Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 1.000 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.558 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.546 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.537 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.531 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.530 | |
| 3ag9 | A02 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.523 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.522 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.520 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.515 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.515 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.515 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.513 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.512 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.511 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.510 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.510 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.508 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.508 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.506 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.506 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.506 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.506 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.506 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.505 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.505 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.504 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.503 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.502 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.501 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.501 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.500 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.500 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.500 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.499 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.499 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.498 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.498 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.497 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.497 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.496 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.496 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.495 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.495 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.495 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.493 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.493 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.493 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.492 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.492 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.491 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.491 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.490 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.490 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.489 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.489 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.489 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.488 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.488 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.487 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.487 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.486 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.486 | |
| 3krw | BA1 | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.486 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.485 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.483 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.483 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.482 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.482 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.482 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.481 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.480 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.480 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.479 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.477 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.477 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.476 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.475 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.475 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.474 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.474 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.474 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.473 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.473 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.472 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.472 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.472 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.471 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.471 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.470 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.470 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.470 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.470 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.470 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.470 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.469 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.469 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.469 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.469 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.468 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.468 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.468 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.468 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.467 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.467 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 4i0t | 1B6 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.467 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.467 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.466 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.466 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.466 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.465 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.465 | |
| 3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.465 | |
| 4fux | E75 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.465 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.463 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.463 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.463 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.463 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.462 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.462 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.462 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.462 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.461 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.460 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.460 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.459 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.459 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.458 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.458 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.458 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.458 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.458 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.457 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.457 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.457 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.457 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.457 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.456 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.456 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3qai | XNN | Ketohexokinase | / | 0.456 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 4b7t | CWT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.454 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.454 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.453 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.452 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.452 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.452 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.451 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.451 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4fto | 3HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.450 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 2ydk | YDK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.449 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.448 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.448 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.447 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.447 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2fgi | PD1 | Fibroblast growth factor receptor 1 | / | 0.446 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.446 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.445 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.445 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.445 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.445 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.444 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 5a3b | APR | SIR2 family protein | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3pvw | QRX | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.443 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4pd6 | URI | Nucleoside permease | / | 0.443 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.441 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 3js2 | VM1 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.440 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.440 |