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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.91.000
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.693
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.654
3eeiMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.614
3dp9BIG5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.613
4wkbTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.606
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.598
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.594
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.531
4s1iPLPPyridoxal kinase, putative/0.519
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.513
4dhyS41Glucokinase2.7.1.20.509
3zkyWT4Isopenicillin N synthase1.21.3.10.508
3ds6A17Mitogen-activated protein kinase 14/0.507
3s41S41Glucokinase2.7.1.20.507
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.507
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.505
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.505
1blzACVIsopenicillin N synthase1.21.3.10.504
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.504
4iwv1J9Glucokinase2.7.1.20.503
2ycyP32Beta-1 adrenergic receptor/0.502
1o6qR17Squalene--hopene cyclase4.2.1.1290.500
1h36R88Squalene--hopene cyclase4.2.1.1290.499
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.499
4ixc1JDGlucokinase2.7.1.20.499
4b4vL34Bifunctional protein FolD/0.498
2bu9HFVIsopenicillin N synthase1.21.3.10.497
4y0kNAPAntE/0.497
1hb1OCVIsopenicillin N synthase1.21.3.10.496
1ry0PG2Aldo-keto reductase family 1 member C3/0.496
1hb3SCVIsopenicillin N synthase1.21.3.10.495
1r8qAFBCytohesin-2/0.495
1r8qAFBADP-ribosylation factor 1/0.495
2iviACWIsopenicillin N synthase1.21.3.10.495
2yatEEUEstrogen receptor/0.495
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.495
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.494
1wxyFRKAdenosine deaminase3.5.4.40.494
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.493
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.493
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.492
3emlZMAAdenosine receptor A2a/0.492
2dhfDZFDihydrofolate reductase1.5.1.30.490
4bmzMTAAminodeoxyfutalosine nucleosidase/0.489
5uviZMAAdenosine receptor A2a/0.489
5k2aZMAAdenosine receptor A2a/0.489
1jlaTNKGag-Pol polyprotein2.7.7.490.488
1yhjR6CPyridoxal kinase2.7.1.350.488
2gvcFADThiol-specific monooxygenase1.14.130.488
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.488
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.488
2yczI32Beta-1 adrenergic receptor/0.488
1pqc444Oxysterols receptor LXR-beta/0.487
2y60M8FIsopenicillin N synthase1.21.3.10.487
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.487
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.487
5g53NECAdenosine receptor A2a/0.487
1uzwCDHIsopenicillin N synthase1.21.3.10.486
1ygjRMCPyridoxal kinase2.7.1.350.486
1zq5E04Aldo-keto reductase family 1 member C3/0.486
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.486
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.486
5iua6DXAdenosine receptor A2a/0.486
1pd9CO4Dihydrofolate reductase1.5.1.30.485
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.485
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.485
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.485
2gfsPQBMitogen-activated protein kinase 14/0.484
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.484
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.484
5k2cZMAAdenosine receptor A2a/0.484
1qjfACSIsopenicillin N synthase1.21.3.10.483
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.483
4dbs0HVAldo-keto reductase family 1 member C3/0.483
5a4vQUEGlutathione S-transferase F22.5.1.180.483
1bk0ACVIsopenicillin N synthase1.21.3.10.482
2jb4A14Isopenicillin N synthase1.21.3.10.482
2mjpANPdITP/XTP pyrophosphatase3.6.1.190.482
2p1t3TNRetinoic acid receptor RXR-alpha/0.482
2y6fM9FIsopenicillin N synthase1.21.3.10.482
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.482
3pfhT3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.482
4phlPILPhosphodiesterase/0.482
4twnB96Ephrin type-A receptor 32.7.10.10.482
1e2nRCAThymidine kinase/0.481
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.481
1mvtDTMDihydrofolate reductase1.5.1.30.481
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
1u1cBAUUridine phosphorylase2.4.2.30.481
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.481
2zb1GK4Mitogen-activated protein kinase 14/0.481
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.481
4b4w9L9Bifunctional protein FolD/0.481
4pztSOPHistone acetyltransferase p300/0.481
1mvsDTMDihydrofolate reductase1.5.1.30.480
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.480
3vf60H6Glucokinase2.7.1.20.480
4l0t1V0Tankyrase-22.4.2.300.480
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.480
7catNDPCatalase1.11.1.60.480
