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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1xvtCOAL-carnitine CoA-transferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1xvtCOAL-carnitine CoA-transferase/1.000
1xvvCCQL-carnitine CoA-transferase/0.567
1xa4COAL-carnitine CoA-transferase/0.534
3rsv3RSBeta-secretase 13.4.23.460.524
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.523
2i4qUA4Renin3.4.23.150.518
2g1y5IGRenin3.4.23.150.514
4jiq1L5GTN Reductase/0.507
1h60STRPentaerythritol tetranitrate reductase/0.504
2abaSTRPentaerythritol tetranitrate reductase/0.500
4bb3KKAIsopenicillin N synthase1.21.3.10.500
4v2gITCTetracycline repressor protein class D/0.500
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.500
2g1o2IGRenin3.4.23.150.499
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.498
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.495
3junAJDPhenazine biosynthesis protein A/B/0.494
4de2DN3Beta-lactamase/0.494
2ptfFMNUncharacterized protein MTH_863/0.492
2ejzSAHDiphthine synthase/0.491
2ikuLIYRenin3.4.23.150.491
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.491
2g1n1IGRenin3.4.23.150.490
3ekuCY9Actin-5C/0.490
3qeoLLTDeoxycytidine kinase2.7.1.740.490
3kigDA4Carbonic anhydrase 24.2.1.10.489
4ht2V50Carbonic anhydrase 124.2.1.10.489
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.489
1icpFMN12-oxophytodienoate reductase 11.3.1.420.488
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.488
2dvlFADAcyl-CoA dehydrogenase/0.487
2gv8NDPThiol-specific monooxygenase1.14.130.487
3qt62P0Mevalonate diphosphate decarboxylase/0.487
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.487
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.486
1nm6L86Prothrombin3.4.21.50.485
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.485
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.485
3c1kT15Prothrombin3.4.21.50.484
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.483
3af1GDPPantothenate kinase2.7.1.330.483
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.483
4lu3AZMCarbonic anhydrase 144.2.1.10.483
1h62ANBPentaerythritol tetranitrate reductase/0.482
1mu6CDAProthrombin3.4.21.50.482
2g1r3IGRenin3.4.23.150.482
2x06NADL-sulfolactate dehydrogenase/0.482
1dljUGAUDP-glucose 6-dehydrogenase/0.481
2vutNADNitrogen metabolite repression protein nmrA/0.481
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.480
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.480
3mjrAC2Deoxycytidine kinase2.7.1.740.480
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.479
2a2xNA9Prothrombin3.4.21.50.479
2g247IGRenin3.4.23.150.479
3coy53HPantothenate synthetase6.3.2.10.479
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.479
4m0f1YKAcetylcholinesterase3.1.1.70.479
4tmcFMNOld yellow enzyme/0.479
2cekN8TAcetylcholinesterase3.1.1.70.478
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.478
1aqv0HGGlutathione S-transferase P2.5.1.180.477
1bn1AL5Carbonic anhydrase 24.2.1.10.477
1dx6GNTAcetylcholinesterase3.1.1.70.477
3fr5I4AFatty acid-binding protein, adipocyte/0.477
3zeiAWHO-acetylserine sulfhydrylase/0.477
4j7gTRHPCZA361.3/0.477
4kbyC2EStimulator of interferon genes protein/0.477
4mk828QGenome polyprotein2.7.7.480.477
1bil0IURenin3.4.23.150.476
3oqfS51Renin3.4.23.150.476
3otwCOAPhosphopantetheine adenylyltransferase/0.476
4arbC57Acetylcholinesterase3.1.1.70.476
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.476
2gstGPSGlutathione S-transferase Mu 12.5.1.180.475
3mdzEZLCarbonic anhydrase 74.2.1.10.475
3vyfVYFRenin3.4.23.150.475
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.474
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.474
4xbjIN5Alanine racemase, biosynthetic/0.474
1jd0AZMCarbonic anhydrase 124.2.1.10.473
2g21L1BRenin3.4.23.150.473
4bfzZVZPantothenate kinase2.7.1.330.473
1ta6177Prothrombin3.4.21.50.472
3c27DKKProthrombin3.4.21.50.472
4ey6GNTAcetylcholinesterase3.1.1.70.472
4j7hTRHPCZA361.3/0.472
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.472
5fltVJJCarbonic anhydrase 24.2.1.10.472
2o12FMNChorismate synthase/0.471
2x3jATPAcsD/0.471
2xupTZ5Acetylcholinesterase3.1.1.70.471
