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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1xs4DCPdCTP deaminase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1xs4DCPdCTP deaminase/1.000
2v9xDUTdCTP deaminase/0.586
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.529
4a6aTTPdCTP deaminase3.5.4.130.514
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.506
3h3r14HCollagen type IV alpha-3-binding protein/0.499
3rq8AP5ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.498
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.496
3qt62P0Mevalonate diphosphate decarboxylase/0.496
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.494
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.493
2rqfJH3Hemolymph juvenile hormone binding protein/0.492
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.491
3bk2U5PRibonuclease J/0.491
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.490
3juqAKDPhenazine biosynthesis protein A/B/0.490
4m83ERYOleandomycin glycosyltransferase2.4.10.489
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.488
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.488
3qviK95HAP protein/0.488
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.488
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.486
2zbaZBATrichothecene 3-O-acetyltransferase/0.485
3c15FOKAdenylate cyclase type 2/0.485
3c15FOKAdenylate cyclase type 5/0.485
3h0bB35Beta-secretase 13.4.23.460.485
2oapANPType II secretion system protein (GspE-2)/0.484
4du82P0Mevalonate diphosphate decarboxylase/0.484
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.484
1ay0TPPTransketolase 12.2.1.10.483
1udaUFGUDP-glucose 4-epimerase5.1.3.20.483
3fr5I4AFatty acid-binding protein, adipocyte/0.483
4gsuDWZL,D-transpeptidase 22.3.20.483
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.483
1culFOKAdenylate cyclase type 2/0.482
1culFOKAdenylate cyclase type 5/0.482
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.482
3bnkFMNFlavoredoxin/0.482
4i1nFOLDihydrofolate reductase1.5.1.30.482
3junAKDPhenazine biosynthesis protein A/B/0.481
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.481
4dbzNDPPutative ketoacyl reductase1.3.10.481
4g95OAGDihydrofolate reductase1.5.1.30.481
1u71MXADihydrofolate reductase1.5.1.30.480
3gwfNAPCyclohexanone monooxygenase/0.480
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.479
5cyoGDPSeptin-9/0.479
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
1txtCAAHMG-CoA synthase/0.478
2cbrA80Cellular retinoic acid-binding protein 1/0.478
2w9hTOPDihydrofolate reductase1.5.1.30.478
4dfg0JVGag-Pol polyprotein3.4.23.160.478
4kb9G79Protease/0.478
5d3qGDPDynamin-13.6.5.50.478
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
3m2rCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.477
3m2rCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.477
3tog079Gag-Pol polyprotein2.7.7.490.477
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.476
2p5cSAHDiphthine synthase/0.476
4fxy0W2Neurolysin, mitochondrial3.4.24.160.476
4jc51K5Stimulator of interferon genes protein/0.476
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.475
2dxvSAHDiphthine synthase/0.475
2ejzSAHDiphthine synthase/0.475
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.475
3ixp834Ecdysone receptor/0.475
4a862ANMajor pollen allergen Bet v 1-A/0.475
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.474
1w4xFADPhenylacetone monooxygenase1.14.13.920.474
2fj1CTCTetracycline repressor protein class D/0.474
3ad9NADSubunit alpha of sarocosine oxidase/0.474
3zeiAWHO-acetylserine sulfhydrylase/0.474
1p0pBCHCholinesterase3.1.1.80.473
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.473
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.473
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.473
3rdiCMPcAMP-activated global transcriptional regulator CRP/0.473
1bdlIM1Gag-Pol polyprotein3.4.23.160.472
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.472
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.472
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.472
2hr8SAHDiphthine synthase/0.472
2vq7NAPPutative flavin-containing monooxygenase/0.472
2x7hPFNProstaglandin reductase 310.472
4fse0VABeta-secretase 13.4.23.460.472
1u1gBBBUridine phosphorylase2.4.2.30.471
1vgrCOAFormyl-CoA:oxalate CoA-transferase/0.471
2j9lATPH(+)/Cl(-) exchange transporter 5/0.471
2p2mPRXAcetyl-coenzyme A synthetase/0.471
2we3DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase/0.471
2ym1FADPhenylacetone monooxygenase1.14.13.920.471
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3juqAJDPhenazine biosynthesis protein A/B/0.471
4ke11R6Beta-secretase 13.4.23.460.471
4nbwNADShort-chain dehydrogenase/reductase SDR/0.471
4nv10FXFormyl transferase/0.471
1mjbACOHistone acetyltransferase ESA1/0.470
2os1BB2Peptide deformylase/0.470
2qbuSAHPrecorrin-2 methyltransferase/0.470
3fkqATPNtrC-like two-domain protein/0.470
1j78VDYVitamin D-binding protein/0.469
1qorNDPQuinone oxidoreductase 1/0.469
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.469
2ge3ACOProbable acetyltransferase/0.469
2ien017Gag-Pol polyprotein3.4.23.160.469
3ekuCY9Actin-5C/0.469
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.469
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.469
4xjcTTPdCTP deaminase/0.469
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.469
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.469
1m0b0ZQGag-Pol polyprotein3.4.23.160.468