3ny8JRZBeta-2 adrenergic receptor/0.480
1obnASVIsopenicillin N synthase1.21.3.10.479
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.479
2r0pK2CPutative FAD-monooxygenase/0.479
2vcmM11Isopenicillin N synthase1.21.3.10.479
3ghvGHCDihydrofolate reductase1.5.1.30.479
4bhw01KHistone acetyltransferase p300/0.479
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.479
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.478
1w06W05Isopenicillin N synthase1.21.3.10.478
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.478
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.478
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.478
3hkwIX6Genome polyprotein2.7.7.480.477
5dp2NAPCurF/0.477
8catNDPCatalase1.11.1.60.477
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.476
3zkuHCVIsopenicillin N synthase1.21.3.10.476
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.476
4buwF33Tankyrase-22.4.2.300.476
3d4sTIMBeta-2 adrenergic receptor/0.476
1bzfTMQDihydrofolate reductase1.5.1.30.475
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.475
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.475
2ydoADNAdenosine receptor A2a/0.475
3csoXNIGenome polyprotein2.7.7.480.475
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.475
3r6iJMSAldo-keto reductase family 1 member C3/0.475
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.474
1synF89Thymidylate synthase/0.474
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.474
2x7hPFNProstaglandin reductase 310.474
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.474
3ix8TX3Transcriptional activator protein LasR/0.474
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.474
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
4bftZVTPantothenate kinase2.7.1.330.474
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.474
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
4g95OAGDihydrofolate reductase1.5.1.30.474
4kfj1R0Dihydrofolate reductase1.5.1.30.474
5kf8ACOPredicted acetyltransferase/0.474
5k2bZMAAdenosine receptor A2a/0.474
1h35R01Squalene--hopene cyclase4.2.1.1290.473
1kmvLIIDihydrofolate reductase1.5.1.30.473
1pz1NAPGeneral stress protein 69/0.473
2wksCB63-dehydroquinate dehydratase4.2.1.100.473
4bfsZVSPantothenate kinase2.7.1.330.473
4q0kGA3Phytohormone-binding protein/0.473
1s3uTQDDihydrofolate reductase1.5.1.30.472
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.472
3zoiM2WIsopenicillin N synthase1.21.3.10.472
4fhd0TTSpore photoproduct lyase/0.472
5kf2ACOPredicted acetyltransferase/0.472
5a8eXTKBeta-1 adrenergic receptor/0.472
1jwtBLIProthrombin3.4.21.50.471
1u1d181Uridine phosphorylase2.4.2.30.471
1zp4C2F5,10-methylenetetrahydrofolate reductase1.5.1.200.471
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.471
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.471
3eigMTXDihydrofolate reductase1.5.1.30.471
3exnACOProbable acetyltransferase/0.471
3ha3SAHHydroxymycolate synthase MmaA42.1.10.471
3ha7B32Hydroxymycolate synthase MmaA42.1.10.471
3oafOAGDihydrofolate reductase1.5.1.30.471
3tdaPN0Cytochrome P450 2D6/0.471
3up0D7SaceDAF-12/0.471
4kxjP34Nucleoprotein/0.471
3qakUKAAdenosine receptor A2a/0.471
1b48HAGGlutathione S-transferase A42.5.1.180.470
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.470
1oc1ASVIsopenicillin N synthase1.21.3.10.470
1xi2CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.470
1ygkRRCPyridoxal kinase2.7.1.350.470
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.469
2g1a5HGClass B acid phosphatase3.1.3.20.469
2re8GSUGlutamine--tRNA ligase6.1.1.180.469
3f3y4OABile salt sulfotransferase2.8.2.140.469
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.469
4dvi2IWTankyrase-12.4.2.300.469
1qipGNBLactoylglutathione lyase4.4.1.50.468
1txtCAAHMG-CoA synthase/0.468
1u72MTXDihydrofolate reductase1.5.1.30.468
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.468
2vbdV10Isopenicillin N synthase1.21.3.10.468
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.468
2z3uCRRCytochrome P450/0.468
3b9oFMNAlkane monoxygenase/0.468
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3nxyD2HDihydrofolate reductase1.5.1.30.468
3tfyCOAN-alpha-acetyltransferase 502.3.10.468
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.468
4bfuZVUPantothenate kinase2.7.1.330.468
4fam0SZAldo-keto reductase family 1 member C3/0.468
1crbRTLRetinol-binding protein 1/0.467
1d3dBZTProthrombin3.4.21.50.467
1k9sFM2Purine nucleoside phosphorylase DeoD-type/0.467
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.467
2vbpVB1Isopenicillin N synthase1.21.3.10.467
2wsiFADFAD synthase2.7.7.20.467
3fnfJPMEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
3nxrD2DDihydrofolate reductase1.5.1.30.467
4at0FADPossible succinate dehydrogenase/0.467
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.467
4dk70KSOxysterols receptor LXR-beta/0.467
1qtqQSIGlutamine--tRNA ligase6.1.1.180.466
