sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 1.000 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.593 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.475 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.462 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.457 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.456 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.452 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.452 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 3r3d | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.447 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.447 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.440 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.440 |