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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1yv5RISFarnesyl pyrophosphate synthase2.5.1.10

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1yv5RISFarnesyl pyrophosphate synthase2.5.1.101.000
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.654
3ldwZOLFarnesyl pyrophosphate synthase, putative/0.574
4q23RISFarnesyl pyrophosphate synthase2.5.1.100.573
4nkeRISFarnesyl pyrophosphate synthase2.5.1.100.546
2i191BYFarnesyl pyrophosphate synthase/0.535
3rbmB73Farnesyl pyrophosphate synthase, putative/0.527
2f94BFQFarnesyl pyrophosphate synthase2.5.1.100.519
4lfgIPEPutative geranyltranstransferase/0.456
3ez3IPEFarnesyl pyrophosphate synthase, putative/0.450
4kqsRISFarnesyl pyrophosphate synthase2.5.1.100.445