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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1t9b1CSAcetolactate synthase catalytic subunit, mitochondrial2.2.1.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1t9b1CSAcetolactate synthase catalytic subunit, mitochondrial2.2.1.61.000
1t9c1SMAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.612
1n0hCIEAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.558
1t9a1TBAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.553