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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2agtFIDAldose reductase1.1.1.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2agtFIDAldose reductase1.1.1.211.000
2pd9FIDAldose reductase1.1.1.210.771
2pdmZSTAldose reductase1.1.1.210.742
2pdwFIDAldose reductase1.1.1.210.722
1z8962PAldose reductase1.1.1.210.694
1t40ID5Aldose reductase1.1.1.210.688
2iki388Aldose reductase1.1.1.210.663
2pdkSBIAldose reductase1.1.1.210.663
2pdfZSTAldose reductase1.1.1.210.642
2f2kTGGAldose reductase1.1.1.210.640
2pdu393Aldose reductase1.1.1.210.635
4gca2X9Aldose reductase1.1.1.210.633
3p2vDOYAldose reductase1.1.1.210.632
4gabFIDAldo-keto reductase family 1 member B101.1.10.631
1ekoI84Aldose reductase1.1.1.210.625
3m4h388Aldose reductase1.1.1.210.625
2pdyFIDAldose reductase1.1.1.210.624
5liu388Aldo-keto reductase family 1 member B101.1.10.623
2is72CLAldose reductase1.1.1.210.621
3lz5LDTAldose reductase1.1.1.210.619
2ikj393Aldose reductase1.1.1.210.614
2inzOHPAldose reductase1.1.1.210.613
2pdj393Aldose reductase1.1.1.210.611
3u2cSUZAldose reductase1.1.1.210.610
2nvcITAAldose reductase1.1.1.210.609
3lboLDTAldose reductase1.1.1.210.607
2iqdLPAAldose reductase1.1.1.210.602
3s3gTLTAldose reductase1.1.1.210.602
1ef3FIDAldose reductase1.1.1.210.600
2fz8ZSTAldose reductase1.1.1.210.600
3v35NTIAldose reductase1.1.1.210.600
3lqlLDTAldose reductase1.1.1.210.599
2pdxZSTAldose reductase1.1.1.210.598
1pwmFIDAldose reductase1.1.1.210.596
3mb9ZSTAldose reductase1.1.1.210.595
1ieiZESAldose reductase1.1.1.210.593
2hv5ZSTAldose reductase1.1.1.210.593
4yu153NAldose reductase1.1.1.210.592
1zuaTOLAldo-keto reductase family 1 member B101.1.10.589
2i17LDTAldose reductase1.1.1.210.587
2pzn393Aldose reductase1.1.1.210.586
3ghtLDTAldose reductase1.1.1.210.580
4wevSUZAldo-keto reductase family 1 member B101.1.10.579
2duxZSTAldose reductase1.1.1.210.578
1ah0SBIAldose reductase1.1.1.210.577
3ghuLDTAldose reductase1.1.1.210.577
2dv0ZSTAldose reductase1.1.1.210.576
1t41ID5Aldose reductase1.1.1.210.572
2fz9ZSTAldose reductase1.1.1.210.571
3m64393Aldose reductase1.1.1.210.570
2fzdTOLAldose reductase1.1.1.210.563
2pdq47DAldose reductase1.1.1.210.563
1el3I84Aldose reductase1.1.1.210.559
2i16LDTAldose reductase1.1.1.210.556
3mc5393Aldose reductase1.1.1.210.555
2qxwLDTAldose reductase1.1.1.210.554
3lenZSTAldose reductase1.1.1.210.553
2hvnZSTAldose reductase1.1.1.210.552
3ld5LDTAldose reductase1.1.1.210.545
2pdn47DAldose reductase1.1.1.210.543
2pdp393Aldose reductase1.1.1.210.543
1us0LDTAldose reductase1.1.1.210.541
3ghsLDTAldose reductase1.1.1.210.541
2pdc393Aldose reductase1.1.1.210.538
3ghrLDTAldose reductase1.1.1.210.535
2ikhLITAldose reductase1.1.1.210.533
1z3n3NAAldose reductase1.1.1.210.532
1p0pBCHCholinesterase3.1.1.80.530
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.530
2pdlTOLAldose reductase1.1.1.210.527
1kmsLIHDihydrofolate reductase1.5.1.30.525
2d06ESTSulfotransferase 1A12.8.2.10.525
3g5eQ74Aldose reductase1.1.1.210.525
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.525
3ug8IMNAldo-keto reductase family 1 member C3/0.524
2pb1NFGGlucan 1,3-beta-glucosidase/0.522
2hvoZSTAldose reductase1.1.1.210.521
3qeoLLTDeoxycytidine kinase2.7.1.740.521
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.520
4paaTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.520
2f3815MAldo-keto reductase family 1 member C3/0.519
2bjsACVIsopenicillin N synthase1.21.3.10.518
2pd5ZSTAldose reductase1.1.1.210.517
3t423T4Aldose reductase1.1.1.210.516
4dbw511Aldo-keto reductase family 1 member C3/0.516
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.515
1rxjBNIStreptavidin/0.514
2ipw2CLAldose reductase1.1.1.210.514
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.513
1pwlBFIAldose reductase1.1.1.210.511
1s36CEIObelin/0.511
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.511
5d6lCAUBeta-2 adrenergic receptor/0.511
2fzbTOLAldose reductase1.1.1.210.508
3n0hTOPDihydrofolate reductase1.5.1.30.507
4ga8SBIAldo-keto reductase family 1 member B101.1.10.507
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.506
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.506
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.505
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.503
2pucGUNHTH-type transcriptional repressor PurR/0.503
3f3y4OABile salt sulfotransferase2.8.2.140.503
3v94WYQPhosphodiesterase/0.503
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.503
4fam0SZAldo-keto reductase family 1 member C3/0.501
5dsg0HKMuscarinic acetylcholine receptor M4/0.501
2duzZSTAldose reductase1.1.1.210.500
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.500
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.500
2pdbZSTAldose reductase1.1.1.210.498
2w3mFOLDihydrofolate reductase1.5.1.30.498
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.498
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.498
1w35FADFerredoxin--NADP reductase1.18.1.20.497
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.497
2cekN8TAcetylcholinesterase3.1.1.70.496
2ipjFFAAldo-keto reductase family 1 member C2/0.496
2xujTZ5Acetylcholinesterase3.1.1.70.496
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.496
