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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.11.000
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.724
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.657
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.648
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.643
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.641
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.641
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.641
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.640
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.630
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.630
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.630
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.628
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.626
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.623
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.623
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.619
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.614
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.613
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.611
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.610
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.608
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.608
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.607
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.606
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.606
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.600
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.599
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.595
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.588
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.588
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.587
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.587
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.576
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.574
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.574
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.574
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.571
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.567
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.566
3iw4LW4Protein kinase C alpha type2.7.11.130.565
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.561
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.561
2jedLG8Protein kinase C theta type2.7.11.130.554
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.550
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.547
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.540
4othDRNSerine/threonine-protein kinase N1/0.537
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.535
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
3umw596Serine/threonine-protein kinase pim-12.7.11.10.530
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.530
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.524
3a4pDFQHepatocyte growth factor receptor2.7.10.10.524
4dymIYZActivin receptor type-12.7.11.300.524
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.521
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.520
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.517
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.513
4jq8KJ8Epidermal growth factor receptor2.7.10.10.513
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.510
4bchT7ZCyclin-dependent kinase 92.7.11.220.508
4bgg844Activin receptor type-12.7.11.300.506
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.505
1xjdSTUProtein kinase C theta type2.7.11.130.503
4i22IREEpidermal growth factor receptor2.7.10.10.503
1zys199Serine/threonine-protein kinase Chk12.7.11.10.501
4yuqKS1Calmodulin-like domain protein kinase/0.501
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.500
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.500
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2uxpCLMHTH-type transcriptional regulator TtgR/0.498
4gg70J8Hepatocyte growth factor receptor2.7.10.10.496
4hnf16WCasein kinase I isoform delta2.7.11.10.496
4gmy0X5Tyrosine-protein kinase JAK2/0.492
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.491
4hni16WCasein kinase I isoform epsilon2.7.11.10.491
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.490
3mtfA3FActivin receptor type-12.7.11.300.490
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.490
3t8oATPRhodopsin kinase/0.490
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.490
3du8553Glycogen synthase kinase-3 beta2.7.11.260.489
3oom507Activin receptor type-12.7.11.300.489
3bu5ATPInsulin receptor2.7.10.10.487
1h1s4SPCyclin-dependent kinase 22.7.11.220.486
2ittAEEEpidermal growth factor receptor2.7.10.10.486
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.486
3uyt0CKCasein kinase I isoform delta2.7.11.10.486
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.486
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.486
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.485
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.485
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.484
1wvxBD4Death-associated protein kinase 12.7.11.10.483
2ckeIQUDeath-associated protein kinase 2/0.483
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.483
1aq1STUCyclin-dependent kinase 22.7.11.220.481
3gu6ADPDeath-associated protein kinase 12.7.11.10.481
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.481
4bbe3O4Tyrosine-protein kinase JAK2/0.481
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.481
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.479
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.478
4jr3KJREpidermal growth factor receptor2.7.10.10.478
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.477
3blrCPBCyclin-dependent kinase 92.7.11.220.477
3bqr4RBDeath-associated protein kinase 3/0.477
3gc9B45Mitogen-activated protein kinase 112.7.11.240.477
3gubGUBDeath-associated protein kinase 12.7.11.10.477
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.477
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.476
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.476
3a60STURibosomal protein S6 kinase beta-12.7.11.10.475
4jq7KJQEpidermal growth factor receptor2.7.10.10.475
5f0a1FBcGMP-dependent protein kinase, putative/0.475
2j0k4STFocal adhesion kinase 12.7.10.20.474
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.474
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.474
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.474
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.473
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.473
4fob0USALK tyrosine kinase receptor2.7.10.10.473
