sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.761 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.707 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.681 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.665 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.657 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.653 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.651 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.649 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.647 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.640 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.637 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.635 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.629 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.620 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.617 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.615 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.613 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.605 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.596 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.590 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.587 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.586 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.583 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.576 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.575 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.572 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.571 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.568 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.564 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.563 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.562 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.560 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.557 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.554 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.553 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.549 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.546 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.539 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.534 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.529 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.517 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.515 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.506 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.495 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.476 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.475 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.472 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.471 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.468 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.464 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.463 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.461 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.461 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.457 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.456 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.454 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.454 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.453 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.452 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.452 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.449 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.449 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.446 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.443 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.442 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 |