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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1u54ACPActivated CDC42 kinase 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1u54ACPActivated CDC42 kinase 1/1.000
4riyADPEpidermal growth factor receptor2.7.10.10.559
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.542
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.534
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.533
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.530
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.529
1u4dDBQActivated CDC42 kinase 1/0.527
5cnnANPEpidermal growth factor receptor2.7.10.10.527
3zewSTUEphrin type-B receptor 42.7.10.10.525
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.524
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.521
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.519
1bygSTUTyrosine-protein kinase CSK/0.518
2qoqANPEphrin type-A receptor 32.7.10.10.516
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.515
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.515
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.512
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.512
2xa4AZ5Tyrosine-protein kinase JAK2/0.511
5e8wSTUTGF-beta receptor type-12.7.11.300.510
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.508
5e8xSTUTGF-beta receptor type-12.7.11.300.508
4gk3L87Ephrin type-A receptor 32.7.10.10.506
1eh4IC1Casein kinase I homolog 12.7.11.10.504
3c50ADPRhodopsin kinase/0.503
5cnoANPEpidermal growth factor receptor2.7.10.10.502
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.501
2xvdAS6Ephrin type-B receptor 42.7.10.10.500
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.499
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.498
4y95746Tyrosine-protein kinase/0.498
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.497
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.497
2qo9ANPEphrin type-A receptor 32.7.10.10.496
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.496
4i22IREEpidermal growth factor receptor2.7.10.10.496
4y93746Tyrosine-protein kinase/0.496
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.495
4ewhT77Activated CDC42 kinase 1/0.495
3gxlQIGTGF-beta receptor type-12.7.11.300.494
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.493
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.493
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.493
2csnCKICasein kinase I homolog 12.7.11.10.491
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.491
1rw8580TGF-beta receptor type-12.7.11.300.490
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.490
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.490
4gk2L66Ephrin type-A receptor 32.7.10.10.490
4jia1K3Tyrosine-protein kinase JAK2/0.490
2henADPEphrin type-B receptor 22.7.10.10.489
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.489
2yn8STUEphrin type-B receptor 42.7.10.10.489
3nwxKVSGag-Pol polyprotein3.4.23.160.489
3w16P9JAurora kinase A2.7.11.10.489
1xjdSTUProtein kinase C theta type2.7.11.130.488
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.488
4id71G0Activated CDC42 kinase 1/0.488
4wkqIREEpidermal growth factor receptor2.7.10.10.488
2itnANPEpidermal growth factor receptor2.7.10.10.486
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
3vs3VSETyrosine-protein kinase HCK2.7.10.20.486
2j0m4STFocal adhesion kinase 12.7.10.20.485
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.485
3vjoANPEpidermal growth factor receptor2.7.10.10.484
3zh8C58Protein kinase C iota type2.7.11.130.484
4c62XWWTyrosine-protein kinase JAK2/0.484
4fob0USALK tyrosine kinase receptor2.7.10.10.484
4zseANPEpidermal growth factor receptor2.7.10.10.484
3pxkPXKFocal adhesion kinase 12.7.10.20.483
4j97ACPFibroblast growth factor receptor 2/0.483
5aabVGHALK tyrosine kinase receptor2.7.10.10.483
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.482
3vryB43Tyrosine-protein kinase HCK2.7.10.20.482
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.482
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.481
3mdvCL6Cholesterol 24-hydroxylase/0.481
3mtfA3FActivin receptor type-12.7.11.300.481
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.481
4j99ACPFibroblast growth factor receptor 2/0.481
1csnATPCasein kinase I homolog 12.7.11.10.480
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.480
4c57FEFCyclin-G-associated kinase2.7.11.10.479
4hge15VTyrosine-protein kinase JAK2/0.479
4jq8KJ8Epidermal growth factor receptor2.7.10.10.479
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.478