5auvAGIDeath-associated protein kinase 12.7.11.10.473
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.472
4fnyI3KALK tyrosine kinase receptor2.7.10.10.472
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.471
1zgaHMKIsoflavone 4'-O-methyltransferase/0.471
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3mvl38PMitogen-activated protein kinase 14/0.471
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.471
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.470
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
5auwQUEDeath-associated protein kinase 12.7.11.10.470
3c4xATPRhodopsin kinase/0.469
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.469
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.468
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.468
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.467
3sheI85MAP kinase-activated protein kinase 32.7.11.10.467
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.467
4wboANWRhodopsin kinase/0.467
2hog710Serine/threonine-protein kinase Chk12.7.11.10.466
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.466
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.466
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.466
1eh4IC1Casein kinase I homolog 12.7.11.10.465
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.465
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.465
1oiyN41Cyclin-dependent kinase 22.7.11.220.464
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2iw84SPCyclin-dependent kinase 22.7.11.220.464
2vagV25Dual specificity protein kinase CLK12.7.12.10.464
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.464
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.464
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.464
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.464
4grb0XGCasein kinase II subunit alpha2.7.11.10.464
1oguST8Cyclin-dependent kinase 22.7.11.220.463
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.463
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.463
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.463
4aacAAVMitogen-activated protein kinase 14/0.462
4jrvKJVEpidermal growth factor receptor2.7.10.10.462
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.461
2izrBRKCasein kinase I isoform gamma-32.7.11.10.461
2izt23DCasein kinase I isoform gamma-32.7.11.10.461
3c50ADPRhodopsin kinase/0.461
3gxlQIGTGF-beta receptor type-12.7.11.300.461
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.461
4iaq2GM5-hydroxytryptamine receptor 1B/0.461
2acxANPG protein-coupled receptor kinase 62.7.11.160.460
2wpa889Cyclin-dependent kinase 22.7.11.220.460
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.460
4dgnLU2Casein kinase II subunit alpha2.7.11.10.460
1m17AQ4Epidermal growth factor receptor2.7.10.10.459
2izuP01Casein kinase I isoform gamma-32.7.11.10.459
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.459
4gu610NFocal adhesion kinase 12.7.10.20.459
4ic7ANPMitogen-activated protein kinase 72.7.11.240.459
4kbk1QGCasein kinase I isoform delta2.7.11.10.459
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.459
4ubsDIFPentalenic acid synthase1.14.15.110.459
1k6tXN1Gag-Pol polyprotein3.4.23.160.458
1oi9N20Cyclin-dependent kinase 22.7.11.220.458
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.458
1ywrLI9Mitogen-activated protein kinase 14/0.458
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.458
2chlDKICasein kinase I isoform gamma-32.7.11.10.458
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
3kf7L9GMitogen-activated protein kinase 14/0.458
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.458
4xlvACPInsulin receptor2.7.10.10.458
5auxKMPDeath-associated protein kinase 12.7.11.10.458
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.457
2i0ePDSProtein kinase C beta type2.7.11.130.457
2wihP48Cyclin-dependent kinase 22.7.11.220.457
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.457
3zze6XPHepatocyte growth factor receptor2.7.10.10.457
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.457
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.457
1klkPMDDihydrofolate reductase1.5.1.30.456
2j0lANPFocal adhesion kinase 12.7.10.20.456
2j0m4STFocal adhesion kinase 12.7.10.20.456
3zh8C58Protein kinase C iota type2.7.11.130.456
1h1r6CPCyclin-dependent kinase 22.7.11.220.455
1qxlFR8Adenosine deaminase3.5.4.40.455
3q9xEMOCasein kinase II subunit alpha2.7.11.10.455
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.455
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.455
4eor4SPCyclin-dependent kinase 22.7.11.220.455
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.455
4hgt15GCasein kinase I isoform delta2.7.11.10.455
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.455
4qmzB49Serine/threonine-protein kinase 242.7.11.10.455
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.454
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.454
2itpAEEEpidermal growth factor receptor2.7.10.10.454
2x1nX1NCyclin-dependent kinase 22.7.11.220.454
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.454
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.454
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.453
2itqITQEpidermal growth factor receptor2.7.10.10.453
2pulACPMethylthioribose kinase2.7.1.1000.453
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.453
3ddpRC8Cyclin-dependent kinase 22.7.11.220.453
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.453
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.453
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.453
5cvhADPCasein kinase II subunit alpha2.7.11.10.453
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.452
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.452
2bujSTUSerine/threonine-protein kinase 16/0.452
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.452
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.452
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.452
1k7fIAVTryptophan synthase alpha chain/0.451
1oiuN76Cyclin-dependent kinase 22.7.11.220.451
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.451
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.451
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.451
2wkmPFYHepatocyte growth factor receptor2.7.10.10.451
2xikJ60Serine/threonine-protein kinase 252.7.11.10.451
3lltANPProtein serine/threonine kinase-1/0.451
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.451
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.451
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.451
4gg50J3Hepatocyte growth factor receptor2.7.10.10.451
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1yvj4STTyrosine-protein kinase JAK32.7.10.20.450
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.450
2c7xNRBCytochrome P450 monooxygenase PikC/0.450
