sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 1.000 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.639 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.591 | |
| 3kme | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.576 | |
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.558 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.548 | |
| 2i47 | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.537 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.526 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.523 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.514 | |
| 3l0t | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.513 | |
| 3l0v | 724 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.512 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.509 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.504 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.499 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.498 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.497 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.488 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.487 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.486 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.485 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.485 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.483 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.483 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.482 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.482 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.482 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.482 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.482 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.481 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.481 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 5a3c | NAD | SIR2 family protein | / | 0.481 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.480 | |
| 5dp2 | NAP | CurF | / | 0.480 | |
| 1fml | RTL | Retinol dehydratase | / | 0.479 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.479 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.478 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.478 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.477 | |
| 2o12 | FMN | Chorismate synthase | / | 0.477 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.477 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.476 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.475 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.475 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.475 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.474 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.474 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.474 | |
| 3u9e | COA | Lmo1369 protein | / | 0.474 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.473 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.473 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.473 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.473 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.473 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.473 | |
| 4uoc | NCN | CinA-like protein | / | 0.473 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.472 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.472 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.472 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.472 | |
| 2e77 | FMN | Lactate oxidase | / | 0.471 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.471 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.470 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.470 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.469 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.469 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.468 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.468 | |
| 3qvi | K95 | HAP protein | / | 0.468 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.467 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.467 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.467 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.467 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.466 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1r2j | FAD | FkbI | / | 0.466 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.465 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.465 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.465 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.465 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.465 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.465 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.465 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.465 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.464 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.464 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.464 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.464 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.464 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.464 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.464 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.464 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.464 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4u7w | NDP | MxaA | / | 0.464 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.464 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.464 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.463 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.463 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.463 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.463 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.463 | |
| 4jic | FMN | GTN Reductase | / | 0.463 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.462 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.462 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.462 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.462 | |
| 4g3q | UD1 | Bifunctional protein GlmU | / | 0.462 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.461 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.461 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.461 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.461 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.461 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.461 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.460 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.460 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.460 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.460 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.460 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.460 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.459 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.459 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 3nbv | ANP | Ketohexokinase | / | 0.459 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.459 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.458 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.458 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.458 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.458 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.458 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.458 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.458 | |
| 3kbz | 2T4 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.458 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.458 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.458 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.458 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.458 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.458 | |
| 5ebu | FMN | Lactate oxidase | / | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.457 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.457 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.457 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 2ejz | SAH | Diphthine synthase | / | 0.457 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.457 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.457 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.457 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3uf6 | COD | Lmo1369 protein | / | 0.457 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.457 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.457 | |
| 4h30 | 0ZD | Macrophage metalloelastase | 3.4.24.65 | 0.457 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.457 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.457 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.456 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.456 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.456 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.456 | |
| 4yqf | GDP | Septin-9 | / | 0.456 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.455 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.455 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.455 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.455 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.455 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.455 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.455 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.455 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.455 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.454 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.454 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.454 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4dja | FAD | (6-4) photolyase | / | 0.454 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.454 | |
| 1bwf | ATF | Glycerol kinase | / | 0.453 | |
| 1e2n | RCA | Thymidine kinase | / | 0.453 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.453 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.453 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.453 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.453 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 2j4d | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.453 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.453 | |
| 3nf8 | CDQ | Gag-Pol polyprotein | / | 0.453 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.453 | |
| 3w2u | ROU | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.453 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.453 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.453 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.453 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.452 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 1tu8 | GTX | Glutathione S-transferase 2 | 2.5.1.18 | 0.452 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.452 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.452 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.452 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.452 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.452 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.452 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.452 | |
| 4qec | NAP | ElxO | / | 0.452 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.451 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 2nli | FMN | Lactate oxidase | / | 0.451 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.451 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.451 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.451 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.451 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.451 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.451 | |
| 4rje | FNR | Lactate oxidase | / | 0.451 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.451 | |
| 5ftf | ADP | TPR domain protein | / | 0.451 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.450 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.450 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.450 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.450 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
| 2y4g | TIR | TamL | / | 0.450 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.450 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3b9l | AZZ | Serum albumin | / | 0.450 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.450 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.450 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.450 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.449 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.449 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.449 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.449 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.449 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.449 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.449 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.449 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2wb2 | FAD | RE11660p | / | 0.449 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.449 | |
| 3fd6 | ADP | Selenide, water dikinase 1 | 2.7.9.3 | 0.449 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.449 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.449 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.448 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.448 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.448 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.448 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.448 | |
| 1thy | UMP | Thymidylate synthase | / | 0.448 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ddy | MDW | Matrilysin | 3.4.24.23 | 0.448 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.448 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.448 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.448 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 3v2u | ATP | Protein GAL3 | / | 0.448 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.448 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.447 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.447 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.447 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.447 | |
| 1skg | VAL_ALA_PHE_ARG_SER | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.447 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2ab8 | ACP | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.447 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.447 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.447 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.447 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.447 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.447 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 3e8r | 615 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.447 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.447 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.447 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4l4x | NDP | AmphI | / | 0.447 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.447 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.446 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.446 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.446 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.446 | |
| 2fna | ADP | Uncharacterized protein | / | 0.446 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.446 | |
| 2owk | SAH | Diphthine synthase | / | 0.446 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.446 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.446 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.446 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.446 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.446 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.446 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.446 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.446 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.446 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.445 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.445 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.445 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.445 | |
| 1uam | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2ehl | SAH | Diphthine synthase | / | 0.445 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.445 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.445 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.445 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.445 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.445 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.445 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.445 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.445 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.445 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.445 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.445 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.445 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.445 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.445 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.444 | |
| 1g9d | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.444 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 2bxm | IMN | Serum albumin | / | 0.444 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.444 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.444 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.444 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.444 | |
| 2srt | INH | Stromelysin-1 | 3.4.24.17 | 0.444 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.444 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.444 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.444 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.444 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.444 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.444 | |
| 3w1r | MRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.444 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.444 | |
| 4y0k | NAP | AntE | / | 0.444 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.444 | |
| 5a3b | APR | SIR2 family protein | / | 0.444 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.443 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.443 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.443 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.443 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.443 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.443 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.443 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.443 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.443 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.443 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.443 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.443 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.442 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.442 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.442 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.442 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3gag | FMN | Putative NADH dehydrogenase NAD(P)H nitroreductase | / | 0.442 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.442 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.442 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.442 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4ybr | NAP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.442 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.442 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.441 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.441 | |
| 1l9k | SAH | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.441 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.441 | |
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 0.441 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.441 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.441 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.441 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.441 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.441 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.441 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.441 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.441 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.441 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.441 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.440 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.440 | |
| 1vce | SAH | Diphthine synthase | / | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.440 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.440 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.440 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.440 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.440 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.440 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.440 | |
| 4f09 | JAK | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.440 | |
| 4mcb | 21W | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4umx | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 |