scPDB - Distribution of Binding site Similarity values of 1u65 entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1u65	CP0	Acetylcholinesterase	3.1.1.7

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1u65	CP0	Acetylcholinesterase	3.1.1.7	1.000
1eve	E20	Acetylcholinesterase	3.1.1.7	0.657
1w4l	GL8	Acetylcholinesterase	3.1.1.7	0.640
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.640
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.633
1h22	E10	Acetylcholinesterase	3.1.1.7	0.623
1ut6	A8N	Acetylcholinesterase	3.1.1.7	0.597
4arb	C57	Acetylcholinesterase	3.1.1.7	0.597
2xuq	TZ4	Acetylcholinesterase	3.1.1.7	0.596
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.591
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.584
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.583
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.582
4m0f	1YK	Acetylcholinesterase	3.1.1.7	0.581
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.570
2ha6	SCK	Acetylcholinesterase	3.1.1.7	0.569
2xui	TZ5	Acetylcholinesterase	3.1.1.7	0.566
4ara	C56	Acetylcholinesterase	3.1.1.7	0.559
4b7z	Q4Q	Acetylcholinesterase	3.1.1.7	0.559
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.555
1q84	TZ4	Acetylcholinesterase	3.1.1.7	0.555
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.549
2xuk	TZ5	Acetylcholinesterase	3.1.1.7	0.534
2ckm	AA7	Acetylcholinesterase	3.1.1.7	0.529
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.529
1q83	TZ5	Acetylcholinesterase	3.1.1.7	0.527
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.526
2gyw	OBI	Acetylcholinesterase	3.1.1.7	0.525
2cmf	F11	Acetylcholinesterase	3.1.1.7	0.522
2xug	TZ4	Acetylcholinesterase	3.1.1.7	0.516
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.515
2jf0	HBP	Acetylcholinesterase	3.1.1.7	0.512
1qti	GNT	Acetylcholinesterase	3.1.1.7	0.509
2gyu	HI6	Acetylcholinesterase	3.1.1.7	0.509
2xi4	AFT	Acetylcholinesterase	3.1.1.7	0.501
1dx6	GNT	Acetylcholinesterase	3.1.1.7	0.479
1w76	GNT	Acetylcholinesterase	3.1.1.7	0.478
4a16	H34	Acetylcholinesterase	3.1.1.7	0.474
2wu4	HBP	Acetylcholinesterase	3.1.1.7	0.470
1w6r	GNT	Acetylcholinesterase	3.1.1.7	0.461
3zv7	NHG	Acetylcholinesterase	3.1.1.7	0.453