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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.95

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.951.000
2pa3NAID-3-phosphoglycerate dehydrogenase1.1.1.950.598
2p9eNAID-3-phosphoglycerate dehydrogenase1.1.1.950.573
3ggoNAIPrephenate dehydrogenase/0.496
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.483
3gggNADPrephenate dehydrogenase/0.474
3ggpNADPrephenate dehydrogenase/0.457
2aa3AP0L-lactate dehydrogenase/0.451
4gl4NAIAlcohol dehydrogenase class-3/0.445
4lcjNADC-terminal-binding protein 2/0.441
3d64NADAdenosylhomocysteinase/0.440
4gh5NADShort-chain dehydrogenase/reductase SDR/0.440