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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.31.000
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.684
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.679
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.663
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.654
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.652
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.650
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.645
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.643
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.637
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.633
3qly55VUncharacterized protein/0.628
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.623
4h9506UDihydrofolate reductase1.5.1.30.621
1klkPMDDihydrofolate reductase1.5.1.30.620
1hfpMOTDihydrofolate reductase1.5.1.30.619
1hfqMOTDihydrofolate reductase1.5.1.30.617
1aoeGW3Dihydrofolate reductase1.5.1.30.616
3qlrQLRDihydrofolate reductase1.5.1.30.615
3cseN22Uncharacterized protein/0.613
4h9614QDihydrofolate reductase1.5.1.30.613
1bozPRDDihydrofolate reductase1.5.1.30.611
4h9753SDihydrofolate reductase1.5.1.30.610
4ixeIXEDihydrofolate reductase1.5.1.30.609
1ia1TQ3Dihydrofolate reductase1.5.1.30.608
1m78CLZDihydrofolate reductase1.5.1.30.607
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.604
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.604
3qls55VDihydrofolate reductase1.5.1.30.604
1dg5TOPDihydrofolate reductase1.5.1.30.603
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.601
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.601
4kfj1R0Dihydrofolate reductase1.5.1.30.597
1cd2FOLDihydrofolate reductase1.5.1.30.596
1rx3MTXDihydrofolate reductase1.5.1.30.594
2cd2FOLDihydrofolate reductase1.5.1.30.593
4kd79DRDihydrofolate reductase1.5.1.30.592
3qlzQLZUncharacterized protein/0.591
1e26GPBDihydrofolate reductase1.5.1.30.590
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.589
2fziDH3Dihydrofolate reductase1.5.1.30.587
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.585
4h9814QUncharacterized protein/0.585
2w3aTOPDihydrofolate reductase1.5.1.30.583
3eem53VUncharacterized protein/0.579
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.578
3ql3FOLDihydrofolate reductase1.5.1.30.578
4m6l21VDihydrofolate reductase1.5.1.30.577
1dajMOTDihydrofolate reductase1.5.1.30.576
1vj3TABDihydrofolate reductase1.5.1.30.574
2fzhDH1Dihydrofolate reductase1.5.1.30.574
4g8zTOPDihydrofolate reductase1.5.1.30.574
3td8D2RDihydrofolate reductase1.5.1.30.573
1m7aMQUDihydrofolate reductase1.5.1.30.571
5cccDDFDihydrofolate reductase1.5.1.30.569
3eej53RUncharacterized protein/0.568
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.567
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.566
4xe606UDihydrofolate reductase1.5.1.30.566
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.565
3qlxQLRUncharacterized protein/0.564
3sa16DRDihydrofolate reductase/0.564
3eek53SUncharacterized protein/0.563
3qlwN22Dihydrofolate reductase1.5.1.30.563
1m79MQ1Dihydrofolate reductase1.5.1.30.561
2zzaFOLDihydrofolate reductase/0.561
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.560
3k47D09Dihydrofolate reductase1.5.1.30.560
4ixgIXGDihydrofolate reductase1.5.1.30.560
4x5fFOLDihydrofolate reductase1.5.1.30.559
3eigMTXDihydrofolate reductase1.5.1.30.556
2w3vTOPDihydrofolate reductase/0.554
3tq9MTXDihydrofolate reductase/0.554
3nxoD2BDihydrofolate reductase1.5.1.30.553
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.553
4m2xTMQDihydrofolate reductase1.5.1.30.553
4p68MTXDihydrofolate reductase/0.553
7dfrFOLDihydrofolate reductase1.5.1.30.552
1ia2TQ4Dihydrofolate reductase1.5.1.30.551
1ia3TQ5Dihydrofolate reductase1.5.1.30.551
1s3yTQTDihydrofolate reductase1.5.1.30.551
1dg7WRBDihydrofolate reductase1.5.1.30.549
3nxtD2EDihydrofolate reductase1.5.1.30.549
3l3rOAGDihydrofolate reductase1.5.1.30.548
3tqbFOLDihydrofolate reductase/0.548
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.544
4kak06UDihydrofolate reductase1.5.1.30.544
4p66MTXDihydrofolate reductase/0.544
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.543
4nx7FOLDihydrofolate reductase1.5.1.30.543
4nx6FOLDihydrofolate reductase1.5.1.30.542
3cd2MTXDihydrofolate reductase1.5.1.30.541
3sh25DRDihydrofolate reductase1.5.1.30.541
4kne1CYDihydrofolate reductase1.5.1.30.541
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.540
3nxyD2HDihydrofolate reductase1.5.1.30.539
3sai9DRDihydrofolate reductase/0.538
2w3wVG9Dihydrofolate reductase/0.537
4ddrMMVDihydrofolate reductase1.5.1.30.537
4x5gFOLDihydrofolate reductase1.5.1.30.537
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.535
4ixfIXFDihydrofolate reductase1.5.1.30.535
1ddrMTXDihydrofolate reductase1.5.1.30.534
3jwcEKBDihydrofolate reductase/0.534
3jwm5WBDihydrofolate reductase/0.534
3oafOAGDihydrofolate reductase1.5.1.30.532
3ntz3TZDihydrofolate reductase1.5.1.30.531
1df7MTXDihydrofolate reductase1.5.1.30.530
2fzjDH3Dihydrofolate reductase1.5.1.30.529
3srwQ27Dihydrofolate reductase1.5.1.30.529
3r336MEDihydrofolate reductase1.5.1.30.528
3srsM23Dihydrofolate reductase1.5.1.30.528
1ddsMTXDihydrofolate reductase1.5.1.30.527
1ly3COGDihydrofolate reductase1.5.1.30.527
1u72MTXDihydrofolate reductase1.5.1.30.527
3fywXCFDihydrofolate reductase1.5.1.30.527
3dfrMTXDihydrofolate reductase1.5.1.30.526
3sgy06WDihydrofolate reductase1.5.1.30.526
1tdrMTXDihydrofolate reductase1.5.1.30.525
3srqQ19Dihydrofolate reductase1.5.1.30.525
1ia4TQ6Dihydrofolate reductase1.5.1.30.524
3sa27DRDihydrofolate reductase/0.524
1s3wTQTDihydrofolate reductase1.5.1.30.523
4cd2FOLDihydrofolate reductase1.5.1.30.523
1mvsDTMDihydrofolate reductase1.5.1.30.522
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.522
3sqyQ11Dihydrofolate reductase1.5.1.30.522
1rx5DDFDihydrofolate reductase1.5.1.30.521
2w3mFOLDihydrofolate reductase1.5.1.30.519
3nxrD2DDihydrofolate reductase1.5.1.30.519
3tq8TOPDihydrofolate reductase/0.519
3eel53TUncharacterized protein/0.518
3s3vTOPDihydrofolate reductase1.5.1.30.518
4cdmFO1Deoxyribodipyrimidine photolyase/0.518
3ix9MTXDihydrofolate reductase1.5.1.30.517
4fgg0U5Dihydrofolate reductase1.5.1.30.517
1rb3MTXDihydrofolate reductase1.5.1.30.516
1rd7FOLDihydrofolate reductase1.5.1.30.516
2cig1DGDihydrofolate reductase1.5.1.30.516
2uxoTACHTH-type transcriptional regulator TtgR/0.516
4x5hFOLDihydrofolate reductase1.5.1.30.516
4kbn25UDihydrofolate reductase1.5.1.30.515
4x5jFOLDihydrofolate reductase1.5.1.30.515
1hfrMOTDihydrofolate reductase1.5.1.30.514
1s3vTQDDihydrofolate reductase1.5.1.30.514
1kmsLIHDihydrofolate reductase1.5.1.30.513
4kjjFOLDihydrofolate reductase1.5.1.30.513
1zky689Estrogen receptor/0.512
3sruQ26Dihydrofolate reductase1.5.1.30.512
2jfaRALEstrogen receptor/0.511
3i8aN22Dihydrofolate reductase1.5.1.30.511
3och2MXDihydrofolate reductase1.5.1.30.511
3dauMTXDihydrofolate reductase1.5.1.30.510
4fhbFOLDihydrofolate reductase1.5.1.30.510
3ia4MTXDihydrofolate reductase/0.509
3lnbCOAN-acetyltransferase family protein/0.509
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.509
