sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1z89 | 62P | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.801 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.783 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.766 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.766 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.709 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.703 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.690 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.680 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.680 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.674 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.670 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.667 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.663 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.656 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.653 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.651 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.647 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.637 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.629 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.624 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.623 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.617 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.612 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.611 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.607 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.603 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.601 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.598 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.595 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.595 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.594 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.593 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.592 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.591 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.591 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.590 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.589 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.587 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.582 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.578 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.573 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.572 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.571 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.571 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.570 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.556 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.555 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.553 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.547 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.545 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.530 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.524 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.523 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.516 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.511 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.508 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.506 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.506 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.500 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.499 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.498 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.496 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.494 | |
| 4xwt | U5P | Ribonuclease J | / | 0.491 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.489 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.487 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.486 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.484 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.480 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.479 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.478 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.478 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.478 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.477 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.476 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.475 | |
| 4phl | PIL | Phosphodiesterase | / | 0.475 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.473 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.473 | |
| 1rxj | BNI | Streptavidin | / | 0.471 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.470 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.470 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.470 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.469 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.469 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.468 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.468 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.466 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.466 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1fml | RTL | Retinol dehydratase | / | 0.465 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.465 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.465 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.464 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.463 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.462 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.462 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.461 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.461 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.461 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.460 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 1c7o | PPG | Hemolysin | / | 0.459 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.459 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.459 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.459 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.459 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.458 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.458 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.458 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4kmz | FOL | Folate receptor beta | / | 0.457 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.456 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.454 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.453 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.452 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.452 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.452 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.452 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.452 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.451 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.451 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.450 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.450 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.450 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.450 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.449 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.448 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.448 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.447 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.447 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.447 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 3pn1 | IVH | DNA ligase | / | 0.447 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.447 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.446 | |
| 1s36 | CEI | Obelin | / | 0.446 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.446 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.445 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.445 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.444 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.444 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 2hzq | STR | Apolipoprotein D | / | 0.443 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3klb | FMN | Uncharacterized protein | / | 0.443 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.443 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4nqg | CZH | Mitrocomin | / | 0.443 | |
| 4yfy | 0FX | VioF | / | 0.443 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.442 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.442 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2ok7 | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.441 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.441 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.441 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.441 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.441 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.441 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.441 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.441 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.440 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.440 |