sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1yu9 | GNP | Ras-related protein Rab-4A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 1.000 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.606 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.600 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.582 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.582 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.579 | |
| 3tgp | GNP | GTPase HRas | / | 0.575 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.572 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.571 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.570 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.567 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.567 | |
| 3lbn | GNP | GTPase HRas | / | 0.567 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.566 | |
| 3lbh | GNP | GTPase HRas | / | 0.560 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.558 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.555 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.553 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.552 | |
| 3oiv | GNP | GTPase HRas | / | 0.552 | |
| 4l9s | GDP | GTPase HRas | / | 0.552 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.551 | |
| 3k8y | GNP | GTPase HRas | / | 0.551 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.550 | |
| 2rgg | GNP | GTPase HRas | / | 0.548 | |
| 3l8y | GNP | GTPase HRas | / | 0.548 | |
| 3v4f | GNP | GTPase HRas | / | 0.547 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.547 | |
| 4dlt | GNP | GTPase HRas | / | 0.547 | |
| 4dsn | GCP | GTPase KRas | / | 0.546 | |
| 4g0n | GNP | GTPase HRas | / | 0.544 | |
| 3oiw | GNP | GTPase HRas | / | 0.542 | |
| 4ql3 | GDP | GTPase KRas | / | 0.541 | |
| 3oiu | GNP | GTPase HRas | / | 0.540 | |
| 4tq9 | GDP | GTPase KRas | / | 0.540 | |
| 4q03 | GDP | GTPase KRas | / | 0.538 | |
| 4xvr | GNP | GTPase HRas | / | 0.536 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.535 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.535 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.535 | |
| 2ce2 | GDP | GTPase HRas | / | 0.533 | |
| 2rge | GNP | GTPase HRas | / | 0.533 | |
| 3lbi | GNP | GTPase HRas | / | 0.532 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.532 | |
| 3rs4 | GNP | GTPase HRas | / | 0.531 | |
| 5b2z | GNP | GTPase HRas | / | 0.531 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.529 | |
| 2rgc | GNP | GTPase HRas | / | 0.529 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.528 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.528 | |
| 4epx | GDP | GTPase KRas | / | 0.528 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.527 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.526 | |
| 4nyi | GNP | GTPase HRas | / | 0.526 | |
| 4xvq | GNP | GTPase HRas | / | 0.526 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.525 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.524 | |
| 4k81 | GTP | GTPase HRas | / | 0.524 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.523 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.522 | |
| 4luc | GDP | GTPase KRas | / | 0.521 | |
| 3ddc | GNP | GTPase HRas | / | 0.518 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.517 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.517 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.516 | |
| 2c5l | GTP | GTPase HRas | / | 0.516 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.516 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.516 | |
| 4lpk | GDP | GTPase KRas | / | 0.516 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.515 | |
| 4obe | GDP | GTPase KRas | / | 0.515 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.513 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.513 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.512 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.512 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.512 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.510 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.510 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.509 | |
| 3rs7 | GNP | GTPase HRas | / | 0.509 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.509 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.508 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.507 | |
| 3k9l | GNP | GTPase HRas | / | 0.507 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.507 | |
| 3rs5 | GNP | GTPase HRas | / | 0.507 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.507 | |
| 4wa7 | GDP | GTPase KRas | / | 0.507 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.506 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.505 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.505 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.504 | |
| 3i3s | GNP | GTPase HRas | / | 0.504 | |
| 4epw | GDP | GTPase KRas | / | 0.504 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.503 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.500 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.499 | |
| 4ldj | GDP | GTPase KRas | / | 0.499 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.498 | |
| 4lv6 | GDP | GTPase KRas | / | 0.498 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.496 | |
| 4l8g | GDP | GTPase KRas | / | 0.496 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.496 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.495 | |
| 4q02 | GDP | GTPase KRas | / | 0.495 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.494 | |
| 3rs0 | GNP | GTPase HRas | / | 0.492 | |
| 4mit | GTP | Rho-related protein racC | / | 0.491 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.489 | |
| 4dlx | GNP | GTPase HRas | / | 0.489 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.488 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.486 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.486 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.485 | |
| 2rgb | GNP | GTPase HRas | / | 0.485 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.485 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.484 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.484 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.484 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.482 | |
| 2cl6 | CAG | GTPase HRas | / | 0.482 | |
| 4dlw | GNP | GTPase HRas | / | 0.482 | |
| 4dls | GNP | GTPase HRas | / | 0.480 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.479 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.479 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.478 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.477 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.477 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.477 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.476 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.475 | |
| 2gn4 | UD1 | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.475 | |
| 4dlz | GNP | GTPase HRas | / | 0.475 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.474 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.474 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.474 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.474 | |
| 3ref | GDP | Rho family GTPase | / | 0.474 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.473 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.473 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.473 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.473 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.472 | |
| 4g01 | GDP | Ras-related protein RABF2b | / | 0.472 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.471 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.471 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.471 | |
| 4lrw | GDP | GTPase KRas | / | 0.471 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.471 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.470 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.470 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.470 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.469 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.469 | |