1kl2FONSerine hydroxymethyltransferase/0.508
3ghwGHWDihydrofolate reductase1.5.1.30.508
1pd8CO4Dihydrofolate reductase1.5.1.30.507
1rx2FOLDihydrofolate reductase1.5.1.30.507
1rx7FOLDihydrofolate reductase1.5.1.30.507
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.507
4kebFOLDihydrofolate reductase1.5.1.30.507
4g95OAGDihydrofolate reductase1.5.1.30.506
1ra2FOLDihydrofolate reductase1.5.1.30.505
1xp9AIJEstrogen receptor/0.505
1xpcAITEstrogen receptor/0.505
2b1z17MEstrogen receptor/0.505
2fszOHTEstrogen receptor beta/0.505
2jedLG8Protein kinase C theta type2.7.11.130.505
4i13FOLDihydrofolate reductase1.5.1.30.505
3p3zP3ZPutative cytochrome P450/0.504
3frfXCFDihydrofolate reductase1.5.1.30.503
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.503
4j6dTESCytochrome P450 monooxygenase/0.503
1dr4HBIDihydrofolate reductase1.5.1.30.502
1rh3MTXDihydrofolate reductase1.5.1.30.502
1rx6DDFDihydrofolate reductase1.5.1.30.502
2ocfESTEstrogen receptor/0.502
3cv9VDXVitamin D3 dihydroxylase/0.502
3zoiM2WIsopenicillin N synthase1.21.3.10.502
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.502
1re7FOLDihydrofolate reductase1.5.1.30.501
2drcMTXDihydrofolate reductase1.5.1.30.501
2uxhQUEHTH-type transcriptional regulator TtgR/0.501
3a1l2CCCytochrome P450/0.501
3nxvD2FDihydrofolate reductase1.5.1.30.501
2cmoM1LGlutamate receptor 2/0.500
3d80Q22Dihydrofolate reductase1.5.1.30.500
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.500
3srrQ20Dihydrofolate reductase1.5.1.30.500
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.500
4m6kFOLDihydrofolate reductase1.5.1.30.500
4x5iFOLDihydrofolate reductase1.5.1.30.500
1dr3HBIDihydrofolate reductase1.5.1.30.499
1dyrTOPDihydrofolate reductase1.5.1.30.499
1s3uTQDDihydrofolate reductase1.5.1.30.499
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.499
4ej1FOLDihydrofolate reductase1.5.1.30.499
1l2jETCEstrogen receptor beta/0.498
1pd9CO4Dihydrofolate reductase1.5.1.30.498
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
3datMTXDihydrofolate reductase/0.498
3n0hTOPDihydrofolate reductase1.5.1.30.498
1rf7DHFDihydrofolate reductase1.5.1.30.497
2dhfDZFDihydrofolate reductase1.5.1.30.497
3fraI2HDihydrofolate reductase1.5.1.30.497
3freTOPDihydrofolate reductase1.5.1.30.497
3lamKRPGag-Pol polyprotein2.7.7.490.497
3q95ESLEstrogen receptor/0.497
3zkyWT4Isopenicillin N synthase1.21.3.10.497
1oc1ASVIsopenicillin N synthase1.21.3.10.496
3nj0PYVAbscisic acid receptor PYL2/0.496
3ov4EQUSteroid Delta-isomerase5.3.3.10.496
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.496
4fgh0U6Dihydrofolate reductase1.5.1.30.496
1bzfTMQDihydrofolate reductase1.5.1.30.494
3njoPYVAbscisic acid receptor PYR1/0.494
4j6bPLOCytochrome P450 monooxygenase/0.494
4qa1B3NHistone deacetylase 83.5.1.980.494
1dyhDZFDihydrofolate reductase1.5.1.30.493
1ohjCOPDihydrofolate reductase1.5.1.30.493
1xp6AIUEstrogen receptor/0.493
4j6cSTRCytochrome P450 monooxygenase/0.493
1bk0ACVIsopenicillin N synthase1.21.3.10.492
1draMTXDihydrofolate reductase1.5.1.30.492
1gwqZTWEstrogen receptor/0.492
1x7e244Estrogen receptor/0.492
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
2qgtEEDEstrogen receptor/0.492
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.492
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.491
2p15EZTEstrogen receptor/0.491
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.491
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.491
1dhfFOLDihydrofolate reductase1.5.1.30.490
1z6tADPApoptotic protease-activating factor 1/0.490
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.490
3frdDHFDihydrofolate reductase1.5.1.30.490
2bf7HBIPteridine reductase 11.5.1.330.489
2g44T3OEstrogen receptor/0.489
3drcMTXDihydrofolate reductase1.5.1.30.489
3l034OHEstrogen receptor/0.489
3olsESTEstrogen receptor beta/0.489
4dfrMTXDihydrofolate reductase1.5.1.30.489
4e0u0MVCyclic dipeptide N-prenyltransferase/0.489
4j24ESTEstrogen receptor beta/0.489
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.489
1lhwESMSex hormone-binding globulin/0.488
1qknRALEstrogen receptor beta/0.488
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
3l8sBFFMitogen-activated protein kinase 14/0.488
4a9mP9MBromodomain-containing protein 2/0.488
1l2iETCEstrogen receptor/0.487
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.487
1uzwCDHIsopenicillin N synthase1.21.3.10.487
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.487
2xtbKRMAdenosine kinase, putative/0.487
2yatEEUEstrogen receptor/0.487
3jw5TOPDihydrofolate reductase/0.487
3qyoQ24Dihydrofolate reductase1.5.1.30.487
4elb34RDihydrofolate reductase/0.487
4p6wMOFGlucocorticoid receptor/0.487
2jb4A14Isopenicillin N synthase1.21.3.10.486
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.486
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.486
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.486
3gyf51PDihydrofolate reductase1.5.1.30.486
3ollESTEstrogen receptor beta/0.486
1fmjRTLRetinol dehydratase/0.485
1gwrESTEstrogen receptor/0.485
1hb3SCVIsopenicillin N synthase1.21.3.10.485
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.485
2vcmM11Isopenicillin N synthase1.21.3.10.485
4bb3KKAIsopenicillin N synthase1.21.3.10.485
4kfjFOLDihydrofolate reductase1.5.1.30.485
5bt42LOBromodomain-containing protein 4/0.485
2wo7ASVIsopenicillin N synthase1.21.3.10.484
3c3dFO12-phospho-L-lactate transferase/0.484
1ao8MTXDihydrofolate reductase1.5.1.30.483
1dreMTXDihydrofolate reductase1.5.1.30.483
1kijNOVDNA gyrase subunit B/0.483
1ra8FOLDihydrofolate reductase1.5.1.30.483
2l98STLTroponin C, slow skeletal and cardiac muscles/0.483
4qa0SHHHistone deacetylase 83.5.1.980.483
1rf9DBRCamphor 5-monooxygenase1.14.15.10.482
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
2ejzSAHDiphthine synthase/0.482
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.482
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.482
3a4pDFQHepatocyte growth factor receptor2.7.10.10.482
3l6jZ90Alr2278 protein/0.482
4i1nFOLDihydrofolate reductase1.5.1.30.482
4j26ESTEstrogen receptor beta/0.482
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.482
5hi6MTXDihydrofolate reductase/0.482
2q7gCCLPyrrolysine--tRNA ligase/0.481
4iv21GREstrogen receptor/0.481
4qjcIXEDihydrofolate reductase1.5.1.30.481
1jomFFODihydrofolate reductase1.5.1.30.480
1ludTRRDihydrofolate reductase1.5.1.30.480
1ly4COQDihydrofolate reductase1.5.1.30.480
2iviACWIsopenicillin N synthase1.21.3.10.480
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.480
3lfcZ86Mitogen-activated protein kinase 14/0.480
3q9bB3NAcetylpolyamine amidohydrolase/0.480
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.480
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
1qiqACCIsopenicillin N synthase1.21.3.10.479
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2f6rACOBifunctional coenzyme A synthase/0.479
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.479
2z2w770Wee1-like protein kinase2.7.10.20.479
3gcq1BUMitogen-activated protein kinase 14/0.479
3njoP2MAbscisic acid receptor PYR1/0.479
3nmpPYVAbscisic acid receptor PYL2/0.479