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
2ol4JPNEnoyl-ACP reductase/0.466
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.466
3is9AC7Gag-Pol polyprotein2.7.7.490.466
3pg3DG7Mitogen-activated protein kinase 14/0.466
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.466
3qm4PN0Cytochrome P450 2D6/0.466
3rsv3RSBeta-secretase 13.4.23.460.466
4dsbA8SAbscisic acid receptor PYL3/0.466
4eh8IRGMitogen-activated protein kinase 14/0.466
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.466
4kak06UDihydrofolate reductase1.5.1.30.466
4s0vSUVOrexin receptor type 2/0.466
1dghNDPCatalase1.11.1.60.465
1g6oADPCag alpha/0.465
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.465
1re0AFBADP-ribosylation factor 1/0.465
1re0AFBARF guanine-nucleotide exchange factor 1/0.465
2wo7ASVIsopenicillin N synthase1.21.3.10.465
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.465
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.465
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.465
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.465
1c4yIH3Prothrombin3.4.21.50.464
1e92HBIPteridine reductase 11.5.1.330.464
1ej3CZHAequorin-2/0.464
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.464
1ohjCOPDihydrofolate reductase1.5.1.30.464
1pq944BOxysterols receptor LXR-beta/0.464
2vcwZZAHematopoietic prostaglandin D synthase/0.464
2yk2YJXHeat shock protein HSP 90-alpha/0.464
3gkiCLRNiemann-Pick C1 protein/0.464
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.464
3vt9YI4Vitamin D3 receptor/0.464
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.464
1iepSTITyrosine-protein kinase ABL12.7.10.20.463
1rtiHEFGag-Pol polyprotein2.7.7.490.463
2bf7HBIPteridine reductase 11.5.1.330.463
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.463
3d7zGK5Mitogen-activated protein kinase 14/0.463
3if9FADGlycine oxidase1.4.3.190.463
3n87N873-dehydroquinate dehydratase4.2.1.100.463
3p6oETGCamphor 5-monooxygenase1.14.15.10.463
4bfxZVXPantothenate kinase2.7.1.330.463
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.463
4kd79DRDihydrofolate reductase1.5.1.30.463
4kfjFOLDihydrofolate reductase1.5.1.30.463
4m8hR4MRetinoic acid receptor RXR-alpha/0.463
4x28FDAAcyl-CoA dehydrogenase FadE26/0.463
4x28FDAAcyl-CoA dehydrogenase FadE27/0.463
5a2yUTPMitochondrial poly(A) polymerase/0.463
1axwMTXThymidylate synthase/0.462
1drfFOLDihydrofolate reductase1.5.1.30.462
1o6rR19Squalene--hopene cyclase4.2.1.1290.462
1qsnCOAHAT A1/0.462
1sweBTNStreptavidin/0.462
1y56FMNUncharacterized protein/0.462
1y56FMN382aa long hypothetical sarcosine oxidase/0.462
2jj2ADPATP synthase subunit alpha, mitochondrial/0.462
2jj2ADPATP synthase subunit beta, mitochondrial3.6.3.140.462
2qimZEAClass 10 plant pathogenesis-related protein/0.462
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.462
3nu03TUDihydrofolate reductase1.5.1.30.462
3pqbVGPPutative oxidoreductase/0.462
4bb3KKAIsopenicillin N synthase1.21.3.10.462
4bueJQFTankyrase-22.4.2.300.462
4rv9SAHD-mycarose 3-C-methyltransferase/0.462
4u9vACON-alpha-acetyltransferase 402.3.10.462
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.461
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.461
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.461
1opbRETRetinol-binding protein 2/0.461
1ry8RUTAldo-keto reductase family 1 member C3/0.461
1trgCB3Thymidylate synthase/0.461
1uhjCZBAequorin-2/0.461
2bfpH4BPteridine reductase 11.5.1.330.461
2ibwCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.461
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.461
2xviFADPutative flavin-containing monooxygenase/0.461
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.461
3c35KAIGlutamate receptor ionotropic, kainate 1/0.461
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3g70A5TRenin3.4.23.150.461
3lfeZ84Mitogen-activated protein kinase 14/0.461
3nxoD2BDihydrofolate reductase1.5.1.30.461
3qri919Tyrosine-protein kinase ABL12.7.10.20.461
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3ug8IMNAldo-keto reductase family 1 member C3/0.461
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.461
4psbGA3Cytokinin-specific binding protein/0.461
5jtbZMAAdenosine receptor A2a/0.461
1exa394Retinoic acid receptor gamma/0.460
1jtqLY3Thymidylate synthase/0.460
1kf6HQOFumarate reductase iron-sulfur subunit1.3.5.10.460
1kf6HQOFumarate reductase subunit C/0.460
1kf6HQOFumarate reductase subunit D/0.460
1odnAPVIsopenicillin N synthase1.21.3.10.460
1t48BB3Tyrosine-protein phosphatase non-receptor type 13.1.3.480.460
1typNAPTrypanothione reductase1.8.1.120.460
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.460
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.460
2zscBTNTamavidin2/0.460
3br9DEYGenome polyprotein2.7.7.480.460
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3htjETEbrA repressor/0.460
3q44D50M1 family aminopeptidase3.4.110.460
