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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ungALHCyclin-dependent-like kinase 52.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ungALHCyclin-dependent-like kinase 52.7.11.11.000
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.530
3rmf20ZCyclin-dependent kinase 22.7.11.220.529
4bcpT3CCyclin-dependent kinase 22.7.11.220.529
3r7iX9ICyclin-dependent kinase 22.7.11.220.527
2f2cAP9Cyclin-dependent kinase 62.7.11.220.523
1e9hINRCyclin-dependent kinase 22.7.11.220.521
1oi9N20Cyclin-dependent kinase 22.7.11.220.521
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.521
2i40BLZCyclin-dependent kinase 22.7.11.220.519
3qxoX65Cyclin-dependent kinase 22.7.11.220.518
4qmzB49Serine/threonine-protein kinase 242.7.11.10.518
3rm618ZCyclin-dependent kinase 22.7.11.220.517
3rni21ZCyclin-dependent kinase 22.7.11.220.516
3my5RFZCyclin-dependent kinase 22.7.11.220.515
3ezrEZRCyclin-dependent kinase 22.7.11.220.514
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.511
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.509
3qu0X40Cyclin-dependent kinase 22.7.11.220.507
3s2pPMUCyclin-dependent kinase 22.7.11.220.507
3tnwF18Cyclin-dependent kinase 22.7.11.220.507
1oiyN41Cyclin-dependent kinase 22.7.11.220.506
2bhhRYUCyclin-dependent kinase 22.7.11.220.506
3pj8404Cyclin-dependent kinase 22.7.11.220.506
5cvhADPCasein kinase II subunit alpha2.7.11.10.506
1ke9LS5Cyclin-dependent kinase 22.7.11.220.505
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.505
1unlRRCCyclin-dependent-like kinase 52.7.11.10.504
2iw84SPCyclin-dependent kinase 22.7.11.220.504
3r7eX88Cyclin-dependent kinase 22.7.11.220.503
3r8zZ63Cyclin-dependent kinase 22.7.11.220.502
1aq1STUCyclin-dependent kinase 22.7.11.220.501
2fvdLIACyclin-dependent kinase 22.7.11.220.501
4bcnT9NCyclin-dependent kinase 22.7.11.220.501
4eok4SPCyclin-dependent kinase 22.7.11.220.501
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.500
2w05FRTCyclin-dependent kinase 22.7.11.220.500
2wxvWXVCyclin-dependent kinase 22.7.11.220.500
3rjc06ZCyclin-dependent kinase 22.7.11.220.500
2btsU32Cyclin-dependent kinase 22.7.11.220.499
3qziX72Cyclin-dependent kinase 22.7.11.220.499
3s1h56ZCyclin-dependent kinase 22.7.11.220.499
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.499
1fvt106Cyclin-dependent kinase 22.7.11.220.498
3ddqRRCCyclin-dependent kinase 22.7.11.220.498
3dogNNNCyclin-dependent kinase 22.7.11.220.498
3r7yZ04Cyclin-dependent kinase 22.7.11.220.498
3sqq99ZCyclin-dependent kinase 22.7.11.220.498
1gih1PUCyclin-dependent kinase 22.7.11.220.497
1v1k3FPCyclin-dependent kinase 22.7.11.220.497
3be9P04Casein kinase II subunit alpha2.7.11.10.497
3rpv26ZCyclin-dependent kinase 22.7.11.220.497
3rm719ZCyclin-dependent kinase 22.7.11.220.496
4fkr45KCyclin-dependent kinase 22.7.11.220.495
3qxpX64Cyclin-dependent kinase 22.7.11.220.494
3r1sX73Cyclin-dependent kinase 22.7.11.220.494
1h1r6CPCyclin-dependent kinase 22.7.11.220.493
2btrU73Cyclin-dependent kinase 22.7.11.220.493
2iw94SPCyclin-dependent kinase 22.7.11.220.493
3r9dX6BCyclin-dependent kinase 22.7.11.220.493
3rak03ZCyclin-dependent kinase 22.7.11.220.493
3ral04ZCyclin-dependent kinase 22.7.11.220.493
4bcoT6QCyclin-dependent kinase 22.7.11.220.493
4cfnJYMCyclin-dependent kinase 22.7.11.220.493
2wihP48Cyclin-dependent kinase 22.7.11.220.492
4erwSTUCyclin-dependent kinase 22.7.11.220.492
3lfnA27Cyclin-dependent kinase 22.7.11.220.491
3q9xEMOCasein kinase II subunit alpha2.7.11.10.491
3r8pZ46Cyclin-dependent kinase 22.7.11.220.491
4grb0XGCasein kinase II subunit alpha2.7.11.10.491
1oguST8Cyclin-dependent kinase 22.7.11.220.490
1oirHDYCyclin-dependent kinase 22.7.11.220.490
2vu3LZECyclin-dependent kinase 22.7.11.220.490
1pkdUCNCyclin-dependent kinase 22.7.11.220.489
3qtqX35Cyclin-dependent kinase 22.7.11.220.489
3rk708ZCyclin-dependent kinase 22.7.11.220.489