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.479
4xoqF42Coenzyme F420:L-glutamate ligase/0.479
5k2cZMAAdenosine receptor A2a/0.479
1lhoAOMSex hormone-binding globulin/0.478
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.478
3abaFLICytochrome P450/0.478
3fy8XCFDihydrofolate reductase1.5.1.30.478
3fyvXCFDihydrofolate reductase1.5.1.30.478
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.478
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3nksACJProtoporphyrinogen oxidase1.3.3.40.478
3nr4PYVAbscisic acid receptor PYL2/0.478
5cc9DDFDihydrofolate reductase1.5.1.30.478
5dxgESTEstrogen receptor/0.478
1dyiFOLDihydrofolate reductase1.5.1.30.477
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
1ot7CHCBile acid receptor/0.477
4dsbA8SAbscisic acid receptor PYL3/0.477
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.477
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
1mvtDTMDihydrofolate reductase1.5.1.30.476
1ra3MTXDihydrofolate reductase1.5.1.30.476
2w9hTOPDihydrofolate reductase1.5.1.30.476
3c1xCKKHepatocyte growth factor receptor2.7.10.10.476
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.476
3qm4PN0Cytochrome P450 2D6/0.476
3tk3CPZCytochrome P450 2B41.14.14.10.476
4c3yANB3-ketosteroid dehydrogenase/0.476
4egnTWOCytochrome P450/0.476
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.476
4lgaA2OAbscisic acid receptor PYL2/0.476
4lsjLSJGlucocorticoid receptor/0.476
4pxmESTEstrogen receptor/0.476
4qa2SHHHistone deacetylase 83.5.1.980.476
1e7qNAPGDP-L-fucose synthase/0.475
1rb2FOLDihydrofolate reductase1.5.1.30.475
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.475
1u71MXADihydrofolate reductase1.5.1.30.475
1upw444Oxysterols receptor LXR-beta/0.475
2g5oDRQEstrogen receptor/0.475
2ph5NADHomospermidine synthase/0.475
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.475
3ghvGHCDihydrofolate reductase1.5.1.30.475
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
3ns2PYVAbscisic acid receptor PYL2/0.475
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.475
5fd8A5APutative carboxypeptidase yocD/0.475
5k2aZMAAdenosine receptor A2a/0.475
1b2lNDCAlcohol dehydrogenase1.1.1.10.474
1drfFOLDihydrofolate reductase1.5.1.30.474
1ewyFADFerredoxin--NADP reductase1.18.1.20.474
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.474
1og5SWFCytochrome P450 2C9/0.474
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.474
2cleF6FTryptophan synthase alpha chain/0.474
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.474
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.474
3pllF06Endothiapepsin3.4.23.220.474
3s7a684Dihydrofolate reductase1.5.1.30.474
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
3wsbRWZFarnesyltransferase, putative/0.474
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
4elb34SDihydrofolate reductase/0.474
4ele31IDihydrofolate reductase/0.474
4iw61GUEstrogen receptor/0.474
4jbtASDCytochrome P450 monooxygenase/0.474
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.474
3uzaT4GAdenosine receptor A2a/0.474
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.473
1hb1OCVIsopenicillin N synthase1.21.3.10.473
1krv147Galactoside O-acetyltransferase2.3.1.180.473
1xddAAYIntegrin alpha-L/0.473
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.473
2q70DC8Estrogen receptor/0.473
3b9lAZZSerum albumin/0.473
3gi2GHWDihydrofolate reductase1.5.1.30.473
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
4jdaA9SAbscisic acid receptor PYL3/0.473
1ohkCOPDihydrofolate reductase1.5.1.30.472
1vzdCB3Thymidylate synthase/0.472
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
4jlm1NNDeoxycytidine kinase2.7.1.740.472
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.471
1blzACVIsopenicillin N synthase1.21.3.10.471
1m9k7NINitric oxide synthase, endothelial1.14.13.390.471
1n8wCOAMalate synthase G/0.471
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
1r9oFLPCytochrome P450 2C9/0.471
1rd4L08Integrin alpha-L/0.471
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.471
1ysx4EBSerum albumin/0.471
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.471
2rehFADNitroalkane oxidase1.7.3.10.471
2yjaESTEstrogen receptor/0.471
2zbaZBATrichothecene 3-O-acetyltransferase/0.471
3a783EVVitamin D3 receptor/0.471
3ojiPYVAbscisic acid receptor PYL3/0.471
3qj5022Alcohol dehydrogenase class-31.1.1.10.471
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.471
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.471
3zy6GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.471
4d7eFADPutative lysine-N-oxygenase/0.471
4g1y0VOVitamin D3 receptor A/0.471
4h6rFDAProline dehydrogenase/0.471
4m7vRARDihydrofolate reductase/0.471
1pkfEPDEpothilone C/D epoxidase1.140.470
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.470
2giuFBREstrogen receptor beta/0.470
2nn7M29Carbonic anhydrase 14.2.1.10.470
3antS82Bifunctional epoxide hydrolase 23.3.2.100.470
3c3xNAPEugenol synthase 11.1.1.3180.470
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
3erdDESEstrogen receptor/0.470
3fl8RARDihydrofolate reductase/0.470
3uudESTEstrogen receptor/0.470
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.470
4mv1ADPBiotin carboxylase6.3.4.140.470
3reyXACAdenosine receptor A2a/0.470
1rc4DDFDihydrofolate reductase1.5.1.30.469
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.469
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
3htjETEbrA repressor/0.469
3mg3ECHOrange carotenoid-binding protein/0.469
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.469
3sr5Q12Dihydrofolate reductase1.5.1.30.469
3uvvREARetinoic acid receptor RXR-alpha/0.469
4wx2F6FTryptophan synthase alpha chain/0.469
4wx2F6FTryptophan synthase beta chain4.2.1.200.469
5bp9SAHPutative methyltransferase protein/0.469
1nceCB3Thymidylate synthase/0.468
1rx4DDFDihydrofolate reductase1.5.1.30.468
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.468
1x8lOXRRetinol dehydratase/0.468
2d0kFOLDihydrofolate reductase1.5.1.30.468
2uxiG50HTH-type transcriptional regulator TtgR/0.468
2x7hPFNProstaglandin reductase 310.468
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
4bmpFMNProtein NrdI/0.468
4dk70KSOxysterols receptor LXR-beta/0.468
4i9i1DYTankyrase-12.4.2.300.468
4y1bNAPAntE/0.468
1dhjMTXDihydrofolate reductase1.5.1.30.467
1kdmDHTSex hormone-binding globulin/0.467
1ove358Mitogen-activated protein kinase 14/0.467
1pq944BOxysterols receptor LXR-beta/0.467
1yimCM4Estrogen receptor/0.467
2pogWSTEstrogen receptor/0.467
2rtmIMIStreptavidin/0.467
2z97CAMCamphor 5-monooxygenase1.14.15.10.467
3ezpB3NHistone deacetylase 83.5.1.980.467
4bfuZVUPantothenate kinase2.7.1.330.467
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.467
4ea13RXDehydrosqualene synthase/0.467
4k9yK9YFocal adhesion kinase 12.7.10.20.467
4pkwGM6Lethal factor3.4.24.830.467
4uyf73BBromodomain-containing protein 2/0.467
1bwsNDPGDP-L-fucose synthase/0.466
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.466
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.466
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.466
3h3t16HCollagen type IV alpha-3-binding protein/0.466