1mrqSTRAldo-keto reductase family 1 member C1/0.468
2c29NAPDihydroflavonol 4-reductase/0.468
2g1r3IGRenin3.4.23.150.468
2xtnGTPGTPase IMAP family member 2/0.468
3imgBZ2Pantothenate synthetase6.3.2.10.468
4idpGNPAtlastin-13.6.50.468
4m4922YL-lactate dehydrogenase A chain1.1.1.270.468
1dr3TAPDihydrofolate reductase1.5.1.30.467
2c20NADUDP-glucose 4-epimerase/0.467
2dxwSAHDiphthine synthase/0.467
2i7pACOPantothenate kinase 32.7.1.330.467
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.467
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.467
3toh079Gag-Pol polyprotein2.7.7.490.467
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.466
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.466
1t2cNAIL-lactate dehydrogenase1.1.1.270.466
1vf2GTXGlutathione S-transferase 32.5.1.180.466
1w6hTITPlasmepsin-23.4.23.390.466
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
2eglSAHDiphthine synthase/0.466
2iyfERYOleandomycin glycosyltransferase2.4.10.466
3wleNAD(R)-specific carbonyl reductase/0.466
4a83DXCMajor pollen allergen Bet v 1-A/0.466
4dymIYZActivin receptor type-12.7.11.300.466
4loi1YCStimulator of interferon genes protein/0.466
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.466
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.465
1dr5NAPDihydrofolate reductase1.5.1.30.465
1mvsDTMDihydrofolate reductase1.5.1.30.465
1obnASVIsopenicillin N synthase1.21.3.10.465
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.465
1vyqDUXDeoxyuridine 5'-triphosphate nucleotidohydrolase/0.465
1yw8A75Methionine aminopeptidase 2/0.465
2a94AP0L-lactate dehydrogenase1.1.1.270.465
2huqSAHDiphthine synthase/0.465
4dpuAGSMevalonate diphosphate decarboxylase/0.465
4ewo996Beta-secretase 13.4.23.460.465
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.465
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.465
4wrkDUPDUTPase/0.465
1mxfMTXPutative pteridine reductase 2/0.464
2en5SAHDiphthine synthase/0.464
2g1o2IGRenin3.4.23.150.464
2g247IGRenin3.4.23.150.464
2oegUPGUDP-glucose pyrophosphorylase/0.464
2p6kSAHDiphthine synthase/0.464
3d2mCOAAmino-acid acetyltransferase/0.464
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.464
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.464
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.464
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.464
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.463
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.463
1cjtFOKAdenylate cyclase type 2/0.463
1cjtFOKAdenylate cyclase type 5/0.463
1qf5RPLAdenylosuccinate synthetase/0.463
1z2nADPInositol-tetrakisphosphate 1-kinase2.7.1.1340.463
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.463
2ep7NADGlyceraldehyde-3-phosphate dehydrogenase/0.463
2j4qTTPdCTP deaminase/0.463
2lfoGCHFatty acid-binding protein, liver/0.463
2pj4414Carboxypeptidase B/0.463
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.463
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.463
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.463
3rzpPRFNADPH-dependent 7-cyano-7-deazaguanine reductase/0.463
3v3qTMYNuclear receptor subfamily 4 group A member 1/0.463
4dptAGSMevalonate diphosphate decarboxylase/0.463
4s1iPLPPyridoxal kinase, putative/0.463
1mv8GDXGDP-mannose 6-dehydrogenase1.1.1.1320.462
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.462
1ykdCMPAdenylate cyclase/0.462
2dekSAHDiphthine synthase/0.462
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.462
2vj9VG7Beta-secretase 13.4.23.460.462
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.462
3c14FOKAdenylate cyclase type 2/0.462
3c14FOKAdenylate cyclase type 5/0.462
3f3sNADLambda-crystallin homolog/0.462
3h2sNDPPutative NADH-flavin reductase/0.462
3u8l09QAcetylcholine-binding protein/0.462
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.462
5dp2NAPCurF/0.462
1dliUDXUDP-glucose 6-dehydrogenase/0.461
1dr2TAPDihydrofolate reductase1.5.1.30.461
1hbvGANGag-Pol polyprotein/0.461
1k8y13PTryptophan synthase alpha chain/0.461
1rf7DHFDihydrofolate reductase1.5.1.30.461
2cjfRP43-dehydroquinate dehydratase4.2.1.100.461
2g1n1IGRenin3.4.23.150.461
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.461
2w3bNDPDihydrofolate reductase1.5.1.30.461
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.461
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.461
3lqfNADGalactitol dehydrogenase/0.461
3ohh3HHBeta-secretase 13.4.23.460.461
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.461
3rqqBA3ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.461
4ipw1G7Mycocyclosin synthase1.14.21.90.461
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.461
5irnADPNucleotide binding oligomerization domain containing 2/0.461
1jqdSAHHistamine N-methyltransferase2.1.1.80.460
1kfbIGPTryptophan synthase alpha chain/0.460
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.460
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.460
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.460
2g1s4IGRenin3.4.23.150.460
2hutSAHDiphthine synthase/0.460
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.460
2xhd7T9Glutamate receptor 2/0.460
3h3qH13Collagen type IV alpha-3-binding protein/0.460
3r4b74TGag-Pol polyprotein/0.460
3tn8F18Cyclin-dependent kinase 92.7.11.220.460
3u9eCOALmo1369 protein/0.460
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.460
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.460
1juvNDPDihydrofolate reductase1.5.1.30.459