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.471
4bfvZVVPantothenate kinase2.7.1.330.471
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.471
4lez1SYCyclic GMP-AMP synthase/0.471
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.470
2vkeTACTetracycline repressor protein class D/0.470
4loi1YCStimulator of interferon genes protein/0.470
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.470
1psa0ZLPepsin A3.4.23.10.469
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.469
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.469
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.469
4g090VDHistidinol dehydrogenase/0.469
4j1tNAPNAD(P) transhydrogenase subunit beta/0.469
4qxp1YEStimulator of interferon genes protein/0.469
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.469
2iko7IGRenin3.4.23.150.468
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3a0tADPSensor histidine kinase/0.468
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.468
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.468
7stdCRPScytalone dehydratase4.2.1.940.468
1dliUDXUDP-glucose 6-dehydrogenase/0.467
1z71L17Prothrombin3.4.21.50.467
2g226IGRenin3.4.23.150.467
3g72A6TRenin3.4.23.150.467
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.467
4araC56Acetylcholinesterase3.1.1.70.467
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.467
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.467
1bwsNDPGDP-L-fucose synthase/0.466
1c4vIH2Prothrombin3.4.21.50.466
2fj1CTCTetracycline repressor protein class D/0.466
2g0bNLTLong-chain N-acyl amino acid synthase/0.466
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.466
2po3T4K4-dehydrase/0.466
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.466
3hl0NADMaleylacetate reductase/0.466
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.466
4ddhMS0Pantothenate synthetase6.3.2.10.466
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.465
1vfsDCSAlanine racemase/0.465
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.465
2g8yNADHydroxycarboxylate dehydrogenase B/0.465
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.465
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.465
3lpkZ76Beta-secretase 13.4.23.460.465
3pgtGBXGlutathione S-transferase P2.5.1.180.465
2j3qTFLAcetylcholinesterase3.1.1.70.464
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.464
3ge6FMNNitroreductase/0.464
3h3qH13Collagen type IV alpha-3-binding protein/0.464
3n9jEAAGlutathione S-transferase P2.5.1.180.464
3vsxR32Renin3.4.23.150.464
3w5uFADFerredoxin/0.464
4bzbDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.464
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.464
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
4xiwAZMCarbonic anhydrase, alpha type/0.464
1fmjRTLRetinol dehydratase/0.463
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.463
2g1s4IGRenin3.4.23.150.463
2glrGTXGlutathione S-transferase P 12.5.1.180.463
2zcvNDPQuinone oxidoreductase 21.6.5.20.463
3oqkS52Renin3.4.23.150.463
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.463
4bfwZVWPantothenate kinase2.7.1.330.463
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.463
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.462
2c12FADNitroalkane oxidase1.7.3.10.462
3cb2GDPTubulin gamma-1 chain/0.462
3s5wFADL-ornithine N(5)-monooxygenase/0.462
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.462
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.461
1q45FMN12-oxophytodienoate reductase 31.3.1.420.461
2ha6SCKAcetylcholinesterase3.1.1.70.461
2jl1NAPTriphenylmethane reductase/0.461
2xuoTZ4Acetylcholinesterase3.1.1.70.461
3zkyWT4Isopenicillin N synthase1.21.3.10.461
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.461
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.461
4nv7COAArylamine N-acetyltransferase/0.461
1d3pBT3Prothrombin3.4.21.50.460
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.460
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.460
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.460
2x7hPFNProstaglandin reductase 310.460
3cid318Beta-secretase 13.4.23.460.460
3imgBZ2Pantothenate synthetase6.3.2.10.460