3new3NEMitogen-activated protein kinase 14/0.466
3zkuHCVIsopenicillin N synthase1.21.3.10.466
4alhA9PBromodomain-containing protein 2/0.466
4at2ASDPossible succinate dehydrogenase/0.466
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.466
4l8u9AZSerum albumin/0.466
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.466
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.465
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
1yc2NADNAD-dependent protein deacylase 2/0.465
2rhrEMOPutative ketoacyl reductase1.3.10.465
2w4qCBWProstaglandin reductase 21.3.1.480.465
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
3h3r14HCollagen type IV alpha-3-binding protein/0.465
3hucG97Mitogen-activated protein kinase 14/0.465
3kpzZNEVitamin D3 receptor/0.465
3roeTHMNAD(P)H-hydrate epimerase5.1.99.60.465
3w0gW07Vitamin D3 receptor/0.465
3w0tHPULactoylglutathione lyase4.4.1.50.465
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.465
4bwaN0BPyrrolysine--tRNA ligase/0.465
4ce3L4VATP-dependent molecular chaperone HSP82/0.465
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.465
4hnc0UTMandelate racemase/0.465
4iteTEYVitamin D3 receptor/0.465
4iw8KN3Estrogen receptor/0.465
4jq2SUZAldo-keto reductase family 1 member C2/0.465
4v2gITCTetracycline repressor protein class D/0.465
4yswNAIXanthine dehydrogenase/oxidase/0.465
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.465
3emlZMAAdenosine receptor A2a/0.465
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.464
1cqp803Integrin alpha-L/0.464
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1jolFFODihydrofolate reductase1.5.1.30.464
1kzjCB3Thymidylate synthase/0.464
1q5dEPBEpothilone C/D epoxidase1.140.464
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
1zzlTZYMitogen-activated protein kinase 14/0.464
2ewaSB2Mitogen-activated protein kinase 14/0.464
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.464
3gc9B45Mitogen-activated protein kinase 112.7.11.240.464
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3m08RARDihydrofolate reductase1.5.1.30.464
3nu03TUDihydrofolate reductase1.5.1.30.464
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.464
4e37NDPCatalase1.11.1.60.464
4jlj1NMDeoxycytidine kinase2.7.1.740.464
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
1d2sDHTSex hormone-binding globulin/0.463
1dduCB3Thymidylate synthase/0.463
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.463
2y37A54Nitric oxide synthase, inducible1.14.13.390.463
3adaNADSubunit alpha of sarocosine oxidase/0.463
3c35KAIGlutamate receptor ionotropic, kainate 1/0.463
3d5wADPSerine/threonine-protein kinase PLK/0.463
3k4551PDihydrofolate reductase1.5.1.30.463
3l0lHC3Nuclear receptor ROR-gamma/0.463
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4bftZVTPantothenate kinase2.7.1.330.463
4bfxZVXPantothenate kinase2.7.1.330.463
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.463
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4h4o506Gag-Pol polyprotein2.7.7.490.463
4ivy1GTEstrogen receptor/0.463
4m4821BSodium-dependent dopamine transporter/0.463
5d1bTSNHistone deacetylase 83.5.1.980.463
5hyrESTEstrogen receptor/0.463
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
1fm4DXCMajor pollen allergen Bet v 1-L/0.462
1gnwGTXGlutathione S-transferase F22.5.1.180.462
1ml6GBXGlutathione S-transferase A22.5.1.180.462
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.462
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.462
2rqfJH3Hemolymph juvenile hormone binding protein/0.462
3e5aVX6Aurora kinase A2.7.11.10.462
3gncQQQGlutaryl-CoA dehydrogenase/0.462
3hv3R49Mitogen-activated protein kinase 14/0.462
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3vrwYS5Vitamin D3 receptor/0.462
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.462
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4i8vBHFCytochrome P450 1A11.14.14.10.462
4ict1EDMycocyclosin synthase1.14.21.90.462
4iwf15QEstrogen receptor/0.462
4l4aCAMCamphor 5-monooxygenase1.14.15.10.462
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.462
4zn7DESEstrogen receptor/0.462
1dyjDDFDihydrofolate reductase1.5.1.30.461
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.461
1o9bNAIQuinate/shikimate dehydrogenase/0.461
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1p93DEXGlucocorticoid receptor/0.461
1zg32HIIsoflavone 4'-O-methyltransferase/0.461
2j7yE3OEstrogen receptor beta/0.461
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.461
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.461
2vbdV10Isopenicillin N synthase1.21.3.10.461
3csdEMOPutative ketoacyl reductase1.3.10.461
3p9tTCLRepressor/0.461
3t3q9PLCytochrome P450 2A61.14.130.461
3tdaPN0Cytochrome P450 2D6/0.461
3up3XCAaceDAF-12/0.461
4hni16WCasein kinase I isoform epsilon2.7.11.10.461
4lg5A1OAbscisic acid receptor PYL2/0.461
4nm9FADBifunctional protein PutA/0.461
4xz3COAAcyl-CoA synthetase (NDP forming)/0.461
4zj8SUVOrexin receptor type 1/0.461
1dgfNDPCatalase1.11.1.60.460
1dhiMTXDihydrofolate reductase1.5.1.30.460
1e7aPFLSerum albumin/0.460
1nq7ARLNuclear receptor ROR-beta/0.460
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.460
1vrqFONSubunit alpha of sarocosine oxidase/0.460
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.460
2rabNADGlutathione amide reductase/0.460
2xvw9NRSerum albumin/0.460
3eai328Nitric oxide synthase, inducible1.14.13.390.460
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3irxUDRGag-Pol polyprotein2.7.7.490.460
3lakKR1Gag-Pol polyprotein2.7.7.490.460
3tfn2CJDehydrosqualene synthase/0.460
4ap1NAPSteroid monooxygenase/0.460
4cukNAID-lactate dehydrogenase/0.460
4g1z0VPVitamin D3 receptor A/0.460
1ezfIN0Squalene synthase2.5.1.210.459
1fmlRTLRetinol dehydratase/0.459
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.459
1n4hREANuclear receptor ROR-beta/0.459
1olmVTQSEC14-like protein 2/0.459
1p7tACOMalate synthase G/0.459
1pl6572Sorbitol dehydrogenase1.1.1.140.459
1qjfACSIsopenicillin N synthase1.21.3.10.459
1sr7MOFProgesterone receptor/0.459
1txtCAAHMG-CoA synthase/0.459
1w06W05Isopenicillin N synthase1.21.3.10.459
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
2ea4F79Methionine aminopeptidase 2/0.459
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.459
2rh9IGPTryptophan synthase alpha chain/0.459
2vn0TDZCytochrome P450 2C8/0.459
2w8y486Progesterone receptor/0.459
3bgrT27Gag-Pol polyprotein2.7.7.490.459
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3nefPYVAbscisic acid receptor PYL1/0.459
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.459
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3vtdTKDVitamin D3 receptor/0.459
4a9iP9IBromodomain-containing protein 2/0.459
4jlk1NODeoxycytidine kinase2.7.1.740.459
4lrrCF9Thymidylate synthase/0.459
5jtbZMAAdenosine receptor A2a/0.459
3uzcT4EAdenosine receptor A2a/0.459
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1g50ESTEstrogen receptor/0.458
1lhuESTSex hormone-binding globulin/0.458
1o6rR19Squalene--hopene cyclase4.2.1.1290.458
1synF89Thymidylate synthase/0.458
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.458