3rkb12ZCyclin-dependent kinase 22.7.11.220.489
1bwsNDPGDP-L-fucose synthase/0.488
3ddpRC8Cyclin-dependent kinase 22.7.11.220.488
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.488
3ql8X01Cyclin-dependent kinase 22.7.11.220.488
3qzhX69Cyclin-dependent kinase 22.7.11.220.488
4cd2FOLDihydrofolate reductase1.5.1.30.488
2w06FRVCyclin-dependent kinase 22.7.11.220.487
3axwTIDCasein kinase II subunit alpha2.7.11.10.487
3unj0BXCyclin-dependent kinase 22.7.11.220.487
3wblPDYCyclin-dependent kinase 22.7.11.220.487
4acm7YGCyclin-dependent kinase 22.7.11.220.487
4jqeANPCasein kinase II subunit alpha2.7.11.10.487
2b55D31Cyclin-dependent kinase 22.7.11.220.486
2izt23DCasein kinase I isoform gamma-32.7.11.10.486
2pvnP63Casein kinase II subunit alpha2.7.11.10.486
1di8DTQCyclin-dependent kinase 22.7.11.220.485
2wpa889Cyclin-dependent kinase 22.7.11.220.485
3le62BZCyclin-dependent kinase 22.7.11.220.485
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.485
2b52D42Cyclin-dependent kinase 22.7.11.220.484
2cchATPCyclin-dependent kinase 22.7.11.220.484
2duv371Cyclin-dependent kinase 22.7.11.220.484
3nga3NGCasein kinase II subunit alpha2.7.11.10.484
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.484
3rk909ZCyclin-dependent kinase 22.7.11.220.484
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.484
1ke6LS2Cyclin-dependent kinase 22.7.11.220.483
3lfqA28Cyclin-dependent kinase 22.7.11.220.483
4eor4SPCyclin-dependent kinase 22.7.11.220.483
2r3p3SCCyclin-dependent kinase 22.7.11.220.482
2x1nX1NCyclin-dependent kinase 22.7.11.220.482
4eomATPCyclin-dependent kinase 22.7.11.220.482
1unhIXMCyclin-dependent-like kinase 52.7.11.10.481
2c6tDT5Cyclin-dependent kinase 22.7.11.220.481
3rk507ZCyclin-dependent kinase 22.7.11.220.481
4ez30S0Cyclin-dependent kinase 22.7.11.220.481
4qmySTUSerine/threonine-protein kinase 242.7.11.10.481
3r1yX76Cyclin-dependent kinase 22.7.11.220.480
3roy22ZCyclin-dependent kinase 22.7.11.220.480
4ia3BIVVitamin D3 receptor A/0.480
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.479
3mb601ICasein kinase II subunit alpha2.7.11.10.479
4dgnLU2Casein kinase II subunit alpha2.7.11.10.479
4j97ACPFibroblast growth factor receptor 2/0.479
1vyw292Cyclin-dependent kinase 22.7.11.220.478
2a0cCK9Cyclin-dependent kinase 22.7.11.220.478
2uzeC95Cyclin-dependent kinase 22.7.11.220.478
3lfsA07Cyclin-dependent kinase 22.7.11.220.478
1r78FMDCyclin-dependent kinase 22.7.11.220.477
2uznC96Cyclin-dependent kinase 22.7.11.220.477
3bhtMFRCyclin-dependent kinase 22.7.11.220.477
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.477
3qtrX36Cyclin-dependent kinase 22.7.11.220.477
3qtzX42Cyclin-dependent kinase 22.7.11.220.477
3qwkX62Cyclin-dependent kinase 22.7.11.220.477
3r6xX84Cyclin-dependent kinase 22.7.11.220.477
3r8lZ30Cyclin-dependent kinase 22.7.11.220.477
4bb432WEphrin type-B receptor 42.7.10.10.477
4dgo0JWCasein kinase II subunit alpha2.7.11.10.477
1h1q2A6Cyclin-dependent kinase 22.7.11.220.476
3q9yTXQCasein kinase II subunit alpha2.7.11.10.476
3uli1N3Cyclin-dependent kinase 22.7.11.220.476
5a9sNAPPutative dehydrogenase/0.476
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.475
2x7gPVBSRSF protein kinase 22.7.11.10.475
3ezvEZVCyclin-dependent kinase 22.7.11.220.475
3qrtX14Cyclin-dependent kinase 22.7.11.220.475
3qzgX67Cyclin-dependent kinase 22.7.11.220.475
4fkv61KCyclin-dependent kinase 22.7.11.220.475
4fkw62KCyclin-dependent kinase 22.7.11.220.475
4gub0Y4Casein kinase II subunit alpha2.7.11.10.475
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.475
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.475
5e8wSTUTGF-beta receptor type-12.7.11.300.475
1p2a5BNCyclin-dependent kinase 22.7.11.220.474
3c4xATPRhodopsin kinase/0.474
3qqlX03Cyclin-dependent kinase 22.7.11.220.474
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4gk2L66Ephrin type-A receptor 32.7.10.10.474
