.458 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.458 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.458 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.457 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.457 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.457 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.456 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.456 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.456 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.456 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.456 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.456 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.456 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.456 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.456 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.456 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.456 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.456 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.456 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.455 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 1u9i | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.455 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.455 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.455 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.455 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.455 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.455 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.455 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.455 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.455 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.455 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.455 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.455 | |
| 5dp2 | NAP | CurF | / | 0.455 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.454 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2go4 | TUX | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.454 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.454 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.453 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.453 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.453 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.453 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.453 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.453 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.453 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3up3 | XCA | aceDAF-12 | / | 0.453 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.453 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.453 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.453 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.453 | |
| 4jl6 | ADP | Adenylate kinase | / | 0.453 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 5a3b | APR | SIR2 family protein | / | 0.453 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.453 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.452 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.452 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.452 | |
| 3cvu | FAD | RE11660p | / | 0.452 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.452 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.452 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.451 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2r3o | 2SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.451 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.451 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.451 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.451 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.451 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.450 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.450 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.450 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.450 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.450 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.450 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3rjc | 06Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.450 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.450 | |
| 4bi0 | Z0W | Dual specificity protein kinase TTK | 2.7.12.1 | 0.450 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.449 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.449 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.449 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.449 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.449 | |
| 3zk6 | H1I | Bcl-2-like protein 1 | / | 0.449 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.449 | |
| 4l2z | S7M | S-adenosylmethionine synthase | / | 0.449 | |
| 4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.449 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.449 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.448 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.448 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.448 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.448 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3bhr | THG | Thymidylate synthase | / | 0.448 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.448 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.448 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.447 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.447 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.447 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.447 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.447 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.447 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.447 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.447 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.447 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1c6z | ROC | Protease | / | 0.446 | |
| 1ppj | ANY | Cytochrome b | / | 0.446 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.446 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.446 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.446 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.446 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 3rus | ADP | Chaperonin | / | 0.446 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.446 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.446 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.446 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.446 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.446 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.446 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.445 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.445 | |
| 1t57 | FMN | Conserved protein | / | 0.445 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.445 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.445 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.445 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.445 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.445 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.445 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.445 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.445 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.445 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.445 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.444 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.444 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.444 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.444 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2y5k | YCU | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.444 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.444 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 4b74 | 1LH | Genome polyprotein | 3.4.21.98 | 0.444 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.444 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2fhk | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.443 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.443 | |
| 2v5z | SAG | Amine oxidase [flavin-containing] B | 1.4.3.4 | 0.443 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.443 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.443 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.443 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.443 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.443 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.443 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.443 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.442 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.442 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.442 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.442 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.442 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.442 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.442 | |
| 3b9l | AZZ | Serum albumin | / | 0.442 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.442 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4hjf | C2E | GGDEF family protein | / | 0.442 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.442 | |
| 4jlo | ADP | Adenylate kinase | / | 0.442 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.442 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.442 | |
| 4phl | PIL | Phosphodiesterase | / | 0.442 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 4ztv | TA7 | Anthranilate phosphoribosyltransferase | / | 0.442 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.442 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.441 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.441 | |
| 1ke8 | LS4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1u3v | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.441 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3bpz | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.441 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.441 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.441 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3liq | E14 | Protease | / | 0.441 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.441 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.441 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.441 | |
| 4jky | ADP | Adenylate kinase | / | 0.441 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.440 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2o3z | AI7 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.440 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.440 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.440 | |
| 3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3t19 | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.440 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.440 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.440 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.440 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.440 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.440 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 5cae | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.440 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.440 |