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
4a87NARMajor pollen allergen Bet v 1-A/0.460
4epq0RRPoly(ADP-ribose) glycohydrolase/0.460
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.460
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.460
4h7c10HAldo-keto reductase family 1 member C3/0.460
4o2z046Mitogen-activated protein kinase/0.460
5kf1ACOPredicted acetyltransferase/0.460
1cbrREACellular retinoic acid-binding protein 1/0.459
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.459
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.459
1ndyFR3Adenosine deaminase3.5.4.40.459
1sqbAZOCytochrome b/0.459
2xveFADPutative flavin-containing monooxygenase/0.459
3cr0809Wee1-like protein kinase2.7.10.20.459
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3gncQQQGlutaryl-CoA dehydrogenase/0.459
3hfbML4Tryptophan 5-hydroxylase 11.14.16.40.459
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.459
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
4o701QKBromodomain-containing protein 4/0.459
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.459
5iu4ZMAAdenosine receptor A2a/0.459
1dhfFOLDihydrofolate reductase1.5.1.30.458
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
1nhkCMPNucleoside diphosphate kinase2.7.4.60.458
1qiqACCIsopenicillin N synthase1.21.3.10.458
1rzy5ASHistidine triad nucleotide-binding protein 130.458
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
2geuCOKPantothenate kinase2.7.1.330.458
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2zda32UProthrombin3.4.21.50.458
2zevB71Geranylgeranyl pyrophosphate synthase/0.458
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.458
3f0aACOSpermidine N(1)-acetyltransferase/0.458
3gnvXNZGenome polyprotein2.7.7.480.458
3mcyZH1FimH/0.458
3wv9FEGHmd co-occurring protein HcgE/0.458
4ea2RWZDehydrosqualene synthase/0.458
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.458
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
1swdBTNStreptavidin/0.457
1umlFR4Adenosine deaminase3.5.4.40.457
1zgv501Prothrombin3.4.21.50.457
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
2pswCOAN-alpha-acetyltransferase 50/0.457
2vczVC3Hematopoietic prostaglandin D synthase/0.457
3dlgGWEGag-Pol polyprotein2.7.7.490.457
3n0hTOPDihydrofolate reductase1.5.1.30.457
3oiaA31Camphor 5-monooxygenase1.14.15.10.457
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.457
4bud29FTankyrase-22.4.2.300.457
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.457
4hfp15UProthrombin3.4.21.50.457
4nieNBHNuclear receptor ROR-gamma/0.457
4xbjIN5Alanine racemase, biosynthetic/0.457
5cc9DDFDihydrofolate reductase1.5.1.30.457
1hfqMOTDihydrofolate reductase1.5.1.30.456
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.456
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.456
2bfaCB3Pteridine reductase 11.5.1.330.456
2bjsACVIsopenicillin N synthase1.21.3.10.456
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.456
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.456
3bj7COADiamine acetyltransferase 1/0.456
3dtwA96Vascular endothelial growth factor receptor 22.7.10.10.456
3fktSIIBeta-secretase 13.4.23.460.456
3ghwGHWDihydrofolate reductase1.5.1.30.456
3ol5SAWCamphor 5-monooxygenase1.14.15.10.456
3qe2FMNNADPH--cytochrome P450 reductase/0.456
3qpg3QPAspartate aminotransferase2.6.1.10.456
3rix923Luciferin 4-monooxygenase1.13.12.70.456
3sf6FDAGlutaryl-CoA dehydrogenase/0.456
4a86H35Major pollen allergen Bet v 1-A/0.456
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.456
4bfyZVYPantothenate kinase2.7.1.330.456
4d9eLCSD-cysteine desulfhydrase/0.456
4j6cSTRCytochrome P450 monooxygenase/0.456
4pnmNU1Tankyrase-22.4.2.300.456
4rheFMNFlavin prenyltransferase UbiX/0.456
4xwtU5PRibonuclease J/0.456
4y1bNAPAntE/0.456
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.455
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.455
1g63FMNEpidermin decarboxylase4.1.10.455
1jtuLYBThymidylate synthase/0.455
1mbzIOTCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.455
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.455
1uhhCZPAequorin-2/0.455
1w7h3IPMitogen-activated protein kinase 14/0.455
1xf0ASDAldo-keto reductase family 1 member C3/0.455
2cbqTH2Neocarzinostatin/0.455
2culFADGidA-related protein/0.455
2jdcCAOProbable acetyltransferase/0.455
2og81N8Tyrosine-protein kinase Lck2.7.10.20.455
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.455
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.455
3a1l2CCCytochrome P450/0.455
3dmjGWEPol protein/0.455
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.455
3ou2SAHSAM-dependent methyltransferase/0.455
3rgaILDEpoxide hydrolase LasB5.5.10.455
4kbn25UDihydrofolate reductase1.5.1.30.455
4pl9ADPEthylene receptor 1/0.455
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.454
1lnmDTXBilin-binding protein/0.454
1mrqSTRAldo-keto reductase family 1 member C1/0.454