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.458
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2oaxSNLMineralocorticoid receptor/0.458
2ojg19AMitogen-activated protein kinase 12.7.11.240.458
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
3ad9NADSubunit alpha of sarocosine oxidase/0.458
3btjDEQHTH-type transcriptional regulator QacR/0.458
3fy9XCFDihydrofolate reductase1.5.1.30.458
3h3sH15Collagen type IV alpha-3-binding protein/0.458
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3vf60H6Glucokinase2.7.1.20.458
3vt7VDXVitamin D3 receptor/0.458
4bfvZVVPantothenate kinase2.7.1.330.458
4elg52JDihydrofolate reductase/0.458
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.458
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.457
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.457
1ep4S11Gag-Pol polyprotein2.7.7.490.457
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.457
1ppjANYCytochrome b/0.457
1wpgADPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.457
2a8sGTPU8 snoRNA-decapping enzyme/0.457
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.457
2y60M8FIsopenicillin N synthase1.21.3.10.457
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.457
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.457
3pldF90Endothiapepsin3.4.23.220.457
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.457
4dma0L8Estrogen receptor/0.457
4iah1DXAlr2278 protein/0.457
5dx3ESTEstrogen receptor/0.457
5hs1VORLanosterol 14-alpha demethylase/0.457
5irnADPNucleotide binding oligomerization domain containing 2/0.457
3qakUKAAdenosine receptor A2a/0.457
1c1bGCAGag-Pol polyprotein2.7.7.490.456
1dliUDXUDP-glucose 6-dehydrogenase/0.456
1fm69CRRetinoic acid receptor RXR-alpha/0.456
1kquBR4Phospholipase A2, membrane associated/0.456
1o5rFR9Adenosine deaminase3.5.4.40.456
1p0pBCHCholinesterase3.1.1.80.456
1rg7MTXDihydrofolate reductase1.5.1.30.456
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.456
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
1zydATPeIF-2-alpha kinase GCN2/0.456
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.456
2wjoQUDBeta-secretase 13.4.23.460.456
3h03UBPGlutamate receptor 2/0.456
3kdiA8SAbscisic acid receptor PYL2/0.456
3mdmFJZCholesterol 24-hydroxylase/0.456
4g090VDHistidinol dehydrogenase/0.456
4i421HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.456
4imw1EVNitric oxide synthase, brain1.14.13.390.456
5iu4ZMAAdenosine receptor A2a/0.456
1obnASVIsopenicillin N synthase1.21.3.10.455
1ot7IU5Bile acid receptor/0.455
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1yqj6NPMitogen-activated protein kinase 14/0.455
2apgFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.455
2bu9HFVIsopenicillin N synthase1.21.3.10.455
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
2fai459Estrogen receptor/0.455
2gv8NDPThiol-specific monooxygenase1.14.130.455
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2p1u4TNRetinoic acid receptor RXR-alpha/0.455
2qa8GENEstrogen receptor/0.455
2zd1T27Gag-Pol polyprotein2.7.7.490.455
3fnlSHALactoperoxidase/0.455
3fp0FP015-O-acetyltransferase/0.455
3itzP66Mitogen-activated protein kinase 14/0.455
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
3vjcZGASqualene synthase2.5.1.210.455
4ag7COAGlucosamine 6-phosphate N-acetyltransferase/0.455
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4dscA8SAbscisic acid receptor PYL3/0.455
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.455
4ia1BIVVitamin D3 receptor A/0.455
4nmbFADBifunctional protein PutA/0.455
5iw5NMNNADH pyrophosphatase/0.455
5iua6DXAdenosine receptor A2a/0.455
1e3kR18Progesterone receptor/0.454
1o6qR17Squalene--hopene cyclase4.2.1.1290.454
2ouzC3DEstrogen receptor/0.454
2owb626Serine/threonine-protein kinase PLK12.7.11.210.454
3ctj320Hepatocyte growth factor receptor2.7.10.10.454
3fwfCAMCamphor 5-monooxygenase1.14.15.10.454
3fwjCAMCamphor 5-monooxygenase1.14.15.10.454
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.454
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
3w6hAZMCarbonic anhydrase 14.2.1.10.454
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
3wnzADPAlanine--anticapsin ligase/0.454
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.454
4bfpSWYTankyrase-22.4.2.300.454
4ivw1GJEstrogen receptor/0.454
4l4cCAMCamphor 5-monooxygenase1.14.15.10.454
4py6R78Bromodomain protein, putative/0.454
4rbs0RVMetallo-beta-lactamase type 2/0.454
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.454
5iubCLRAdenosine receptor A2a/0.454
1db48INPhospholipase A2, membrane associated/0.453
1ek2CDUBifunctional epoxide hydrolase 2/0.453
1rkhVD2Vitamin D3 receptor/0.453
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.453
1rx8FOLDihydrofolate reductase1.5.1.30.453
1tl1H18Gag-Pol polyprotein2.7.7.490.453
1uy7PU4Heat shock protein HSP 90-alpha/0.453
1xiuREARetinoic acid receptor RXR/0.453
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2jj3JJ3Estrogen receptor beta/0.453
2nr4FMNConserved protein/0.453
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2p7zOHTEstrogen-related receptor gamma/0.453
2vbpVB1Isopenicillin N synthase1.21.3.10.453
3c3eFO12-phospho-L-lactate transferase/0.453
3ds6A17Mitogen-activated protein kinase 14/0.453
3e7iB2Nitric oxide synthase, inducible1.14.13.390.453
3juqAKDPhenazine biosynthesis protein A/B/0.453
3k3kA8SAbscisic acid receptor PYR1/0.453
3lalKRVGag-Pol polyprotein2.7.7.490.453
3qzyFADFAD-linked sulfhydryl oxidase/0.453
3thrC2FGlycine N-methyltransferase2.1.1.200.453
3vufADPGranule-bound starch synthase 1, chloroplastic/amyloplastic2.4.1.2420.453
4c9oCAMCytochrome P450/0.453
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.453
4ec3RENReticuline oxidase1.21.3.30.453
4g1d0VKVitamin D3 receptor A/0.453
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.453
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.453
4jvmXDIEstrogen sulfotransferase2.8.2.40.453
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
4qii2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.453
5cb5APRO-acetyl-ADP-ribose deacetylase/0.453
1drbMTXDihydrofolate reductase1.5.1.30.452
1f20FADNitric oxide synthase, brain1.14.13.390.452
1f5fDHTSex hormone-binding globulin/0.452
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1yhoTRRDihydrofolate reductase1.5.1.30.452
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.452
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2bbqPFGThymidylate synthase/0.452
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2hcdBIVVitamin D3 receptor A/0.452
2hm9TRRDihydrofolate reductase1.5.1.30.452
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2qe4JJ3Estrogen receptor/0.452
2y6fM9FIsopenicillin N synthase1.21.3.10.452
2yac937Serine/threonine-protein kinase PLK12.7.11.210.452
3bqdDAYGlucocorticoid receptor/0.452
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.452
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3gkiCLRNiemann-Pick C1 protein/0.452
3hub469Mitogen-activated protein kinase 14/0.452
3kb0A8SAbscisic acid receptor PYL2/0.452
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
3tm5SFGUncharacterized protein/0.452
