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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2b56UTPRNA editing complex protein MP57

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2b56UTPRNA editing complex protein MP57/1.000
2b51UTPRNA editing complex protein MP57/0.527
2q0cCTPPoly(A) polymerase, putative/0.467
2q0dATPPoly(A) polymerase, putative/0.463
2q0gUPUPoly(A) polymerase, putative/0.459
2ikfUTPPoly(A) polymerase, putative/0.453
2nomDUTPoly(A) polymerase, putative/0.441