1rx8NAPDihydrofolate reductase1.5.1.30.459
2cv1ATPGlutamate--tRNA ligase6.1.1.170.459
2dv7SAHDiphthine synthase/0.459
2eldSAHDiphthine synthase/0.459
2fb2SAMGTP 3',8-cyclase4.1.99.180.459
2gtbAZPOrf1ab polyprotein/0.459
2rh9IGPTryptophan synthase alpha chain/0.459
2xtkAZMClass III chitinase ChiA1/0.459
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.459
3nxxNDPDihydrofolate reductase1.5.1.30.459
3qeoLLTDeoxycytidine kinase2.7.1.740.459
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.459
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.459
3zh8C58Protein kinase C iota type2.7.11.130.459
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.459
4an4DUDPutative glycosyl transferase/0.459
4exg916Beta-secretase 13.4.23.460.459
1h73ANPHomoserine kinase2.7.1.390.458
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.458
1pqc444Oxysterols receptor LXR-beta/0.458
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.458
1vceSAHDiphthine synthase/0.458
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.458
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.458
2bxqIMNSerum albumin/0.458
2ctsCOACitrate synthase, mitochondrial2.3.3.10.458
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.458
2ffqGSPRas-related protein Rab-6B/0.458
2jt2C90UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.458
2p5fSAHDiphthine synthase/0.458
2pbzATPUncharacterized protein/0.458
2pchSAHDiphthine synthase/0.458
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.458
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
2zrjAGSProtein RecA/0.458
3cluFADElectron transfer flavoprotein subunit alpha/0.458
3kpbSAMUncharacterized protein MJ0100/0.458
3vmmP0DAlanine--anticapsin ligase/0.458
4a8v2ANMajor pollen allergen Bet v 1-J/0.458
4dpy2P0Mevalonate diphosphate decarboxylase/0.458
4dz2FK5Peptidyl-prolyl cis-trans isomerase/0.458
4i8zG08Gag-Pol polyprotein3.4.23.160.458
4qxr1YEStimulator of interferon genes protein/0.458
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.458
1jqiCAAShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.457
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.457
1r2jFADFkbI/0.457
1szgFNSCytochrome b2, mitochondrial1.1.2.30.457
1xddAAYIntegrin alpha-L/0.457
2bxoOPBSerum albumin/0.457
2e0nSAHPrecorrin-2 C20-methyltransferase/0.457
2ek7SAHDiphthine synthase/0.457
2el0SAHDiphthine synthase/0.457
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.457
2p20PRXAcetyl-coenzyme A synthetase/0.457
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3e39FMNNitroreductase/0.457
3oqkS52Renin3.4.23.150.457
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.457
4blrUTPNTPase P4/0.457
4ef4C2EStimulator of interferon genes protein/0.457
4pzrCOAHistone acetyltransferase p300/0.457
4twnB96Ephrin type-A receptor 32.7.10.10.457
1a8rGTPGTP cyclohydrolase 13.5.4.160.456
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.456
1qoqIGPTryptophan synthase alpha chain/0.456
1w13SM1Urokinase-type plasminogen activator3.4.21.730.456
2b53D23Cyclin-dependent kinase 22.7.11.220.456
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.456
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.456
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.456
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.456
2o7oDXTTetracycline repressor protein class D/0.456
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.456
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.456
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.456
3junAJDPhenazine biosynthesis protein A/B/0.456
3phiNDPShikimate dehydrogenase (NADP(+))/0.456
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.456
4djaFAD(6-4) photolyase/0.456
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.456
4jicFMNGTN Reductase/0.456
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.456
4m6jNDPDihydrofolate reductase1.5.1.30.456
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.456
4oztP1AEcdysone receptor, putative/0.456
5c3jUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.456
5c3jUQ1Succinate dehydrogenase cytochrome b560/0.456
5c4nNAPPrecorrin-6A reductase1.3.1.540.456
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.456
1gj4132Prothrombin3.4.21.50.455
1n3rGTPGTP cyclohydrolase 13.5.4.160.455
1tqf32PBeta-secretase 13.4.23.460.455
2a9y26AAdenosine kinase2.7.1.200.455
2bsxNOSPurine nucleoside phosphorylase/0.455
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.455
2e8qSAHDiphthine synthase/0.455
2eniSAHDiphthine synthase/0.455
2p6lSAHDiphthine synthase/0.455
2x3jATPAcsD/0.455
3fhxPLPPyridoxal kinase2.7.1.350.455
3in6FMNUncharacterized protein/0.455
3iocA5DPantothenate synthetase6.3.2.10.455
3mtfA3FActivin receptor type-12.7.11.300.455
4c4oNADSADH/0.455
4eb7PLPCysteine desulfurase IscS 2/0.455
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.455
4l1fCOSAcyl-CoA dehydrogenase domain protein/0.455
4v2gITCTetracycline repressor protein class D/0.455
4xvuATPATPase GET3/0.455
1daaPLPD-alanine aminotransferase2.6.1.210.454
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.454
1kqfMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.454
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.454
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.454
1thyUMPThymidylate synthase/0.454
1x2hLPALipoate-protein ligase A6.3.1.200.454
2amt1AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.454
2b58COADiamine acetyltransferase 1/0.454