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.474
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.474
1d2sDHTSex hormone-binding globulin/0.473
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.473
1jpaANPEphrin type-B receptor 22.7.10.10.473
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.473
2a4lRRCCyclin-dependent kinase 22.7.11.220.473
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
2pvlP55Casein kinase II subunit alpha2.7.11.10.473
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.473
2vttLZDCyclin-dependent kinase 22.7.11.220.473
4bcqTJFCyclin-dependent kinase 22.7.11.220.473
1w0xOLOCyclin-dependent kinase 22.7.11.220.472
1ykr628Cyclin-dependent kinase 22.7.11.220.472
2c4g514Cyclin-dependent kinase 22.7.11.220.472
2hcdBIVVitamin D3 receptor A/0.472
3r7vZ02Cyclin-dependent kinase 22.7.11.220.472
1pyePM1Cyclin-dependent kinase 22.7.11.220.471
3a4vNADNDP-sugar epimerase/0.471
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.471
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.471
4f700STCyclin-dependent kinase 82.7.11.220.471
4fx360KCyclin-dependent kinase 22.7.11.220.471
1pxmCK5Cyclin-dependent kinase 22.7.11.220.470
2bheBRYCyclin-dependent kinase 22.7.11.220.470
2c5nCK8Cyclin-dependent kinase 22.7.11.220.470
2vwz7X6Ephrin type-B receptor 42.7.10.10.470
3qqkX02Cyclin-dependent kinase 22.7.11.220.470
3sw719KCyclin-dependent kinase 22.7.11.220.470
3vt5YI2Vitamin D3 receptor/0.470
4ek816KCyclin-dependent kinase 22.7.11.220.470
4y8wSTRSteroid 21-hydroxylase/0.470
1fvv107Cyclin-dependent kinase 22.7.11.220.469
1gii1PUCyclin-dependent kinase 22.7.11.220.469
1oiuN76Cyclin-dependent kinase 22.7.11.220.469
2w1hL0FCyclin-dependent kinase 22.7.11.220.469
2wipP49Cyclin-dependent kinase 22.7.11.220.469
3hmm855TGF-beta receptor type-12.7.11.300.469
4bchT7ZCyclin-dependent kinase 92.7.11.220.469
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.469
4xwtU5PRibonuclease J/0.469
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.468
2uzdC85Cyclin-dependent kinase 22.7.11.220.468
2uzlC94Cyclin-dependent kinase 22.7.11.220.468
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.468
3r28XA0Cyclin-dependent kinase 22.7.11.220.468
3r7uX96Cyclin-dependent kinase 22.7.11.220.468
3r83Z14Cyclin-dependent kinase 22.7.11.220.468
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.468
1nvtNAPShikimate dehydrogenase (NADP(+))/0.467
1ppjANYCytochrome b/0.467
2bfyH1NAurora kinase B-A2.7.11.10.467
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.467
3r9hZ67Cyclin-dependent kinase 22.7.11.220.467
3s0o50ZCyclin-dependent kinase 22.7.11.220.467
4q71FADBifunctional protein PutA/0.467
1fm4DXCMajor pollen allergen Bet v 1-L/0.466
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.466
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.466
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.466
2jn3JN3Fatty acid-binding protein, liver/0.466
2qoqANPEphrin type-A receptor 32.7.10.10.466
2r64740Cyclin-dependent kinase 22.7.11.220.466
3p8zSAHGenome polyprotein2.1.1.560.466
4fkg4CKCyclin-dependent kinase 22.7.11.220.466
4mwhATPCasein kinase II subunit alpha2.7.11.10.466
4nmbFADBifunctional protein PutA/0.466
1gqtACPRibokinase/0.465
1qvnFRIInterleukin-2/0.465
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.465
2qo9ANPEphrin type-A receptor 32.7.10.10.465
3begANPSRSF protein kinase 12.7.11.10.465
3p62FMNPentaerythritol tetranitrate reductase/0.465
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.465
4qnaX11Serine/threonine-protein kinase 242.7.11.10.465
3iggEFQCyclin-dependent kinase 22.7.11.220.464
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.464
4fki09KCyclin-dependent kinase 22.7.11.220.464
4jr7GNPCasein kinase II subunit alpha2.7.11.10.464
1mp0NADAlcohol dehydrogenase class-31.1.1.10.463
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
2r3lSCWCyclin-dependent kinase 22.7.11.220.463