3w5rLOAVitamin D3 receptor/0.452
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.452
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.452
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.452
4o701QKBromodomain-containing protein 4/0.452
4pp6STLEstrogen receptor/0.452
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.452
4ubsDIFPentalenic acid synthase1.14.15.110.452
1bq1CB3Thymidylate synthase/0.451
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1gs3EQUSteroid Delta-isomerase5.3.3.10.451
1jutLYDThymidylate synthase/0.451
1nhz486Glucocorticoid receptor/0.451
1s7gNADNAD-dependent protein deacylase 2/0.451
1tlcF89Thymidylate synthase/0.451
1x7b041Estrogen receptor beta/0.451
1xq3R18Androgen receptor/0.451
2cl5BIECatechol O-methyltransferase2.1.1.60.451
2gm12AZKinesin-like protein KIF11/0.451
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.451
2ojj82AMitogen-activated protein kinase 12.7.11.240.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
2xf3J01Uncharacterized protein/0.451
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.451
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3fknFKNMitogen-activated protein kinase 14/0.451
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3lanKBTGag-Pol polyprotein2.7.7.490.451
3nbzGTPGTP-binding nuclear protein Ran/0.451
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
3qlhT27Gag-Pol polyprotein2.7.7.490.451
3rthRTHBeta-secretase 13.4.23.460.451
4gg70J8Hepatocyte growth factor receptor2.7.10.10.451
4ho5DAUGlucose-1-phosphate thymidylyltransferase/0.451
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4o71CPBBromodomain-containing protein 4/0.451
4uqsINENitric oxide synthase oxygenase1.14.13.1650.451
4uymVOR14-alpha sterol demethylase Cyp51B/0.451
4xoiGTPTransforming protein RhoA/0.451
5h8tRTLRetinol-binding protein 1/0.451
1dcyI3NPhospholipase A2, membrane associated/0.450
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.450
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.450
1n5vNOMActVA 6 protein/0.450
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1pq6965Oxysterols receptor LXR-beta/0.450
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.450
1x7jGENEstrogen receptor beta/0.450
1xuzMMNCapsule biosynthesis protein/0.450
2gqrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.450
2io6330Wee1-like protein kinase2.7.10.20.450
2iypNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.450
2qboCAMCamphor 5-monooxygenase1.14.15.10.450
2r6jNDPEugenol synthase 11.1.1.3180.450
2vn1FK5Peptidylprolyl isomerase/0.450
2vrbNAPTriphenylmethane reductase/0.450
2yekEAMBromodomain-containing protein 2/0.450
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.450
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.450
3nhrRZWRibosyldihydronicotinamide dehydrogenase [quinone]/0.450
3nmvPYVAbscisic acid receptor PYL2/0.450
3nn6HNK6-hydroxy-L-nicotine oxidase/0.450
3vtcTK3Vitamin D3 receptor/0.450
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.450
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4dm8REARetinoic acid receptor beta/0.450
4dpy2P0Mevalonate diphosphate decarboxylase/0.450
4g48PZBMycocyclosin synthase1.14.21.90.450
4gevCB3Thymidylate synthase/0.450
4ise1FWGlucokinase2.7.1.20.450
4iyg1HUStrictosidine synthase4.3.3.20.450
4jsfQJ4Nitric oxide synthase, brain1.14.13.390.450
4oeaDHTAndrogen receptor/0.450
4v12POGMaoC like domain protein/0.450
4xwtU5PRibonuclease J/0.450
5dstSAHProtein arginine N-methyltransferase 82.1.10.450
1fd0254Retinoic acid receptor gamma/0.449
1kmvLIIDihydrofolate reductase1.5.1.30.449
1ogxEQUSteroid Delta-isomerase5.3.3.10.449
1tduCB3Thymidylate synthase/0.449
2aclREARetinoic acid receptor RXR-alpha/0.449
2bxoOPBSerum albumin/0.449
2feuCAMCamphor 5-monooxygenase1.14.15.10.449
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.449
2punACPMethylthioribose kinase2.7.1.1000.449
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3h3qH13Collagen type IV alpha-3-binding protein/0.449
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3n65XFJNitric oxide synthase, brain1.14.13.390.449
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.449
3ujlA8SAbscisic acid receptor PYL2/0.449
3v1s0LHStrictosidine synthase4.3.3.20.449
3zrbOR8Progesterone receptor/0.449
3zsh469Mitogen-activated protein kinase 14/0.449
4as94QSATP-dependent molecular chaperone HSP82/0.449
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.449
4gqe6KJNitric oxide synthase, brain1.14.13.390.449
4ifvT27Gag-Pol polyprotein2.7.7.490.449
4jtrIZPAldo-keto reductase family 1 member C2/0.449
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
4pd6URINucleoside permease/0.449
5ej5TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.449
5gcnCOAHAT A1/0.449
1enpNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.448
1iwjCAMCamphor 5-monooxygenase1.14.15.10.448
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.448
1jtqLY3Thymidylate synthase/0.448
1m9m6NINitric oxide synthase, endothelial1.14.13.390.448
1u9e397Estrogen receptor beta/0.448
1wxjIPLTryptophan synthase alpha chain/0.448
1zprCB3Thymidylate synthase/0.448
2f8lSAMLmo1582 protein/0.448
2hk9NAPShikimate dehydrogenase (NADP(+))/0.448
2jn3JN3Fatty acid-binding protein, liver/0.448
2m56CAMCamphor 5-monooxygenase1.14.15.10.448
2pulACPMethylthioribose kinase2.7.1.1000.448
2q9fC3SCholesterol 24-hydroxylase/0.448
2qbmCAMCamphor 5-monooxygenase1.14.15.10.448
2qw8NAPEugenol synthase 11.1.1.3180.448
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.448
3af3GCPPantothenate kinase2.7.1.330.448
3cqeP91Wee1-like protein kinase2.7.10.20.448
3dmjGWEPol protein/0.448
3ewsADPATP-dependent RNA helicase DDX19B3.6.4.130.448
3fr28CAFatty acid-binding protein, adipocyte/0.448
3gieACPSensor histidine kinase DesK2.7.13.30.448
3p99LNPLanosterol 14-alpha-demethylase/0.448
3pqbVGPPutative oxidoreductase/0.448
3s79ASDAromatase1.14.14.140.448
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.448
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.448
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.448
4a2jAS0Progesterone receptor/0.448
4a51DQ8Kinesin-like protein KIF11/0.448
4b4gKKTGlucose-1-phosphate thymidylyltransferase/0.448
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.448
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.448
4nmcFADBifunctional protein PutA/0.448
4ofrDHTAndrogen receptor/0.448
4y7cNAPNADPH--cytochrome P450 reductase/0.448
4yaf2AMNADPH--cytochrome P450 reductase/0.448
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1be4PCGNucleoside diphosphate kinase A 22.7.4.60.447
1db56INPhospholipase A2, membrane associated/0.447
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.447
1osvCHCBile acid receptor/0.447
1phePIYCamphor 5-monooxygenase1.14.15.10.447
1pqc444Oxysterols receptor LXR-beta/0.447
1uhlMEIRetinoic acid receptor RXR-beta/0.447
1x76697Estrogen receptor beta/0.447
2a3iC0RMineralocorticoid receptor/0.447
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2cdaNAPGlucose 1-dehydrogenase/0.447
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