2py3ACPFibroblast growth factor receptor 2/0.478
4jr3KJREpidermal growth factor receptor2.7.10.10.478
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
3lctADPALK tyrosine kinase receptor2.7.10.10.477
5aacVGHALK tyrosine kinase receptor2.7.10.10.477
5e92ANPTGF-beta receptor type-22.7.11.300.477
2etm7PYFocal adhesion kinase 12.7.10.20.476
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.476
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.476
2wotZZGTGF-beta receptor type-12.7.11.300.476
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.476
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.476
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.476
4gk4L90Ephrin type-A receptor 32.7.10.10.476
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.475
3w32W32Epidermal growth factor receptor2.7.10.10.475
4xlvACPInsulin receptor2.7.10.10.475
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.475
5aaaVGHALK tyrosine kinase receptor2.7.10.10.475
2hk51BMTyrosine-protein kinase HCK2.7.10.20.474
2of4979Tyrosine-protein kinase Lck2.7.10.20.474
3c4zADPRhodopsin kinase/0.474
3t113T1Gag-Pol polyprotein3.4.23.160.474
4c58824Cyclin-G-associated kinase2.7.11.10.474
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4qmlANPSerine/threonine-protein kinase 242.7.11.10.474
2of2547Tyrosine-protein kinase Lck2.7.10.20.473
2x9fX9FEphrin type-B receptor 42.7.10.10.473
3vs1VSATyrosine-protein kinase HCK2.7.10.20.473
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.473
1wvxBD4Death-associated protein kinase 12.7.11.10.472
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.472
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
5dt3ATPAurora kinase A2.7.11.10.472
5dt4ATPAurora kinase A2.7.11.10.472
1vjy460TGF-beta receptor type-12.7.11.300.471
2jkqVG8Focal adhesion kinase 12.7.10.20.471
2v7a627Tyrosine-protein kinase ABL12.7.10.20.471
2w1gL0GAurora kinase A2.7.11.10.471
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.470
4fod0UVALK tyrosine kinase receptor2.7.10.10.470
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.470
4g160VMCasein kinase I isoform gamma-32.7.11.10.470
4j95ACPFibroblast growth factor receptor 2/0.470
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.470
1ol5ADPAurora kinase A2.7.11.10.469
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.469
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.469
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.469
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.469
4k33ACPFibroblast growth factor receptor 32.7.10.10.469
1ir3ANPInsulin receptor2.7.10.10.468
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.468
2vwu7X1Ephrin type-B receptor 42.7.10.10.468
1yvj4STTyrosine-protein kinase JAK32.7.10.20.467
2ijmATPFocal adhesion kinase 12.7.10.20.467
3c4wATPRhodopsin kinase/0.467
3lpbNVBTyrosine-protein kinase JAK2/0.467
3poz03PEpidermal growth factor receptor2.7.10.10.467
3t8oATPRhodopsin kinase/0.467
4bb432WEphrin type-B receptor 42.7.10.10.467
4bbe3O4Tyrosine-protein kinase JAK2/0.467
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.467
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.466
2ckeIQUDeath-associated protein kinase 2/0.466
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.466
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.466
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.466
4jr7GNPCasein kinase II subunit alpha2.7.11.10.466
1x8b824Wee1-like protein kinase2.7.10.20.465
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
2w1fL0FAurora kinase A2.7.11.10.465
3a7jADPSerine/threonine-protein kinase 242.7.11.10.465
3frqERYErythromycin resistance repressor protein/0.465
3le62BZCyclin-dependent kinase 22.7.11.220.465
4hvh19RTyrosine-protein kinase JAK32.7.10.20.465
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.465
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
1jpaANPEphrin type-B receptor 22.7.10.10.464
2hckQUETyrosine-protein kinase HCK2.7.10.20.464
3oom507Activin receptor type-12.7.11.300.464
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.464
4c61LMMTyrosine-protein kinase JAK2/0.464
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.464
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.464
4yuqKS1Calmodulin-like domain protein kinase/0.464
1zrzBI1Protein kinase C iota type2.7.11.130.463
2j0lANPFocal adhesion kinase 12.7.10.20.463
2vx17X8Ephrin type-B receptor 42.7.10.10.463
4brxKGWFocal adhesion kinase 12.7.10.20.463
5dr6SKEAurora kinase A2.7.11.10.463
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.462
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.462