1odcA8BAcetylcholinesterase3.1.1.70.454
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.454
1yf3SAHDNA adenine methylase/0.454
2fzjDH3Dihydrofolate reductase1.5.1.30.454
2vezACOGlucosamine 6-phosphate acetyltransferase, putative/0.454
2vt4P32Beta-1 adrenergic receptor/0.454
2zc922UProthrombin3.4.21.50.454
3c3xNAPEugenol synthase 11.1.1.3180.454
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.454
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.454
3tp0FO5HTH-type transcriptional regulator EthR/0.454
3vt7VDXVitamin D3 receptor/0.454
5dozNDPJamJ/0.454
4mqt2CUMuscarinic acetylcholine receptor M2/0.454
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.453
1n9mBTNStreptavidin/0.453
1ndzFR5Adenosine deaminase3.5.4.40.453
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.453
2bfmTOPPteridine reductase 11.5.1.330.453
2ejzSAHDiphthine synthase/0.453
2hveADPNucleoside diphosphate kinase A2.7.4.60.453
2z78H86Geranylgeranyl pyrophosphate synthase/0.453
3abiNADUncharacterized protein/0.453
3p2oNADBifunctional protein FolD/0.453
3q43D66M1 family aminopeptidase3.4.110.453
3up3XCAaceDAF-12/0.453
4aa0AA0Mitogen-activated protein kinase 14/0.453
4bj9UHBTankyrase-22.4.2.300.453
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.453
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.453
4ia1BIVVitamin D3 receptor A/0.453
4n4v2GYTankyrase-12.4.2.300.453
4x9dU5PUncharacterized protein MJ1435/0.453
4yklGMPAprataxin-like protein30.453
3nyaJTZBeta-2 adrenergic receptor/0.453
1k9sFM1Purine nucleoside phosphorylase DeoD-type/0.452
1kceCB3Thymidylate synthase/0.452
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.452
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.452
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.452
2mm3CHOGastrotropin/0.452
2xtbKRMAdenosine kinase, putative/0.452
2xvhFADPutative flavin-containing monooxygenase/0.452
2zsdCOAPantothenate kinase2.7.1.330.452
3dgeADPSensor histidine kinase/0.452
3e92G6AMitogen-activated protein kinase 14/0.452
3gyf51PDihydrofolate reductase1.5.1.30.452
3hkyIX6Genome polyprotein2.7.7.480.452
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.452
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.452
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.452
4bfpSWYTankyrase-22.4.2.300.452
4c2wANPAurora kinase B-A2.7.11.10.452
4eiyZMAAdenosine receptor A2a/0.452
4i8vBHFCytochrome P450 1A11.14.14.10.452
4l091URTankyrase-22.4.2.300.452
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4n1gCEIObelin/0.452
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.452
1bx9GLY_GGL_FOEGlutathione S-transferase F22.5.1.180.451
1diuBDMDihydrofolate reductase1.5.1.30.451
1mepBTNStreptavidin/0.451
1pq6965Oxysterols receptor LXR-beta/0.451
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
1swtBTNStreptavidin/0.451
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.451
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.451
2fhlBNIAvidin-related protein 4/5/0.451
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.451
2nq8ZIDEnoyl-ACP reductase/0.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3ix4TX1Transcriptional activator protein LasR/0.451
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.451
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.451
3tg4SAMN-lysine methyltransferase SMYD2/0.451
4bfwZVWPantothenate kinase2.7.1.330.451
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4glx0XSDNA ligase6.5.1.20.451
4iae1DXAlr2278 protein/0.451
4j6dTESCytochrome P450 monooxygenase/0.451
4jq3ZOMAldo-keto reductase family 1 member C2/0.451
4m6kFOLDihydrofolate reductase1.5.1.30.451
4y9lFADAcyl-CoA dehydrogenase family member 11/0.451
5kf9ACOPredicted acetyltransferase/0.451
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1xlsREARetinoic acid receptor RXR-alpha/0.450
1ychFMNNitric oxide reductase10.450
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.450
2dxiATPGlutamate--tRNA ligase6.1.1.170.450
2fwyH64Heat shock protein HSP 90-alpha/0.450
2jj1ADPATP synthase subunit alpha, mitochondrial/0.450
2jj1ADPATP synthase subunit beta, mitochondrial3.6.3.140.450
2lbdREARetinoic acid receptor gamma/0.450
2qg2A91Heat shock protein HSP 90-alpha/0.450
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.450
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.450
3e4aQIXInsulin-degrading enzyme3.4.24.560.450
3eufBAUUridine phosphorylase 1/0.450
3ewsADPATP-dependent RNA helicase DDX19B3.6.4.130.450
3nxvD2FDihydrofolate reductase1.5.1.30.450
3p3zP3ZPutative cytochrome P450/0.450
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3vi5M4MHematopoietic prostaglandin D synthase/0.450
4ap0ADPKinesin-like protein KIF11/0.450
4dbw511Aldo-keto reductase family 1 member C3/0.450
4ez8DHFThymidylate synthase2.1.1.450.450
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4fqsLYAThymidylate synthase ThyA/0.450
4hkkAGITankyrase-22.4.2.300.450