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.496
4h7c10HAldo-keto reductase family 1 member C3/0.496
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.496
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.496
2yczI32Beta-1 adrenergic receptor/0.496
2a2xNA9Prothrombin3.4.21.50.495
2pdh47DAldose reductase1.1.1.210.495
3r8hZOMAldo-keto reductase family 1 member C3/0.495
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.495
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.495
4n9qFMNFMN-dependent NADH-azoreductase 1/0.495
1ry0PG2Aldo-keto reductase family 1 member C3/0.494
2xuhTZ4Acetylcholinesterase3.1.1.70.494
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.20.494
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.494
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.494
4jtrIZPAldo-keto reductase family 1 member C2/0.494
2rh1CAUBeta-2 adrenergic receptor/0.494
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.493
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.493
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.492
2vbpVB1Isopenicillin N synthase1.21.3.10.492
1ah3TOLAldose reductase1.1.1.210.491
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.491
3gyf51PDihydrofolate reductase1.5.1.30.491
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.490
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.490
3l3rOAGDihydrofolate reductase1.5.1.30.490
4jhiEMUNodulin-13/0.490
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.489
1lkeDOGBilin-binding protein/0.488
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.488
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.488
4qtnNNRNicotinamide riboside transporter PnuC/0.488
1w6jR71Lanosterol synthase5.4.99.70.487
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.487
2qimZEAClass 10 plant pathogenesis-related protein/0.487
4kn104JFolate receptor beta/0.487
1zgbA1EAcetylcholinesterase3.1.1.70.486
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.486
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.486
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.486
4xo7ASDAldo-keto reductase family 1 member C2/0.486
1jf0CZHObelin/0.485
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.485
3d4sTIMBeta-2 adrenergic receptor/0.485
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.484
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.484
2dhfDZFDihydrofolate reductase1.5.1.30.483
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3mjrAC2Deoxycytidine kinase2.7.1.740.483
3n3bFMNProtein NrdI/0.483
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.483
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.483
3uweVJJAldo-keto reductase family 1 member C3/0.483
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.483
4kn2LYAFolate receptor beta/0.483
1frbZSTAldose reductase-related protein 2/0.482
1hb3SCVIsopenicillin N synthase1.21.3.10.482
1ihiIU5Aldo-keto reductase family 1 member C2/0.482
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
4jtqFLPAldo-keto reductase family 1 member C2/0.482
2ycxP32Beta-1 adrenergic receptor/0.482
1c4yIH3Prothrombin3.4.21.50.481
1ry8RUTAldo-keto reductase family 1 member C3/0.481
1s9dAFBCytohesin-2/0.481
1s9dAFBADP-ribosylation factor 1/0.481
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.481
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.481
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.480
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
3c1oNAPEugenol synthase/0.480
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.480
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.480
4jpg1OXPyruvate kinase PKM2.7.1.400.480
3ocw3AMLipoprotein E/0.479
3stdMQ0Scytalone dehydratase4.2.1.940.479
3uyk0CXProbable NDP-rhamnosyltransferase/0.479
4d6qPD2Lysine-specific demethylase 4D1.14.110.479
5stdUNNScytalone dehydratase4.2.1.940.479
2y0468HBeta-1 adrenergic receptor/0.479
5d5aCAUBeta-2 adrenergic receptor/0.479
1el4CTZObelin/0.478
1zq5E04Aldo-keto reductase family 1 member C3/0.478
2vcmM11Isopenicillin N synthase1.21.3.10.478
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.478
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.478
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.478
3n39FMNProtein NrdI/0.478
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.478
4blcNDPCatalase1.11.1.60.478
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.478
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.478
4jq2SUZAldo-keto reductase family 1 member C2/0.478
8catNDPCatalase1.11.1.60.478
1votHUPAcetylcholinesterase3.1.1.70.477
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
3bi6396Wee1-like protein kinase2.7.10.20.477
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.477
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.477
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.477
4kebFOLDihydrofolate reductase1.5.1.30.477
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.476
2aclL05Oxysterols receptor LXR-alpha/0.476
2cbqTH2Neocarzinostatin/0.476
2w6cBM4Acetylcholinesterase3.1.1.70.476
3s3vTOPDihydrofolate reductase1.5.1.30.476
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.476
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.476