2dshSAHDiphthine synthase/0.454
2dv4SAHDiphthine synthase/0.454
2e1mFADL-glutamate oxidase/0.454
2ejkSAHDiphthine synthase/0.454
2emuSAHDiphthine synthase/0.454
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.454
2owvSAHDiphthine synthase/0.454
2p6iSAHDiphthine synthase/0.454
2rlcCHDCholoylglycine hydrolase3.5.1.240.454
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.454
2xpuTDCTetracycline repressor protein class D/0.454
2ztsADPUncharacterized protein/0.454
3aosJH2Hemolymph juvenile hormone binding protein/0.454
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.454
3vilSA0Beta-glucosidase/0.454
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.454
4bfzZVZPantothenate kinase2.7.1.330.454
4e03ADPPlasmid partitioning protein ParF/0.454
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.454
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.454
4opiFDAConserved Archaeal protein/0.454
5c1mCLRMu-type opioid receptor/0.454
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.453
1fy7COAHistone acetyltransferase ESA1/0.453
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.453
1okkGCPSignal recognition particle protein/0.453
1okkGCPSignal recognition particle receptor FtsY/0.453
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.453
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.453
1rpnNDPGDP-mannose 4,6-dehydratase/0.453
1w1wAGSStructural maintenance of chromosomes protein 1/0.453
1w5tANPORC1-type DNA replication protein 2/0.453
1wngSAHDiphthine synthase/0.453
1yb5NAPQuinone oxidoreductase1.6.5.50.453
2gv8NDPThiol-specific monooxygenase1.14.130.453
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.453
2npxNADNADH peroxidase1.11.1.10.453
2oahQINBeta-secretase 13.4.23.460.453
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.453
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.453
2vkeTACTetracycline repressor protein class D/0.453
2x93X93Angiotensin-converting enzyme3.4.15.10.453
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.453
2zshGA3Gibberellin receptor GID1A30.453
3c1y2BADNA integrity scanning protein DisA/0.453
3i0pNADMalate dehydrogenase, putative/0.453
3lzs017Gag-Pol polyprotein3.4.23.160.453
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.453
3sp9IL2Peroxisome proliferator-activated receptor delta/0.453
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.453
3wb2YGPUncharacterized protein MJ0488/0.453
4bf9FMNtRNA-dihydrouridine(16) synthase/0.453
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4uocNCNCinA-like protein/0.453
1esvLARActin, alpha skeletal muscle/0.452
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.452
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.452
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1jmhUMPThymidylate synthase/0.452
1njfADPDNA polymerase III subunit tau2.7.7.70.452
1nzfUPGDNA beta-glucosyltransferase/0.452
1pjcNADAlanine dehydrogenase/0.452
1pq944BOxysterols receptor LXR-beta/0.452
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.452
1zrzBI1Protein kinase C iota type2.7.11.130.452
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.452
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.452
2e16SAHDiphthine synthase/0.452
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
2emrSAHDiphthine synthase/0.452
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.452
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.452
2p8hMY9Beta-secretase 13.4.23.460.452
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.452
2vprTDCTetracycline repressor protein class H/0.452
2w6qOA5Biotin carboxylase6.3.4.140.452
3a0tADPSensor histidine kinase/0.452
3b9lAZZSerum albumin/0.452
3e23SAMUncharacterized protein/0.452
3f63GTXGlutathione transferase GST1-4/0.452
3qizQI2Botulinum neurotoxin type A3.4.24.690.452
4bb3KKAIsopenicillin N synthase1.21.3.10.452
4cukNAID-lactate dehydrogenase/0.452
4fco0U4Beta-secretase 13.4.23.460.452
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.452
4tlxFDAKtzI/0.452
4ttcFMNIodotyrosine deiodinase 1/0.452
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.451
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1l7x700Glycogen phosphorylase, liver form2.4.1.10.451
1m78NDPDihydrofolate reductase1.5.1.30.451
1mjaCOAHistone acetyltransferase ESA1/0.451
1pagFMPAntiviral protein I3.2.2.220.451
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.451
1udcUFMUDP-glucose 4-epimerase5.1.3.20.451
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.451
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2bn4FMNNADPH--cytochrome P450 reductase/0.451
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.451
2dsiSAHDiphthine synthase/0.451
2ek2SAHDiphthine synthase/0.451
2f81017Gag-Pol polyprotein3.4.23.160.451
2iko7IGRenin3.4.23.150.451
2pb4SAHDiphthine synthase/0.451
2pb6SAHDiphthine synthase/0.451
2v16C47Renin3.4.23.150.451
2vjmCOAFormyl-CoA:oxalate CoA-transferase/0.451
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.451
2z52H23Geranylgeranyl pyrophosphate synthase/0.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3k5uPFQAurora kinase A2.7.11.10.451
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.451
3uylTYDProbable NDP-rhamnosyltransferase/0.451
4bgg844Activin receptor type-12.7.11.300.451
4dc0NDPPutative ketoacyl reductase1.3.10.451
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.451
4lcjNADC-terminal-binding protein 2/0.451
4lol1YEStimulator of interferon genes protein/0.451