1py5PY1TGF-beta receptor type-12.7.11.300.462
2pwlACPFibroblast growth factor receptor 2/0.462
2vwz7X6Ephrin type-B receptor 42.7.10.10.462
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.462
3a62STURibosomal protein S6 kinase beta-12.7.11.10.462
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.462
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.462
4hvi19STyrosine-protein kinase JAK32.7.10.20.462
4i231C9Epidermal growth factor receptor2.7.10.10.462
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.462
4ix6ADPUncharacterized protein/0.462
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.462
5cvhADPCasein kinase II subunit alpha2.7.11.10.462
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2itqITQEpidermal growth factor receptor2.7.10.10.461
3hmm855TGF-beta receptor type-12.7.11.300.461
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.461
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.460
2acxANPG protein-coupled receptor kinase 62.7.11.160.460
2np8CC3Aurora kinase A2.7.11.10.460
3nwq2NCGag-Pol polyprotein3.4.23.160.460
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.460
3w2sW2REpidermal growth factor receptor2.7.10.10.460
4c02TAKActivin receptor type-12.7.11.300.460
4gmy0X5Tyrosine-protein kinase JAK2/0.460
4jboWPHAurora kinase A2.7.11.10.460
4nks2M2Fibroblast growth factor receptor 1/0.460
5dn3ATPAurora kinase A2.7.11.10.460
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.459
2qo7ANPEphrin type-A receptor 32.7.10.10.459
2xb7GUIALK tyrosine kinase receptor2.7.10.10.459
2xp2VGHALK tyrosine kinase receptor2.7.10.10.459
2y6o1N1Ephrin type-A receptor 42.7.10.10.459
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.459
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.459
4ix5ANPUncharacterized protein/0.459
4o0wADNAurora kinase A2.7.11.10.459
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.458
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4bbfO19Tyrosine-protein kinase JAK2/0.458
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.458
4f081RSTyrosine-protein kinase JAK2/0.458
4hvg19QTyrosine-protein kinase JAK32.7.10.20.458
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.458
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.457
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.457
3cr0809Wee1-like protein kinase2.7.10.20.457
3iok1P6Tyrosine-protein kinase JAK2/0.457
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.457
3w33W19Epidermal growth factor receptor2.7.10.10.457
4cd0AWJALK tyrosine kinase receptor2.7.10.10.457
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.457
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.456
1aq1STUCyclin-dependent kinase 22.7.11.220.455
1ol7ADPAurora kinase A2.7.11.10.455
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.455
1pmn984Mitogen-activated protein kinase 102.7.11.240.455
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.455
2eb3ANPEpidermal growth factor receptor2.7.10.10.455
2vd5BI8Myotonin-protein kinase2.7.11.10.455
2vww7X2Ephrin type-B receptor 42.7.10.10.455
2vx07X7Ephrin type-B receptor 42.7.10.10.455
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.455
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3bu5ATPInsulin receptor2.7.10.10.455
4anqVGHALK tyrosine kinase receptor2.7.10.10.455
4aqc88ATyrosine-protein kinase JAK2/0.455
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.455
4jq7KJQEpidermal growth factor receptor2.7.10.10.455
4kb81QOCasein kinase I isoform delta2.7.11.10.455
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.455
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.455
5drdATPAurora kinase A2.7.11.10.455
2gs7ANPEpidermal growth factor receptor2.7.10.10.454
2vgoAD5Aurora kinase B-A2.7.11.10.454
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3d7tSTUTyrosine-protein kinase CSK/0.454
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.454
3k5uPFQAurora kinase A2.7.11.10.454
3nszANPCasein kinase II subunit alpha2.7.11.10.454
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4g2fC07Ephrin type-A receptor 32.7.10.10.454
5dnrATPAurora kinase A2.7.11.10.454
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.453
1om1IQACasein kinase II subunit alpha2.7.11.10.453
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
3c4xATPRhodopsin kinase/0.453
3dds26BGlycogen phosphorylase, liver form2.4.1.10.453
3efwAK8Aurora kinase A2.7.11.10.453
3ggfGVDSerine/threonine-protein kinase 26/0.453
3gu7ADPDeath-associated protein kinase 12.7.11.10.453
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.453
