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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1vp5NAPOxidoreductase, aldo/keto reductase family

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1vp5NAPOxidoreductase, aldo/keto reductase family/1.000
1r38NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.483
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.478
1mi3NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.474
4g5dNDPProstaglandin F synthase1.1.1.1880.467
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.464
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.462
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.461
1ye6NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.456
4pmjNAPPutative oxidoreductase/0.456
1sm9NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.455
3q65NAPAldose reductase1.1.1.210.453
1az2NAPAldose reductase1.1.1.210.449
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.447
2acqNAPAldose reductase1.1.1.210.446
2iq0NAPAldose reductase1.1.1.210.446
2pf8NDPAldose reductase1.1.1.210.440