2hamC33Vitamin D3 receptor/0.447
2iyaZIOOleandomycin glycosyltransferase/0.447
2w71L23Biotin carboxylase6.3.4.140.447
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.447
3d75NBBPheromone-binding protein ASP1/0.447
3da24MDCarbonic anhydrase 134.2.1.10.447
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.447
3gkjHC3Niemann-Pick C1 protein/0.447
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.447
4cp4CAMCamphor 5-monooxygenase1.14.15.10.447
4enhFVXCholesterol 24-hydroxylase/0.447
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.447
4iae1DXAlr2278 protein/0.447
4kodADPTransitional endoplasmic reticulum ATPase3.6.4.60.447
4q71FADBifunctional protein PutA/0.447
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.447
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.447
4zgsNADPutative D-lactate dehydrogenase/0.447
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.446
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.446
1tvrTB9Gag-Pol polyprotein2.7.7.490.446
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.446
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.446
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2nnqT4BFatty acid-binding protein, adipocyte/0.446
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.446
2pnuENMAndrogen receptor/0.446
2qimZEAClass 10 plant pathogenesis-related protein/0.446
2zcePYLPyrrolysine--tRNA ligase/0.446
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3ielU5PRibonuclease TTHA02523.10.446
3imxB84Glucokinase2.7.1.20.446
3n60XFNNitric oxide synthase, brain1.14.13.390.446
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3tmz06XCytochrome P450 2B41.14.14.10.446
3v94WYQPhosphodiesterase/0.446
3vgnFNNSteroid Delta-isomerase5.3.3.10.446
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4at0FADPossible succinate dehydrogenase/0.446
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.446
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.446
4hy6FJ1Heat shock protein HSP 90-alpha/0.446
4jvnYUGEstrogen sulfotransferase2.8.2.40.446
4pb25UDNucleoside permease/0.446
4pnmNU1Tankyrase-22.4.2.300.446
4xivACPChemotaxis protein CheA2.7.13.30.446
1tduDURThymidylate synthase/0.445
1txiTX5Vitamin D3 receptor/0.445
1uyuCAMCamphor 5-monooxygenase1.14.15.10.445
1xuoLA1Integrin alpha-L/0.445
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.445
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2j62GSZO-GlcNAcase NagJ/0.445
2od7A1RNAD-dependent protein deacetylase HST23.5.10.445
2rtlIMIStreptavidin/0.445
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
2w9gTOPDihydrofolate reductase1.5.1.30.445
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.445
2ydoADNAdenosine receptor A2a/0.445
2ylqTESAndrogen receptor/0.445
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.445
3fl4FL4Mitogen-activated protein kinase 14/0.445
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.445
3h1vTK1Glucokinase2.7.1.20.445
3h4vDVPPteridine reductase 11.5.1.330.445
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
3ntaFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.445
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
3ua506XCytochrome P450 2B61.14.130.445
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.445
3zc3FADFerredoxin--NADP reductase1.18.1.20.445
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4fhd0TTSpore photoproduct lyase/0.445
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.445
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.445
4jlt8PRCytochrome P450 2B41.14.14.10.445
4l49CAMCamphor 5-monooxygenase1.14.15.10.445
4nc3ERM5-hydroxytryptamine receptor 2B/0.445
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
4pdaCTNNucleoside permease/0.445
4xymCOAAcyl-CoA synthetase (NDP forming)/0.445
4y8vADPAcyl-CoA synthetase (NDP forming)/0.445
4y9uNAPNADPH--cytochrome P450 reductase/0.445
4zp0DXCMultidrug transporter MdfA/0.445
5iqiGNPBifunctional AAC/APH2.3.10.445
1culFOKAdenylate cyclase type 2/0.444
1culFOKAdenylate cyclase type 5/0.444
1dz4CAMCamphor 5-monooxygenase1.14.15.10.444
1dz6CAMCamphor 5-monooxygenase1.14.15.10.444
1e7wMTXPteridine reductase 11.5.1.330.444
1ie9VDXVitamin D3 receptor/0.444
1mrqSTRAldo-keto reductase family 1 member C1/0.444
1rx1NAPDihydrofolate reductase1.5.1.30.444
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1vkgCRIHistone deacetylase 83.5.1.980.444
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.444
1w7h3IPMitogen-activated protein kinase 14/0.444
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.444
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
2fpcSCGStrictosidine synthase4.3.3.20.444
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.444
2olcADPMethylthioribose kinase2.7.1.1000.444
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.444
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.444
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.444
3ebf332Nitric oxide synthase, inducible1.14.13.390.444
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.444
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.444
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3koo24DBifunctional epoxide hydrolase 23.3.2.100.444
3negPYVAbscisic acid receptor PYL1/0.444
3u8hBHPPhospholipase A2, membrane associated/0.444
4c9pCAMCytochrome P450/0.444
4dhyS41Glucokinase2.7.1.20.444
4ejh0QACytochrome P450 2A131.14.14.10.444
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.444
4kfbT27Gag-Pol polyprotein2.7.7.490.444
4l4dCAMCamphor 5-monooxygenase1.14.15.10.444
4lt63ATPoly(A) polymerase gamma2.7.7.190.444
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.444
4o761M3Bromodomain-containing protein 4/0.444
4othDRNSerine/threonine-protein kinase N1/0.444
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
5ab7MLCNonspecific lipid-transfer protein, putative/0.444
1a8t061Metallo-beta-lactamase type 2/0.443
1aiqCB3Thymidylate synthase/0.443
1crbRTLRetinol-binding protein 1/0.443
1db1VDXVitamin D3 receptor/0.443
1dnaCB3Thymidylate synthase/0.443
1e3vDXCSteroid Delta-isomerase5.3.3.10.443
1fbyREARetinoic acid receptor RXR-alpha/0.443
1galFADGlucose oxidase1.1.3.40.443
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1kruIPTGalactoside O-acetyltransferase2.3.1.180.443
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1sqbAZOCytochrome b/0.443
1wxyFRKAdenosine deaminase3.5.4.40.443
2puiADPMethylthioribose kinase2.7.1.1000.443
2qk8MTXDihydrofolate reductase/0.443
2wkmPFYHepatocyte growth factor receptor2.7.10.10.443
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.443
2z7gEH9Adenosine deaminase3.5.4.40.443
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.443
3cth319Hepatocyte growth factor receptor2.7.10.10.443
3dolGWIPol protein/0.443
3e7tB14Nitric oxide synthase, inducible1.14.13.390.443
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3fl9TOPDihydrofolate reductase/0.443
3ixp834Ecdysone receptor/0.443
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.443
3wv9FEGHmd co-occurring protein HcgE/0.443
4bquCLRJapanin/0.443
4dm6TTBRetinoic acid receptor beta/0.443
4ds8A8SAbscisic acid receptor PYL3/0.443