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.463
2w71L23Biotin carboxylase6.3.4.140.463
3syiFADSulfide-quinone reductase/0.463
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.463
4e730NRMitogen-activated protein kinase 82.7.11.240.463
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.463
2j9mPY8Cyclin-dependent kinase 22.7.11.220.462
2r3mSCXCyclin-dependent kinase 22.7.11.220.462
2w17I19Cyclin-dependent kinase 22.7.11.220.462
3mdmFJZCholesterol 24-hydroxylase/0.462
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
3p8iFMNPentaerythritol tetranitrate reductase/0.462
3r1qX75Cyclin-dependent kinase 22.7.11.220.462
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.462
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.462
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
5cu6ATPCasein kinase II subunit alpha2.7.11.10.462
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.461
3qtxX43Cyclin-dependent kinase 22.7.11.220.461
3vetADPnebramycin 5' synthase6.1.2.20.461
3w5p4OAVitamin D3 receptor/0.461
4e4m0NHTyrosine-protein kinase JAK2/0.461
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.461
4nj32KDCyclin-dependent kinase 22.7.11.220.461
4xiwAZMCarbonic anhydrase, alpha type/0.461
1bygSTUTyrosine-protein kinase CSK/0.460
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1om1IQACasein kinase II subunit alpha2.7.11.10.460
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.460
1urwI1PCyclin-dependent kinase 22.7.11.220.460
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.460
2henADPEphrin type-B receptor 22.7.10.10.460
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.460
2p5uNADUDP-glucose 4-epimerase/0.460
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.460
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.460
2vx17X8Ephrin type-B receptor 42.7.10.10.460
2zdt46CMitogen-activated protein kinase 102.7.11.240.460
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.460
3hl7I47Mitogen-activated protein kinase 14/0.460
3qqfX07Cyclin-dependent kinase 22.7.11.220.460
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.460
3u8w09JMitogen-activated protein kinase 14/0.460
3zep1NXTyrosine-protein kinase JAK32.7.10.20.460
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4gk4L90Ephrin type-A receptor 32.7.10.10.460
4kd11QKCyclin-dependent kinase 22.7.11.220.460
1v0oINRCell division control protein 2 homolog2.7.11.220.459
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.459
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.459
2zbaZBATrichothecene 3-O-acetyltransferase/0.459
3bc3OPTCathepsin L13.4.22.150.459
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.459
4fks46KCyclin-dependent kinase 22.7.11.220.459
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1h1pCMGCyclin-dependent kinase 22.7.11.220.458
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2j0k4STFocal adhesion kinase 12.7.10.20.458
2p33J07Mitogen-activated protein kinase 102.7.11.240.458
2vcmM11Isopenicillin N synthase1.21.3.10.458
3i0pNADMalate dehydrogenase, putative/0.458
3r73X87Cyclin-dependent kinase 22.7.11.220.458
3s1dZIRCytokinin dehydrogenase 11.5.99.120.458
3t2zFADSulfide-quinone reductase/0.458
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.458
1vyzN5BCyclin-dependent kinase 22.7.11.220.457
3blrCPBCyclin-dependent kinase 92.7.11.220.457
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.457
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4fkt48KCyclin-dependent kinase 22.7.11.220.457
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.457
4lopSB4Mitogen-activated protein kinase 14/0.457
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.457
1db1VDXVitamin D3 receptor/0.456
1h63FMNPentaerythritol tetranitrate reductase/0.456
1oitHDTCyclin-dependent kinase 22.7.11.220.456
2of4979Tyrosine-protein kinase Lck2.7.10.20.456
