sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 1.000 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 1.000 | |
| 3ae4 | N1M | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.565 | |
| 3ae4 | N1M | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.565 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.551 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.551 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.548 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.548 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.534 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.505 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.502 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.500 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.496 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.491 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.489 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.489 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.488 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.488 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.486 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.486 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.486 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.485 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.484 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.484 | |
| 1r2j | FAD | FkbI | / | 0.484 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.484 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.484 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.484 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.483 | |
| 4hxy | NDP | Plm1 | / | 0.483 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.482 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.481 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.481 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.480 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.480 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.479 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.478 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.478 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.477 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.477 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.477 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.477 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.477 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.477 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.477 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.477 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.476 | |
| 4okw | 198 | Androgen receptor | / | 0.476 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.475 | |
| 3v49 | PK0 | Androgen receptor | / | 0.475 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.475 | |
| 1osv | CHC | Bile acid receptor | / | 0.474 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.474 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.474 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.473 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.473 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.473 | |
| 2xvv | 9DN | Serum albumin | / | 0.473 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.473 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.473 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.472 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.471 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.470 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.470 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.470 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.470 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.470 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.470 | |
| 4xvr | GNP | GTPase HRas | / | 0.470 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1v4s | MRK | Glucokinase | 2.7.1.2 | 0.469 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.469 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.469 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.468 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.468 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.468 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.468 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.467 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.467 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.467 | |
| 3b9l | AZZ | Serum albumin | / | 0.467 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.467 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.467 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.467 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.466 | |
| 2bxq | IMN | Serum albumin | / | 0.466 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.466 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.466 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.466 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.466 | |
| 4irn | FAD | AnaB | / | 0.466 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.466 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1til | ATP | Anti-sigma F factor | / | 0.465 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.465 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.465 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.464 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.464 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.463 | |
| 1zdw | FLV | Prenyltransferase | / | 0.463 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.463 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.463 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.463 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.463 | |
| 2y3s | TIR | TamL | / | 0.463 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 4okx | 198 | Androgen receptor | / | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.462 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.462 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.462 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.462 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4jld | ADP | Adenylate kinase | / | 0.462 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.462 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.461 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.461 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.461 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.461 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.461 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.461 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.460 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.460 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.460 | |
| 2ejz | SAH | Diphthine synthase | / | 0.460 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.460 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.460 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.460 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.460 | |
| 4ojb | 198 | Androgen receptor | / | 0.460 | |
| 4pd6 | URI | Nucleoside permease | / | 0.460 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.459 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.459 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.459 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.459 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.459 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.459 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.459 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.458 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.458 | |
| 4okb | 198 | Androgen receptor | / | 0.458 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.457 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.457 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.457 | |
| 3dol | GWI | Pol protein | / | 0.457 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.457 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.457 | |
| 3pn1 | IVH | DNA ligase | / | 0.457 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5doz | NDP | JamJ | / | 0.457 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.456 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.456 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.456 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.456 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.455 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1yin | CM3 | Estrogen receptor | / | 0.455 | |
| 2eeq | SAH | Diphthine synthase | / | 0.455 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.455 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.455 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.455 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3lpf | Z77 | Beta-glucuronidase | 3.2.1.31 | 0.455 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.455 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.455 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.455 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.455 | |
| 5a3b | APR | SIR2 family protein | / | 0.455 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.455 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.454 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.454 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.454 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.454 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.454 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.454 | |
| 1eio | GCH | Gastrotropin | / | 0.453 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.453 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.453 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.453 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.453 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.453 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.453 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.453 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.451 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.451 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2e15 | SAH | Diphthine synthase | / | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.451 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3eej | 53R | Uncharacterized protein | / | 0.451 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.451 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.451 | |
