Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1x96NAPAldose reductase1.1.1.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1x96NAPAldose reductase1.1.1.211.000
1x98NAPAldose reductase1.1.1.210.798
2j8tNAPAldose reductase1.1.1.210.744
2iq0NAPAldose reductase1.1.1.210.724
1az2NAPAldose reductase1.1.1.210.697
2acqNAPAldose reductase1.1.1.210.678
2acsNAPAldose reductase1.1.1.210.659
1z8aNAPAldose reductase1.1.1.210.647
3q65NAPAldose reductase1.1.1.210.610
3v36NAPAldose reductase1.1.1.210.610
1ah4NAPAldose reductase1.1.1.210.607
3q67NAPAldose reductase1.1.1.210.597
2pfhNDPAldose reductase1.1.1.210.584
2acuNAPAldose reductase1.1.1.210.577
2pf8NDPAldose reductase1.1.1.210.553
3h7rNAPAldo-keto reductase family 4 member C8/0.536
2pevNDPAldose reductase1.1.1.210.533
3o3rNAPAldose reductase-related protein 11.1.1.210.531
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.521
3qkzNAPAldose reductase-related protein 11.1.1.210.519
1c9wNAPAldose reductase-related protein 2/0.515
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.512
1adsNAPAldose reductase1.1.1.210.505
2hejNDPAldo-keto reductase family 1 member C211.1.10.505
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.500
4g5dNDPProstaglandin F synthase1.1.1.1880.498
4pmjNAPPutative oxidoreductase/0.488
1r38NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.483
4xzmNAPAldo-keto reductase family 1 member B101.1.10.483
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.478
1ef3NAPAldose reductase1.1.1.210.472
1mi3NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.470
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.470
1zgdNAPChalcone reductase/0.464
4jtqNAPAldo-keto reductase family 1 member C2/0.464
2hdjNDPAldo-keto reductase family 1 member C2/0.462
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.460
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.458
1s1rNAPAldo-keto reductase family 1 member C3/0.455
2vdgNDPAldose reductase1.1.1.210.452
4xo7NAPAldo-keto reductase family 1 member C2/0.452
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
2p5nNDPAldo-keto reductase family 1 member C211.1.10.444
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.440
4xznNAPAldo-keto reductase family 1 member B101.1.10.440