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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1t7o152Carnitine O-acetyltransferase2.3.1.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1t7o152Carnitine O-acetyltransferase2.3.1.71.000
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.647
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.579
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.559
3mjrAC2Deoxycytidine kinase2.7.1.740.518
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.516
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.515
1h51FMNPentaerythritol tetranitrate reductase/0.514
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.513
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.513
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.513
1h50FMNPentaerythritol tetranitrate reductase/0.511
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.509
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.509
2whqHI6Acetylcholinesterase3.1.1.70.505
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.503
3p8iFMNPentaerythritol tetranitrate reductase/0.501
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.500
1x1aSAMC-20 methyltransferase/0.499
5stdUNNScytalone dehydratase4.2.1.940.499
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.498
3mj4URMUDP-galactopyranose mutase/0.497
3p62FMNPentaerythritol tetranitrate reductase/0.497
2cekN8TAcetylcholinesterase3.1.1.70.496
2gv8NDPThiol-specific monooxygenase1.14.130.495
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.495
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.495
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.494
2il2LIXRenin3.4.23.150.494
2iviACWIsopenicillin N synthase1.21.3.10.493
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.493
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.493
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.492
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.492
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.492
1icpFMN12-oxophytodienoate reductase 11.3.1.420.489
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.489
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.489
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.489
3stdMQ0Scytalone dehydratase4.2.1.940.489
1bk0ACVIsopenicillin N synthase1.21.3.10.488
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.488
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.488
2abbFMNPentaerythritol tetranitrate reductase/0.487
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.487
4araC56Acetylcholinesterase3.1.1.70.487
4bb3KKAIsopenicillin N synthase1.21.3.10.487
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.486
2xnvVU3Soluble acetylcholine receptor/0.486
2h15B19Carbonic anhydrase 24.2.1.10.485
2q92B23Methionine aminopeptidase/0.485
3p74FMNPentaerythritol tetranitrate reductase/0.485
3vswR31Renin3.4.23.150.485
1icqFMN12-oxophytodienoate reductase 11.3.1.420.484
2g1s4IGRenin3.4.23.150.484
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.484
4ey6GNTAcetylcholinesterase3.1.1.70.484
1hb3SCVIsopenicillin N synthase1.21.3.10.483
2g1n1IGRenin3.4.23.150.483
3b6pTMPThree-prime repair exonuclease 13.1.11.20.483
7stdCRPScytalone dehydratase4.2.1.940.483
1x1bSAHC-20 methyltransferase/0.482
2vbdV10Isopenicillin N synthase1.21.3.10.482
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.481
2g1y5IGRenin3.4.23.150.481
2jb4A14Isopenicillin N synthase1.21.3.10.481
4c49HCYCorticosteroid-binding globulin/0.481
2j3qTFLAcetylcholinesterase3.1.1.70.480
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.480
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.480
3h3qH13Collagen type IV alpha-3-binding protein/0.480
4psbGA3Cytokinin-specific binding protein/0.479
1rfuADPPyridoxal kinase2.7.1.350.478
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.478
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.478
4dvi2IWTankyrase-12.4.2.300.478
3f03FMNPentaerythritol tetranitrate reductase/0.477
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.477
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.477
4g8jTHMUridine phosphorylase/0.477
1hb1OCVIsopenicillin N synthase1.21.3.10.476
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.476
2vcmM11Isopenicillin N synthase1.21.3.10.476
