sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 1.000 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.730 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.610 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.458 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.449 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.440 |