sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1w2x | RCP | Acetyl-CoA carboxylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 1.000 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.586 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.562 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.552 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.487 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.473 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.470 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.461 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.455 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.451 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.448 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.445 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.444 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.442 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.442 |