sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 1.000 | |
| 3t94 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.637 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.537 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.537 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.534 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.530 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.524 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.521 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.521 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.520 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.520 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.518 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.508 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.507 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.504 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.504 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.499 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.497 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.496 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.494 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.493 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.493 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.492 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.491 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.491 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.490 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.489 | |
| 2huv | SAH | Diphthine synthase | / | 0.489 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.489 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.489 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.488 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.487 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.487 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.487 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.486 | |
| 1vce | SAH | Diphthine synthase | / | 0.486 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.486 | |
| 2ejz | SAH | Diphthine synthase | / | 0.485 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.485 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.485 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.484 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.483 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.483 | |
| 4boe | CLR | Japanin | / | 0.483 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.482 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.482 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.482 | |
| 4e2x | TYD | Methyltransferase | / | 0.482 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.481 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.481 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.481 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.480 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.480 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.480 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.479 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.478 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.478 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.478 | |
| 5doz | NDP | JamJ | / | 0.477 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.476 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.476 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.476 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.476 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.476 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.475 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.475 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.474 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.474 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.474 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.474 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.474 | |
| 2owg | SAH | Diphthine synthase | / | 0.473 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.473 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.473 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.473 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.472 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.472 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.472 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.472 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.472 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.472 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.472 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.472 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.471 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.471 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.470 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.470 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.469 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.468 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.468 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.468 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.468 | |
| 1t32 | OHH | Cathepsin G | 3.4.21.20 | 0.467 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.467 | |
| 3cne | FMN | Putative protease I | / | 0.467 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.467 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.467 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.467 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.466 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 2dsh | SAH | Diphthine synthase | / | 0.466 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.465 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.465 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.465 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.465 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.465 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.465 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.465 | |
| 2mm3 | CHO | Gastrotropin | / | 0.464 | |
| 2p6l | SAH | Diphthine synthase | / | 0.464 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2yig | 5EL | Collagenase 3 | 3.4.24 | 0.464 | |
| 3eks | CY9 | Actin-5C | / | 0.464 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.464 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.464 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.464 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.464 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.464 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.463 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.463 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.463 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.463 | |
| 1s7n | COA | Acetyl transferase | / | 0.463 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.463 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.463 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.463 | |
| 4bqu | CLR | Japanin | / | 0.463 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.463 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.462 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.462 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.462 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 3i7i | 518 | Collagenase 3 | 3.4.24 | 0.462 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.462 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.461 | |
| 2e15 | SAH | Diphthine synthase | / | 0.461 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.461 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.461 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3eku | CY9 | Actin-5C | / | 0.461 | |
| 3eld | SFG | Methyltransferase | / | 0.461 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.461 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.461 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.460 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.460 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.460 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.460 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.460 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.459 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.459 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.459 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.459 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.459 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.459 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.459 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.458 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.458 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.458 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.458 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.458 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 3nw3 | MU2 | Peptidoglycan recognition protein 1 | / | 0.458 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.458 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.457 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.457 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.457 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.457 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2e7r | SAH | Diphthine synthase | / | 0.457 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.457 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 3d28 | B34 | Genome polyprotein | 2.7.7.48 | 0.457 | |
| 4ffb | GTP | Tubulin alpha-1 chain | / | 0.457 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.457 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.457 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.457 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.456 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.456 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.456 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.456 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.456 | |
| 2jgs | BTN | Avidin | / | 0.456 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.456 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.456 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.456 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.456 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.456 | |
