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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1tkzH16Gag-Pol polyprotein2.7.7.49

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1tkzH16Gag-Pol polyprotein2.7.7.491.000
1tl3H20Gag-Pol polyprotein2.7.7.490.824
1tktH12Gag-Pol polyprotein2.7.7.490.769
1tl1H18Gag-Pol polyprotein2.7.7.490.711
1revTB9Gag-Pol polyprotein2.7.7.490.700
1s1wUC1Gag-Pol polyprotein2.7.7.490.656
2opqHBQGag-Pol polyprotein2.7.7.490.641
1vruAAPGag-Pol polyprotein2.7.7.490.636
1rt4UC1Gag-Pol polyprotein2.7.7.490.618
4ko0JLJGag-Pol polyprotein2.7.7.490.612
1ikwEFZGag-Pol polyprotein2.7.7.490.607
2zd1T27Gag-Pol polyprotein2.7.7.490.604
1hpzAAPGag-Pol polyprotein2.7.7.490.601
1hnvTBOGag-Pol polyprotein2.7.7.490.599
1s6qTPBGag-Pol polyprotein2.7.7.490.598
4ig3T27Gag-Pol polyprotein2.7.7.490.597
1ikvEFZGag-Pol polyprotein2.7.7.490.595
3is9AC7Gag-Pol polyprotein2.7.7.490.595
1rt5UC2Gag-Pol polyprotein2.7.7.490.594
4id5T27Gag-Pol polyprotein2.7.7.490.592
3i0rRT3Gag-Pol polyprotein2.7.7.490.590
4i2pG73Gag-Pol polyprotein2.7.7.490.589
1c1bGCAGag-Pol polyprotein2.7.7.490.587
1tkxGWBGag-Pol polyprotein2.7.7.490.587
4kko1REGag-Pol polyprotein2.7.7.490.582
1ikxPNUGag-Pol polyprotein2.7.7.490.580
2hnzPC0Gag-Pol polyprotein2.7.7.490.579
2rf2MRXGag-Pol polyprotein2.7.7.490.576
2ban357Gag-Pol polyprotein2.7.7.490.575
4ifvT27Gag-Pol polyprotein2.7.7.490.575
1s9eADBGag-Pol polyprotein2.7.7.490.574
1tvrTB9Gag-Pol polyprotein2.7.7.490.571
2vg5NNCGag-Pol polyprotein2.7.7.490.569
3megT27Gag-Pol polyprotein2.7.7.490.569
1ikyMSDGag-Pol polyprotein2.7.7.490.568
2oppHBQGag-Pol polyprotein2.7.7.490.568
1hniAAAGag-Pol polyprotein2.7.7.490.564
2vg7NNIGag-Pol polyprotein2.7.7.490.564
4g1qT27Gag-Pol polyprotein2.7.7.490.564
1eetBFUGag-Pol polyprotein2.7.7.490.562
2hndNVPGag-Pol polyprotein2.7.7.490.562
3meeT27Gag-Pol polyprotein2.7.7.490.562
1rt7UC4Gag-Pol polyprotein2.7.7.490.561
3irxUDRGag-Pol polyprotein2.7.7.490.560
4i7fNVEGag-Pol polyprotein2.7.7.490.560
3ffi3OBGag-Pol polyprotein2.7.7.490.559
3qlhT27Gag-Pol polyprotein2.7.7.490.557
1rt2TNKGag-Pol polyprotein2.7.7.490.555
1fk9EFZGag-Pol polyprotein2.7.7.490.551
1jlgUC1Gag-Pol polyprotein2.7.7.490.551
1hquHBYGag-Pol polyprotein2.7.7.490.550
2ze2T27Gag-Pol polyprotein2.7.7.490.540
3i0sRT7Gag-Pol polyprotein2.7.7.490.540
1s1tUC1Gag-Pol polyprotein2.7.7.490.537
1ep4S11Gag-Pol polyprotein2.7.7.490.536
5cyqT27Gag-Pol polyprotein2.7.7.490.536
3nbpJGZGag-Pol polyprotein2.7.7.490.535
3dleGFAGag-Pol polyprotein2.7.7.490.529
2ic3HBYGag-Pol polyprotein2.7.7.490.527
2opsHBQGag-Pol polyprotein2.7.7.490.520
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.520
3dmjGWEPol protein/0.518
3m8qDJZGag-Pol polyprotein2.7.7.490.517
4i2q1BTGag-Pol polyprotein2.7.7.490.517
3lanKBTGag-Pol polyprotein2.7.7.490.516
1jlaTNKGag-Pol polyprotein2.7.7.490.511
1fkoEFZGag-Pol polyprotein2.7.7.490.510
1jlqSBNGag-Pol polyprotein2.7.7.490.508
3lalKRVGag-Pol polyprotein2.7.7.490.505
1jlcFTCGag-Pol polyprotein2.7.7.490.504
1klmSPPGag-Pol polyprotein2.7.7.490.504
4rw6494Gag-Pol polyprotein2.7.7.490.504
4kfbT27Gag-Pol polyprotein2.7.7.490.500
1v7aFRCAdenosine deaminase3.5.4.40.499
1l2jETCEstrogen receptor beta/0.497
3mec65BGag-Pol polyprotein2.7.7.490.494
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
1rt1MKCGag-Pol polyprotein2.7.7.490.491
1s1vTNKGag-Pol polyprotein2.7.7.490.491
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.489
4nmbFADBifunctional protein PutA/0.487
3lfcZ86Mitogen-activated protein kinase 14/0.485
1oitHDTCyclin-dependent kinase 22.7.11.220.484
2zjwREFCasein kinase II subunit alpha2.7.11.10.483
1osvCHCBile acid receptor/0.482
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
3p6oETGCamphor 5-monooxygenase1.14.15.10.482
4ejh0QACytochrome P450 2A131.14.14.10.482
3ctj320Hepatocyte growth factor receptor2.7.10.10.479
3med65BGag-Pol polyprotein2.7.7.490.479
2b5j3ACGag-Pol polyprotein2.7.7.490.478
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.478
