Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1v35NAIEnoyl-ACP reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1v35NAIEnoyl-ACP reductase/1.000
1vrwNAIEnoyl-ACP reductase/0.595
4o1mNADEnoyl-acyl carrier reductase/0.572
2nq8ZIDEnoyl-ACP reductase/0.546
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.507
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.474
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.472
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.470
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446