sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 1.000 | |
| 1wtg | 3BP | Coagulation factor VII | 3.4.21.21 | 0.667 | |
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 | 0.588 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.582 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.579 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.572 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.561 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.560 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.559 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.552 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.551 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.550 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.548 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.543 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.541 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.540 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.538 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.537 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.535 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.533 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.532 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.531 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.531 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.530 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.530 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.530 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.529 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.529 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.529 | |
| 1wv7 | 5PI | Coagulation factor VII | 3.4.21.21 | 0.528 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.528 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.527 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.527 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.526 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.525 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.524 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.523 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.521 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.520 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.519 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.519 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.519 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.518 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.518 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.518 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.517 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.517 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.517 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.517 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.517 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.517 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.517 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.516 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.515 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.515 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.513 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.513 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.512 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.512 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.509 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.508 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.508 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.508 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.507 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.507 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.507 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.506 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.506 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.505 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.504 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.503 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.503 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.503 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.502 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.502 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.502 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.501 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.501 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.501 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.501 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.501 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.500 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.500 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.498 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.497 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.497 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.497 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.496 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.495 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.495 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.493 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.493 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.493 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.492 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.491 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.491 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.490 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.490 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.490 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.490 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.490 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.489 | |
| 1w13 | SM1 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.489 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.489 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.488 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.488 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.488 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.488 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.487 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.487 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.487 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.486 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.486 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.486 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.486 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.485 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.485 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.485 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.485 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.484 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.484 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.483 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.483 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.483 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.483 | |
| 3v49 | PK0 | Androgen receptor | / | 0.483 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.483 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.483 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.482 | |
| 4loc | BTN | Pyruvate carboxylase | / | 0.482 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.481 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.481 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.481 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.480 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.479 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.479 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.479 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.479 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.479 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.479 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.478 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.478 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.478 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.478 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.477 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.477 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.477 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.476 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.476 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.476 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.475 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.475 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.474 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.474 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.474 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.474 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.474 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.473 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.473 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.473 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.473 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.473 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.473 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.473 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.473 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.472 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.472 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.472 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.472 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.472 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.472 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.472 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.472 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.472 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.471 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.471 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.471 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.471 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.471 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.471 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.471 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.470 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.470 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.470 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.470 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.470 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.470 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.470 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.469 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.469 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.469 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.469 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.469 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.469 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.469 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.469 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.469 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.469 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.468 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.468 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.468 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3eku | CY9 | Actin-5C | / | 0.468 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.468 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.468 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.467 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.467 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.467 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.467 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.467 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.467 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.467 | |
| 4el0 | D1K | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.467 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4ig6 | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.467 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.466 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.466 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.466 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.466 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.466 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.466 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.466 | |
| 3tdj | 3TJ | Glutamate receptor 2 | / | 0.466 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.466 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.466 | |
| 5a3b | APR | SIR2 family protein | / | 0.466 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.466 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.465 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.465 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.465 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.465 | |
| 1z45 | UPG | Bifunctional protein GAL10 | 5.1.3.2 | 0.465 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.465 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.464 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.464 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.464 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.464 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.464 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.464 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.464 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.464 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.464 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.463 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2iiq | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.463 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.463 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.463 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.463 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.463 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.463 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.462 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2ohv | NHL | Glutamate racemase | / | 0.462 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.462 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.462 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.462 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.462 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.462 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.462 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.461 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.461 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.461 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.461 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.461 | |
| 2x3j | ATP | AcsD | / | 0.461 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.461 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.461 | |
| 3lcv | SAM | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.461 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.461 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.461 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.460 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 2buf | ADP | Acetylglutamate kinase | / | 0.460 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.460 | |
| 2emr | SAH | Diphthine synthase | / | 0.460 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3bhr | THG | Thymidylate synthase | / | 0.460 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.460 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.460 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.460 | |
| 4yqf | GDP | Septin-9 | / | 0.460 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.460 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.459 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2e8q | SAH | Diphthine synthase | / | 0.459 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.459 | |
| 2xby | 63C | Coagulation factor X | 3.4.21.6 | 0.459 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.459 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.459 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.459 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.459 | |
| 4kwh | NAP | Reductase homolog | / | 0.459 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.459 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.459 | |
| 1cgz | STL | Chalcone synthase 2 | 2.3.1.74 | 0.458 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.458 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.458 | |
| 2ejz | SAH | Diphthine synthase | / | 0.458 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.458 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.458 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.458 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.458 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3iaa | TYD | CalG2 | / | 0.458 | |