4pb25UDNucleoside permease/0.451
4qvbF42F420H(2)-dependent reductase Rv11551.4.3.50.451
4ryvZEAProtein LlR18A/0.451
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.451
4x9nFADUncharacterized protein MG039 homolog/0.451
4ycpFMNtRNA-dihydrouridine(16) synthase/0.451
5cflC2EStimulator of interferon genes protein/0.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
5fkmTDCTetracycline repressor protein class D/0.451
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.451
1eioGCHGastrotropin/0.450
1f20FADNitric oxide synthase, brain1.14.13.390.450
1h65GDPTranslocase of chloroplast 343.6.50.450
1rftPXMPyridoxal kinase2.7.1.350.450
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.450
2cchATPCyclin-dependent kinase 22.7.11.220.450
2e8sSAHDiphthine synthase/0.450
2ed3SAHDiphthine synthase/0.450
2g8aUMPThymidylate synthase/0.450
2pcaSAHDiphthine synthase/0.450
2uxoTACHTH-type transcriptional regulator TtgR/0.450
2yyeAPCSelenide, water dikinase2.7.9.30.450
3a3gDLZLumazine protein/0.450
3elcF012-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.450
3gh8FMNIodotyrosine deiodinase 11.21.1.10.450
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
3i25MV7Beta-secretase 13.4.23.460.450
3kemIPE4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.450
3keqNADRedox-sensing transcriptional repressor Rex/0.450
3pwm017Gag-Pol polyprotein3.4.23.160.450
3sl2ATPSensor histidine kinase WalK/0.450
3uawADNPurine nucleoside phosphorylase DeoD-type/0.450
3w8rACPUridine kinase/0.450
4b4vL34Bifunctional protein FolD/0.450
4ead0NPThymidine phosphorylase2.4.2.40.450
4eqwCOACoenzyme A disulfide reductase/0.450
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.450
4i13FOLDihydrofolate reductase1.5.1.30.450
4lhvGDPRas-related protein Rab-8A/0.450
4nmdFDABifunctional protein PutA/0.450
4ohwATPProtein clpf-1/0.450
4qaiFMNNADPH dehydrogenase/0.450
4x3lMTARNA 2'-O ribose methyltransferase/0.450
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.450
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.450
1a59COA2-methylcitrate synthase/0.449
1b2lNDCAlcohol dehydrogenase1.1.1.10.449
1c7oPPGHemolysin/0.449
1h60STRPentaerythritol tetranitrate reductase/0.449
1qiqACCIsopenicillin N synthase1.21.3.10.449
1xe55FEPlasmepsin-23.4.23.390.449
2e07SAHDiphthine synthase/0.449
2freFMNNAD(P)H-flavin oxidoreductase/0.449
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.449
2qfoA51Heat shock protein HSP 90-alpha/0.449
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.449
2qxxTTPdCTP deaminase3.5.4.130.449
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.449
2znq401Peroxisome proliferator-activated receptor delta/0.449
3apwDP0Alpha-1-acid glycoprotein 2/0.449
3bw3FMNPutative 2-nitropropane dioxygenase/0.449
3clsFADElectron transfer flavoprotein subunit alpha/0.449
3eksCY9Actin-5C/0.449
3gkaFMNN-ethylmaleimide reductase/0.449
3jv7NADSecondary alcohol dehydrogenase/0.449
3k5fAYHBeta-secretase 13.4.23.460.449
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3oqfS51Renin3.4.23.150.449
3qaiXNNKetohexokinase/0.449
3qgf46FGenome polyprotein2.7.7.480.449
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.449
3rqhB6PADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.449
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.449
3v0p4GWHisto-blood group ABO system transferase/0.449
4dtbGMPAPH(2'')-Id/0.449
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.449
4pk4ADPUnconventional myosin-VI/0.449
4tm4FDAKtzI/0.449
5cc9DDFDihydrofolate reductase1.5.1.30.449
1g54FFBCarbonic anhydrase 24.2.1.10.448
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.448
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.448
1ma0NADAlcohol dehydrogenase class-31.1.1.10.448
1mj9COAHistone acetyltransferase ESA1/0.448
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.448
1w4lGL8Acetylcholinesterase3.1.1.70.448
1xjjDGTVitamin B12-dependent ribonucleotide reductase/0.448
2dvlFADAcyl-CoA dehydrogenase/0.448
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.448
2huvSAHDiphthine synthase/0.448
2huxSAHDiphthine synthase/0.448
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.448
2o2yTCLEnoyl-ACP reductase/0.448
2ofiADK3-methyladenine DNA glycosylase I/0.448
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.448
2ql6ADPNicotinamide riboside kinase 1/0.448
2qw034Z4-chlorobenzoyl CoA ligase/0.448
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.448
2vetUMPThymidylate synthase/0.448
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.448
2z54AB1Gag-Pol polyprotein3.4.23.160.448
3ai3NDPNADPH-sorbose reductase/0.448
3isjA8DPantothenate synthetase6.3.2.10.448
3mjrAC2Deoxycytidine kinase2.7.1.740.448
3mvm39PMitogen-activated protein kinase 14/0.448
3to3ATPPetrobactin biosynthesis protein AsbB/0.448
4b1uLABActin, alpha skeletal muscle/0.448
4b4w9L9Bifunctional protein FolD/0.448
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.448
4frkDWDBeta-secretase 13.4.23.460.448
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.448
4yaiNAIC alpha-dehydrogenase/0.448
1eveE20Acetylcholinesterase3.1.1.70.447
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.447
1pd9CO4Dihydrofolate reductase1.5.1.30.447
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.447
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.447
1vikBAYGag-Pol polyprotein/0.447
1w51L01Beta-secretase 13.4.23.460.447
1wuaAP8Actin, alpha skeletal muscle/0.447