2etm7PYFocal adhesion kinase 12.7.10.20.450
2iw94SPCyclin-dependent kinase 22.7.11.220.450
2j0j4STFocal adhesion kinase 12.7.10.20.450
3a7jADPSerine/threonine-protein kinase 242.7.11.10.450
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.450
3oqfS51Renin3.4.23.150.450
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.450
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4b99R4LMitogen-activated protein kinase 72.7.11.240.450
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.450
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.450
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.449
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.449
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.449
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.449
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.449
4kb81QNCasein kinase I isoform delta2.7.11.10.449
4nc3ERM5-hydroxytryptamine receptor 2B/0.449
1u54ACPActivated CDC42 kinase 1/0.448
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2ojg19AMitogen-activated protein kinase 12.7.11.240.448
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.448
4g170VNCasein kinase I isoform gamma-32.7.11.10.448
4iarERM5-hydroxytryptamine receptor 1B/0.448
4ib4ERM5-hydroxytryptamine receptor 2B/0.448
4jia1K3Tyrosine-protein kinase JAK2/0.448
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.448
4riyADPEpidermal growth factor receptor2.7.10.10.448
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.447
2ghmLICMitogen-activated protein kinase 14/0.447
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.447
2wecPP5Penicillopepsin-13.4.23.200.447
2x7gPVBSRSF protein kinase 22.7.11.10.447
3ormAGSSerine/threonine protein kinase/0.447
3qu0X40Cyclin-dependent kinase 22.7.11.220.447
3w2sW2REpidermal growth factor receptor2.7.10.10.447
4bcoT6QCyclin-dependent kinase 22.7.11.220.447
4bcqTJFCyclin-dependent kinase 22.7.11.220.447
4erwSTUCyclin-dependent kinase 22.7.11.220.447
4kba1QMCasein kinase I isoform delta2.7.11.10.447
1ndzFR5Adenosine deaminase3.5.4.40.446
1p4fDRGDeath-associated protein kinase 12.7.11.10.446
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.446
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.446
2izsBRQCasein kinase I isoform gamma-32.7.11.10.446
2wedPP6Penicillopepsin-13.4.23.200.446
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.446
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.446
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.446
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.446
4c4h7RODual specificity protein kinase TTK2.7.12.10.446
4e730NRMitogen-activated protein kinase 82.7.11.240.446
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.446
4hvh19RTyrosine-protein kinase JAK32.7.10.20.446
1bxoPP7Penicillopepsin-13.4.23.200.445
1x8lOXRRetinol dehydratase/0.445
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.445
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.445
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.445
3igoANPCalmodulin-domain protein kinase 1, putative/0.445
3pe2E1BCasein kinase II subunit alpha2.7.11.10.445
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.445
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4j95ACPFibroblast growth factor receptor 2/0.445
1u4dDBQActivated CDC42 kinase 1/0.444
1umlFR4Adenosine deaminase3.5.4.40.444
1vjy460TGF-beta receptor type-12.7.11.300.444
2b52D42Cyclin-dependent kinase 22.7.11.220.444
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2uzlC94Cyclin-dependent kinase 22.7.11.220.444
2wxvWXVCyclin-dependent kinase 22.7.11.220.444
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.444
3k47D09Dihydrofolate reductase1.5.1.30.444
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.444
3u4uLNHCasein kinase II subunit alpha2.7.11.10.444
4aa5NQBMitogen-activated protein kinase 14/0.444
4fx360KCyclin-dependent kinase 22.7.11.220.444
4ryvZEAProtein LlR18A/0.444
5e8wSTUTGF-beta receptor type-12.7.11.300.444
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1bygSTUTyrosine-protein kinase CSK/0.443
2ca0PXICytochrome P450 monooxygenase PikC/0.443
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.443
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2vu3LZECyclin-dependent kinase 22.7.11.220.443
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.443
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4f640S8Fibroblast growth factor receptor 1/0.443
4ih8B43Calmodulin-domain protein kinase 1/0.443
4jx1CAMCamphor 5-monooxygenase1.14.15.10.443
4k9yK9YFocal adhesion kinase 12.7.10.20.443
4kak06UDihydrofolate reductase1.5.1.30.443
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
2om9AJAPeroxisome proliferator-activated receptor gamma/0.442
2pvhP19Casein kinase II subunit alpha2.7.11.10.442
2pvmP29Casein kinase II subunit alpha2.7.11.10.442
2znq401Peroxisome proliferator-activated receptor delta/0.442
3a62STURibosomal protein S6 kinase beta-12.7.11.10.442
3mtlFEFCyclin-dependent kinase 162.7.11.220.442
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.442
4eevL1XHepatocyte growth factor receptor2.7.10.10.442
4ez50RSCyclin-dependent kinase 62.7.11.220.442
4kb81QOCasein kinase I isoform delta2.7.11.10.442
4otiMI1Serine/threonine-protein kinase N1/0.442
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.441
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
2c475IDCasein kinase I isoform gamma-2/0.441
2c6tDT5Cyclin-dependent kinase 22.7.11.220.441
2cchATPCyclin-dependent kinase 22.7.11.220.441
2eufLQQCyclin-dependent kinase 62.7.11.220.441
3a7hATPSerine/threonine-protein kinase 242.7.11.10.441
3nynSGVG protein-coupled receptor kinase 62.7.11.160.441
3vewADPnebramycin 5' synthase6.1.2.20.441
3vspEK8Peroxisome proliferator-activated receptor gamma/0.441
3vt8YI3Vitamin D3 receptor/0.441
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.441
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4eon1ROCyclin-dependent kinase 22.7.11.220.441
4gub0Y4Casein kinase II subunit alpha2.7.11.10.441
4nb6444Nuclear receptor ROR-gamma/0.441
4twpAXITyrosine-protein kinase ABL12.7.10.20.441
1e7qNAPGDP-L-fucose synthase/0.440
1ppm0P1Penicillopepsin-13.4.23.200.440
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.440
2uxuNARHTH-type transcriptional regulator TtgR/0.440
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.440
3g72A6TRenin3.4.23.150.440
3gu83GUDeath-associated protein kinase 12.7.11.10.440
3pm0BHFCytochrome P450 1B1/0.440
4b8mVX6Aurora kinase B-A2.7.11.10.440
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4eok4SPCyclin-dependent kinase 22.7.11.220.440
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.440
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4hvi19STyrosine-protein kinase JAK32.7.10.20.440
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440