| 4iji | 99T | Glutathione S-transferase-like protein YibF | / | 0.456 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.456 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.456 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.455 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.455 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2e16 | SAH | Diphthine synthase | / | 0.455 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2p9d | SAH | Diphthine synthase | / | 0.455 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.455 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.455 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.455 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3r95 | ACO | MccE protein | / | 0.455 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.455 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.455 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.455 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.455 | |
| 1jf0 | CZH | Obelin | / | 0.454 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.454 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.454 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.454 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.454 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.454 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.454 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.454 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.454 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.454 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.454 | |
| 3bnk | FMN | Flavoredoxin | / | 0.454 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3r96 | ACO | MccE protein | / | 0.454 | |
| 3t6i | NC8 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.454 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.454 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.454 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.454 | |
| 1eio | GCH | Gastrotropin | / | 0.453 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.453 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 3arn | MSJ | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | 3.6.1.23 | 0.453 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.453 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.453 | |
| 4idn | GNP | Atlastin-1 | 3.6.5 | 0.453 | |
| 4ike | ADP | Adenylate kinase | / | 0.453 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.453 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.452 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.452 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.452 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.452 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.452 | |
| 4v12 | POG | MaoC like domain protein | / | 0.452 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2y3s | TIR | TamL | / | 0.451 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.451 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.451 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.451 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4h49 | L29 | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
| 4ohv | ANP | Protein clpf-1 | / | 0.451 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.451 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.451 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2egs | SAH | Diphthine synthase | / | 0.450 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.450 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.449 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.449 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.449 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.449 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2e08 | SAH | Diphthine synthase | / | 0.449 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.449 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.449 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.449 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3f8w | ADN | Purine nucleoside phosphorylase | / | 0.449 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.449 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4cgg | K5Q | Integrase | / | 0.449 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.449 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.449 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.449 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.448 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2el0 | SAH | Diphthine synthase | / | 0.448 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.448 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 3upi | 0C2 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.448 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.448 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.448 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.447 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.447 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.447 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.447 | |
| 2eeq | SAH | Diphthine synthase | / | 0.447 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2hux | SAH | Diphthine synthase | / | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2pda | TPP | Pyruvate synthase | / | 0.447 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.447 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.447 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.447 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.446 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.446 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.446 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 1z1f | STL | Resveratrol synthase | / | 0.446 | |
| 2e07 | SAH | Diphthine synthase | / | 0.446 | |
| 2e8s | SAH | Diphthine synthase | / | 0.446 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.446 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.446 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.446 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 2xvv | 9DN | Serum albumin | / | 0.446 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 2z71 | PNV | Penicillin acylase | 3.5.1.11 | 0.446 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.446 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.446 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.446 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.446 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.446 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4j7g | TRH | PCZA361.3 | / | 0.446 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.446 | |
| 4tlx | FDA | KtzI | / | 0.446 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.445 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.445 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2pca | SAH | Diphthine synthase | / | 0.445 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.445 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.445 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.445 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.445 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bmp | FMN | Protein NrdI | / | 0.445 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.445 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.444 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2e4n | SAH | Diphthine synthase | / | 0.444 | |
| 2ele | SAH | Diphthine synthase | / | 0.444 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.444 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.444 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.444 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.444 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.444 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.444 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 3hj9 | FMN | Uncharacterized protein | / | 0.444 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.444 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.444 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.444 | |
| 4xr9 | NAD | CalS8 | / | 0.444 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.444 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.443 | |
| 1g6o | ADP | Cag alpha | / | 0.443 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.443 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.443 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.443 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.443 | |
| 3ndj | JHZ | Methyltransferase | / | 0.443 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 4e2d | FMN | Dehydrogenase | / | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.443 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.443 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.443 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.442 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.442 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.442 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.442 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.442 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4jky | ADP | Adenylate kinase | / | 0.442 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.442 | |
| 4n1g | CEI | Obelin | / | 0.442 | |
| 4rel | KMP | Glycosyltransferase | / | 0.442 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.442 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.442 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.442 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.441 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.441 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.441 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.441 | |
| 2dek | SAH | Diphthine synthase | / | 0.441 | |
| 2emr | SAH | Diphthine synthase | / | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.441 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.441 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.441 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.441 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.441 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1ank | ANP | Adenylate kinase | / | 0.440 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1xp8 | AGS | Protein RecA | / | 0.440 | |
| 1zdw | FLV | Prenyltransferase | / | 0.440 | |
| 2egl | SAH | Diphthine synthase | / | 0.440 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.440 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.440 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2pcm | SAH | Diphthine synthase | / | 0.440 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2xvw | 9NR | Serum albumin | / | 0.440 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3b9l | AZZ | Serum albumin | / | 0.440 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.440 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.440 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.440 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.440 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.440 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.440 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4dne | DTB | Streptavidin | / | 0.440 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.440 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.440 | |
| 4tm1 | FDA | KtzI | / | 0.440 |