2om9AJAPeroxisome proliferator-activated receptor gamma/0.456
2vx07X7Ephrin type-B receptor 42.7.10.10.456
3blqATPCyclin-dependent kinase 92.7.11.220.456
3cgfJNFMitogen-activated protein kinase 102.7.11.240.456
3r9oZ71Cyclin-dependent kinase 22.7.11.220.456
3zdu38RCyclin-dependent kinase-like 32.7.11.220.456
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.456
4btjADPTau-tubulin kinase 12.7.11.10.456
4eop1ROCyclin-dependent kinase 22.7.11.220.456
4fkq42KCyclin-dependent kinase 22.7.11.220.456
4g160VMCasein kinase I isoform gamma-32.7.11.10.456
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.456
1wbpADPSRSF protein kinase 12.7.11.10.455
2a7r5GPGMP reductase 2/0.455
2bkzSBCCyclin-dependent kinase 22.7.11.220.455
2excJNKMitogen-activated protein kinase 102.7.11.240.455
2uxoTACHTH-type transcriptional regulator TtgR/0.455
2v59LZKBiotin carboxylase6.3.4.140.455
2vwx7X4Ephrin type-B receptor 42.7.10.10.455
3mdvCL6Cholesterol 24-hydroxylase/0.455
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.455
3vrwYS5Vitamin D3 receptor/0.455
4aqc88ATyrosine-protein kinase JAK2/0.455
4ek610KCyclin-dependent kinase 22.7.11.220.455
4fkj11KCyclin-dependent kinase 22.7.11.220.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
4mv8ACPBiotin carboxylase6.3.4.140.455
4qmlANPSerine/threonine-protein kinase 242.7.11.10.455
5cshATPCasein kinase II subunit alpha2.7.11.10.455
1eh4IC1Casein kinase I homolog 12.7.11.10.454
1rfuADPPyridoxal kinase2.7.1.350.454
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.454
2izrBRKCasein kinase I isoform gamma-32.7.11.10.454
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.454
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.454
3qtwX3ACyclin-dependent kinase 22.7.11.220.454
3vrvYSDVitamin D3 receptor/0.454
4lyn1YGCyclin-dependent kinase 22.7.11.220.454
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.454
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.454
1nooCAHCamphor 5-monooxygenase1.14.15.10.453
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.453
2cy0NAPShikimate dehydrogenase (NADP(+))/0.453
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.453
2pmnK51Protein kinase 7/0.453
2pvyACPFibroblast growth factor receptor 2/0.453
3c11GDMATP-dependent molecular chaperone HSP82/0.453
3lq5SLQCyclin-dependent kinase 92.7.11.220.453
3o96IQORAC-alpha serine/threonine-protein kinase2.7.11.10.453
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.453
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.453
4looSB4Mitogen-activated protein kinase 14/0.453
4nb6444Nuclear receptor ROR-gamma/0.453
4ogrADNCyclin-dependent kinase 92.7.11.220.453
1gcoNADGlucose 1-dehydrogenase1.1.1.470.452
1jolFFODihydrofolate reductase1.5.1.30.452
1ke7LS3Cyclin-dependent kinase 22.7.11.220.452
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.452
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.452
2izsBRQCasein kinase I isoform gamma-32.7.11.10.452
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.452
2w1fL0FAurora kinase A2.7.11.10.452
2xikJ60Serine/threonine-protein kinase 252.7.11.10.452
3a7jADPSerine/threonine-protein kinase 242.7.11.10.452
3jynNDPQuinone oxidoreductase/0.452
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.452
3qwjX6ACyclin-dependent kinase 22.7.11.220.452
3umw596Serine/threonine-protein kinase pim-12.7.11.10.452
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4fi1ATPCasein kinase II subunit alpha2.7.11.10.452
4ix6ADPUncharacterized protein/0.452
5cvfATPCasein kinase II subunit alpha2.7.11.10.452
1fxsNAPGDP-L-fucose synthase/0.451
1gij2PUCyclin-dependent kinase 22.7.11.220.451
1m2qMNXCasein kinase II subunit alpha2.7.11.10.451
1zrzBI1Protein kinase C iota type2.7.11.130.451
2hw2RFPRifampin ADP-ribosyl transferase/0.451
2vv9IM9Cyclin-dependent kinase 22.7.11.220.451
3pxyJWSCyclin-dependent kinase 22.7.11.220.451
3zmmF9JTyrosine-protein kinase JAK2/0.451