2c27ACOMycothiol acetyltransferase2.3.1.1890.447
2dhfDZFDihydrofolate reductase1.5.1.30.447
2el3SAHDiphthine synthase/0.447
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.447
2g94ZPQBeta-secretase 13.4.23.460.447
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.447
2qbmCAMCamphor 5-monooxygenase1.14.15.10.447
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2yj4ATPCopper-transporting ATPase/0.447
3b1dPLSBetaC-S lyase/0.447
3csdEMOPutative ketoacyl reductase1.3.10.447
3hlwCE3Beta-lactamase/0.447
3p62FMNPentaerythritol tetranitrate reductase/0.447
3phjDHKShikimate dehydrogenase (NADP(+))/0.447
3qe2FMNNADPH--cytochrome P450 reductase/0.447
3qlrNDPDihydrofolate reductase1.5.1.30.447
3zgl10E4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.447
3zhbNAPPutative dehydrogenase/0.447
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.447
4a6nFADTetX family tetracycline inactivation enzyme/0.447
4dus0MPBeta-secretase 13.4.23.460.447
4fm80UQBeta-secretase 13.4.23.460.447
4iqqUMPThymidylate synthase/0.447
4kgkGTPUncharacterized protein/0.447
4n8iCOAPutative 4-hydroxybutyrate coenzyme A transferase/0.447
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.447
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.447
4rvnCOAPhenylacetate-coenzyme A ligase/0.447
4tm0FADKtzI/0.447
4u0mATPCyclic GMP-AMP synthase/0.447
4zgsNADPutative D-lactate dehydrogenase/0.447
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.447
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.447
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.447
5hg0SAMPantothenate synthetase/0.447
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.446
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.446
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.446
1kh3ANPArgininosuccinate synthase/0.446
1mvtDTMDihydrofolate reductase1.5.1.30.446
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.446
1ra3MTXDihydrofolate reductase1.5.1.30.446
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.446
1v453DGPurine nucleoside phosphorylase2.4.2.10.446
1z7yAA5Cysteine synthase 12.5.1.470.446
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.446
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.446
2dv3SAHDiphthine synthase/0.446
2hm1LIQBeta-secretase 13.4.23.460.446
2hsaFMN12-oxophytodienoate reductase 31.3.1.420.446
2jgsBTNAvidin/0.446
2pcgSAHDiphthine synthase/0.446
2q9fC3SCholesterol 24-hydroxylase/0.446
2rhgIGPTryptophan synthase alpha chain/0.446
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.446
3c27DKKProthrombin3.4.21.50.446
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3e5hGNPRas-related protein Rab-28/0.446
3ggoNAIPrephenate dehydrogenase/0.446
3gobHXXDdmC/0.446
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.446
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.446
3qlsNDPDihydrofolate reductase1.5.1.30.446
3t7p7SPEndothiapepsin3.4.23.220.446
4bfuZVUPantothenate kinase2.7.1.330.446
4eb5PLPCysteine desulfurase IscS 2/0.446
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.446
4ey6GNTAcetylcholinesterase3.1.1.70.446
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.446
4fhd0TTSpore photoproduct lyase/0.446
4i1iNADMalate dehydrogenase/0.446
4isk1JYThymidylate synthase/0.446
1c0lFADD-amino-acid oxidase1.4.3.30.445
1jzqILAIsoleucine--tRNA ligase6.1.1.50.445
1rszDIHPurine nucleoside phosphorylase2.4.2.10.445
1u0yPA7Endoplasmin/0.445
1w5sADPORC1-type DNA replication protein 2/0.445
2ab8MTPAdenosine kinase2.7.1.200.445
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.445
2b7aIZATyrosine-protein kinase JAK2/0.445
2dsgSAHDiphthine synthase/0.445
2erzHFScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2g20L1ARenin3.4.23.150.445
2ntrL00Beta-secretase 13.4.23.460.445
2pcmSAHDiphthine synthase/0.445
2rc4ACOHistone acetyltransferase KAT6A/0.445
2ydxSTLMethionine adenosyltransferase 2 subunit beta/0.445
3fp0FP015-O-acetyltransferase/0.445
3gwdFADCyclohexanone monooxygenase/0.445
3own3OXRenin3.4.23.150.445
3pl8FADPyranose 2-oxidase/0.445
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.445
3w8eNAD3-hydroxybutyrate dehydrogenase/0.445
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.445
4dt9GMPAPH(2'')-Id/0.445
4e32DWNMethyltransferase/0.445
4eh60ONMitogen-activated protein kinase 14/0.445
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.445
4f9gC2EStimulator of interferon genes protein/0.445
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.445
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.445
4rh10TTSpore photoproduct lyase/0.445
4tm1FDAKtzI/0.445
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
4yvkSFGtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.445
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.445
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.445
1ia1NDPDihydrofolate reductase1.5.1.30.444
1je1GMPPurine nucleoside phosphorylase/0.444
1l0oADPAnti-sigma F factor/0.444
1o97FADElectron transfer flavoprotein subunit alpha/0.444
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1rfvADPPyridoxal kinase2.7.1.350.444
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.444
1xz85GPBifunctional protein PyrR2.4.2.90.444
2e15SAHDiphthine synthase/0.444
2ft9CHDFatty acid-binding protein 2, liver/0.444
2vkvTDCTetracycline repressor protein class D/0.444
2xf3J01Uncharacterized protein/0.444
2y3pSM8DNA gyrase subunit A/0.444
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.444