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.476
5a4wQCTGlutathione S-transferase F22.5.1.180.476
1d3dBZTProthrombin3.4.21.50.475
1gt5BZQOdorant-binding protein/0.475
1pkfEPDEpothilone C/D epoxidase1.140.475
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.475
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.475
3jq7DX2Pteridine reductase, putative/0.475
3o76GTBGlutathione S-transferase P 12.5.1.180.475
4bfuZVUPantothenate kinase2.7.1.330.475
7catNDPCatalase1.11.1.60.475
1obnASVIsopenicillin N synthase1.21.3.10.474
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
2rqfJH3Hemolymph juvenile hormone binding protein/0.474
3c3dFO12-phospho-L-lactate transferase/0.474
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
1dpmEBPParathion hydrolase3.1.8.10.473
1xf0ASDAldo-keto reductase family 1 member C3/0.473
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.473
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.473
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.473
3a1l2CCCytochrome P450/0.473
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.473
3nxtD2EDihydrofolate reductase1.5.1.30.473
3ocx2AMLipoprotein E/0.473
3r6iJMSAldo-keto reductase family 1 member C3/0.473
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.473
4e7r0NWProthrombin3.4.21.50.473
4m6l21VDihydrofolate reductase1.5.1.30.473
5cxv0HKMuscarinic acetylcholine receptor M1/0.473
1pqc444Oxysterols receptor LXR-beta/0.472
1qtiGNTAcetylcholinesterase3.1.1.70.472
1sjwNGVNogalonic acid methyl ester cyclase/0.472
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.472
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.472
3gi2GHWDihydrofolate reductase1.5.1.30.472
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.472
4li61XOTankyrase-12.4.2.300.472
4u163C0Muscarinic acetylcholine receptor M3/0.472
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.471
1s2cFLFAldo-keto reductase family 1 member C3/0.471
2oadGTBGlutathione S-transferase P 12.5.1.180.471
3d2dRENReticuline oxidase1.21.3.30.471
3mytEQUSteroid Delta-isomerase5.3.3.10.471
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3up3XCAaceDAF-12/0.471
3zoiM2WIsopenicillin N synthase1.21.3.10.471
4dyn0MRNucleoprotein/0.471
4lrrCF9Thymidylate synthase/0.471
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.471
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.471
5epvACPBlue-light-activated histidine kinase2.7.13.30.471
1s3uTQDDihydrofolate reductase1.5.1.30.470
2nnqT4BFatty acid-binding protein, adipocyte/0.470
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.470
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.470
5fljQUEQuercetinase QueD/0.470
1dlrMXADihydrofolate reductase1.5.1.30.469
1odnAPVIsopenicillin N synthase1.21.3.10.469
1pq6965Oxysterols receptor LXR-beta/0.469
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.469
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.469
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.469
2iuzD1HEndochitinase B13.2.1.140.469
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
2xupTZ5Acetylcholinesterase3.1.1.70.469
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.469
4b7zQ4QAcetylcholinesterase3.1.1.70.469
4bjbP34Tankyrase-22.4.2.300.469
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.469
1h35R01Squalene--hopene cyclase4.2.1.1290.468
1vkgCRIHistone deacetylase 83.5.1.980.468
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.468
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3r7mSUZAldo-keto reductase family 1 member C3/0.468
4dyp0MSNucleoprotein/0.468
4i5xFLFAldo-keto reductase family 1 member B101.1.10.468
1blzACVIsopenicillin N synthase1.21.3.10.467
1fmjRTLRetinol dehydratase/0.467
1jdzFMBPurine nucleoside phosphorylase/0.467
1pj6FOLDimethylglycine oxidase1.5.3.100.467
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
2vt4P32Beta-1 adrenergic receptor/0.467
2xi4AFTAcetylcholinesterase3.1.1.70.467
2xnvVU3Soluble acetylcholine receptor/0.467
3ugrIMNAldo-keto reductase family 1 member C3/0.467
3zkyWT4Isopenicillin N synthase1.21.3.10.467
4hmn16JAldo-keto reductase family 1 member C3/0.467
4xoqF42Coenzyme F420:L-glutamate ligase/0.467
4daj0HKMuscarinic acetylcholine receptor M3/0.467
4u140HKMuscarinic acetylcholine receptor M3/0.467
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.466
1hfrMOTDihydrofolate reductase1.5.1.30.466
1m9m6NINitric oxide synthase, endothelial1.14.13.390.466
2tplHPPTyrosine phenol-lyase4.1.99.20.466
2xltNA0Putative flavin-containing monooxygenase/0.466
2xtbKRMAdenosine kinase, putative/0.466
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.466
3gwnFADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.466
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.466
4l0oPLPCystathionine gamma-synthase2.5.1.480.466
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.466
4gbrCAUBeta-2 adrenergic receptor/0.466
1dgfNDPCatalase1.11.1.60.465
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.465
1zgcA2EAcetylcholinesterase3.1.1.70.465
2bd0BIOSepiapterin reductase/0.465
2gpvOHTEstrogen-related receptor gamma/0.465
2vqqTFGHistone deacetylase 43.5.1.980.465
3bm4ADVADP-sugar pyrophosphatase3.6.1.130.465