4bgg844Activin receptor type-12.7.11.300.451
4bgh3I6Cyclin-dependent kinase 22.7.11.220.451
4dgmAGICasein kinase II subunit alpha2.7.11.10.451
4eoi1ROCyclin-dependent kinase 22.7.11.220.451
4lfiGNPCasein kinase II subunit alpha2.7.11.10.451
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.451
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.451
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.451
4qmpDKISerine/threonine-protein kinase 242.7.11.10.451
4xivACPChemotaxis protein CheA2.7.13.30.451
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1dawANPCasein kinase II subunit alpha2.7.11.10.450
1dz6CAMCamphor 5-monooxygenase1.14.15.10.450
1klmSPPGag-Pol polyprotein2.7.7.490.450
1lf3EH5Plasmepsin-23.4.23.390.450
1oiqHDUCyclin-dependent kinase 22.7.11.220.450
1phgMYTCamphor 5-monooxygenase1.14.15.10.450
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.450
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.450
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.450
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.450
2ghlLIBMitogen-activated protein kinase 14/0.450
2r3kSCQCyclin-dependent kinase 22.7.11.220.450
2v7a627Tyrosine-protein kinase ABL12.7.10.20.450
3abaFLICytochrome P450/0.450
3ac1KZITyrosine-protein kinase Lck2.7.10.20.450
3f03FMNPentaerythritol tetranitrate reductase/0.450
3kf7L9GMitogen-activated protein kinase 14/0.450
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3qlsNDPDihydrofolate reductase1.5.1.30.450
3s1cZIRCytokinin dehydrogenase 11.5.99.120.450
3vg9ZMAAdenosine receptor A2a/0.450
3vt7VDXVitamin D3 receptor/0.450
3vt8YI3Vitamin D3 receptor/0.450
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.450
4enhFVXCholesterol 24-hydroxylase/0.450
4g1z0VPVitamin D3 receptor A/0.450
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4ruoBIVVitamin D3 receptor A/0.450
1cqp803Integrin alpha-L/0.449
1culFOKAdenylate cyclase type 2/0.449
1culFOKAdenylate cyclase type 5/0.449
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1gy3ATPCyclin-dependent kinase 22.7.11.220.449
1vyrFMNPentaerythritol tetranitrate reductase/0.449
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.449
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.449
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2vwy7X5Ephrin type-B receptor 42.7.10.10.449
2xnbY8LCyclin-dependent kinase 22.7.11.220.449
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.449
3q9zTXQCasein kinase II subunit alpha2.7.11.10.449
3vt9YI4Vitamin D3 receptor/0.449
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4eooATPCyclin-dependent kinase 22.7.11.220.449
4iteTEYVitamin D3 receptor/0.449
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.449
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.449
1rf7DHFDihydrofolate reductase1.5.1.30.448
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.448
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.448
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.448
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.448
3a783EVVitamin D3 receptor/0.448
3bheBZNGag-Pol polyprotein3.4.23.160.448
3cgcCOACoenzyme A disulfide reductase/0.448
3nszANPCasein kinase II subunit alpha2.7.11.10.448
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.448
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.448
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4nka2K7Fibroblast growth factor receptor 1/0.448
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.448
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1dr3HBIDihydrofolate reductase1.5.1.30.447
1h51FMNPentaerythritol tetranitrate reductase/0.447
1ke8LS4Cyclin-dependent kinase 22.7.11.220.447
1m2pHNACasein kinase II subunit alpha2.7.11.10.447
1pmn984Mitogen-activated protein kinase 102.7.11.240.447
1y0s331Peroxisome proliferator-activated receptor delta/0.447
1yw2PGJMitogen-activated protein kinase 14/0.447