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3a6qFMNFMN-binding protein/0.444
3d3wNAPL-xylulose reductase1.1.1.100.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.444
3ivgFG5Pantothenate synthetase6.3.2.10.444
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.444
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
3lxiCAMCytochrome P450/0.444
3nmpPYVAbscisic acid receptor PYL2/0.444
3nsh957Beta-secretase 13.4.23.460.444
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.444
3r9uFADThioredoxin reductase/0.444
3t3q9PLCytochrome P450 2A61.14.130.444
3uayADNPurine nucleoside phosphorylase DeoD-type/0.444
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.444
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.444
4eqsCOACoenzyme A disulfide reductase/0.444
4i0i957Beta-secretase 13.4.23.460.444
4iraFAD4-hydroxyphenylacetate 3-monooxygenase/0.444
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.444
4k6fNAPPutative Acetoacetyl-CoA reductase/0.444
4opgFDAConserved Archaeal protein/0.444
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.444
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.443
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.443
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
1n06ADPRiboflavin kinase2.7.1.260.443
1n83CLRNuclear receptor ROR-alpha/0.443
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.443
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1rd7FOLDihydrofolate reductase1.5.1.30.443
1tl7FOKAdenylate cyclase type 2/0.443
1tl7FOKAdenylate cyclase type 5/0.443
1u0hFOKAdenylate cyclase type 2/0.443
1u0hFOKAdenylate cyclase type 5/0.443
1vhzAPRADP compounds hydrolase NudE3.6.10.443
1w5tADPORC1-type DNA replication protein 2/0.443
1wur8DGGTP cyclohydrolase 1/0.443
1x1cSAHC-20 methyltransferase/0.443
1yzqGNPRas-related protein Rab-6A/0.443
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.443
2ad5ADPCTP synthase/0.443
2eeqSAHDiphthine synthase/0.443
2ejjSAHDiphthine synthase/0.443
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.443
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.443
2ojg19AMitogen-activated protein kinase 12.7.11.240.443
2ou2ACOHistone acetyltransferase KAT5/0.443
2pncCLUPrimary amine oxidase, liver isozyme/0.443
2vigCOSShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.443
2xfyACXBeta-amylase3.2.1.20.443
2y0mACOHistone acetyltransferase KAT8/0.443
2z6iFMN2-nitropropane dioxygenase/0.443
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.443
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.443
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.443
3c16FOKAdenylate cyclase type 2/0.443
3c16FOKAdenylate cyclase type 5/0.443
3d84NDPDihydrofolate reductase1.5.1.30.443
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fpjSAMUncharacterized protein/0.443
3iphG11Mitogen-activated protein kinase 14/0.443
3jziJZLBiotin carboxylase6.3.4.140.443
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.443
3mj4URMUDP-galactopyranose mutase/0.443
3oetNADErythronate-4-phosphate dehydrogenase/0.443
3oht1N1Mitogen-activated protein kinase/0.443
3to6LYS_CMCHistone acetyltransferase ESA1/0.443
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.443
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.443
3ziuLSSLeucyl-tRNA synthetase/0.443
4a6rTA8Probable aminotransferase/0.443
4a7b3W5Collagenase 33.4.240.443
4avlTMPPolymerase acidic protein/0.443
4c58824Cyclin-G-associated kinase2.7.11.10.443
4ck2NVUIntegrase/0.443
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.443
4f5yC2EStimulator of interferon genes protein/0.443
4gcmNAPThioredoxin reductase1.8.1.90.443
4id9NADPutative UDP-glucose 4-epimerase/0.443
4imfSI3N-acetylneuraminate lyase/0.443
4lxb7R9Prothrombin3.4.21.50.443
4mb2ATPUncharacterized protein/0.443
4nv14TGFormyl transferase/0.443
4xfjANPArgininosuccinate synthase/0.443
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.443
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.443
5k5zANPUncharacterized protein/0.443
1dncFADGlutathione reductase, mitochondrial1.8.1.70.442
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.442
1rdwLARActin, alpha skeletal muscle/0.442
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.442
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.442
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1xe65FPPlasmepsin-23.4.23.390.442
1xl5190Gag-Pol polyprotein3.4.23.160.442
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2briANPUridylate kinase2.7.4.220.442
2bu9HFVIsopenicillin N synthase1.21.3.10.442
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.442
2e17SAHDiphthine synthase/0.442
2eh4SAHDiphthine synthase/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2fznFADBifunctional protein PutA1.5.5.20.442
2gjlFMNNitronate monooxygenase1.13.12.160.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.442
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.442
2os3BB2Peptide deformylase/0.442
2pckSAHDiphthine synthase/0.442
2r9xWH6Beta-lactamase3.5.2.60.442
2xaaNADSecondary alcohol dehydrogenase/0.442
3cvuFADRE11660p/0.442
3d91REMRenin3.4.23.150.442
3daaPDDD-alanine aminotransferase2.6.1.210.442
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3gqvNAPEnoyl reductase LovC10.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3r83Z14Cyclin-dependent kinase 22.7.11.220.442
3t82SG4Carbonic anhydrase 24.2.1.10.442
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