4m83ERYOleandomycin glycosyltransferase2.4.10.476
1fxsNAPGDP-L-fucose synthase/0.475
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.475
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.475
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.475
3mauEXTPutative sphingosine-1-phosphate lyase/0.475
3qt62P0Mevalonate diphosphate decarboxylase/0.475
4df2FMNNADPH dehydrogenase/0.475
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.475
1gky5GPGuanylate kinase2.7.4.80.474
2dxdANPNucleoside diphosphate kinase2.7.4.60.474
2g8yNADHydroxycarboxylate dehydrogenase B/0.474
2xytTC9Soluble acetylcholine receptor/0.474
3n19FNRXenobiotic reductase/0.474
3q9bB3NAcetylpolyamine amidohydrolase/0.474
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.473
2wzySQXSoluble acetylcholine receptor/0.473
3gwfNAPCyclohexanone monooxygenase/0.473
4q0kGA3Phytohormone-binding protein/0.473
5fd8A5APutative carboxypeptidase yocD/0.473
1q45FMN12-oxophytodienoate reductase 31.3.1.420.472
1w34FADFerredoxin--NADP reductase1.18.1.20.472
2xukTZ5Acetylcholinesterase3.1.1.70.472
4du82P0Mevalonate diphosphate decarboxylase/0.472
1ex75GPGuanylate kinase2.7.4.80.471
1x8lOXRRetinol dehydratase/0.471
2ea2F77Methionine aminopeptidase 2/0.471
3p67FMNPentaerythritol tetranitrate reductase/0.471
3zoiM2WIsopenicillin N synthase1.21.3.10.471
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.470
1icsFMN12-oxophytodienoate reductase 11.3.1.420.470
1u1gBBBUridine phosphorylase2.4.2.30.470
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.470
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.470
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.470
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.470
3to3ATPPetrobactin biosynthesis protein AsbB/0.470
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.470
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.470
4p9dTMPDeoxycytidylate deaminase/0.470
1itzTPPTransketolase, chloroplastic2.2.1.10.469
1obnASVIsopenicillin N synthase1.21.3.10.469
2iko7IGRenin3.4.23.150.469
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.469
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.468
1h22E10Acetylcholinesterase3.1.1.70.468
1h63FMNPentaerythritol tetranitrate reductase/0.468
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.468
2stdCRPScytalone dehydratase4.2.1.940.468
2vbpVB1Isopenicillin N synthase1.21.3.10.468
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.467
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.467
1ry0PG2Aldo-keto reductase family 1 member C3/0.467
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.467
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.467
2xupTZ5Acetylcholinesterase3.1.1.70.467
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.467
3fhxPLPPyridoxal kinase2.7.1.350.467
3v2uATPProtein GAL3/0.467
3zkyWT4Isopenicillin N synthase1.21.3.10.467
4m0f1YKAcetylcholinesterase3.1.1.70.467
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.466
2evmFC2Methionine aminopeptidase/0.466
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.466
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.466
3sfxJANUncharacterized protein/0.466
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.466
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.465
1qiqACCIsopenicillin N synthase1.21.3.10.465
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.465
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.465
3qe2FMNNADPH--cytochrome P450 reductase/0.465
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.465
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
1rzuADPGlycogen synthase 12.4.1.210.464
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.464
1toiHCIAspartate aminotransferase2.6.1.10.464
2gg8U15Methionine aminopeptidase/0.464
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.464
3gkaFMNN-ethylmaleimide reductase/0.464
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.464
4gddNAIUDP-galactopyranose mutase/0.464
1r58AO5Methionine aminopeptidase 2/0.463
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.463
1tkaN3TTransketolase 12.2.1.10.463
3dcsMZMCarbonic anhydrase 24.2.1.10.463
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.463
3ziuLSSLeucyl-tRNA synthetase/0.463