3cv9VDXVitamin D3 dihydroxylase/0.478
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.477
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
2oprHBQGag-Pol polyprotein2.7.7.490.476
3at4CCKCasein kinase II subunit alpha2.7.11.10.476
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.476
1ot7IU5Bile acid receptor/0.475
1e7aPFLSerum albumin/0.474
3qqkX02Cyclin-dependent kinase 22.7.11.220.474
3rak03ZCyclin-dependent kinase 22.7.11.220.474
1aoeGW3Dihydrofolate reductase1.5.1.30.473
1dkfBMSRetinoic acid receptor alpha/0.473
3m0eATPTranscriptional regulator (NtrC family)/0.473
4fkv61KCyclin-dependent kinase 22.7.11.220.473
3juhANPCasein kinase II subunit alpha2.7.11.10.472
3rni21ZCyclin-dependent kinase 22.7.11.220.472
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
1qxlFR8Adenosine deaminase3.5.4.40.471
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.471
2w05FRTCyclin-dependent kinase 22.7.11.220.471
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3lamKRPGag-Pol polyprotein2.7.7.490.471
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
2bxqIMNSerum albumin/0.470
3bejMUFBile acid receptor/0.470
4bb3KKAIsopenicillin N synthase1.21.3.10.470
4xwtU5PRibonuclease J/0.470
4ocvANPAminoglycoside phosphotransferase/0.469
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.468
3bgrT27Gag-Pol polyprotein2.7.7.490.468
4a9mP9MBromodomain-containing protein 2/0.468
3srrQ20Dihydrofolate reductase1.5.1.30.467
4o761M3Bromodomain-containing protein 4/0.467
4ogrADNCyclin-dependent kinase 92.7.11.220.467
1n4hREANuclear receptor ROR-beta/0.466
1ot7CHCBile acid receptor/0.466
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.466
2pvnP63Casein kinase II subunit alpha2.7.11.10.466
2vv9IM9Cyclin-dependent kinase 22.7.11.220.466
3r6pA8SAbscisic acid receptor PYL10/0.466
3slkNDPPolyketide synthase extender module 2/0.466
5cvfATPCasein kinase II subunit alpha2.7.11.10.466
3rmf20ZCyclin-dependent kinase 22.7.11.220.465
1db1VDXVitamin D3 receptor/0.464
1w83L11Mitogen-activated protein kinase 14/0.464
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.464
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.464
1r9oFLPCytochrome P450 2C9/0.463
2cciATPCyclin-dependent kinase 22.7.11.220.463
2tscCB3Thymidylate synthase/0.463
3zk5Z18Cytochrome P450 monooxygenase PikC/0.463
4mfb29TGag-Pol polyprotein2.7.7.490.463
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.462
1lhvNOGSex hormone-binding globulin/0.461
1uykPUXHeat shock protein HSP 90-alpha/0.461
3inwJZBHeat shock protein HSP 90-alpha/0.461
3njoP2MAbscisic acid receptor PYR1/0.461
4e37NDPCatalase1.11.1.60.461
5uviZMAAdenosine receptor A2a/0.461
5k2bZMAAdenosine receptor A2a/0.461
1o5rFR9Adenosine deaminase3.5.4.40.460
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.460
2p4yC03Peroxisome proliferator-activated receptor gamma/0.460
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.460
2z7gEH9Adenosine deaminase3.5.4.40.460
4anmWULCasein kinase II subunit alpha2.7.11.10.460
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
3dl9V2HVitamin D 25-hydroxylase/0.459
3eek53SUncharacterized protein/0.459
3mdmFJZCholesterol 24-hydroxylase/0.459
3nefPYVAbscisic acid receptor PYL1/0.459
3p9tTCLRepressor/0.459
3u4uLNHCasein kinase II subunit alpha2.7.11.10.459
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.459
4jx1CAHCamphor 5-monooxygenase1.14.15.10.459
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.458
3be9P04Casein kinase II subunit alpha2.7.11.10.458
3jwm5WBDihydrofolate reductase/0.458
3m8p65BGag-Pol polyprotein2.7.7.490.458
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.458
3sruQ26Dihydrofolate reductase1.5.1.30.458
4jx1CAMCamphor 5-monooxygenase1.14.15.10.458
1ek2CDUBifunctional epoxide hydrolase 2/0.457
1kb9SMACytochrome b/0.457
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2bxmIMNSerum albumin/0.457
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.457
2jedLG8Protein kinase C theta type2.7.11.130.457