| 4nyj | GNP | GTPase HRas | / | 0.469 | |
| 4tnx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.469 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.468 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.468 | |
| 4dlv | GNP | GTPase HRas | / | 0.468 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.467 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.467 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.466 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.466 | |
| 4l9w | GNP | GTPase HRas | / | 0.466 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.465 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.464 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.464 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.463 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.463 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.463 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.463 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.463 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.462 | |
| 2y3r | TRK | TamL | / | 0.462 | |
| 4ys0 | ADP | Protein translocase subunit SecA | / | 0.462 | |
| 1khe | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.461 | |
| 1wdt | GTP | Elongation factor G (EF-G-2) | / | 0.461 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.461 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.460 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.460 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.459 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.459 | |
| 5ftc | ADP | TPR domain protein | / | 0.459 | |
| 1osv | CHC | Bile acid receptor | / | 0.458 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.458 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.458 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.457 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.457 | |
| 3up0 | D7S | aceDAF-12 | / | 0.457 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 5iot | UMP | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.457 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.456 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.456 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.455 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.454 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.454 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.454 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.454 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.454 | |
| 1lfd | GNP | GTPase HRas | / | 0.453 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.453 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.453 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.453 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.453 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.453 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.453 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.452 | |
| 2hpt | BES | Aminopeptidase N | 3.4.11.2 | 0.452 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.452 | |
| 3wyg | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.452 | |
| 4dsu | GDP | GTPase KRas | / | 0.452 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4nu0 | AP5 | Adenylate kinase | / | 0.452 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.451 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.451 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.451 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.451 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.451 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.451 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.450 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.450 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.450 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.450 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.450 | |
| 3kai | 4FI | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 5.2.1.8 | 0.450 | |
| 3r9x | GNP | GTPase Era | / | 0.450 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.450 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.449 | |
| 3rha | FDA | Putrescine oxidase | / | 0.449 | |
| 3rsl | GNP | GTPase HRas | / | 0.449 | |
| 4iij | GTP | Tubulin alpha-1B chain | / | 0.449 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.449 | |
| 4tnp | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.448 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.448 | |
| 4iwy | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.448 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.448 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.447 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.447 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.447 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.447 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.447 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.447 | |
| 3jq3 | ADP | Lombricine kinase | / | 0.447 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.447 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.447 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.447 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.446 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.446 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.446 | |
| 2gr2 | APR | Ferredoxin reductase | / | 0.446 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.446 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.446 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.446 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.446 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.445 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.445 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.445 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.445 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.445 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.445 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.445 | |
| 4gql | R47 | Macrophage metalloelastase | 3.4.24.65 | 0.445 | |
| 4zwg | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.444 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.444 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.444 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.444 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.444 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.443 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.443 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.443 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.443 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.443 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.442 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.442 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.442 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.442 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.442 | |
| 3hpq | AP5 | Adenylate kinase | / | 0.442 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.442 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.442 | |
| 4dso | GSP | GTPase KRas | / | 0.442 | |
| 4e2b | FMN | Dehydrogenase | / | 0.442 | |
| 4r43 | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.442 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.442 | |
| 5l3s | GNP | Signal recognition particle receptor FtsY | / | 0.442 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.441 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.441 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.441 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.441 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4ike | ADP | Adenylate kinase | / | 0.441 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.440 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.440 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.440 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.440 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4tm0 | NAP | KtzI | / | 0.440 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.440 | |
| 5l3r | GCP | Cell division protein FtsY homolog, chloroplastic | / | 0.440 |