4qii2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.450
4yfy0FXVioF/0.450
5ab7MLCNonspecific lipid-transfer protein, putative/0.450
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.450
5emhNAPIridoid synthase1.3.1.990.450
1eioGCHGastrotropin/0.449
1f4gTP4Thymidylate synthase/0.449
1pj6FOLDimethylglycine oxidase1.5.3.100.449
1tgv5UDUridine phosphorylase2.4.2.30.449
1ut6A8NAcetylcholinesterase3.1.1.70.449
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2e0nSAHPrecorrin-2 C20-methyltransferase/0.449
2e48FADD-amino-acid oxidase1.4.3.30.449
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2pdaTPPPyruvate synthase/0.449
2rd2QSIGlutamine--tRNA ligase6.1.1.180.449
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.449
2ydvNECAdenosine receptor A2a/0.449
3f63GTXGlutathione transferase GST1-4/0.449
3h2lYAKGenome polyprotein2.7.7.480.449
3hqdANPKinesin-like protein KIF11/0.449
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3l3rOAGDihydrofolate reductase1.5.1.30.449
3l71AZOCytochrome b/0.449
3l77NJPShort-chain alcohol dehydrogenase/0.449
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4ddrMMVDihydrofolate reductase1.5.1.30.449
4dyp0MSNucleoprotein/0.449
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.449
4zthGG5Mitogen-activated protein kinase 14/0.449
5fd8A5APutative carboxypeptidase yocD/0.449
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.448
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.448
1h60STRPentaerythritol tetranitrate reductase/0.448
1lhuESTSex hormone-binding globulin/0.448
1ohkCOPDihydrofolate reductase1.5.1.30.448
1qu3MRCIsoleucine--tRNA ligase6.1.1.50.448
1upw444Oxysterols receptor LXR-beta/0.448
1uy7PU4Heat shock protein HSP 90-alpha/0.448
1zdwFLVPrenyltransferase/0.448
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
2b58COADiamine acetyltransferase 1/0.448
2bdyUNBProthrombin3.4.21.50.448
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.448
2giqNN2Genome polyprotein2.7.7.480.448
2jibADPOxalyl-CoA decarboxylase4.1.1.80.448
2pdlTOLAldose reductase1.1.1.210.448
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.448
3h59H59Genome polyprotein2.7.7.480.448
3hl0NADMaleylacetate reductase/0.448
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3iktNADRedox-sensing transcriptional repressor Rex/0.448
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.448
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.448
3oadLPORenin3.4.23.150.448
3ox4NADAlcohol dehydrogenase 21.1.1.10.448
3p0pNNFTankyrase-22.4.2.300.448
3p6pA6BCamphor 5-monooxygenase1.14.15.10.448
3px2T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.448
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.448
4ax9N5NProthrombin3.4.21.50.448
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4bs4A64Tankyrase-22.4.2.300.448
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4jlj1NMDeoxycytidine kinase2.7.1.740.448
4lb2DM5Serum albumin/0.448
5bt42LOBromodomain-containing protein 4/0.448
5cmx0G6Prothrombin3.4.21.50.448
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.447
1disBDMDihydrofolate reductase1.5.1.30.447
1f4eTPRThymidylate synthase/0.447
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.447
1lkeDOGBilin-binding protein/0.447
1oz0MS1Bifunctional purine biosynthesis protein PURH2.1.2.30.447
1rzuADPGlycogen synthase 12.4.1.210.447
1s3wTQTDihydrofolate reductase1.5.1.30.447
1zgbA1EAcetylcholinesterase3.1.1.70.447
2c9bPUG6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2ph5NADHomospermidine synthase/0.447
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.447
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3tyvHI3Genome polyprotein2.7.7.480.447
3vt8YI3Vitamin D3 receptor/0.447
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.447
4g1nNZTPyruvate kinase PKM2.7.1.400.447
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.447
4iaq2GM5-hydroxytryptamine receptor 1B/0.447
4jlk1NODeoxycytidine kinase2.7.1.740.447
4jln18VDeoxycytidine kinase2.7.1.740.447
4kebFOLDihydrofolate reductase1.5.1.30.447
4ku5DCC3-oxoacyl-[ACP] synthase III/0.447
4kzl20DTankyrase-22.4.2.300.447
4omaLCSMethionine gamma-lyase/0.447
1booSAHModification methylase PvuII2.1.1.1130.446
1c7oPPGHemolysin/0.446
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.446
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.446
1n71COAAac(6')-Ii protein/0.446
1nc9IMIStreptavidin/0.446
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.446
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
2msdGNPMHC class I alpha chain/0.446
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.446
2r2gEMFEugenol synthase 11.1.1.3180.446
2r8pT6FTransketolase 1/0.446
2wpxACOOrf14/0.446
2xvfFADPutative flavin-containing monooxygenase/0.446
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.446
3gsiTHGDimethylglycine oxidase1.5.3.100.446
3p9tTCLRepressor/0.446
