sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1xts | GTP | GTP-binding protein Rheb |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1xts | GTP | GTP-binding protein Rheb | / | 1.000 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.580 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.576 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.531 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.527 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.527 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.522 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.515 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.514 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.513 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.512 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.507 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.503 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.501 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.497 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.494 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.491 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.490 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.490 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.488 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.486 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.485 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.483 | |
| 3ddc | GNP | GTPase HRas | / | 0.483 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.477 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.476 | |
| 4nyi | GNP | GTPase HRas | / | 0.476 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.474 | |
| 4nyj | GNP | GTPase HRas | / | 0.474 | |
| 3lbn | GNP | GTPase HRas | / | 0.473 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.472 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.472 | |
| 3oiu | GNP | GTPase HRas | / | 0.469 | |
| 3oiv | GNP | GTPase HRas | / | 0.469 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.468 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.468 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.467 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.466 | |
| 2rge | GNP | GTPase HRas | / | 0.466 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.465 | |
| 4dlt | GNP | GTPase HRas | / | 0.465 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.465 | |
| 4k81 | GTP | GTPase HRas | / | 0.464 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.463 | |
| 4mit | GTP | Rho-related protein racC | / | 0.463 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.462 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.461 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.461 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.459 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.458 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.453 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.453 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.452 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.452 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.452 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.451 | |
| 4xvr | GNP | GTPase HRas | / | 0.451 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.449 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.448 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.448 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.446 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.446 | |
| 3v4f | GNP | GTPase HRas | / | 0.446 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.445 | |
| 3lbh | GNP | GTPase HRas | / | 0.445 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.444 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.443 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.443 | |
| 5b2z | GNP | GTPase HRas | / | 0.443 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.442 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.442 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.442 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.441 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 3l8y | GNP | GTPase HRas | / | 0.440 |