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
1dhfFOLDihydrofolate reductase1.5.1.30.464
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.464
1lnmDTXBilin-binding protein/0.464
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.464
1w7gMIUProthrombin3.4.21.50.464
2zi63D1Deoxycytidine kinase2.7.1.740.464
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.464
3zkuHCVIsopenicillin N synthase1.21.3.10.464
4dbs0HVAldo-keto reductase family 1 member C3/0.464
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.464
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.464
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.464
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
1dduCB3Thymidylate synthase/0.463
1g3mPCQEstrogen sulfotransferase2.8.2.40.463
1ypjUIBProthrombin3.4.21.50.463
2cjeDUNDUTPase/0.463
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3fvuIACKynurenine--oxoglutarate transaminase 12.6.1.70.463
3ghwGHWDihydrofolate reductase1.5.1.30.463
3m0iZSTAldose reductase1.1.1.210.463
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3v0n4GWHisto-blood group ABO system transferase/0.463
4dk70KSOxysterols receptor LXR-beta/0.463
4jq4IMNAldo-keto reductase family 1 member C2/0.463
4jvmXDIEstrogen sulfotransferase2.8.2.40.463
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
5agkH4BNitric oxide synthase, brain1.14.13.390.463
1acjTHAAcetylcholinesterase3.1.1.70.462
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.462
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.462
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.462
1ut6A8NAcetylcholinesterase3.1.1.70.462
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.462
2cf9348Prothrombin3.4.21.50.462
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.462
2xuqTZ4Acetylcholinesterase3.1.1.70.462
3aezGDPPantothenate kinase2.7.1.330.462
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.462
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3k47D09Dihydrofolate reductase1.5.1.30.462
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.462
3w0tHPULactoylglutathione lyase4.4.1.50.462
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.462
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.462
1bk0ACVIsopenicillin N synthase1.21.3.10.461
1esmCOAPantothenate kinase2.7.1.330.461
1gpnHUBAcetylcholinesterase3.1.1.70.461
1jf2CZHObelin/0.461
1qv0CZHObelin/0.461
1yw8A75Methionine aminopeptidase 2/0.461
2tohHBITyrosine 3-monooxygenase1.14.16.20.461
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.461
2zsdCOAPantothenate kinase2.7.1.330.461
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.461
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.461
3zc3FADFerredoxin--NADP reductase1.18.1.20.461
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.461
4c9wVGH7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.461
4ey6GNTAcetylcholinesterase3.1.1.70.461
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.461
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1q5dEPBEpothilone C/D epoxidase1.140.460
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
2a3bCFFEndochitinase B13.2.1.140.460
2b82ADNClass B acid phosphatase3.1.3.20.460
2gyuHI6Acetylcholinesterase3.1.1.70.460
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.460
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.460
3g72A6TRenin3.4.23.150.460
3i9kNADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.460
3irhDTPHD domain protein/0.460
3ptqNFGBeta-glucosidase 12/0.460
3vo2FADFerredoxin--NADP reductase/0.460
4dkbDUNDeoxyuridine triphosphatase, putative/0.460
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.460
7stdCRPScytalone dehydratase4.2.1.940.460
1az1ALRAldose reductase1.1.1.210.459
1ohkCOPDihydrofolate reductase1.5.1.30.459
1qjgEQUSteroid Delta-isomerase5.3.3.10.459
1rkwPNTHTH-type transcriptional regulator QacR/0.459
1rszDIHPurine nucleoside phosphorylase2.4.2.10.459
1w06W05Isopenicillin N synthase1.21.3.10.459
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1ypgUIRProthrombin3.4.21.50.459
2aot2PMHistamine N-methyltransferase2.1.1.80.459
2b8jADNClass B acid phosphatase3.1.3.20.459
2hzqSTRApolipoprotein D/0.459
2po7CHDFerrochelatase, mitochondrial4.99.1.10.459
2uuk897Prothrombin3.4.21.50.459
2v7tSAH5'-fluoro-5'-deoxy-adenosine synthase/0.459
2wd8VGFPteridine reductase/0.459
2zc922UProthrombin3.4.21.50.459
3af3GCPPantothenate kinase2.7.1.330.459
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.459
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3t0kDCQSulfide-quinone reductase/0.459
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4cb629RPolymerase basic protein 2/0.459
4kfjFOLDihydrofolate reductase1.5.1.30.459
4kn0MTXFolate receptor beta/0.459
4pabTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.459
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.458
1dx6GNTAcetylcholinesterase3.1.1.70.458
1qjfACSIsopenicillin N synthase1.21.3.10.458
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.458
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
1zrqNAI5,10-methylenetetrahydrofolate reductase1.5.1.200.458
2aj4ANPGalactokinase2.7.1.60.458
2geuCOKPantothenate kinase2.7.1.330.458
2r7nADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.458