3ivxFG6Pantothenate synthetase6.3.2.10.460
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.460
4jlm1NNDeoxycytidine kinase2.7.1.740.460
4yau2AMNADPH--cytochrome P450 reductase/0.460
1hb3SCVIsopenicillin N synthase1.21.3.10.459
1lrkUD1UDP-glucose 4-epimerase5.1.3.20.459
1t4u81AProthrombin3.4.21.50.459
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.459
2vuuNAPNitrogen metabolite repression protein nmrA/0.459
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.459
4ilx1EZCarbonic anhydrase 24.2.1.10.459
4tldAGSCircadian clock protein kinase KaiC2.7.11.10.459
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1obnASVIsopenicillin N synthase1.21.3.10.458
1ypeUIPProthrombin3.4.21.50.458
2jb4A14Isopenicillin N synthase1.21.3.10.458
2x94X94Angiotensin-converting enzyme3.4.15.10.458
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.458
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.458
3pqbVGPPutative oxidoreductase/0.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
4k9oTPPBenzoylformate decarboxylase4.1.1.70.458
4kp5E1FCarbonic anhydrase 124.2.1.10.458
1rneC60Renin3.4.23.150.457
1tllFMNNitric oxide synthase, brain1.14.13.390.457
2whqHI6Acetylcholinesterase3.1.1.70.457
3bk2U5PRibonuclease J/0.457
3ivgFG5Pantothenate synthetase6.3.2.10.457
3qe2FMNNADPH--cytochrome P450 reductase/0.457
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.457
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.457
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4jqh1MFAlr2278 protein/0.457
4yaw2AMNADPH--cytochrome P450 reductase/0.457
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1pqc444Oxysterols receptor LXR-beta/0.456
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.456
2g20L1ARenin3.4.23.150.456
2iviACWIsopenicillin N synthase1.21.3.10.456
2qw034Z4-chlorobenzoyl CoA ligase/0.456
2zevIPEGeranylgeranyl pyrophosphate synthase/0.456
3junAKDPhenazine biosynthesis protein A/B/0.456
3p0fBAUUridine phosphorylase 22.4.2.30.456
3phjDHKShikimate dehydrogenase (NADP(+))/0.456
3t84SG6Carbonic anhydrase 24.2.1.10.456
4e32DWNMethyltransferase/0.456
4tmbFMNOld yellow enzyme/0.456
1xm1GAHProthrombin3.4.21.50.455
2anmCDOProthrombin3.4.21.50.455
2dxdANPNucleoside diphosphate kinase2.7.4.60.455
2w6cBM4Acetylcholinesterase3.1.1.70.455
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3hlwCE3Beta-lactamase/0.455
3p62FMNPentaerythritol tetranitrate reductase/0.455
4ayy9MXProthrombin3.4.21.50.455
4iae1DXAlr2278 protein/0.455
1h61PDNPentaerythritol tetranitrate reductase/0.454
1i8zINLCarbonic anhydrase 24.2.1.10.454
1rj6AZMCarbonic anhydrase 144.2.1.10.454
1toiHCIAspartate aminotransferase2.6.1.10.454
2gjnFMNNitronate monooxygenase1.13.12.160.454
2x7tWZBCarbonic anhydrase 24.2.1.10.454
2xviFADPutative flavin-containing monooxygenase/0.454
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.454
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.454
3iocA5DPantothenate synthetase6.3.2.10.454
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.454
4b65FADL-ornithine N(5)-monooxygenase/0.454
4de00JBBeta-lactamase/0.454
4eqrCOACoenzyme A disulfide reductase/0.454
4h0vNADIota toxin component Ia/0.454
4k0tD9ZCarbonic anhydrase 24.2.1.10.454
4pgtGBXGlutathione S-transferase P2.5.1.180.454
4rn615UProthrombin3.4.21.50.454
1d3dBZTProthrombin3.4.21.50.453
1g6kNADGlucose 1-dehydrogenase1.1.1.470.453
1m13HYFNuclear receptor subfamily 1 group I member 2/0.453
2il2LIXRenin3.4.23.150.453
3coz54HPantothenate synthetase6.3.2.10.453
3e6eDCSAlanine racemase/0.453
3rpeFADPutative modulator of drug activity/0.453
4tyqAP5Adenylate kinase/0.453
4yao2AMNADPH--cytochrome P450 reductase/0.453
1i9qIOFCarbonic anhydrase 24.2.1.10.452
1krrACOGalactoside O-acetyltransferase2.3.1.180.452
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1tehNADAlcohol dehydrogenase class-31.1.1.10.452
2bn4FMNNADPH--cytochrome P450 reductase/0.452
2ckmAA7Acetylcholinesterase3.1.1.70.452
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.452
2xugTZ4Acetylcholinesterase3.1.1.70.452
2ylrNAPPhenylacetone monooxygenase1.14.13.920.452
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3dazMZMCarbonic anhydrase 24.2.1.10.452
