sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 1.000 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.622 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.610 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.587 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.567 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.502 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.501 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.495 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.488 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.485 | |
| 1err | RAL | Estrogen receptor | / | 0.483 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.479 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.478 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.478 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.476 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.475 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.474 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.474 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.472 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.472 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.472 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.471 | |
| 2jfa | RAL | Estrogen receptor | / | 0.470 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.468 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.468 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.466 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.466 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1yin | CM3 | Estrogen receptor | / | 0.465 | |
| 4pd5 | GEO | Nucleoside permease | / | 0.465 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.464 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.463 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.462 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.462 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.461 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.461 | |
| 3qly | 55V | Uncharacterized protein | / | 0.461 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.461 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.459 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.458 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.458 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.458 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.458 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.458 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.457 | |
| 4pd6 | URI | Nucleoside permease | / | 0.457 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.456 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3uq6 | ADN | Putative adenosine kinase | / | 0.456 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.456 | |
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 0.456 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.455 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.455 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.455 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.454 | |
| 2xvu | 9DN | Serum albumin | / | 0.454 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3k90 | A8S | Abscisic acid receptor PYR1 | / | 0.454 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.454 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.454 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.453 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.453 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.453 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.452 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.452 | |
| 2btd | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.452 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.452 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.452 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.452 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.452 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.452 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.452 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.452 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.451 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 2oyf | IAC | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.451 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.451 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.451 | |
| 3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.451 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4e96 | 0NS | Bromodomain-containing protein 4 | / | 0.451 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.451 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.450 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.450 | |
| 1dnp | MHF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.449 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.449 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4q8p | CKR | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.448 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.448 | |
| 2qwq | ADP | Heat shock cognate 71 kDa protein | / | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2ybo | SAH | Methyltransferase | / | 0.447 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.447 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.447 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.447 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.447 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.446 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 2ggq | TTP | Dual sugar-1-phosphate nucleotidylyltransferase | / | 0.446 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.446 | |
| 4fps | 0UX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.446 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ht2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.445 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.445 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.445 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.445 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.445 | |
| 2xvw | 9NR | Serum albumin | / | 0.445 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.445 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.445 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.445 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.445 | |
| 4egn | TWO | Cytochrome P450 | / | 0.445 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1e3k | R18 | Progesterone receptor | / | 0.444 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.444 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.444 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.444 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.444 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.444 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.444 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.444 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.444 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.444 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 5alu | HD2 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 1df8 | BTN | Streptavidin | / | 0.443 | |
| 1gwq | ZTW | Estrogen receptor | / | 0.443 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.443 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.443 | |
| 2w4i | VGA | Glutamate racemase | / | 0.443 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.443 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
| 4meo | 25V | Bromodomain-containing protein 4 | / | 0.443 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.443 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.443 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 2jiz | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.442 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.442 | |
| 4cfk | LY2 | Bromodomain-containing protein 4 | / | 0.442 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.442 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.442 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.441 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ie4 | T44 | Transthyretin | / | 0.441 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.441 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.441 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.441 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.441 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.441 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.441 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.441 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.441 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1axw | MTX | Thymidylate synthase | / | 0.440 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dxr | MST | Reaction center protein L chain | / | 0.440 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1jqi | CAA | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.440 | |
| 1ovm | TPP | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.440 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.440 | |
| 2hvc | LGD | Androgen receptor | / | 0.440 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2p15 | EZT | Estrogen receptor | / | 0.440 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.440 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.440 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.440 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.440 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.440 | |
| 3kdj | A8S | Abscisic acid receptor PYL1 | / | 0.440 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.440 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.440 |