2c6o4SPCyclin-dependent kinase 22.7.11.220.447
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.447
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.447
3ig7EFPCyclin-dependent kinase 22.7.11.220.447
3il1B5DGlutamate receptor 2/0.447
3jziJZLBiotin carboxylase6.3.4.140.447
3l8sBFFMitogen-activated protein kinase 14/0.447
3qtuX44Cyclin-dependent kinase 22.7.11.220.447
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.447
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.447
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1rkhVD2Vitamin D3 receptor/0.446
1vjy460TGF-beta receptor type-12.7.11.300.446
2a4nCOAAac(6')-Ii protein/0.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2pvrANPCasein kinase II subunit alpha2.7.11.10.446
2qo7ANPEphrin type-A receptor 32.7.10.10.446
2vf0F89Thymidylate synthase/0.446
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.446
3at4CCKCasein kinase II subunit alpha2.7.11.10.446
3gobHXXDdmC/0.446
3lpbNVBTyrosine-protein kinase JAK2/0.446
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.446
3p74FMNPentaerythritol tetranitrate reductase/0.446
3qlrNDPDihydrofolate reductase1.5.1.30.446
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.446
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.446
4eos1ROCyclin-dependent kinase 22.7.11.220.446
4g47TZFMycocyclosin synthase1.14.21.90.446
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4jia1K3Tyrosine-protein kinase JAK2/0.446
4wboANWRhodopsin kinase/0.446
5hs1VORLanosterol 14-alpha demethylase/0.446
1blzACVIsopenicillin N synthase1.21.3.10.445
1ia4TQ6Dihydrofolate reductase1.5.1.30.445
1ie8KH1Vitamin D3 receptor/0.445
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2c475IDCasein kinase I isoform gamma-2/0.445
2c5yMTWCyclin-dependent kinase 22.7.11.220.445
2chlDKICasein kinase I isoform gamma-32.7.11.10.445
2exlGDMEndoplasmin/0.445
2hc4VDXVitamin D3 receptor A/0.445
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.445
3cgoJNOMitogen-activated protein kinase 102.7.11.240.445
3gfbNADL-threonine 3-dehydrogenase/0.445
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3slkNDPPolyketide synthase extender module 2/0.445
3sw418KCyclin-dependent kinase 22.7.11.220.445
4b99R4LMitogen-activated protein kinase 72.7.11.240.445
4btmF8ETau-tubulin kinase 12.7.11.10.445
4fkpLS5Cyclin-dependent kinase 22.7.11.220.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4nieNBHNuclear receptor ROR-gamma/0.445
4q72FADBifunctional protein PutA/0.445
4q73FADBifunctional protein PutA/0.445
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
1bsvNDPGDP-L-fucose synthase/0.444
1h50FMNPentaerythritol tetranitrate reductase/0.444
1ia1NDPDihydrofolate reductase1.5.1.30.444
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.444
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
2izuP01Casein kinase I isoform gamma-32.7.11.10.444
3nx4NAPPutative oxidoreductase/0.444
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.444
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3ttjJBIMitogen-activated protein kinase 102.7.11.240.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
3w5rLOAVitamin D3 receptor/0.444
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
4dfrMTXDihydrofolate reductase1.5.1.30.444
4g1y0VOVitamin D3 receptor A/0.444
4hvi19STyrosine-protein kinase JAK32.7.10.20.444
4nfn2KCTau-tubulin kinase 12.7.11.10.444
5e8xSTUTGF-beta receptor type-12.7.11.300.444
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.443
2b7aIZATyrosine-protein kinase JAK2/0.443
2tpsTPSThiamine-phosphate synthase/0.443
2vagV25Dual specificity protein kinase CLK12.7.12.10.443
2x9fX9FEphrin type-B receptor 42.7.10.10.443
3atyFMNProstaglandin F2a synthase/0.443
3cgdCOACoenzyme A disulfide reductase/0.443
3fwjCAMCamphor 5-monooxygenase1.14.15.10.443
3kpkFADSulfide-quinone reductase/0.443