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1q84TZ4Acetylcholinesterase3.1.1.70.462
1txtCAAHMG-CoA synthase/0.462
1vyrFMNPentaerythritol tetranitrate reductase/0.462
1x1cSAHC-20 methyltransferase/0.462
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
2e0nSAHPrecorrin-2 C20-methyltransferase/0.462
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.462
2vn1FK5Peptidylprolyl isomerase/0.462
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.462
2xveFADPutative flavin-containing monooxygenase/0.462
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3fhxPXLPyridoxal kinase2.7.1.350.462
3sxjSAMPutative methyltransferase/0.462
4a802ANMajor pollen allergen Bet v 1-A/0.462
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.462
4n4v2GYTankyrase-12.4.2.300.462
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.462
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.462
1fm4DXCMajor pollen allergen Bet v 1-L/0.461
1rneC60Renin3.4.23.150.461
1s63778Protein farnesyltransferase subunit beta2.5.1.580.461
2g247IGRenin3.4.23.150.461
2qimZEAClass 10 plant pathogenesis-related protein/0.461
2xuqTZ4Acetylcholinesterase3.1.1.70.461
4gd40WSLysine-specific demethylase 4A1.14.110.461
1culFOKAdenylate cyclase type 2/0.460
1culFOKAdenylate cyclase type 5/0.460
1e66HUXAcetylcholinesterase3.1.1.70.460
1eveE20Acetylcholinesterase3.1.1.70.460
1odcA8BAcetylcholinesterase3.1.1.70.460
1s36CEIObelin/0.460
2xuiTZ5Acetylcholinesterase3.1.1.70.460
2y60M8FIsopenicillin N synthase1.21.3.10.460
2y6fM9FIsopenicillin N synthase1.21.3.10.460
3qj0QI3Botulinum neurotoxin type A3.4.24.690.460
3sfy3FYUncharacterized protein/0.460
3t82SG4Carbonic anhydrase 24.2.1.10.460
4jlm1NNDeoxycytidine kinase2.7.1.740.460
1h60STRPentaerythritol tetranitrate reductase/0.459
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.459
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.459
2xysSY9Soluble acetylcholine receptor/0.459
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.459
3wqmB29Diterpene synthase3.1.7.80.459
4ax9N5NProthrombin3.4.21.50.459
4dbc3QPAspartate aminotransferase2.6.1.10.459
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.459
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.459
4iae1DXAlr2278 protein/0.459
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.459
1yw8A75Methionine aminopeptidase 2/0.458
2c20NADUDP-glucose 4-epimerase/0.458
2g263LGRenin3.4.23.150.458
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.458
2po3T4K4-dehydrase/0.458
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4b63NAPL-ornithine N(5)-monooxygenase/0.458
4uymVOR14-alpha sterol demethylase Cyp51B/0.458
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1by5GLY_GLY_GLY_AHO_AHO_AHO_FEFerrichrome-iron receptor/0.457
1sb1165Prothrombin3.4.21.50.457
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2aot2PMHistamine N-methyltransferase2.1.1.80.457
2g1o2IGRenin3.4.23.150.457
2gvdFKPAdenylate cyclase type 2/0.457
2gvdFKPAdenylate cyclase type 5/0.457
2rqfJH3Hemolymph juvenile hormone binding protein/0.457
2xi4AFTAcetylcholinesterase3.1.1.70.457
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
3k8q22APurine nucleoside phosphorylase2.4.2.10.457
3p5pA3CTaxadiene synthase4.2.3.170.457
3p80P80Pentaerythritol tetranitrate reductase/0.457
3q8uADPNucleoside diphosphate kinase/0.457
3vmmP0DAlanine--anticapsin ligase/0.457
4bfxZVXPantothenate kinase2.7.1.330.457
4e2xTYDMethyltransferase/0.457
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.457
4uugPXGBranched-chain amino acid aminotransferase, putative/0.457
4w5kPLPAspartate aminotransferase, mitochondrial/0.457
1qtiGNTAcetylcholinesterase3.1.1.70.456
2b58COADiamine acetyltransferase 1/0.456
2g226IGRenin3.4.23.150.456
2qc8ADPGlutamine synthetase6.3.1.20.456
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
2zcvNDPQuinone oxidoreductase 21.6.5.20.456
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.456
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.456
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.456
3ekuCY9Actin-5C/0.456
3h3t16HCollagen type IV alpha-3-binding protein/0.456
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.456
3p82FMNPentaerythritol tetranitrate reductase/0.456
3vydVYDRenin3.4.23.150.456
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.456