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.453
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4deeADPAurora kinase A2.7.11.10.453
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.453
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.453
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4ji91M3Tyrosine-protein kinase JAK2/0.453
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.453
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.453
5e8ySTUTGF-beta receptor type-22.7.11.300.453
1bwsNDPGDP-L-fucose synthase/0.452
1xl2189Gag-Pol polyprotein3.4.23.160.452
2itvANPEpidermal growth factor receptor2.7.10.10.452
2vwy7X5Ephrin type-B receptor 42.7.10.10.452
2x1nX1NCyclin-dependent kinase 22.7.11.220.452
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.452
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.452
3eljGS7Mitogen-activated protein kinase 82.7.11.240.452
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.452
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.452
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.452
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1m17AQ4Epidermal growth factor receptor2.7.10.10.451
1m2rMNYCasein kinase II subunit alpha2.7.11.10.451
2izrBRKCasein kinase I isoform gamma-32.7.11.10.451
2vwx7X4Ephrin type-B receptor 42.7.10.10.451
3ac1KZITyrosine-protein kinase Lck2.7.10.20.451
3oroAGSSerine/threonine protein kinase/0.451
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.451
4l9i8PRRhodopsin kinase/0.451
4o0sADNAurora kinase A2.7.11.10.451
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1nzdUPGDNA beta-glucosyltransferase/0.450
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
2b7aIZATyrosine-protein kinase JAK2/0.450
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.450
2vu3LZECyclin-dependent kinase 22.7.11.220.450
3bheBZNGag-Pol polyprotein3.4.23.160.450
3gubGUBDeath-associated protein kinase 12.7.11.10.450
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3sheI85MAP kinase-activated protein kinase 32.7.11.10.450
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.450
4k8aK8AFocal adhesion kinase 12.7.10.20.450
4tuvCPZCytochrome P450 1191.140.450
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.450
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
1xddAAYIntegrin alpha-L/0.449
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.449
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.449
3rvg17PTyrosine-protein kinase JAK2/0.449
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4enhFVXCholesterol 24-hydroxylase/0.449
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.449
4qnyANPMitogen activated protein kinase, putative/0.449
4wboANWRhodopsin kinase/0.449
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.448
2q61SF1Peroxisome proliferator-activated receptor gamma/0.448
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.448
2x3nFADProbable FAD-dependent monooxygenase/0.448
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.448
3gc9B45Mitogen-activated protein kinase 112.7.11.240.448
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.448
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ansVGHALK tyrosine kinase receptor2.7.10.10.448
4aotGW8Serine/threonine-protein kinase 102.7.11.10.448
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.448
4erwSTUCyclin-dependent kinase 22.7.11.220.448
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.448
4q71FADBifunctional protein PutA/0.448
4utdACPAurora kinase A2.7.11.10.448
5l8lADPAurora kinase A2.7.11.10.448
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.447
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.447
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.447
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.447
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.447
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.447
3nynSGVG protein-coupled receptor kinase 62.7.11.160.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.447
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.447
4iva1J5Tyrosine-protein kinase JAK2/0.447
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.447
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.447
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.446
2hog710Serine/threonine-protein kinase Chk12.7.11.10.446
2qocANPEphrin type-A receptor 32.7.10.10.446
3orkAGSSerine/threonine protein kinase/0.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3zze6XPHepatocyte growth factor receptor2.7.10.10.446