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.457
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3vtdTKDVitamin D3 receptor/0.457
4erwSTUCyclin-dependent kinase 22.7.11.220.457
4jvmXDIEstrogen sulfotransferase2.8.2.40.457
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.457
4o701QKBromodomain-containing protein 4/0.457
4o71CPBBromodomain-containing protein 4/0.457
5e8xSTUTGF-beta receptor type-12.7.11.300.457
1kkq471Peroxisome proliferator-activated receptor alpha/0.456
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.456
2r64740Cyclin-dependent kinase 22.7.11.220.456
2wi72KLHeat shock protein HSP 90-alpha/0.456
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.456
3t14FADSulfide-quinone reductase/0.456
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.456
4h4m494Gag-Pol polyprotein2.7.7.490.456
1ie9VDXVitamin D3 receptor/0.455
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
1rdtL79Retinoic acid receptor RXR-alpha/0.455
2i0ePDSProtein kinase C beta type2.7.11.130.455
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.455
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.455
3gc9B45Mitogen-activated protein kinase 112.7.11.240.455
3hz5Z64Heat shock protein HSP 90-alpha/0.455
3q5kD1UHeat shock protein 83-1/0.455
3vt9YI4Vitamin D3 receptor/0.455
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.455
4jvlESTEstrogen sulfotransferase2.8.2.40.455
4nh82LCHeat shock protein HSP 90-alpha/0.455
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.455
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.454
2fzhDH1Dihydrofolate reductase1.5.1.30.454
2hamC33Vitamin D3 receptor/0.454
2hb7O1CVitamin D3 receptor/0.454
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.454
3d7kD7KBenzaldehyde lyase/0.454
3nj0PYVAbscisic acid receptor PYL2/0.454
3q9xEMOCasein kinase II subunit alpha2.7.11.10.454
3qlxQLRUncharacterized protein/0.454
3qly55VUncharacterized protein/0.454
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.454
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4othDRNSerine/threonine-protein kinase N1/0.454
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1lwlDSOCamphor 5-monooxygenase1.14.15.10.453
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
2jn3JN3Fatty acid-binding protein, liver/0.453
3c3xNAPEugenol synthase 11.1.1.3180.453
3dhoB2MStreptogramin A acetyltransferase2.3.10.453
3p3zP3ZPutative cytochrome P450/0.453
3vt7VDXVitamin D3 receptor/0.453
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.453
1aq1STUCyclin-dependent kinase 22.7.11.220.452
1rd4L08Integrin alpha-L/0.452
1s0zEB1Vitamin D3 receptor/0.452
2a0cCK9Cyclin-dependent kinase 22.7.11.220.452
2c7xNRBCytochrome P450 monooxygenase PikC/0.452
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2hb8MVDVitamin D3 receptor/0.452
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.452
2vu3LZECyclin-dependent kinase 22.7.11.220.452
3bfb9ODPheromone-binding protein ASP1/0.452
3gcq1BUMitogen-activated protein kinase 14/0.452
3iw5DF3Mitogen-activated protein kinase 14/0.452
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3sz0FADSulfide-quinone reductase/0.452
3tubFPUTyrosine-protein kinase SYK2.7.10.20.452
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.451
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.451
2bxoOPBSerum albumin/0.451
2fszOHTEstrogen receptor beta/0.451
2hw2RFPRifampin ADP-ribosyl transferase/0.451
2pvlP55Casein kinase II subunit alpha2.7.11.10.451
2vtqLZACyclin-dependent kinase 22.7.11.220.451
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3lltANPProtein serine/threonine kinase-1/0.451
3negPYVAbscisic acid receptor PYL1/0.451
3nmpPYVAbscisic acid receptor PYL2/0.451
3vrwYS5Vitamin D3 receptor/0.451
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.451
3w0yDS4Vitamin D3 receptor/0.451
3zcw4A2Kinesin-like protein KIF11/0.451
4af3VX6Aurora kinase B2.7.11.10.451
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4g7gVFVLanosterol 14-alpha-demethylase/0.451