3r43ID8Aldo-keto reductase family 1 member C3/0.446
3zj0ACOPutative acetyltransferase OgpAT/0.446
4e2yJHZMethyltransferase/0.446
4eqsCOACoenzyme A disulfide reductase/0.446
4jbtASDCytochrome P450 monooxygenase/0.446
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.446
4qa0SHHHistone deacetylase 83.5.1.980.446
4rbs0RVMetallo-beta-lactamase type 2/0.446
4relKMPGlycosyltransferase/0.446
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.446
4utlFNRXenobiotic reductase/0.446
4yvbBTNStreptavidin/0.446
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.446
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.446
4ug2NGIAdenosine receptor A2a/0.446
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.445
1dlsMTXDihydrofolate reductase1.5.1.30.445
1e79ADPATP synthase subunit alpha, mitochondrial/0.445
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.445
1hfrMOTDihydrofolate reductase1.5.1.30.445
1ja1FMNNADPH--cytochrome P450 reductase/0.445
1osvCHCBile acid receptor/0.445
1s9dAFBCytohesin-2/0.445
1s9dAFBADP-ribosylation factor 1/0.445
2b82ADNClass B acid phosphatase3.1.3.20.445
2c3p1TPPyruvate synthase/0.445
2nr4FMNConserved protein/0.445
2xlpFADPutative flavin-containing monooxygenase/0.445
3gx9TXDMorphinone reductase/0.445
3nxtD2EDihydrofolate reductase1.5.1.30.445
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
3ua108YCytochrome P450 3A4/0.445
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.445
3v94WYQPhosphodiesterase/0.445
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4ih61EPGenome polyprotein2.7.7.480.445
4ixd1HVIntegrin alpha-L/0.445
4l2g1V4Tankyrase-22.4.2.300.445
4li61XOTankyrase-12.4.2.300.445
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.445
2rh1CAUBeta-2 adrenergic receptor/0.445
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.444
1nw4IMHPurine nucleoside phosphorylase/0.444
1p8dCO1Oxysterols receptor LXR-beta/0.444
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.444
1s2cFLFAldo-keto reductase family 1 member C3/0.444
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
1uydPU8Heat shock protein HSP 90-alpha/0.444
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2bxnIDBSerum albumin/0.444
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2hdjNDPAldo-keto reductase family 1 member C2/0.444
2hvdADPNucleoside diphosphate kinase A2.7.4.60.444
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.444
2o7pNAPRiboflavin biosynthesis protein RibD/0.444
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.444
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.444
2wpwACOOrf14/0.444
2zb8IMNProstaglandin reductase 21.3.1.480.444
3ft8MOJHeat shock protein HSP 90-alpha/0.444
3mp5HMGHydroxymethylglutaryl-CoA lyase, mitochondrial4.1.3.40.444
3qwc98PProthrombin3.4.21.50.444
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.444
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.444
4b6uM7GEukaryotic translation initiation factor 4E type 3/0.444
4b78KGGBeta-secretase 13.4.23.460.444
4bqg50QHeat shock protein HSP 90-alpha/0.444
4bufF36Tankyrase-22.4.2.300.444
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.444
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4i9i1DYTankyrase-12.4.2.300.444
4l0v1V1Tankyrase-22.4.2.300.444
5h841VUHistone acetyltransferase KAT2A2.3.1.480.444
5iubCLRAdenosine receptor A2a/0.444
5kgjACOPredicted acetyltransferase/0.444
4gbrCAUBeta-2 adrenergic receptor/0.444
3sn6P0GBeta-2 adrenergic receptor/0.444
3uzcT4EAdenosine receptor A2a/0.444
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.443
1lwlDSOCamphor 5-monooxygenase1.14.15.10.443
1ogjFADFerredoxin--NADP reductase1.18.1.20.443
1ycfFMNNitric oxide reductase10.443
2flhZEACytokinin-specific binding protein/0.443
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2ivfMGDAlpha-subunit of ethylbenzene dehydrogenase/0.443
2zi224UProthrombin3.4.21.50.443
3acy702Dehydrosqualene synthase/0.443
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3iej599Cathepsin S3.4.22.270.443
3lkhLT6Genome polyprotein2.7.7.480.443
3llaACPMyosin heavy chain kinase A2.7.11.70.443
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.443
3owaFADAcyl-CoA dehydrogenase/0.443
3r8gIZPAldo-keto reductase family 1 member C3/0.443
3u4o08EGenome polyprotein2.7.7.480.443
3uph0C1Genome polyprotein2.7.7.480.443
3w6hAZMCarbonic anhydrase 14.2.1.10.443
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.443
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
4gvsF4MMethenyltetrahydromethanopterin cyclohydrolase3.5.4.270.443
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.443
4l1xNAPAldo-keto reductase family 1 member C2/0.443
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4wasCOOEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.443
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.443
5ej4TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