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.443
4iarERM5-hydroxytryptamine receptor 1B/0.443
4mv3ACPBiotin carboxylase6.3.4.140.443
4rh10TTSpore photoproduct lyase/0.443
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.443
4yaw2AMNADPH--cytochrome P450 reductase/0.443
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.442
1e92HBIPteridine reductase 11.5.1.330.442
1ihiIU5Aldo-keto reductase family 1 member C2/0.442
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1ju6LYAThymidylate synthase2.1.1.450.442
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.442
1n71COAAac(6')-Ii protein/0.442
1oh0EQUSteroid Delta-isomerase5.3.3.10.442
1rszDIHPurine nucleoside phosphorylase2.4.2.10.442
1s19MC9Vitamin D3 receptor/0.442
1s9qOHTEstrogen-related receptor gamma/0.442
1t85CAMCamphor 5-monooxygenase1.14.15.10.442
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.442
1uyePU9Heat shock protein HSP 90-alpha/0.442
1xe65FPPlasmepsin-23.4.23.390.442
1xp1AIHEstrogen receptor/0.442
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2ab8MTPAdenosine kinase2.7.1.200.442
2cd8PXICytochrome P450 monooxygenase PikC/0.442
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2jfz003Glutamate racemase/0.442
2on6IMHPurine nucleoside phosphorylase2.4.2.10.442
2qblCAMCamphor 5-monooxygenase1.14.15.10.442
2qxxTTPdCTP deaminase3.5.4.130.442
2vz0D64Pteridine reductase/0.442
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.442
2yhdTESAndrogen receptor/0.442
2zsdCOAPantothenate kinase2.7.1.330.442
3acy702Dehydrosqualene synthase/0.442
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3e6t1A2Nitric oxide synthase, inducible1.14.13.390.442
3mjrAC2Deoxycytidine kinase2.7.1.740.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
3q2mCKISpectinomycin phosphotransferase/0.442
3tguWF3Cytochrome b/0.442
3vrvYSDVitamin D3 receptor/0.442
3vwsVWSGenome polyprotein/0.442
4a99MIYTetX family tetracycline inactivation enzyme/0.442
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.442
4b8zGDPGDP-L-fucose synthase1.1.1.2710.442
4efuEFUHeat shock protein HSP 90-alpha/0.442
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.442
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.442
4ig3T27Gag-Pol polyprotein2.7.7.490.442
4j7uYTZSepiapterin reductase1.1.1.1530.442
4jq4IMNAldo-keto reductase family 1 member C2/0.442
4udcDEXGlucocorticoid receptor/0.442
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.442
4xo7ASDAldo-keto reductase family 1 member C2/0.442
5dc5B3NHistone deacetylase 83.5.1.980.442
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.442
1bmfADPATP synthase subunit alpha, mitochondrial/0.441
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.441
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.441
1fcy564Retinoic acid receptor gamma/0.441
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1jlcFTCGag-Pol polyprotein2.7.7.490.441
1khrVIRStreptogramin A acetyltransferase2.3.10.441
1kt5RTLRetinol-binding protein 4/0.441
1kt6RTLRetinol-binding protein 4/0.441
1o76CAMCamphor 5-monooxygenase1.14.15.10.441
1q66KMBQueuine tRNA-ribosyltransferase2.4.2.290.441
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.441
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2bj4OHTEstrogen receptor/0.441
2cy0NAPShikimate dehydrogenase (NADP(+))/0.441
2fznFADBifunctional protein PutA1.5.5.20.441
2hasC3OVitamin D3 receptor/0.441
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.441
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
2pitDHTAndrogen receptor/0.441
2vqoTFGHistone deacetylase 43.5.1.980.441
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.441
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.441
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
3br3ETHTH-type transcriptional regulator QacR/0.441
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.441
3cz09ODPheromone-binding protein ASP1/0.441
3drrR8EGag-Pol polyprotein2.7.7.490.441
3fu83DMLaccase-11.10.3.20.441
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.441
3h1jSMACytochrome b/0.441
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.441
3kb3A8SAbscisic acid receptor PYL2/0.441
3o0iP54Heat shock protein HSP 90-alpha/0.441
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3vt3VDXVitamin D3 receptor/0.441
3vt8YI3Vitamin D3 receptor/0.441
3zqtTESAndrogen receptor/0.441
4a83DXCMajor pollen allergen Bet v 1-A/0.441
4au7SAHHistone-lysine N-methyltransferase KMT5C2.1.1.430.441
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.441
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.441
4g1nNZTPyruvate kinase PKM2.7.1.400.441
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.441
4k4eK4ETankyrase-12.4.2.300.441
4mv8ACPBiotin carboxylase6.3.4.140.441
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.441
4wa9AXITyrosine-protein kinase ABL12.7.10.20.441
4zowCLMMultidrug transporter MdfA/0.441
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.441
5eccNAPDehydrofolate reductase type I/0.441
8catNDPCatalase1.11.1.60.441
1gs4ZK5Androgen receptor/0.440
1k749CRRetinoic acid receptor RXR-alpha/0.440
1lb9DNQGlutamate receptor 2/0.440
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.440
1trgCB3Thymidylate synthase/0.440
1tsdF89Thymidylate synthase/0.440
1uy8PU5Heat shock protein HSP 90-alpha/0.440
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
2cppCAMCamphor 5-monooxygenase1.14.15.10.440
2j7xESTEstrogen receptor beta/0.440
2lbdREARetinoic acid receptor gamma/0.440
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2piwDHTAndrogen receptor/0.440
2vzmNRBCytochrome P450 monooxygenase PikC/0.440
2wd8VGFPteridine reductase/0.440
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.440
2ykcYKCHeat shock protein HSP 90-alpha/0.440
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3bfa9ODOdorant binding protein ASP1/0.440
3bgxMEFThymidylate synthase/0.440
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.440
3eah327Nitric oxide synthase, endothelial1.14.13.390.440
3k1wBFXRenin3.4.23.150.440
3lfeZ84Mitogen-activated protein kinase 14/0.440
3lkhLT6Genome polyprotein2.7.7.480.440
3mdvCL6Cholesterol 24-hydroxylase/0.440
3nlw3XFNitric oxide synthase, brain1.14.13.390.440
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3owuEQUSteroid Delta-isomerase5.3.3.10.440
3pl8FADPyranose 2-oxidase/0.440
3s1sSAHRestriction endonuclease BpuSI/0.440
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.440
3uftHW7Nitric oxide synthase, brain1.14.13.390.440
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4apuOR8Progesterone receptor/0.440
4b6uM7GEukaryotic translation initiation factor 4E type 3/0.440
4bfzZVZPantothenate kinase2.7.1.330.440
4ejgNCTCytochrome P450 2A131.14.14.10.440
4fhf0TTSpore photoproduct lyase/0.440
4ib4ERM5-hydroxytryptamine receptor 2B/0.440
4iq71G9Mycocyclosin synthase1.14.21.90.440
4k6i9RARetinoic acid receptor RXR-alpha/0.440
4l17DNQGlutamate receptor 2/0.440
4li61XOTankyrase-12.4.2.300.440
4mfb29TGag-Pol polyprotein2.7.7.490.440
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440
5g53NECAdenosine receptor A2a/0.440