sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2avi | BTN | Avidin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2avi | BTN | Avidin | / | 1.000 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.614 | |
| 1avd | BTN | Avidin | / | 0.608 | |
| 2uyw | BTN | Avd protein | / | 0.599 | |
| 2c4i | BTN | Avidin | / | 0.580 | |
| 1mk5 | BTN | Streptavidin | / | 0.540 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.539 | |
| 1stp | BTN | Streptavidin | / | 0.537 | |
| 2izh | BTN | Streptavidin | / | 0.535 | |
| 2rtf | BTN | Streptavidin | / | 0.532 | |
| 2y3f | BTN | Streptavidin | / | 0.529 | |
| 2uz2 | BTN | Avd protein | / | 0.528 | |
| 3vgw | NVZ | Avidin | / | 0.527 | |
| 4bx7 | B4F | Streptavidin | / | 0.527 | |
| 2rtn | IMI | Streptavidin | / | 0.524 | |
| 3ry2 | BTN | Streptavidin | / | 0.523 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.521 | |
| 2izl | IMI | Streptavidin | / | 0.521 | |
| 4dne | DTB | Streptavidin | / | 0.521 | |
| 2rto | IMI | Streptavidin | / | 0.519 | |
| 4bj8 | BTN | Avidin | / | 0.519 | |
| 4gda | BTN | Streptavidin | / | 0.518 | |
| 3wyq | BTN | Streptavidin | / | 0.516 | |
| 2izf | BTN | Streptavidin | / | 0.513 | |
| 4z28 | BTN | Hoefavidin | / | 0.512 | |
| 1lcw | SHM | Streptavidin | / | 0.510 | |
| 1swp | BTQ | Streptavidin | / | 0.510 | |
| 1swt | BTN | Streptavidin | / | 0.509 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.509 | |
| 2rtg | BTN | Streptavidin | / | 0.509 | |
| 2rtd | BTN | Streptavidin | / | 0.508 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 2rte | BTN | Streptavidin | / | 0.505 | |
| 1nqm | BTN | Streptavidin | / | 0.503 | |
| 3vhh | VHH | Avidin | / | 0.503 | |
| 1srg | MHB | Streptavidin | / | 0.502 | |
| 2izg | BTN | Streptavidin | / | 0.502 | |
| 1rxh | BNI | Streptavidin | / | 0.500 | |
| 3wzn | BTN | Streptavidin | / | 0.500 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.498 | |
| 1swr | BTN | Streptavidin | / | 0.495 | |
| 2rtr | IMI | Streptavidin | / | 0.495 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.493 | |
| 1i9h | BNI | Streptavidin | / | 0.492 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.490 | |
| 3arv | SAU | Chitinase A | / | 0.489 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.487 | |
| 1sre | HAB | Streptavidin | / | 0.486 | |
| 1sri | DMB | Streptavidin | / | 0.486 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.486 | |
| 1swn | BTN | Streptavidin | / | 0.485 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.484 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.482 | |
| 1zdw | FLV | Prenyltransferase | / | 0.481 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.481 | |
| 1luq | BTN | Streptavidin | / | 0.480 | |
| 2rtq | IMI | Streptavidin | / | 0.480 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.480 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.480 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.479 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.478 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.478 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.476 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.474 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.474 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.474 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.473 | |
| 1lcz | BH7 | Streptavidin | / | 0.472 | |
| 1mep | BTN | Streptavidin | / | 0.472 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.472 | |
| 1df8 | BTN | Streptavidin | / | 0.471 | |
| 2rtp | IMI | Streptavidin | / | 0.471 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.471 | |
| 3wyp | BSO | Streptavidin | / | 0.470 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.469 | |
| 1nc9 | IMI | Streptavidin | / | 0.469 | |
| 1swe | BTN | Streptavidin | / | 0.469 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.468 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.468 | |
| 1srf | MTB | Streptavidin | / | 0.467 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2izj | BTN | Streptavidin | / | 0.467 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.466 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.466 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.466 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.466 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.466 | |
| 1srh | MOB | Streptavidin | / | 0.465 | |
| 1swd | BTN | Streptavidin | / | 0.465 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.465 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.465 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.464 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.464 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.463 | |
| 1tys | DHF | Thymidylate synthase | / | 0.463 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 3up3 | XCA | aceDAF-12 | / | 0.463 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.463 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.462 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2rtm | IMI | Streptavidin | / | 0.461 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.461 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.461 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.461 | |
| 5cfn | 2BA | Stimulator of interferon genes protein | / | 0.461 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.460 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.460 | |
| 5a3b | APR | SIR2 family protein | / | 0.460 | |
| 5dp2 | NAP | CurF | / | 0.460 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.459 | |
| 2zsc | BTN | Tamavidin2 | / | 0.459 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.459 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.459 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.459 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.459 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.459 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.459 | |
| 1swp | BTN | Streptavidin | / | 0.458 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.458 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.458 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2izi | BTN | Streptavidin | / | 0.457 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.457 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.457 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.457 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.457 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.457 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.457 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.455 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.455 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.455 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.455 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.455 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.454 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.454 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.454 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.453 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.453 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.453 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.453 | |
| 3rdq | DTB | Streptavidin | / | 0.453 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.453 | |
| 4yvb | BTN | Streptavidin | / | 0.453 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.452 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.452 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.452 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.452 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.452 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.451 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.451 | |
| 2izk | GLL | Streptavidin | / | 0.451 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.451 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.451 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.451 | |
| 4j7g | TRH | PCZA361.3 | / | 0.451 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.451 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.450 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.450 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 4xd1 | T3Q | Qdtf | / | 0.450 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.449 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.449 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.449 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.449 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.449 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.449 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.448 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.448 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.448 | |
| 2rti | GLL | Streptavidin | / | 0.448 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.448 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.448 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.448 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.448 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.448 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.448 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.447 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.447 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.447 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.447 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.447 | |
| 4die | C5P | Cytidylate kinase | / | 0.447 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.447 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.446 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.446 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.446 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.446 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.446 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.446 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.445 | |
| 2oa7 | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.445 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.445 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.445 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.445 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.444 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.444 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.444 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.444 | |
| 4pd6 | URI | Nucleoside permease | / | 0.444 | |
| 4yp5 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.443 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.443 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.443 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.443 | |
| 1srj | NAB | Streptavidin | / | 0.443 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.443 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.443 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.443 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.443 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.443 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.443 | |
| 4bqu | CLR | Japanin | / | 0.443 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.442 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.442 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.442 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4l4x | NDP | AmphI | / | 0.442 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.441 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.441 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 1ndj | BTN | Streptavidin | / | 0.441 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.441 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.441 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.441 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.441 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.441 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.441 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.441 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.441 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.441 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1ofg | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.440 | |
| 1osv | CHC | Bile acid receptor | / | 0.440 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3ec7 | NAD | Inositol 2-dehydrogenase | / | 0.440 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.440 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.440 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4m52 | M52 | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 |