sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 1.000 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.654 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.642 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.602 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.582 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.501 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.490 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.489 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.488 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.487 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.485 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.484 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.483 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.483 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.482 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.480 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.479 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.478 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.476 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.475 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.474 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.473 | |
| 1osv | CHC | Bile acid receptor | / | 0.473 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.473 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.472 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.471 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.471 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.471 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.470 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.470 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.470 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.469 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.469 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.469 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.467 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.467 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.466 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.466 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.465 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.465 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.463 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.463 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.463 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.462 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.462 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.461 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.461 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.461 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.461 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.461 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.460 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.460 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.460 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.460 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.459 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.459 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.459 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.459 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.458 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.458 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.458 | |
| 4uux | APR | CinA-like protein | / | 0.458 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.457 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.457 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.457 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.457 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.456 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.456 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.455 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.455 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.454 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.454 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.453 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.453 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.453 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.452 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.452 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.452 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.451 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.451 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.451 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.450 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.450 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.450 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.450 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.450 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.449 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.449 | |
| 2xcl | ANP | Phosphoribosylamine--glycine ligase | / | 0.449 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.449 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.449 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.449 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.449 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 1yin | CM3 | Estrogen receptor | / | 0.448 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.448 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.448 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.448 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.448 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.448 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.448 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.448 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.447 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.447 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.447 | |
| 3h1j | SMA | Cytochrome b | / | 0.447 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.447 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.447 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1sn5 | T3 | Transthyretin | / | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.446 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3aba | FLI | Cytochrome P450 | / | 0.446 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.446 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.446 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.446 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.446 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.444 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.444 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.444 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.444 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 3zux | TCH | Transporter | / | 0.444 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.444 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.443 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2jd0 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.443 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.443 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.443 | |
| 5j4e | FMN | Sensory box protein | / | 0.443 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.442 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 2bx8 | AZQ | Serum albumin | / | 0.442 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.442 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.442 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.442 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.442 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.442 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.442 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.442 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.442 | |
| 5doz | NDP | JamJ | / | 0.442 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.442 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.441 | |
| 3ruv | ANP | Chaperonin | / | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3up3 | XCA | aceDAF-12 | / | 0.441 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.441 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.441 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.441 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.441 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1ppj | ANY | Cytochrome b | / | 0.440 | |
| 1qvn | FRI | Interleukin-2 | / | 0.440 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.440 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.440 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.440 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3liv | E16 | Protease | / | 0.440 | |
| 3lu8 | IQX | Serum albumin | / | 0.440 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.440 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.440 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.440 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.440 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.440 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.440 |