4a83DXCMajor pollen allergen Bet v 1-A/0.456
4gdcNDPUDP-galactopyranose mutase/0.456
4jlj1NMDeoxycytidine kinase2.7.1.740.456
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.456
4q71FADBifunctional protein PutA/0.456
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
2ea4F79Methionine aminopeptidase 2/0.455
2gs9SAHUncharacterized protein/0.455
2gyuHI6Acetylcholinesterase3.1.1.70.455
2xugTZ4Acetylcholinesterase3.1.1.70.455
3h3r14HCollagen type IV alpha-3-binding protein/0.455
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.455
3lqfNADGalactitol dehydrogenase/0.455
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.455
3vyfVYFRenin3.4.23.150.455
3zv7NHGAcetylcholinesterase3.1.1.70.455
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.455
4rp8ASCAscorbate-specific PTS system EIIC component/0.455
4xr9NADCalS8/0.455
4yaoFMNNADPH--cytochrome P450 reductase/0.455
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.454
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.454
1fmjRTLRetinol dehydratase/0.454
1xvaSAMGlycine N-methyltransferase2.1.1.200.454
2a3cPNXEndochitinase B13.2.1.140.454
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.454
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.454
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.454
2w6cBM4Acetylcholinesterase3.1.1.70.454
2xuoTZ4Acetylcholinesterase3.1.1.70.454
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.454
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.454
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3p84FMNPentaerythritol tetranitrate reductase/0.454
4bfzZVZPantothenate kinase2.7.1.330.454
4dc0NDPPutative ketoacyl reductase1.3.10.454
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.454
1fkiSB1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.453
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.453
1gtrATPGlutamine--tRNA ligase6.1.1.180.453
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1zgbA1EAcetylcholinesterase3.1.1.70.453
2bu9HFVIsopenicillin N synthase1.21.3.10.453
2ggbU17Methionine aminopeptidase/0.453
2jh6894Prothrombin3.4.21.50.453
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.453
2uxoTACHTH-type transcriptional regulator TtgR/0.453
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
2xufTZ4Acetylcholinesterase3.1.1.70.453
2y05RALProstaglandin reductase 1/0.453
3af1GDPPantothenate kinase2.7.1.330.453
3nutSAHPrecorrin-3 methylase/0.453
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.453
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.453
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.453
4drp0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.453
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.453
5c1mCLRMu-type opioid receptor/0.453
4daj0HKMuscarinic acetylcholine receptor M3/0.453
1bwsNDPGDP-L-fucose synthase/0.452
1udaUFGUDP-glucose 4-epimerase5.1.3.20.452
2bvs2CEProthrombin3.4.21.50.452
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.452
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.452
2q96A18Methionine aminopeptidase/0.452
2vd7PD2Lysine-specific demethylase 4A1.14.110.452
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3hdyGDUUDP-galactopyranose mutase/0.452
3pkeY10Methionine aminopeptidase 2/0.452
3ufl508Beta-secretase 13.4.23.460.452
4bfyZVYPantothenate kinase2.7.1.330.452
4r81FMNPredicted NADH dehydrogenase/0.452
5a0112VO-glycosyltransferase/0.452
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.451
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.451
1tllFMNNitric oxide synthase, brain1.14.13.390.451
2g1r3IGRenin3.4.23.150.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.451
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
2wwjY28Lysine-specific demethylase 4A/0.451
2xujTZ5Acetylcholinesterase3.1.1.70.451
3apwDP0Alpha-1-acid glycoprotein 2/0.451
3bk2U5PRibonuclease J/0.451
3fr5I4AFatty acid-binding protein, adipocyte/0.451
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.451
3qvrFADGlucose oxidase1.1.3.40.451
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.451
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.451
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.451
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.451