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.452
3k8q22APurine nucleoside phosphorylase2.4.2.10.452
3pftFMNFlavin reductase/0.452
4bftZVTPantothenate kinase2.7.1.330.452
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.452
4ycoFMNtRNA-dihydrouridine(16) synthase/0.452
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.452
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
1d9i00PProthrombin3.4.21.50.451
1lc3NADBiliverdin reductase A1.3.1.240.451
1qjfACSIsopenicillin N synthase1.21.3.10.451
1qtiGNTAcetylcholinesterase3.1.1.70.451
1r58AO5Methionine aminopeptidase 2/0.451
1u1gBBBUridine phosphorylase2.4.2.30.451
1ut6A8NAcetylcholinesterase3.1.1.70.451
1xe65FPPlasmepsin-23.4.23.390.451
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.451
2jh5895Prothrombin3.4.21.50.451
2xveFADPutative flavin-containing monooxygenase/0.451
3p1799PProthrombin3.4.21.50.451
3rbaCODPhosphopantetheine adenylyltransferase/0.451
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.451
4yal2AMNADPH--cytochrome P450 reductase/0.451
1gpeFADGlucose oxidase1.1.3.40.450
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.450
1r2jFADFkbI/0.450
2wehFB1Carbonic anhydrase 24.2.1.10.450
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.450
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3oysOYSCarbonic anhydrase 24.2.1.10.450
4g3jVNTLanosterol 14-alpha-demethylase/0.450
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.450
4m2vBZ1Carbonic anhydrase 24.2.1.10.450
4zj8SUVOrexin receptor type 1/0.450
1d6w00RProthrombin3.4.21.50.449
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.449
1wuaAP8Actin, alpha skeletal muscle/0.449
1yplRA8Prothrombin3.4.21.50.449
2pncCLUPrimary amine oxidase, liver isozyme/0.449
2vprTDCTetracycline repressor protein class H/0.449
3ai3NDPNADPH-sorbose reductase/0.449
3b4fTUOCarbonic anhydrase 24.2.1.10.449
3ddnHPVD-3-phosphoglycerate dehydrogenase1.1.1.950.449
3eksCY9Actin-5C/0.449
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.449
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.449
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.449
3nutSAHPrecorrin-3 methylase/0.449
4b1rITCTetracycline repressor protein class D/0.449
4b66FADL-ornithine N(5)-monooxygenase/0.449
4iah1DXAlr2278 protein/0.449
4zweDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
1cjtFOKAdenylate cyclase type 2/0.448
1cjtFOKAdenylate cyclase type 5/0.448
1gj4132Prothrombin3.4.21.50.448
1h22E10Acetylcholinesterase3.1.1.70.448
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.448
1thyUMPThymidylate synthase/0.448
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.448
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.448
2vn1FK5Peptidylprolyl isomerase/0.448
2y60M8FIsopenicillin N synthase1.21.3.10.448
2ym1NAPPhenylacetone monooxygenase1.14.13.920.448
3c3xNAPEugenol synthase 11.1.1.3180.448
3imgBZ3Pantothenate synthetase6.3.2.10.448
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.448
3ixp834Ecdysone receptor/0.448
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.448
3mhlJ71Carbonic anhydrase 24.2.1.10.448
3own3OWRenin3.4.23.150.448
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.448
4awtFMNNADH:flavin oxidoreductase Sye1/0.448
4itoMPXCarbonic anhydrase 24.2.1.10.448
4ke11R6Beta-secretase 13.4.23.460.448
1gky5GPGuanylate kinase2.7.4.80.447
1hb1OCVIsopenicillin N synthase1.21.3.10.447
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1vf2GTXGlutathione S-transferase 32.5.1.180.447
1vf3GDNGlutathione S-transferase 32.5.1.180.447
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.447
2qimZEAClass 10 plant pathogenesis-related protein/0.447
2zhq27UProthrombin3.4.21.50.447
2ziq26UProthrombin3.4.21.50.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3eufBAUUridine phosphorylase 1/0.447
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.447
3phiNDPShikimate dehydrogenase (NADP(+))/0.447
4asuADPATP synthase subunit alpha, mitochondrial/0.447
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.447
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.447
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.447