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.451
4nb6444Nuclear receptor ROR-gamma/0.451
4qa0SHHHistone deacetylase 83.5.1.980.451
6coxS58Prostaglandin G/H synthase 21.14.99.10.451
1m7aMQUDihydrofolate reductase1.5.1.30.450
1oirHDYCyclin-dependent kinase 22.7.11.220.450
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2uzbC75Cyclin-dependent kinase 22.7.11.220.450
3b9lAZZSerum albumin/0.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3s1h56ZCyclin-dependent kinase 22.7.11.220.450
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.450
1jioDEB6-deoxyerythronolide B hydroxylase/0.449
1uy8PU5Heat shock protein HSP 90-alpha/0.449
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.449
1yqj6NPMitogen-activated protein kinase 14/0.449
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.449
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2ydwWSHBromodomain-containing protein 2/0.449
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.449
3dd125DGlycogen phosphorylase, liver form2.4.1.10.449
3h1jSMACytochrome b/0.449
3iaeD7KBenzaldehyde lyase/0.449
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.449
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
5fbhTCRExtracellular calcium-sensing receptor/0.449
5k2aZMAAdenosine receptor A2a/0.449
1ndzFR5Adenosine deaminase3.5.4.40.448
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
1q5dEPBEpothilone C/D epoxidase1.140.448
1rf9DBRCamphor 5-monooxygenase1.14.15.10.448
1sj0E4DEstrogen receptor/0.448
2duv371Cyclin-dependent kinase 22.7.11.220.448
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.448
2vf0F89Thymidylate synthase/0.448
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.448
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.448
2w4qCBWProstaglandin reductase 21.3.1.480.448
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.448
2yee2ECHeat shock protein HSP 90-alpha/0.448
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.448
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.448
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.448
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3qtuX44Cyclin-dependent kinase 22.7.11.220.448
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3vtcTK3Vitamin D3 receptor/0.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
4iv41GSEstrogen receptor/0.448
4otyLURProstaglandin G/H synthase 21.14.99.10.448
4xe606UDihydrofolate reductase1.5.1.30.448
5kgpACOPredicted acetyltransferase/0.448
1pd9CO4Dihydrofolate reductase1.5.1.30.447
1uyfPU1Heat shock protein HSP 90-alpha/0.447
1yc2NADNAD-dependent protein deacylase 2/0.447
2ewaSB2Mitogen-activated protein kinase 14/0.447
3bfa9ODOdorant binding protein ASP1/0.447
3lfqA28Cyclin-dependent kinase 22.7.11.220.447
3mnrSD1Heat shock protein HSP 90-alpha/0.447
3oom507Activin receptor type-12.7.11.300.447
3vspEK8Peroxisome proliferator-activated receptor gamma/0.447
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.447
4apuA2KProgesterone receptor/0.447
4bchT7ZCyclin-dependent kinase 92.7.11.220.447
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4oavACP2-5A-dependent ribonuclease3.1.260.447
4q5hANPProtein kinase OspG2.70.447
4qa1B3NHistone deacetylase 83.5.1.980.447
1fmjRTLRetinol dehydratase/0.446
1lriCLRBeta-elicitin cryptogein/0.446
1s19MC9Vitamin D3 receptor/0.446
2vr1ATFBiotin carboxylase6.3.4.140.446
2w3vTOPDihydrofolate reductase/0.446
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.446
3fc6REARetinoic acid receptor RXR-alpha/0.446
3ictADPCoenzyme A disulfide reductase/0.446
3s7a684Dihydrofolate reductase1.5.1.30.446
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.446
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
4iui1GQEstrogen receptor/0.446
4rrxLURProstaglandin G/H synthase 21.14.99.10.446
4ryvZEAProtein LlR18A/0.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
5cshATPCasein kinase II subunit alpha2.7.11.10.446
5iua6DXAdenosine receptor A2a/0.446
1cjuFOKAdenylate cyclase type 2/0.445