5irnADPNucleotide binding oligomerization domain containing 2/0.443
1jf0CZHObelin/0.442
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.442
1lb9DNQGlutamate receptor 2/0.442
1reqDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.442
1s36CEIObelin/0.442
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.442
1z71L17Prothrombin3.4.21.50.442
2aclL05Oxysterols receptor LXR-alpha/0.442
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.442
2bakAQZMitogen-activated protein kinase 14/0.442
2bt4CA23-dehydroquinate dehydratase4.2.1.100.442
2c42TPPPyruvate synthase/0.442
2cv2GSUGlutamate--tRNA ligase6.1.1.170.442
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.442
2hzqSTRApolipoprotein D/0.442
2idkC2FGlycine N-methyltransferase2.1.1.200.442
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.442
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.442
2r3xGTXGlutathione S-transferase A12.5.1.180.442
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.442
2ydwWSHBromodomain-containing protein 2/0.442
2ykiYKIHeat shock protein HSP 90-alpha/0.442
2zxgS23Aminopeptidase N3.4.11.20.442
2zymACXPeriplasmic binding protein/0.442
3bgiSAHThiopurine S-methyltransferase2.1.1.670.442
3e5aVX6Aurora kinase A2.7.11.10.442
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
3oxk5GPHistidine triad nucleotide-binding protein30.442
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.442
3q0uLL3HTH-type transcriptional regulator EthR/0.442
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.442
4a9yAQZMitogen-activated protein kinase 14/0.442
4buxF35Tankyrase-22.4.2.300.442
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.442
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4ieiADPGene 2 protein/0.442
4jdaA9SAbscisic acid receptor PYL3/0.442
4jlm1NNDeoxycytidine kinase2.7.1.740.442
4l7g1W0Beta-secretase 13.4.23.460.442
4mk928RGenome polyprotein2.7.7.480.442
4nbn2J7Caspase-63.4.22.590.442
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.442
4xulGTPUncharacterized protein mg662/0.442
5ab6CAANonspecific lipid-transfer protein, putative/0.442
1bu5RBFFlavodoxin/0.441
1d6w00RProthrombin3.4.21.50.441
1e7aPFLSerum albumin/0.441
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1jomFFODihydrofolate reductase1.5.1.30.441
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1n83CLRNuclear receptor ROR-alpha/0.441
1rxjBNIStreptavidin/0.441
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.441
1uy9PU6Heat shock protein HSP 90-alpha/0.441
1w6rGNTAcetylcholinesterase3.1.1.70.441
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1z5uCMPClass B acid phosphatase/0.441
2a4xBLMMitomycin-binding protein/0.441
2c3oTPPPyruvate synthase/0.441
2c4cFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.441
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.441
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
3d4bDZDNAD-dependent protein deacetylase/0.441
3hllI46Mitogen-activated protein kinase 14/0.441
3ou6SAMSAM-dependent methyltransferase/0.441
3q7fED2Uncharacterized protein/0.441
3w78CBDFMN-dependent NADH-azoreductase/0.441
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.441
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.441
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.441
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4iw8KN3Estrogen receptor/0.441
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.441
4lzwTHMUridine phosphorylase/0.441
4n3l2FNProthrombin3.4.21.50.441
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.441
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.441
5jqhCAUBeta-2 adrenergic receptor/0.441
1b87ACOAac(6')-Ii protein/0.440
1el4CTZObelin/0.440
1flsWAYCollagenase 33.4.240.440
1h42FADFerredoxin--NADP reductase1.18.1.20.440
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.440
1rszDIHPurine nucleoside phosphorylase2.4.2.10.440
1ycgFMNNitric oxide reductase10.440
2c3yHTLPyruvate synthase/0.440
2j9lATPH(+)/Cl(-) exchange transporter 5/0.440
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.440
2x23TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2xlrFADPutative flavin-containing monooxygenase/0.440
2xpuTDCTetracycline repressor protein class D/0.440
3arvSAUChitinase A/0.440
3fu9KIBLaccase-11.10.3.20.440
3fznD7KBenzoylformate decarboxylase4.1.1.70.440
3ndjJHZMethyltransferase/0.440
3q9bB3NAcetylpolyamine amidohydrolase/0.440
3rviRVIBeta-secretase 13.4.23.460.440
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.440
3thrC2FGlycine N-methyltransferase2.1.1.200.440
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4bus32FTankyrase-22.4.2.300.440
4e2zJHZMethyltransferase/0.440
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.440
4q15HFGProline--tRNA ligase6.1.1.150.440
4u2lSFDCholesterol oxidase1.1.3.60.440
5a4wQCTGlutathione S-transferase F22.5.1.180.440
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.440