4l96LRGPeroxisome proliferator-activated receptor gamma/0.447
17gsGTXGlutathione S-transferase P2.5.1.180.446
1e66HUXAcetylcholinesterase3.1.1.70.446
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.446
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.446
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.446
2gjlFMNNitronate monooxygenase1.13.12.160.446
2v16C47Renin3.4.23.150.446
2v3wTPPBenzoylformate decarboxylase4.1.1.70.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2wejFB2Carbonic anhydrase 24.2.1.10.446
3dbuD8WCarbonic anhydrase 24.2.1.10.446
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.446
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.446
3pm1ETHTH-type transcriptional regulator QacR/0.446
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.446
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.446
4dh0MR8Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.446
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.446
4ohwATPProtein clpf-1/0.446
4wriOKAOkadaic acid binding protein 2-alpha/0.446
5cb3APRO-acetyl-ADP-ribose deacetylase/0.446
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.446
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.446
1a7xFKAPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.445
1bn3AL6Carbonic anhydrase 24.2.1.10.445
1cilETSCarbonic anhydrase 24.2.1.10.445
1l8qADPChromosomal replication initiator protein DnaA/0.445
1w76GNTAcetylcholinesterase3.1.1.70.445
1x1bSAHC-20 methyltransferase/0.445
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.445
1ypmRA4Prothrombin3.4.21.50.445
2gevCOKPantothenate kinase2.7.1.330.445
3eft3BSCarbonic anhydrase 24.2.1.10.445
3fcjFADNitroalkane oxidase1.7.3.10.445
3iu8T03Methionine aminopeptidase 2/0.445
3m96E38Carbonic anhydrase 24.2.1.10.445
3t82SG4Carbonic anhydrase 24.2.1.10.445
3vydVYDRenin3.4.23.150.445
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.445
4b63NAPL-ornithine N(5)-monooxygenase/0.445
4df2FMNNADPH dehydrogenase/0.445
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.445
4ihl1F514-3-3 protein zeta/delta/0.445
4pzrCOAHistone acetyltransferase p300/0.445
1bk0ACVIsopenicillin N synthase1.21.3.10.444
1hncGDNGlutathione S-transferase Mu 22.5.1.180.444
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.444
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.444
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.444
2nr4FMNConserved protein/0.444
2wf2ZY2Beta-secretase 13.4.23.460.444
2zhw12UProthrombin3.4.21.50.444
3g70A5TRenin3.4.23.150.444
3m40J45Carbonic anhydrase 24.2.1.10.444
3po6DT9Carbonic anhydrase 24.2.1.10.444
3qj0QI3Botulinum neurotoxin type A3.4.24.690.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.444
4b66NAPL-ornithine N(5)-monooxygenase/0.444
4ejvLCLTranscriptional regulator TcaR/0.444
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.444
4i0h1BLBeta-secretase 13.4.23.460.444
4k13ETSCarbonic anhydrase 24.2.1.10.444
4lh71X8DNA ligase/0.444
4mlp2CXCryptochrome-2/0.444
4relKMPGlycosyltransferase/0.444
4uy6SAHHistidine N-alpha-methyltransferase/0.444
4wecNADShort chain dehydrogenase/0.444
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.444
5fl49FKCarbonic anhydrase 94.2.1.10.444
4xnw2IDP2Y purinoceptor 1/0.444
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1h50FMNPentaerythritol tetranitrate reductase/0.443
1icqFMN12-oxophytodienoate reductase 11.3.1.420.443
1mu8CDBProthrombin3.4.21.50.443
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.443
1sm4FADFerredoxin--NADP reductase/0.443
1towCRZFatty acid-binding protein, adipocyte/0.443
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1xq04TRCarbonic anhydrase 24.2.1.10.443
1ypgUIRProthrombin3.4.21.50.443
1zgbA1EAcetylcholinesterase3.1.1.70.443
2cndFADNitrate reductase [NADH]1.7.1.10.443
2gtbAZPOrf1ab polyprotein/0.443
2xuiTZ5Acetylcholinesterase3.1.1.70.443
3b6zCO7Enoyl reductase LovC10.443
3dcsMZMCarbonic anhydrase 24.2.1.10.443
3elePLPAminotransferase/0.443
3l6jZ90Alr2278 protein/0.443
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.443
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.443
4de3DN8Beta-lactamase/0.443
