Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.301.000
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.565
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.535
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.527
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.523
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.508
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.484
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.451