| 3mel | TPP | Thiamin pyrophosphokinase family protein | / | 0.458 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.458 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.458 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.458 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.458 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.458 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.457 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.457 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.457 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.457 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.457 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3nk7 | SAM | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase | / | 0.457 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.457 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.457 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.457 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.457 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.457 | |
| 4xr9 | NAD | CalS8 | / | 0.457 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.456 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.456 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.456 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.456 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.456 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.456 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.456 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.456 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.456 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.456 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.456 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.456 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.456 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.456 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.456 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.456 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.455 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.455 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.455 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.455 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.455 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.455 | |
| 3a6q | FMN | FMN-binding protein | / | 0.455 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.455 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.455 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.455 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.455 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.455 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.455 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.455 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.455 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.455 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.454 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.454 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.454 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.454 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.454 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.454 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.454 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.454 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.454 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.454 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.454 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.454 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.454 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.454 | |
| 3e39 | FMN | Nitroreductase | / | 0.454 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.454 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.454 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.454 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.454 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.454 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.454 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.454 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.453 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.453 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.453 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.453 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.453 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.453 | |
| 2r3a | SAM | Histone-lysine N-methyltransferase SUV39H2 | 2.1.1.43 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.453 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.453 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.453 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.453 | |
| 4bmp | FMN | Protein NrdI | / | 0.453 | |
| 4e9a | QAP | Peptide deformylase | / | 0.453 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.453 | |
| 4l4x | NDP | AmphI | / | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.452 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.452 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.452 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.452 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.452 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.452 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.452 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.452 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.452 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3mje | NDP | AmphB | / | 0.452 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.452 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.452 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.452 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.452 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.451 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.451 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.451 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.451 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.451 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.451 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.451 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.451 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2dxw | SAH | Diphthine synthase | / | 0.451 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.451 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.451 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.451 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.451 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.451 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.451 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.451 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.450 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.450 | |
| 2nr4 | FMN | Conserved protein | / | 0.450 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.450 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.450 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.450 | |
| 3e51 | N35 | Genome polyprotein | 2.7.7.48 | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.450 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.450 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.450 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.450 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.450 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.450 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.450 | |
| 1c7o | PPG | Hemolysin | / | 0.449 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.449 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.449 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.449 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.449 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.449 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.449 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.449 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.449 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.449 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4qec | NAP | ElxO | / | 0.449 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.449 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.449 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.448 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.448 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.448 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.448 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.448 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.448 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.448 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.448 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.448 | |
| 4u7w | NDP | MxaA | / | 0.448 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.447 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.447 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.447 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.447 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.447 | |
| 2ejk | SAH | Diphthine synthase | / | 0.447 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.447 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.447 | |
| 2owu | SAH | Diphthine synthase | / | 0.447 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.447 | |
| 2pcm | SAH | Diphthine synthase | / | 0.447 | |
| 2xlu | NA7 | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.447 | |
| 3kmt | SAH | Histone H3K27 methylase | / | 0.447 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.447 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.447 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.447 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.447 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.447 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.447 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.447 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.447 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.446 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.446 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.446 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.446 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.446 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.446 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.446 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.446 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.446 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.446 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.446 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.446 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.446 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.446 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.445 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.445 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.445 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.445 | |
| 1ytm | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.445 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.445 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.445 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.445 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.445 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.445 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.445 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.445 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.444 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.444 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.444 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.444 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.444 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2z6r | SAH | Diphthine synthase | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.444 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.444 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.444 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.444 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.444 | |
| 4qed | NAP | ElxO | / | 0.444 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.444 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.444 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.444 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.443 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.443 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.443 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.443 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.443 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.443 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.443 | |
| 2e15 | SAH | Diphthine synthase | / | 0.443 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2p6i | SAH | Diphthine synthase | / | 0.443 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3a20 | FMN | FMN-binding protein | / | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.443 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.443 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.443 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.443 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.443 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.443 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.443 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.443 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.443 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.443 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.443 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.443 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.443 | |
| 5efw | FMN | NPH1-1 | / | 0.443 | |
| 5fsy | AR6 | Uncharacterized protein | / | 0.443 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.442 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.442 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.442 | |
| 1tys | DHF | Thymidylate synthase | / | 0.442 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.442 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.442 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.442 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.442 | |
| 2ehl | SAH | Diphthine synthase | / | 0.442 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.442 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.442 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.442 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.442 | |
| 3b3f | SAH | Histone-arginine methyltransferase CARM1 | / | 0.442 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.442 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.442 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 4z38 | FMN | MlnA | / | 0.442 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.442 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.441 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.441 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.441 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.441 | |
| 1w7i | ADP | Unconventional myosin-Va | / | 0.441 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2dxv | SAH | Diphthine synthase | / | 0.441 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.441 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.441 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.441 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.441 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.441 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.441 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.441 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.441 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.441 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 4gap | NAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.441 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.441 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.441 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.440 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.440 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.440 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.440 | |
| 2e07 | SAH | Diphthine synthase | / | 0.440 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2r7p | ANP | Non-structural protein 2 | 3.6.4 | 0.440 | |
| 2vet | UMP | Thymidylate synthase | / | 0.440 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.440 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.440 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.440 | |
| 3qvs | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.440 | |
| 3ru0 | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.440 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.440 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.440 | |
| 3vc2 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.440 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.440 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.440 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4jxr | ACO | Acetyltransferase | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 |