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.443
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.443
4jicFMNGTN Reductase/0.443
4nieNBHNuclear receptor ROR-gamma/0.443
4rvfTYDD-mycarose 3-C-methyltransferase/0.443
5hg0SAMPantothenate synthetase/0.443
1e1qANPATP synthase subunit alpha, mitochondrial/0.442
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.442
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.442
1nzq162Prothrombin3.4.21.50.442
1qiqACCIsopenicillin N synthase1.21.3.10.442
1sb1165Prothrombin3.4.21.50.442
1wuuANPGalactokinase2.7.1.60.442
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.442
20gsCBDGlutathione S-transferase P2.5.1.180.442
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.442
2gqaFMNNADH:flavin oxidoreductase Sye1/0.442
2ifaFMNUncharacterized protein/0.442
2oz57XYUncharacterized protein/0.442
2rqfJH3Hemolymph juvenile hormone binding protein/0.442
2ylzFADPhenylacetone monooxygenase1.14.13.920.442
2z1qFADAcyl-CoA dehydrogenase/0.442
2zvcSAHPrecorrin-3 C17-methyltransferase/0.442
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.442
3d9zD9ZCarbonic anhydrase 24.2.1.10.442
3h3t16HCollagen type IV alpha-3-binding protein/0.442
3qwc98PProthrombin3.4.21.50.442
4bf19FKCarbonic anhydrase 24.2.1.10.442
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.442
4dbs0HVAldo-keto reductase family 1 member C3/0.442
4dpy2P0Mevalonate diphosphate decarboxylase/0.442
4exg916Beta-secretase 13.4.23.460.442
4itp1GDCarbonic anhydrase 24.2.1.10.442
4ixd1HVIntegrin alpha-L/0.442
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
1gtrATPGlutamine--tRNA ligase6.1.1.180.441
1if7SBRCarbonic anhydrase 24.2.1.10.441
1m4iCOAAminoglycoside 2'-N-acetyltransferase2.3.10.441
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.441
1ppjANYCytochrome b/0.441
1sq5ADPPantothenate kinase2.7.1.330.441
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2fmoFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.441
2futH1SHeparin and heparin-sulfate lyase/0.441
2oapANPType II secretion system protein (GspE-2)/0.441
2uxoTACHTH-type transcriptional regulator TtgR/0.441
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.441
2xukTZ5Acetylcholinesterase3.1.1.70.441
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.441
3k1wBFXRenin3.4.23.150.441
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.441
3ojxFMNNADPH--cytochrome P450 reductase/0.441
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.441
3s9tE49Carbonic anhydrase 24.2.1.10.441
3zoiM2WIsopenicillin N synthase1.21.3.10.441
4bfxZVXPantothenate kinase2.7.1.330.441
4du82P0Mevalonate diphosphate decarboxylase/0.441
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4gv8DUPDUTPase/0.441
4ipw1G7Mycocyclosin synthase1.14.21.90.441
4ise1FWGlucokinase2.7.1.20.441
4n3l2FNProthrombin3.4.21.50.441
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
5fmmMGTPolymerase basic protein 2/0.441
1acjTHAAcetylcholinesterase3.1.1.70.440
1b2lNDCAlcohol dehydrogenase1.1.1.10.440
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.440
1g54FFBCarbonic anhydrase 24.2.1.10.440
1jwtBLIProthrombin3.4.21.50.440
1odcA8BAcetylcholinesterase3.1.1.70.440
1tojHCIAspartate aminotransferase2.6.1.10.440
1xddAAYIntegrin alpha-L/0.440
1z44FMNNADPH dehydrogenase/0.440
2a5kAZPReplicase polyprotein 1ab3.4.220.440
2ab8MTPAdenosine kinase2.7.1.200.440
2cf8ESHProthrombin3.4.21.50.440
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.440
2lbaCHOFatty acid binding protein 6/0.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2zc922UProthrombin3.4.21.50.440
3b1dPLSBetaC-S lyase/0.440
3dd0EZLCarbonic anhydrase 24.2.1.10.440
3ha5SFGHydroxymycolate synthase MmaA42.1.10.440
3ni5C1HCarbonic anhydrase 24.2.1.10.440
3oadLPORenin3.4.23.150.440
3qykIE2Carbonic anhydrase 24.2.1.10.440
3rq8AP5ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.440
4c717RD3-oxoacyl-ACP synthase/0.440
4iawLIZNeutrophil gelatinase-associated lipocalin/0.440
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.440
4m83ERYOleandomycin glycosyltransferase2.4.10.440
4q0kGA3Phytohormone-binding protein/0.440
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.440