scPDB - Distribution of Binding site Similarity values of 1u71 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1u71	MXA	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1u71	MXA	Dihydrofolate reductase	1.5.1.3	1.000
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.604
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.579
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.577
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.523
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.523
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.516
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.498
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.496
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.494
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.493
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.492
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.488
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.481
1dr3	TAP	Dihydrofolate reductase	1.5.1.3	0.481
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.473
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.471
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.470
1dr2	TAP	Dihydrofolate reductase	1.5.1.3	0.464
3s3v	TOP	Dihydrofolate reductase	1.5.1.3	0.459
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.458
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.457
3kjs	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.456
1bzf	TMQ	Dihydrofolate reductase	1.5.1.3	0.452
3tqa	NDP	Dihydrofolate reductase	/	0.451
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.450
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.446
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.445
1dr5	NAP	Dihydrofolate reductase	1.5.1.3	0.444
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.444
3dga	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.443