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4ccbOFGALK tyrosine kinase receptor2.7.10.10.446
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.446
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.446
4hgs15GCasein kinase I isoform gamma-32.7.11.10.446
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.446
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.445
2excJNKMitogen-activated protein kinase 102.7.11.240.445
2izuP01Casein kinase I isoform gamma-32.7.11.10.445
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.445
2yfxVGHALK tyrosine kinase receptor2.7.10.10.445
3i60E86Mitogen-activated protein kinase 12.7.11.240.445
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.445
3zmmF9JTyrosine-protein kinase JAK2/0.445
4anmWULCasein kinase II subunit alpha2.7.11.10.445
5awmANPStress-activated protein kinase JNK2.7.11.240.445
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1mqbANPEphrin type-A receptor 22.7.10.10.444
1uyePU9Heat shock protein HSP 90-alpha/0.444
2bfyH1NAurora kinase B-A2.7.11.10.444
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.444
2wxvWXVCyclin-dependent kinase 22.7.11.220.444
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.444
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.444
3a1nNADNDP-sugar epimerase/0.444
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.444
3rm618ZCyclin-dependent kinase 22.7.11.220.444
4c59FEFCyclin-G-associated kinase2.7.11.10.444
4f630S7Fibroblast growth factor receptor 1/0.444
4gg70J8Hepatocyte growth factor receptor2.7.10.10.444
4jrvKJVEpidermal growth factor receptor2.7.10.10.444
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.444
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.443
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.443
2p33J07Mitogen-activated protein kinase 102.7.11.240.443
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.443
3a4pDFQHepatocyte growth factor receptor2.7.10.10.443
3nxe2NCProtease/0.443
4b0gVEKAurora kinase A2.7.11.10.443
4eooATPCyclin-dependent kinase 22.7.11.220.443
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.443
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.443
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.443
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.443
4qmySTUSerine/threonine-protein kinase 242.7.11.10.443
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
5dpvSKEAurora kinase A2.7.11.10.443
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
1pkdUCNCyclin-dependent kinase 22.7.11.220.442
2x4f16XMyosin light chain kinase family member 42.7.11.10.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.442
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.442
3a7hATPSerine/threonine-protein kinase 242.7.11.10.442
3gwfFADCyclohexanone monooxygenase/0.442
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.442
4qgiROCGag-Pol polyprotein3.4.23.160.442
1k6cMK1Gag-Pol polyprotein3.4.23.160.441
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.441
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.441
2wipP49Cyclin-dependent kinase 22.7.11.220.441
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.441
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.441
2x6dX6DAurora kinase A2.7.11.10.441
3cgfJNFMitogen-activated protein kinase 102.7.11.240.441
3d1yROCGag-Pol polyprotein3.4.23.160.441
3gu6ADPDeath-associated protein kinase 12.7.11.10.441
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3umw596Serine/threonine-protein kinase pim-12.7.11.10.441
4bcmT7ZCyclin-dependent kinase 22.7.11.220.441
4dcaADPAminoglycoside phosphotransferase/0.441
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4foc0UUALK tyrosine kinase receptor2.7.10.10.441
4fuxE75Mitogen-activated protein kinase 12.7.11.240.441
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4nka2K7Fibroblast growth factor receptor 1/0.441
1dawANPCasein kinase II subunit alpha2.7.11.10.440
1k6vXN2Gag-Pol polyprotein3.4.23.160.440
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.440
1pjkANPCasein kinase II subunit alpha2.7.11.10.440
2aquDR7Gag-Pol polyprotein3.4.23.160.440
2c6eHPMAurora kinase A2.7.11.10.440
2ittAEEEpidermal growth factor receptor2.7.10.10.440
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.440
2nnpROCProtease/0.440
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.440
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.440
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4ivd15TTyrosine-protein kinase JAK1/0.440
4j5j478Gag-Pol polyprotein3.4.23.160.440
4l9kEHFSerum albumin/0.440
4uymVOR14-alpha sterol demethylase Cyp51B/0.440