| 4jky | ADP | Adenylate kinase | / | 0.451 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4lb2 | DM5 | Serum albumin | / | 0.451 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.451 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.451 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.451 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.450 | |
| 2p2x | SAH | Diphthine synthase | / | 0.450 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.450 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.450 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.450 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.450 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.450 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.450 | |
| 4coj | DTP | Uncharacterized protein | / | 0.450 | |
| 4iah | 1DX | Alr2278 protein | / | 0.450 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2dxv | SAH | Diphthine synthase | / | 0.449 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.449 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.449 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.449 | |
| 3moh | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.449 | |
| 3ue6 | FMN | Aureochrome1 | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.449 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.449 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.449 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.449 | |
| 4iak | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.449 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.449 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.449 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.449 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.449 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.448 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.448 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.448 | |
| 1wng | SAH | Diphthine synthase | / | 0.448 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.448 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.448 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.448 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 3dok | GWJ | Pol protein | / | 0.448 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3iaa | TYD | CalG2 | / | 0.448 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.448 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.448 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.448 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.448 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.448 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.448 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.448 | |
| 4xt5 | NAP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.448 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.447 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.447 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2dsg | SAH | Diphthine synthase | / | 0.447 | |
| 2egl | SAH | Diphthine synthase | / | 0.447 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.447 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.447 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.447 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.447 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.447 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 4e2b | FMN | Dehydrogenase | / | 0.447 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.447 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.447 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.447 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.447 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.446 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.446 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.446 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.446 | |
| 1q13 | TES | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.446 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2hux | SAH | Diphthine synthase | / | 0.446 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.446 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.446 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.446 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.446 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.446 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4iae | 1DX | Alr2278 protein | / | 0.446 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4up3 | NDP | Thioredoxin reductase | / | 0.446 | |
| 4yry | NAD | Glutamate synthase, beta subunit | / | 0.446 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.445 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.445 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2acw | UPG | Glycosyltransferase | / | 0.445 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2dsh | SAH | Diphthine synthase | / | 0.445 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.445 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.445 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.445 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.445 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.445 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.445 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.445 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.445 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.444 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.444 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.444 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.444 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.444 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.444 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.444 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.444 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.444 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3t58 | FAD | Sulfhydryl oxidase 1 | 1.8.3.2 | 0.444 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.444 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4ike | ADP | Adenylate kinase | / | 0.444 | |
| 4o4i | ACP | Tubulin tyrosine ligase | / | 0.444 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.443 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 1x14 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 1yrx | FMN | AppA protein | / | 0.443 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.443 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.443 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.443 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 2xvw | 9NR | Serum albumin | / | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.443 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.443 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.443 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.442 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hlk | 113 | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 1l0o | ADP | Anti-sigma F factor | / | 0.442 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.442 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.442 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.442 | |
| 2huv | SAH | Diphthine synthase | / | 0.442 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.442 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.442 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.442 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.442 | |
| 3ely | SAH | Methyltransferase | / | 0.442 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.442 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.442 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.442 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.442 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.442 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.442 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.442 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4e2d | FMN | Dehydrogenase | / | 0.442 | |
| 4jl6 | ADP | Adenylate kinase | / | 0.442 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.442 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.442 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.441 | |
| 1fjx | SAH | Modification methylase HhaI | 2.1.1.37 | 0.441 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.441 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.441 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.441 | |
| 2eka | SAH | Diphthine synthase | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.441 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3eld | SFG | Methyltransferase | / | 0.441 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.441 | |
| 4py2 | 43E | Methionine--tRNA ligase | / | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5ftc | ADP | TPR domain protein | / | 0.441 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.440 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.440 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.440 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.440 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.440 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.440 | |
| 2e8h | SAH | Diphthine synthase | / | 0.440 | |
| 2egb | SAH | Diphthine synthase | / | 0.440 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2v0u | FMN | NPH1-1 | / | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.440 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.440 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.440 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 3v4a | PK1 | Androgen receptor | / | 0.440 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.440 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4e5m | NAP | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.440 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4hz5 | 19Y | DNA topoisomerase 4 subunit B | / | 0.440 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.440 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.440 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.440 |