4ey7E20Acetylcholinesterase3.1.1.70.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4j4nD44Peptidylprolyl isomerase/0.451
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
1nhkCMPNucleoside diphosphate kinase2.7.4.60.450
1u1f183Uridine phosphorylase2.4.2.30.450
2aouCQAHistamine N-methyltransferase2.1.1.80.450
2evcFC3Methionine aminopeptidase/0.450
2q93B21Methionine aminopeptidase/0.450
2vq7NAPPutative flavin-containing monooxygenase/0.450
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.450
3c27DKKProthrombin3.4.21.50.450
3h0bB35Beta-secretase 13.4.23.460.450
3mauPLRPutative sphingosine-1-phosphate lyase/0.450
3ukfGDUUDP-galactopyranose mutase/0.450
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.450
4bfvZVVPantothenate kinase2.7.1.330.450
4kbyC2EStimulator of interferon genes protein/0.450
1e2nRCAThymidine kinase/0.449
1fmlRTLRetinol dehydratase/0.449
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1nm6L86Prothrombin3.4.21.50.449
1u65CP0Acetylcholinesterase3.1.1.70.449
1vkgCRIHistone deacetylase 83.5.1.980.449
1w76GNTAcetylcholinesterase3.1.1.70.449
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.449
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.449
2gevCOKPantothenate kinase2.7.1.330.449
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.449
3c1oNAPEugenol synthase/0.449
3d27W29Methionine aminopeptidase/0.449
3gf4UPGUDP-galactopyranose mutase5.4.99.90.449
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.449
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.449
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.449
3mytEQUSteroid Delta-isomerase5.3.3.10.449
3pl8FADPyranose 2-oxidase/0.449
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.449
3qviK95HAP protein/0.449
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.449
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.449
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4zwpM44Xaa-Pro dipeptidase3.4.13.90.449
6stdMS2Scytalone dehydratase4.2.1.940.449
1blzACVIsopenicillin N synthase1.21.3.10.448
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.448
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.448
1l7x700Glycogen phosphorylase, liver form2.4.1.10.448
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.448
1qrsATPGlutamine--tRNA ligase6.1.1.180.448
1yw9A84Methionine aminopeptidase 2/0.448
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.448
2ckmAA7Acetylcholinesterase3.1.1.70.448
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.448
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.448
2vyqFADFerredoxin--NADP reductase1.18.1.20.448
2zhf49UProthrombin3.4.21.50.448
3aho3A2Oligopeptidase/0.448
3iogSDFMetallo-beta-lactamase type 2/0.448
3oafOAGDihydrofolate reductase1.5.1.30.448
3otwCOAPhosphopantetheine adenylyltransferase/0.448
3q7fED2Uncharacterized protein/0.448
3rvhHQ2Lysine-specific demethylase 4A1.14.110.448
3t70DU4Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.448
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.448
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.448
4bfwZVWPantothenate kinase2.7.1.330.448
4h6pFMNChromate reductase/0.448
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.448
1a9cGTPGTP cyclohydrolase 13.5.4.160.447
1aiqCB3Thymidylate synthase/0.447
1ay0TPPTransketolase 12.2.1.10.447
2ab8MTPAdenosine kinase2.7.1.200.447
2e77FMNLactate oxidase/0.447
2gesCOKPantothenate kinase2.7.1.330.447
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.447
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.447
3qeoLLTDeoxycytidine kinase2.7.1.740.447
3t85SG7Carbonic anhydrase 24.2.1.10.447
3zeiAWHO-acetylserine sulfhydrylase/0.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.447
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.447
4u163C0Muscarinic acetylcholine receptor M3/0.447
1cs4FOKAdenylate cyclase type 2/0.446
1cs4FOKAdenylate cyclase type 5/0.446
1h61PDNPentaerythritol tetranitrate reductase/0.446
1icqOPD12-oxophytodienoate reductase 11.3.1.420.446
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.446
1o9bNAIQuinate/shikimate dehydrogenase/0.446
1pl6572Sorbitol dehydrogenase1.1.1.140.446
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.446
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.446
1vi2NADQuinate/shikimate dehydrogenase/0.446
1zsbAZMCarbonic anhydrase 24.2.1.10.446