1cjuFOKAdenylate cyclase type 5/0.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1rjkVDZVitamin D3 receptor/0.445
1sqvUHDCytochrome b/0.445
1uyhPU0Heat shock protein HSP 90-alpha/0.445
2bheBRYCyclin-dependent kinase 22.7.11.220.445
2cduFADNADH oxidase/0.445
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.445
2ovhAS0Progesterone receptor/0.445
2pmdGNPTranslation initiation factor 2 subunit gamma/0.445
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.445
2wsaMYAGlycylpeptide N-tetradecanoyltransferase/0.445
3a1l2CCCytochrome P450/0.445
3cd2MTXDihydrofolate reductase1.5.1.30.445
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3koo24DBifunctional epoxide hydrolase 23.3.2.100.445
3kpzZNEVitamin D3 receptor/0.445
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.445
3sw719KCyclin-dependent kinase 22.7.11.220.445
3syiFADSulfide-quinone reductase/0.445
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.445
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.445
4eoi1ROCyclin-dependent kinase 22.7.11.220.445
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.445
4pkl1GHUncharacterized protein/0.445
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.445
1dajMOTDihydrofolate reductase1.5.1.30.444
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.444
1m13HYFNuclear receptor subfamily 1 group I member 2/0.444
1pkfEPDEpothilone C/D epoxidase1.140.444
2aibERGBeta-elicitin cinnamomin/0.444
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2fvdLIACyclin-dependent kinase 22.7.11.220.444
2fziDH3Dihydrofolate reductase1.5.1.30.444
2ibzSMACytochrome b/0.444
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
3c13EMOCasein kinase II subunit alpha2.7.11.10.444
3le62BZCyclin-dependent kinase 22.7.11.220.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3nga3NGCasein kinase II subunit alpha2.7.11.10.444
3njoPYVAbscisic acid receptor PYR1/0.444
3qlrQLRDihydrofolate reductase1.5.1.30.444
3sqq99ZCyclin-dependent kinase 22.7.11.220.444
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.444
3zuxTCHTransporter/0.444
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.444
4c2yMYAGlycylpeptide N-tetradecanoyltransferase 1/0.444
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.444
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.444
4ii5ADPCyclin-dependent kinase 22.7.11.220.444
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.444
4qe6JN3Bile acid receptor/0.444
5k2cZMAAdenosine receptor A2a/0.444
1bygSTUTyrosine-protein kinase CSK/0.443
1cx2S58Prostaglandin G/H synthase 21.14.99.10.443
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.443
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1oiyN41Cyclin-dependent kinase 22.7.11.220.443
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.443
1uydPU8Heat shock protein HSP 90-alpha/0.443
1zhzERGOxysterol-binding protein homolog 4/0.443
2bbqPFGThymidylate synthase/0.443
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.443
2oyuIMSProstaglandin G/H synthase 11.14.99.10.443
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.443
2wgjVGHHepatocyte growth factor receptor2.7.10.10.443
2wleCOAPolysialic acid O-acetyltransferase/0.443
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.443
3ddw055Glycogen phosphorylase, liver form2.4.1.10.443
3mtfA3FActivin receptor type-12.7.11.300.443
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3ol5SAWCamphor 5-monooxygenase1.14.15.10.443
3p2oNADBifunctional protein FolD/0.443
3p6mDSOCamphor 5-monooxygenase1.14.15.10.443
3rk708ZCyclin-dependent kinase 22.7.11.220.443
3w0aDS5Vitamin D3 receptor/0.443
3zw9T1GPeroxisomal bifunctional enzyme1.1.1.350.443
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.443
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.443
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4bcqTJFCyclin-dependent kinase 22.7.11.220.443
4ez8DHFThymidylate synthase2.1.1.450.443
4g210VPVitamin D3 receptor A/0.443