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.458
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.458
4cb593GPolymerase basic protein 2/0.458
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.458
4xp1LDPSodium-dependent dopamine transporter/0.458
5cc9DDFDihydrofolate reductase1.5.1.30.458
1eveE20Acetylcholinesterase3.1.1.70.457
1hqtNAPAlcohol dehydrogenase [NADP(+)]1.1.1.20.457
1icqOPD12-oxophytodienoate reductase 11.3.1.420.457
1ktsC24Prothrombin3.4.21.50.457
1qv1CZHObelin/0.457
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.457
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.457
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.457
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.457
2vqoTFGHistone deacetylase 43.5.1.980.457
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.457
3iu7FCDMethionine aminopeptidase 2/0.457
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
4c49HCYCorticosteroid-binding globulin/0.457
4jq3ZOMAldo-keto reductase family 1 member C2/0.457
4stdBFSScytalone dehydratase4.2.1.940.457
1dr4HBIDihydrofolate reductase1.5.1.30.456
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.456
1o6qR17Squalene--hopene cyclase4.2.1.1290.456
1ohjCOPDihydrofolate reductase1.5.1.30.456
1sm4FADFerredoxin--NADP reductase/0.456
1upw444Oxysterols receptor LXR-beta/0.456
1w76GNTAcetylcholinesterase3.1.1.70.456
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
1ygkRRCPyridoxal kinase2.7.1.350.456
2cf8ESHProthrombin3.4.21.50.456
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.456
2gesCOKPantothenate kinase2.7.1.330.456
2vrjNCWBeta-glucosidase A3.2.1.210.456
2xuoTZ4Acetylcholinesterase3.1.1.70.456
2y60M8FIsopenicillin N synthase1.21.3.10.456
3af2ACPPantothenate kinase2.7.1.330.456
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.456
3eq02TSProthrombin3.4.21.50.456
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3q9bB3NAcetylpolyamine amidohydrolase/0.456
4jlm1NNDeoxycytidine kinase2.7.1.740.456
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.456
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1lelBH7Avidin/0.455
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.455
1n5vNOMActVA 6 protein/0.455
1yw9A84Methionine aminopeptidase 2/0.455
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.455
2b07598Tyrosine-protein phosphatase non-receptor type 13.1.3.480.455
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.455
2ha6SCKAcetylcholinesterase3.1.1.70.455
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.455
2yhuWHFPteridine reductase/0.455
2zevIPEGeranylgeranyl pyrophosphate synthase/0.455
2zhe13UProthrombin3.4.21.50.455
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3njoPYVAbscisic acid receptor PYR1/0.455
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3udj092Beta-secretase 13.4.23.460.455
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.455
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.455
4c5oFADPutative monooxygenase/0.455
4j7gTRHPCZA361.3/0.455
4n3l2FNProthrombin3.4.21.50.455
4xczT3QQdtf/0.455
5bn3ADPV-type ATP synthase alpha chain/0.455
5bn3ADPNEQ263/0.455
1gj5130Prothrombin3.4.21.50.454
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.454
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.454
1x8lOXRRetinol dehydratase/0.454
2j3qTFLAcetylcholinesterase3.1.1.70.454
2jl1NAPTriphenylmethane reductase/0.454
2pdiZSTAldose reductase1.1.1.210.454
2vq7NAPPutative flavin-containing monooxygenase/0.454
2y6fM9FIsopenicillin N synthase1.21.3.10.454
2za0MGILactoylglutathione lyase4.4.1.50.454
3bmqAX5Pteridine reductase/0.454
3c3xNAPEugenol synthase 11.1.1.3180.454
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.454
3hggCHDCmeR/0.454
3nxvD2FDihydrofolate reductase1.5.1.30.454
3p2hMTAAcyl-homoserine-lactone synthase/0.454
3qftFADNADPH--cytochrome P450 reductase/0.454
3r43ID8Aldo-keto reductase family 1 member C3/0.454
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.454
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.454
4fal0T0Aldo-keto reductase family 1 member C3/0.454
4jqaID8Aldo-keto reductase family 1 member C2/0.454
4y6gF6FTryptophan synthase alpha chain/0.454
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.454
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.453
1o5gCR9Prothrombin3.4.21.50.453
1oc1ASVIsopenicillin N synthase1.21.3.10.453
1pj7FFODimethylglycine oxidase1.5.3.100.453
1r58AO5Methionine aminopeptidase 2/0.453
1re0AFBADP-ribosylation factor 1/0.453
1re0AFBARF guanine-nucleotide exchange factor 1/0.453
1s7gNADNAD-dependent protein deacylase 2/0.453
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.453
1touB1VFatty acid-binding protein, adipocyte/0.453
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.453
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2e94364Geranylgeranyl pyrophosphate synthase/0.453
2gmvUN8Phosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.453
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.453
2qx7NAPEugenol synthase 11.1.1.3180.453
2xytTC9Soluble acetylcholine receptor/0.453
3cfoGMPDNA-directed DNA polymerase/0.453
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.453
