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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.29

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.291.000
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.594
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.567
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.550
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.546
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.545
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.540
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.537
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.533
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.527
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.517
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.509
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.508
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.500
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.491
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.489
1q66KMBQueuine tRNA-ribosyltransferase2.4.2.290.477
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.473
1r5yDQUQueuine tRNA-ribosyltransferase2.4.2.290.472
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.466
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.458
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.455
3sn6P0GBeta-2 adrenergic receptor/0.454
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.449
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.445