2ejvNADL-threonine 3-dehydrogenase/0.446
2gg0U11Methionine aminopeptidase/0.446
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.446
2ifaFMNUncharacterized protein/0.446
2pncCLUPrimary amine oxidase, liver isozyme/0.446
2rhrEMOPutative ketoacyl reductase1.3.10.446
2vrbNAPTriphenylmethane reductase/0.446
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.446
2xuhTZ4Acetylcholinesterase3.1.1.70.446
3g0cRUFDipeptidyl peptidase 4/0.446
3g0gRUMDipeptidyl peptidase 4/0.446
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.446
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4iarERM5-hydroxytryptamine receptor 1B/0.446
4ise1FWGlucokinase2.7.1.20.446
4qak2AMRNA 2',3'-cyclic phosphodiesterase/0.446
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.446
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.446
4zlaBESCytosol aminopeptidase3.4.11.10.446
5czySAMEukaryotic huntingtin interacting protein B/0.446
1d9i00PProthrombin3.4.21.50.445
1if8SBSCarbonic anhydrase 24.2.1.10.445
1psa0ZLPepsin A3.4.23.10.445
1rctNOSPurine nucleoside phosphorylase2.4.2.10.445
1rftPXMPyridoxal kinase2.7.1.350.445
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.445
1votHUPAcetylcholinesterase3.1.1.70.445
1x1dSAHC-20 methyltransferase/0.445
1ypgUIRProthrombin3.4.21.50.445
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.445
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.445
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.445
2lfoGCHFatty acid-binding protein, liver/0.445
2p99YE6Methionine aminopeptidase/0.445
2v3oI26Prothrombin3.4.21.50.445
2zt5B4PGlycine--tRNA ligase/0.445
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3w78CBDFMN-dependent NADH-azoreductase/0.445
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.445
4b64NAPL-ornithine N(5)-monooxygenase/0.445
4dh0MR8Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4g090VDHistidinol dehydrogenase/0.445
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.445
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.445
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.445
1cnyEG3Carbonic anhydrase 24.2.1.10.444
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1g1dFSBCarbonic anhydrase 24.2.1.10.444
1gaxVAAValine--tRNA ligase6.1.1.90.444
1l5s700Glycogen phosphorylase, liver form2.4.1.10.444
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.444
1qrtATPGlutamine--tRNA ligase6.1.1.180.444
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.444
1w4lGL8Acetylcholinesterase3.1.1.70.444
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.444
2qw034Z4-chlorobenzoyl CoA ligase/0.444
2x92X92Angiotensin-converting enzyme3.4.15.10.444
2xy93ESAngiotensin-converting enzyme3.2.10.444
3dhk23UProthrombin3.4.21.50.444
3k2fNKXCarbonic anhydrase 24.2.1.10.444
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3nsh957Beta-secretase 13.4.23.460.444
3uayADNPurine nucleoside phosphorylase DeoD-type/0.444
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
3zkuHCVIsopenicillin N synthase1.21.3.10.444
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.444
4ejvLCLTranscriptional regulator TcaR/0.444
4i0i957Beta-secretase 13.4.23.460.444
4jicFMNGTN Reductase/0.444
4jtqNAPAldo-keto reductase family 1 member C2/0.444
4mfeBTNPyruvate carboxylase/0.444
4phlPILPhosphodiesterase/0.444
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
4zowCLMMultidrug transporter MdfA/0.444
1bim0QBRenin3.4.23.150.443
1cf3FADGlucose oxidase1.1.3.40.443
1cjvFOKAdenylate cyclase type 2/0.443
1cjvFOKAdenylate cyclase type 5/0.443
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.443
1j49NADD-lactate dehydrogenase1.1.1.280.443
1okmSABCarbonic anhydrase 24.2.1.10.443
1oq5CELCarbonic anhydrase 24.2.1.10.443
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.443
1vbiNADMalate/L-lactate dehydrogenase family protein/0.443
2c6c24IGlutamate carboxypeptidase 23.4.17.210.443
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.443
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
2i4qUA4Renin3.4.23.150.443
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.443
2x90EALAngiotensin-converting enzyme3.4.15.10.443
2xweAMFGlucosylceramidase3.2.1.450.443
3c3xNAPEugenol synthase 11.1.1.3180.443
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.443
