scPDB - Distribution of Binding site Similarity values of 1tkb entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1tkb	N1T	Transketolase 1	2.2.1.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1tkb	N1T	Transketolase 1	2.2.1.1	1.000
1ngs	TPP	Transketolase 1	2.2.1.1	0.700
1tkc	M6T	Transketolase 1	2.2.1.1	0.692
1ay0	TPP	Transketolase 1	2.2.1.1	0.663
1itz	TPP	Transketolase, chloroplastic	2.2.1.1	0.585
3upt	TPP	Transketolase	/	0.583
2r5n	TPP	Transketolase 1	/	0.565
1tka	N3T	Transketolase 1	2.2.1.1	0.562
1trk	TPP	Transketolase 1	2.2.1.1	0.562
3rim	TPP	Transketolase	2.2.1.1	0.527
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.497
2g25	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.482
2o1s	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.469
1umc	TDP	2-oxoisovalerate dehydrogenase subunit alpha	1.2.4.4	0.467
1umc	TDP	2-oxoisovalerate dehydrogenase subunit beta	1.2.4.4	0.467
3lq4	TDP	Pyruvate dehydrogenase E1 component	1.2.4.1	0.450
2g28	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.441