4g95OAGDihydrofolate reductase1.5.1.30.443
4grb0XGCasein kinase II subunit alpha2.7.11.10.443
4jlj1NMDeoxycytidine kinase2.7.1.740.443
4rrwLURProstaglandin G/H synthase 21.14.99.10.443
4rrzLURProstaglandin G/H synthase 21.14.99.10.443
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.443
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.443
1bq1CB3Thymidylate synthase/0.442
1ezvSMACytochrome b/0.442
1fmlRTLRetinol dehydratase/0.442
1kt3RTLRetinol-binding protein 4/0.442
1ppjANYCytochrome b/0.442
1xqcAEJEstrogen receptor/0.442
2c5nCK8Cyclin-dependent kinase 22.7.11.220.442
2hcdBIVVitamin D3 receptor A/0.442
2ij7TPFMycocyclosin synthase1.14.21.90.442
2po7CHDFerrochelatase, mitochondrial4.99.1.10.442
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2w17I19Cyclin-dependent kinase 22.7.11.220.442
2zl9VDAVitamin D3 receptor/0.442
3a8iC2FAminomethyltransferase2.1.2.100.442
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.442
3nr4PYVAbscisic acid receptor PYL2/0.442
3oquA8SAbscisic acid receptor PYL9/0.442
3s79ASDAromatase1.14.14.140.442
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.442
3t8xT8XT-cell surface glycoprotein CD1b/0.442
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.442
3w5rLOAVitamin D3 receptor/0.442
4cd2FOLDihydrofolate reductase1.5.1.30.442
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.442
4nr42LKCREB-binding protein/0.442
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.442
3rfmCFFAdenosine receptor A2a/0.442
1errRALEstrogen receptor/0.441
1fm4DXCMajor pollen allergen Bet v 1-L/0.441
1fm99CRRetinoic acid receptor RXR-alpha/0.441
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1kzjCB3Thymidylate synthase/0.441
1uymPU3Heat shock protein HSP 90-beta/0.441
2h96893Mitogen-activated protein kinase 82.7.11.240.441
2o4rVD5Vitamin D3 receptor/0.441
2qe4JJ3Estrogen receptor/0.441
2ykiYKIHeat shock protein HSP 90-alpha/0.441
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.441
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.441
3mdvCL6Cholesterol 24-hydroxylase/0.441
3nup3NUCyclin-dependent kinase 62.7.11.220.441
3pqbVGPPutative oxidoreductase/0.441
3ruqADPChaperonin/0.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.441
4aotGW8Serine/threonine-protein kinase 102.7.11.10.441
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4h9814QUncharacterized protein/0.441
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
4qa2SHHHistone deacetylase 83.5.1.980.441
5d1bTSNHistone deacetylase 83.5.1.980.441
1ju6LYAThymidylate synthase2.1.1.450.440
1txiTX5Vitamin D3 receptor/0.440
1umlFR4Adenosine deaminase3.5.4.40.440
2cchATPCyclin-dependent kinase 22.7.11.220.440
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
2om9AJAPeroxisome proliferator-activated receptor gamma/0.440
2q70DC8Estrogen receptor/0.440
2rqfJH3Hemolymph juvenile hormone binding protein/0.440
2vagV25Dual specificity protein kinase CLK12.7.12.10.440
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
2z3uCRRCytochrome P450/0.440
2zb45OPProstaglandin reductase 21.3.1.480.440
3h0a9RARetinoic acid receptor RXR-alpha/0.440
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.440
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3rusADPChaperonin/0.440
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
3sw418KCyclin-dependent kinase 22.7.11.220.440
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3vrvYSDVitamin D3 receptor/0.440
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4bgg844Activin receptor type-12.7.11.300.440
4bgq38RCyclin-dependent kinase-like 52.7.11.220.440
4eor4SPCyclin-dependent kinase 22.7.11.220.440
4g2h0VQVitamin D3 receptor A/0.440
4gg70J8Hepatocyte growth factor receptor2.7.10.10.440
4ib4ERM5-hydroxytryptamine receptor 2B/0.440
4jrvKJVEpidermal growth factor receptor2.7.10.10.440
4ly91YYGlucokinase regulatory protein/0.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440
4rujVDXVitamin D3 receptor A/0.440
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.440