sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uom | PTI | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uom | PTI | Estrogen receptor | / | 1.000 | |
| 1yin | CM3 | Estrogen receptor | / | 0.638 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.611 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.610 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.595 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.594 | |
| 1err | RAL | Estrogen receptor | / | 0.579 | |
| 1nde | MON | Estrogen receptor beta | / | 0.529 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.529 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.528 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.517 | |
| 2jfa | RAL | Estrogen receptor | / | 0.506 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.501 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.494 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.490 | |
| 2pog | WST | Estrogen receptor | / | 0.489 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.481 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.473 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.469 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.464 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.460 | |
| 3aba | FLI | Cytochrome P450 | / | 0.459 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.457 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.456 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.455 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.455 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.454 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.453 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.450 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.448 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.448 | |
| 2qjy | SMA | Cytochrome b | / | 0.445 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.444 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.442 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.440 |