3jt3H4BNitric oxide synthase, brain1.14.13.390.453
3r9fGSUMccE protein/0.453
4a86H35Major pollen allergen Bet v 1-A/0.453
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.453
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4j3mAJ8Tankyrase-22.4.2.300.453
4uugPXGBranched-chain amino acid aminotransferase, putative/0.453
5bv3M7Gm7GpppX diphosphatase3.6.1.590.453
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.453
1dghNDPCatalase1.11.1.60.452
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.452
1gjrFADFerredoxin--NADP reductase1.18.1.20.452
1gtiGTBGlutathione S-transferase P 12.5.1.180.452
1q83TZ5Acetylcholinesterase3.1.1.70.452
2aouCQAHistamine N-methyltransferase2.1.1.80.452
2cn0F25Prothrombin3.4.21.50.452
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.452
2qw8NAPEugenol synthase 11.1.1.3180.452
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
2wzySQXSoluble acetylcholine receptor/0.452
3b9gIMHIAG-nucleoside hydrolase/0.452
3c0zSHHHistone deacetylase 73.5.1.980.452
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.452
3pdtADPMyosin heavy chain kinase A2.7.11.70.452
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
3rl45GPMetallophosphoesterase MPPED23.10.452
3zhvTDWMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.452
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.452
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.452
4b1e6T6Beta-secretase 13.4.23.460.452
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.452
4l1xSTRAldo-keto reductase family 1 member C2/0.452
4relKMPGlycosyltransferase/0.452
5bp9SAHPutative methyltransferase protein/0.452
1c7oPPGHemolysin/0.451
1ja1FMNNADPH--cytochrome P450 reductase/0.451
1kruIPTGalactoside O-acetyltransferase2.3.1.180.451
1qiqACCIsopenicillin N synthase1.21.3.10.451
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.451
1w4lGL8Acetylcholinesterase3.1.1.70.451
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.451
2a4xBLMMitomycin-binding protein/0.451
2ct8MSPMethionine--tRNA ligase6.1.1.100.451
2xufTZ4Acetylcholinesterase3.1.1.70.451
2zgx29UProthrombin3.4.21.50.451
3af4GCPPantothenate kinase2.7.1.330.451
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3nxoD2BDihydrofolate reductase1.5.1.30.451
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.451
4gd9BTNStreptavidin/0.451
4lrhFOLFolate receptor alpha/0.451
4n4v2GYTankyrase-12.4.2.300.451
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.451
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.450
1aqv0HGGlutathione S-transferase P2.5.1.180.450
1d6w00RProthrombin3.4.21.50.450
1dr3HBIDihydrofolate reductase1.5.1.30.450
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1odcA8BAcetylcholinesterase3.1.1.70.450
1pd9CO4Dihydrofolate reductase1.5.1.30.450
1qgzFADFerredoxin--NADP reductase1.18.1.20.450
2a5c8DAAvidin/0.450
2fs4PZ1Renin3.4.23.150.450
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.450
2ohhFMNType A flavoprotein FprA10.450
2qcxPF1Aminopyrimidine aminohydrolase/0.450
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.450
3ewkFADSensory box histidine kinase/response regulator/0.450
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.450
3htjETEbrA repressor/0.450
3lg5BTMEpi-isozizaene synthase4.2.3.370.450
3t31DCQSulfide-quinone reductase/0.450
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.450
4e2yJHZMethyltransferase/0.450
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.450
4hfp15UProthrombin3.4.21.50.450
4j7hTRHPCZA361.3/0.450
4khnXG4DNA-directed DNA polymerase/0.450
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.450
4phlPILPhosphodiesterase/0.450
4psbGA3Cytokinin-specific binding protein/0.450
4pv5CBWLactoylglutathione lyase4.4.1.50.450
4qa2SHHHistone deacetylase 83.5.1.980.450
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.450
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.450
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.449
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.449
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.449
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.449
2fzjDH3Dihydrofolate reductase1.5.1.30.449
2qg2A91Heat shock protein HSP 90-alpha/0.449
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.449
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.449
3gncQQQGlutaryl-CoA dehydrogenase/0.449
3n61H4BNitric oxide synthase, brain1.14.13.390.449
3nu03TUDihydrofolate reductase1.5.1.30.449
3qe2FMNNADPH--cytochrome P450 reductase/0.449
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.449
3w0uHPWLactoylglutathione lyase4.4.1.50.449
3zpqXF5Beta-1 adrenergic receptor/0.449
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.449
4dbuBT9Aldo-keto reductase family 1 member C3/0.449
4f79P53Putative phospho-beta-glucosidase/0.449
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.449
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.449
4p9cDCMDeoxycytidylate deaminase/0.449
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.449
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.449
3uonQNBMuscarinic acetylcholine receptor M2/0.449
1e2jTHMThymidine kinase/0.448
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1jumBERHTH-type transcriptional regulator QacR/0.448