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3p84FMNPentaerythritol tetranitrate reductase/0.443
3rpo24ZCyclin-dependent kinase 22.7.11.220.443
3w0jT08Vitamin D3 receptor/0.443
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.443
4dc0NDPPutative ketoacyl reductase1.3.10.443
4eol1ROCyclin-dependent kinase 22.7.11.220.443
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.443
4jboWPHAurora kinase A2.7.11.10.443
4kbk1QGCasein kinase I isoform delta2.7.11.10.443
5iua6DXAdenosine receptor A2a/0.443
1adfTADAlcohol dehydrogenase E chain1.1.1.10.442
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2c6iDT1Cyclin-dependent kinase 22.7.11.220.442
2wouZZFTGF-beta receptor type-12.7.11.300.442
2xp2VGHALK tyrosine kinase receptor2.7.10.10.442
3a7hATPSerine/threonine-protein kinase 242.7.11.10.442
3at3ATKCasein kinase II subunit alpha2.7.11.10.442
3du8553Glycogen synthase kinase-3 beta2.7.11.260.442
3lqfNADGalactitol dehydrogenase/0.442
3nr4PYVAbscisic acid receptor PYL2/0.442
3qly55VUncharacterized protein/0.442
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.442
4ia7BIVVitamin D3 receptor A/0.442
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.442
4pd6URINucleoside permease/0.442
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.441
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1ikvEFZGag-Pol polyprotein2.7.7.490.441
1kl2FONSerine hydroxymethyltransferase/0.441
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.441
1pjcNADAlanine dehydrogenase/0.441
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.441
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.441
1rx7FOLDihydrofolate reductase1.5.1.30.441
1xddAAYIntegrin alpha-L/0.441
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2cig1DGDihydrofolate reductase1.5.1.30.441
2hb7O1CVitamin D3 receptor/0.441
2hl1A3SThreonine--tRNA ligase6.1.1.30.441
2o4rVD5Vitamin D3 receptor/0.441
2qblCAMCamphor 5-monooxygenase1.14.15.10.441
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.441
3a3bRBFLumazine protein/0.441
3cgeCOACoenzyme A disulfide reductase/0.441
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.441
3m8qDJZGag-Pol polyprotein2.7.7.490.441
3mqe416Prostaglandin G/H synthase 21.14.99.10.441
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.441
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.441
3s79ASDAromatase1.14.14.140.441
4a8v2ANMajor pollen allergen Bet v 1-J/0.441
4eon1ROCyclin-dependent kinase 22.7.11.220.441
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4ic7ANPMitogen-activated protein kinase 72.7.11.240.441
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.441
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.441
4ure1PSCyclohexanol dehydrogenase/0.441
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1dm2HMDCyclin-dependent kinase 22.7.11.220.440
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.440
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.440
1txiTX5Vitamin D3 receptor/0.440
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2b54D05Cyclin-dependent kinase 22.7.11.220.440
2bujSTUSerine/threonine-protein kinase 16/0.440
2pvhP19Casein kinase II subunit alpha2.7.11.10.440
2vn0TDZCytochrome P450 2C8/0.440
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.440
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.440
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.440
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.440
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.440
3vqsJT1Genome polyprotein/0.440
3w6hAZMCarbonic anhydrase 14.2.1.10.440
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.440
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.440
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4ipw1G7Mycocyclosin synthase1.14.21.90.440
4o2bLOCTubulin beta-2B chain/0.440
4rrfA3SThreonine--tRNA ligase6.1.1.30.440
5a3cNADSIR2 family protein/0.440