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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.91.000
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.554
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.521
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.516
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.494
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.488
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
3fnfJPMEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.443
1diuBDMDihydrofolate reductase1.5.1.30.441