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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1trbFADThioredoxin reductase1.8.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1trbFADThioredoxin reductase1.8.1.91.000
1tdeFADThioredoxin reductase1.8.1.90.802
1cl0FADThioredoxin reductase1.8.1.90.704
1tdfFADThioredoxin reductase1.8.1.90.693
4jnqFDAThioredoxin reductase/0.518
3itjFADThioredoxin reductase 11.8.1.90.492
4ccrFADThioredoxin reductase/0.478
2q0kFADThioredoxin reductase1.8.1.90.475
3ctyFADProbable thioredoxin reductase/0.466
4ccqFADThioredoxin reductase/0.462
1fl2FADAlkyl hydroperoxide reductase subunit F1.8.10.458
4up3FADThioredoxin reductase/0.454
4a5lFADThioredoxin reductase/0.448
4cbqFADThioredoxin reductase/0.446
2q0lFADThioredoxin reductase1.8.1.90.445
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.443
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.442
1greFADGlutathione reductase, mitochondrial1.8.1.70.441