3vdqNAD3-hydroxybutyrate dehydrogenase/0.442
3wwmADP[LysW]-aminoadipate kinase/0.442
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4cghLOZIntegrase/0.442
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.442
4db1ANPMyosin-7/0.442
4e2dFMNDehydrogenase/0.442
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.442
4eyb0WOMetallo-beta-lactamase type 2/0.442
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.442
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.442
4hj6FMNLOV protein/0.442
4iji99TGlutathione S-transferase-like protein YibF/0.442
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.442
4kc1WS1Histo-blood group ABO system transferase/0.442
4kouC04Uncharacterized protein/0.442
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.442
4mlp2CXCryptochrome-2/0.442
4r81FMNPredicted NADH dehydrogenase/0.442
4yqfGDPSeptin-9/0.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
5eccNAPDehydrofolate reductase type I/0.442
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.442
1a9cGTPGTP cyclohydrolase 13.5.4.160.441
1cnfFADNitrate reductase [NADH]1.7.1.10.441
1dr3HBIDihydrofolate reductase1.5.1.30.441
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.441
1lbcCYZGlutamate receptor 2/0.441
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1m76CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1o2g696Prothrombin3.4.21.50.441
1pt5ACOFormyl-CoA:oxalate CoA-transferase/0.441
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.441
1snfUMPDeoxyuridine 5'-triphosphate nucleotidohydrolase3.6.1.230.441
1tj0FADBifunctional protein PutA1.5.5.20.441
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.90.441
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.441
2daaDCSD-alanine aminotransferase2.6.1.210.441
2e8hSAHDiphthine synthase/0.441
2e8rSAHDiphthine synthase/0.441
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.441
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.441
2nniMTKCytochrome P450 2C8/0.441
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2oo7AP5Adenylate kinase/0.441
2p2xSAHDiphthine synthase/0.441
2p4sDIHAGAP005945-PA/0.441
2pciSAHDiphthine synthase/0.441
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.441
2vttLZDCyclin-dependent kinase 22.7.11.220.441
2wzwNDPNitroreductase NfnB/0.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.441
3bc3OPTCathepsin L13.4.22.150.441
3gvhNADMalate dehydrogenase/0.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3mauPLRPutative sphingosine-1-phosphate lyase/0.441
3nk7SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase/0.441
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.441
3rh7FMNUncharacterized protein/0.441
3t3r9PLCytochrome P450 2A61.14.130.441
3t84SG6Carbonic anhydrase 24.2.1.10.441
3toxNAPPutative oxidoreductase/0.441
4baoMVFProthrombin3.4.21.50.441
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.441
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.441
4c72TLG3-oxoacyl-ACP synthase/0.441
4hs4FMNChromate reductase/0.441
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.441
4koyCSCUncharacterized protein/0.441
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.441
4o671SYCyclic GMP-AMP synthase/0.441
1aobDDUThymidylate synthase/0.440
1cjuFOKAdenylate cyclase type 2/0.440
1cjuFOKAdenylate cyclase type 5/0.440
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.440
1h74ADPHomoserine kinase2.7.1.390.440
1j21ATPArgininosuccinate synthase/0.440
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.440
1me6IVSPlasmepsin-23.4.23.390.440
1oo5FMNOxygen-insensitive NAD(P)H nitroreductase/0.440
1ozpACOMycothiol acetyltransferase2.3.1.1890.440
1pg3PRXAcetyl-coenzyme A synthetase/0.440
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.440
1s7nCOAAcetyl transferase/0.440
1tduDURThymidylate synthase/0.440
1tojHCIAspartate aminotransferase2.6.1.10.440
1yqdNAPSinapyl alcohol dehydrogenase/0.440
2g1y5IGRenin3.4.23.150.440
2g21L1BRenin3.4.23.150.440
2givACOHistone acetyltransferase KAT8/0.440
2omeNADC-terminal-binding protein 2/0.440
2ph835ABeta-secretase 13.4.23.460.440
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2vwqNAPGlucose 1-dehydrogenase/0.440
2xfiXFIBeta-secretase 13.4.23.460.440
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.440
2ylzFADPhenylacetone monooxygenase1.14.13.920.440
2z6rSAHDiphthine synthase/0.440
3ctyFADProbable thioredoxin reductase/0.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3elm24FCollagenase 33.4.240.440
3f1kNAPUncharacterized oxidoreductase YciK10.440
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3jzdNADMaleylacetate reductase/0.440
3lpjZ75Beta-secretase 13.4.23.460.440
3otwCOAPhosphopantetheine adenylyltransferase/0.440
3q8uADPNucleoside diphosphate kinase/0.440
3qfcFADNADPH--cytochrome P450 reductase/0.440
3qwbNDPProbable quinone oxidoreductase1.6.5.50.440
3rpeFADPutative modulator of drug activity/0.440
3vydVYDRenin3.4.23.150.440
3zuyTCHTransporter/0.440
4ejmNAPPutative zinc-binding dehydrogenase/0.440
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4giu636Anthranilate phosphoribosyltransferase/0.440
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4iva1J5Tyrosine-protein kinase JAK2/0.440
4k9oTPPBenzoylformate decarboxylase4.1.1.70.440
4ktkKTKCytochrome P450/0.440
4qzuRTLRetinol-binding protein 2/0.440
4xbjIN5Alanine racemase, biosynthetic/0.440
5a1tNAIL-lactate dehydrogenase/0.440
5aqzSGVHeat shock 70 kDa protein 1A/0.440
4xnw2IDP2Y purinoceptor 1/0.440