3gfbNADL-threonine 3-dehydrogenase/0.443
3k1wBFXRenin3.4.23.150.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.443
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4cdmFO1Deoxyribodipyrimidine photolyase/0.443
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.443
4m5pFMNNADPH dehydrogenase/0.443
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.443
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.443
1a4wQWEProthrombin3.4.21.50.442
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.442
1m13HYFNuclear receptor subfamily 1 group I member 2/0.442
1mrkFMCRibosome-inactivating protein alpha-trichosanthin3.2.2.220.442
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.442
1qtqQSIGlutamine--tRNA ligase6.1.1.180.442
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.442
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
2ikuLIYRenin3.4.23.150.442
2oazI96Methionine aminopeptidase 2/0.442
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.442
2xyd3ESAngiotensin-converting enzyme3.2.10.442
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
3bi2FADPolyamine oxidase FMS1/0.442
3c14FOKAdenylate cyclase type 2/0.442
3c14FOKAdenylate cyclase type 5/0.442
3fktSIIBeta-secretase 13.4.23.460.442
3hkuTORCarbonic anhydrase 24.2.1.10.442
3keqNADRedox-sensing transcriptional repressor Rex/0.442
3kigDA4Carbonic anhydrase 24.2.1.10.442
3r8hZOMAldo-keto reductase family 1 member C3/0.442
4bftZVTPantothenate kinase2.7.1.330.442
4fm80UQBeta-secretase 13.4.23.460.442
4ke11R6Beta-secretase 13.4.23.460.442
4m0cFMNFMN-dependent NADH-azoreductase 1/0.442
4nv10FXFormyl transferase/0.442
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.442
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.441
1g54FFBCarbonic anhydrase 24.2.1.10.441
1gvrTNLPentaerythritol tetranitrate reductase/0.441
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1if6FBUCarbonic anhydrase 24.2.1.10.441
1kkq471Peroxisome proliferator-activated receptor alpha/0.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.441
1r5gAO1Methionine aminopeptidase 2/0.441
1tkcM6TTransketolase 12.2.1.10.441
1yryMSGPurine nucleoside phosphorylase2.4.2.10.441
2anb5GPGuanylate kinase2.7.4.80.441
2ga2A19Methionine aminopeptidase 2/0.441
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.441
2q94A04Methionine aminopeptidase/0.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
2uxiG50HTH-type transcriptional regulator TtgR/0.441
2zb3NDPProstaglandin reductase 21.3.1.480.441
3dc3AZMCarbonic anhydrase 24.2.1.10.441
3g72A6TRenin3.4.23.150.441
3h59H59Genome polyprotein2.7.7.480.441
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.441
3q43D66M1 family aminopeptidase3.4.110.441
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
3sbhE65Carbonic anhydrase 24.2.1.10.441
4askK0ILysine-specific demethylase 6B1.14.110.441
4bfsZVSPantothenate kinase2.7.1.330.441
4lutDCSAlanine racemase/0.441
4lxb7R9Prothrombin3.4.21.50.441
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.441
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.441
5c4fUPGHisto-blood group ABO system transferase/0.441
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.441
4xnw2IDP2Y purinoceptor 1/0.441
4mqt2CUMuscarinic acetylcholine receptor M2/0.441
1amoFMNNADPH--cytochrome P450 reductase/0.440
1bwkFMNNADPH dehydrogenase 11.6.99.10.440
1d6w00RProthrombin3.4.21.50.440
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.440
1h62ANBPentaerythritol tetranitrate reductase/0.440
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
2dg3RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
2g274LGRenin3.4.23.150.440
2iyfERYOleandomycin glycosyltransferase2.4.10.440
2jh5895Prothrombin3.4.21.50.440
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.440
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.440
2v58LZJBiotin carboxylase6.3.4.140.440
2vetUMPThymidylate synthase/0.440
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.440
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.440
3pd4A3GThreonine--tRNA ligase6.1.1.30.440
3w3lRX8Toll-like receptor 8/0.440
3wagTYDGlycosyltransferase/0.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4h1q0XXMatrix metalloproteinase-93.4.24.350.440
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.440
5choFADFlavin reductase/0.440