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1p8dCO1Oxysterols receptor LXR-beta/0.448
1uzwCDHIsopenicillin N synthase1.21.3.10.448
1zdwFLVPrenyltransferase/0.448
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.448
2dscAPRADP-sugar pyrophosphatase3.6.1.130.448
2gl0ADNUncharacterized protein/0.448
2gvvDI9Diisopropyl-fluorophosphatase3.1.8.20.448
2qdsMCOMetallo-beta-lactamase type 2/0.448
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.448
3iu9T07Methionine aminopeptidase 2/0.448
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.448
4qa0SHHHistone deacetylase 83.5.1.980.448
5d5bCAUBeta-2 adrenergic receptor/0.448
3ny9JSZBeta-2 adrenergic receptor/0.448
1d3pBT3Prothrombin3.4.21.50.447
1dgbNDPCatalase1.11.1.60.447
1gj4132Prothrombin3.4.21.50.447
1mrqSTRAldo-keto reductase family 1 member C1/0.447
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.447
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.447
1towCRZFatty acid-binding protein, adipocyte/0.447
1u65CP0Acetylcholinesterase3.1.1.70.447
2dvlFADAcyl-CoA dehydrogenase/0.447
2ea4F79Methionine aminopeptidase 2/0.447
2g263LGRenin3.4.23.150.447
2q92B23Methionine aminopeptidase/0.447
2v0mKLNCytochrome P450 3A4/0.447
2xuiTZ5Acetylcholinesterase3.1.1.70.447
2zevB71Geranylgeranyl pyrophosphate synthase/0.447
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.447
3aosJH2Hemolymph juvenile hormone binding protein/0.447
3dz6M8ES-adenosylmethionine decarboxylase proenzyme4.1.1.500.447
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.447
3nwlNDPCatalase1.11.1.60.447
3w5uFADFerredoxin/0.447
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.447
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.447
4zqcF6FTryptophan synthase alpha chain/0.447
1pq944BOxysterols receptor LXR-beta/0.446
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.446
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.446
2cleF6FTryptophan synthase alpha chain/0.446
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2vqbNAPPutative flavin-containing monooxygenase/0.446
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.446
3fsjD7KBenzoylformate decarboxylase4.1.1.70.446
3h4vDVPPteridine reductase 11.5.1.330.446
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4fhd0TTSpore photoproduct lyase/0.446
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.446
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.446
4n1fCZHObelin/0.446
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.446
9mhtSAHModification methylase HhaI2.1.1.370.446
1disBDMDihydrofolate reductase1.5.1.30.445
1drfFOLDihydrofolate reductase1.5.1.30.445
1gaqFADFerredoxin/0.445
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2a8gGNGAvidin/0.445
2gqnBLPCystathionine beta-lyase MetC4.4.1.80.445
2gvcFADThiol-specific monooxygenase1.14.130.445
2hctNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.445
2oacGTBGlutathione S-transferase P 12.5.1.180.445
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.445
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.445
2vqsBVDDeoxynucleoside kinase/0.445
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.445
2zhf49UProthrombin3.4.21.50.445
3ab1FADFerredoxin--NADP reductase1.18.1.20.445
3dr4G4MGDP-perosamine synthase/0.445
3elePLPAminotransferase/0.445
3h3r14HCollagen type IV alpha-3-binding protein/0.445
3is9AC7Gag-Pol polyprotein2.7.7.490.445
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
3r58NPSAldo-keto reductase family 1 member C3/0.445
3r8gIZPAldo-keto reductase family 1 member C3/0.445
3r94FLRAldo-keto reductase family 1 member C3/0.445
3sytNADGlutamine-dependent NAD(+) synthetase6.3.5.10.445
3szfDCQSulfide-quinone reductase/0.445
3vilSA0Beta-glucosidase/0.445
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.445
4bftZVTPantothenate kinase2.7.1.330.445
4bvnP32Beta-1 adrenergic receptor/0.445
4dya0MFNucleoprotein/0.445
4jtpASCRibosome inactivating protein/0.445
4p9dTMPDeoxycytidylate deaminase/0.445
1dggNDPCatalase1.11.1.60.444
1dlsMTXDihydrofolate reductase1.5.1.30.444
1e66HUXAcetylcholinesterase3.1.1.70.444
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1p33MTXPteridine reductase 11.5.1.330.444
1vf2GTXGlutathione S-transferase 32.5.1.180.444
1yc2NADNAD-dependent protein deacylase 2/0.444
1zvlH4BNitric oxide synthase, brain1.14.13.390.444
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.444
2jg7NADAntiquitin/0.444
2r6jNDPEugenol synthase 11.1.1.3180.444
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.444
2xlpNAPPutative flavin-containing monooxygenase/0.444
2xugTZ4Acetylcholinesterase3.1.1.70.444
2yg3FADPutrescine oxidase/0.444
2z4w749Geranylgeranyl pyrophosphate synthase/0.444
3br2DEQHTH-type transcriptional regulator QacR/0.444
3c1kT15Prothrombin3.4.21.50.444
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.444
3cv9VDXVitamin D3 dihydroxylase/0.444
3hl0NADMaleylacetate reductase/0.444
3lzzGDPUncharacterized protein/0.444
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.444
3w4k3LDD-amino-acid oxidase1.4.3.30.444
4b66NAPL-ornithine N(5)-monooxygenase/0.444
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
4rxpDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.444
2ycyP32Beta-1 adrenergic receptor/0.444
3ny8JRZBeta-2 adrenergic receptor/0.444
1cjvFOKAdenylate cyclase type 2/0.443
1cjvFOKAdenylate cyclase type 5/0.443
1ej3CZHAequorin-2/0.443
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.443
1qvtPRLHTH-type transcriptional regulator QacR/0.443
1rpwDIDHTH-type transcriptional regulator QacR/0.443
1st0GTGm7GpppX diphosphatase3.6.1.590.443
1swgBTNStreptavidin/0.443
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.443
2bpoFADNADPH--cytochrome P450 reductase/0.443
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
2gg0U11Methionine aminopeptidase/0.443
2uxoTACHTH-type transcriptional regulator TtgR/0.443
2wm3NFLNmrA-like family domain-containing protein 1/0.443
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.443
3cv6HXSAldo-keto reductase family 1 member C21/0.443
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.443
3h0wN8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.443
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3ojwFMNNADPH--cytochrome P450 reductase/0.443
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.443
4azwSAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.443
4bprFADFerredoxin--NADP reductase1.18.1.20.443
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443
4m0f1YKAcetylcholinesterase3.1.1.70.443
4m6kFOLDihydrofolate reductase1.5.1.30.443
4uohADPNucleoside diphosphate kinase/0.443
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.443
1fmlRTLRetinol dehydratase/0.442
1h42FADFerredoxin--NADP reductase1.18.1.20.442
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.442
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.442
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.442
1s1rNAPAldo-keto reductase family 1 member C3/0.442
1u72MTXDihydrofolate reductase1.5.1.30.442
1w6rGNTAcetylcholinesterase3.1.1.70.442
1z5uCMPClass B acid phosphatase/0.442
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2ckmAA7Acetylcholinesterase3.1.1.70.442
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.442
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
2wb5VGBO-GlcNAcase NagJ/0.442
2yyeAPCSelenide, water dikinase2.7.9.30.442
2zfq45UProthrombin3.4.21.50.442
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.442
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.442
3gusN11Glutathione S-transferase P2.5.1.180.442
3jtaH4BNitric oxide synthase, brain1.14.13.390.442
3rthRTHBeta-secretase 13.4.23.460.442
3zo7K6HMuconolactone Delta-isomerase/0.442
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.442
4bfwZVWPantothenate kinase2.7.1.330.442
4bjcRPBTankyrase-22.4.2.300.442
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.442
4dyb0MHNucleoprotein/0.442
4h9506UDihydrofolate reductase1.5.1.30.442
4iae1DXAlr2278 protein/0.442
4kxjP34Nucleoprotein/0.442
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.442
4rn615UProthrombin3.4.21.50.442
4ug5XFKNitric oxide synthase oxygenase1.14.13.1650.442
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.442
5gcnCOAHAT A1/0.442
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1e1cDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.441
1o2g696Prothrombin3.4.21.50.441
1u70MTXDihydrofolate reductase1.5.1.30.441
1yw7A41Methionine aminopeptidase 2/0.441
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2clfF6FTryptophan synthase alpha chain/0.441
2evmFC2Methionine aminopeptidase/0.441
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.441
2rcwAAIPoly [ADP-ribose] polymerase 12.4.2.300.441
2vd7PD2Lysine-specific demethylase 4A1.14.110.441
2zf051UProthrombin3.4.21.50.441
3d27W29Methionine aminopeptidase/0.441
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.441
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.441
3kr8XAVTankyrase-22.4.2.300.441
3nx2FERFerulic acid decarboxylase/0.441
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4c3yANB3-ketosteroid dehydrogenase/0.441
4kzuA73Tankyrase-22.4.2.300.441
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.441
4pnmNU1Tankyrase-22.4.2.300.441
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
5a4vQUEGlutathione S-transferase F22.5.1.180.441
5d4vYGPUncharacterized protein MJ0489/0.441
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.440
1clqGDPDNA-directed DNA polymerase/0.440
1gawFADFerredoxin/0.440
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.440
1k8zIAGTryptophan synthase alpha chain/0.440
1mvtDTMDihydrofolate reductase1.5.1.30.440
1q23FUAChloramphenicol acetyltransferase2.3.1.280.440
1ve74NPAcylamino-acid-releasing enzyme3.4.19.10.440
2bu5TF1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.440
2evcFC3Methionine aminopeptidase/0.440
2jb4A14Isopenicillin N synthase1.21.3.10.440
2z2w770Wee1-like protein kinase2.7.10.20.440
2z7gEH9Adenosine deaminase3.5.4.40.440
3c3eFO12-phospho-L-lactate transferase/0.440
3cuiX4SExoglucanase/xylanase3.2.1.910.440
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3fu83DMLaccase-11.10.3.20.440
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3hy4N5G5-formyltetrahydrofolate cyclo-ligase6.3.3.20.440
3jt6H4BNitric oxide synthase, brain1.14.13.390.440
4bfsZVSPantothenate kinase2.7.1.330.440
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.440
4mrxCZHObelin/0.440